Holistic Remedies · Ingredient
Fucoxanthin
Formula: C42H58O6 · MW: 658.9200000000002 · Drug-likeness: 0.076
⚗️ Identity
Name
Fucoxanthin
Aliases / Synonyms
3351-86-8; all-trans-Fucoxanthin; 06O0TC0VSM; CHEBI:5186; (3'S,5'R,6'R)-3'-acetoxy-5,6-epoxy-3,5'-dihydroxy-6',7'-didehydro-5,6,7,8,5',6'-hexahydro-beta,beta-caroten-8-one; (1S,3R)-3-hydroxy-4-((3E,5E,7E,9E,11E,13E,15E)-18-((1S,4S,6R)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl)-3,7,12,16-tetramethyl-17-oxooctadeca-1,3,5,7,9,11,13,15-octaen-1-ylidene)-3,5,5-trimethylcyclohexyl acetate; (3S,3'S,5R,5'R,6S,6'R)-3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7...
🧪 Chemistry
Molecular Weight
658.9200
LogP
8.6922
Drug-likeness
0.076
H-Bond Acceptors
6
H-Bond Donors
2
Rotatable Bonds
11
🔗 External References
1
Clinical Trials
0
Meta-Analyses
17
PubMed References
Top Conditions Studied with Fucoxanthin
📋 Sample Trials
NCT03613740
Effect of Fucoxanthin on the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
Active_Not_Recruiting · Phase 2 · Metabolic Syndrome
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 24760606
Inhibitory effects of fucoxanthinol on the viability of human breast cancer cell lines MCF-7 and MDA-MB-231 are correlated with modulation of the NF-kappaB pathway
Cell Biol Toxicol · 2014
PMID 21078541
Fucoxanthin and its deacetylated product, fucoxanthinol, induce apoptosis of primary effusion lymphomas
Cancer Lett · 2011
PMID 32033492
Skin Irritation Testing beyond Tissue Viability: Fucoxanthin Effects on Inflammation, Homeostasis, and Metabolism
Pharmaceutics · 2020
PMID 32232236
Fucoxanthin alleviates palmitate-induced inflammation in RAW 264.7 cells through improving lipid metabolism and attenuating mitochondrial dysfunction
Food Funct · 2020
PMID 32235696
Fucoxanthin Ameliorates Atopic Dermatitis Symptoms by Regulating Keratinocytes and Regulatory Innate Lymphoid Cells
Int J Mol Sci · 2020
PMID 32876840
Fucoxanthin Mitigates Subarachnoid Hemorrhage-Induced Oxidative Damage via Sirtuin 1-Dependent Pathway
Mol Neurobiol · 2020