Holistic Remedies · Ingredient
Gentiopicroside
Formula: C16H20O9 · MW: 356.3270000000001 · Drug-likeness: 0.344
⚗️ Identity
Name
Gentiopicroside
Aliases / Synonyms
Gentiopicrin; 20831-76-9; UNII-0WE09Z21RC; 0WE09Z21RC; CHEBI:5321; DTXSID40878043; EINECS 244-070-2; NSC 606402; NSC-606402
🧪 Chemistry
Molecular Weight
356.3270
LogP
-1.6715
Drug-likeness
0.344
Oral Bioavailability
5.9040
H-Bond Acceptors
9
H-Bond Donors
4
Rotatable Bonds
4
🔗 External References
0
Clinical Trials
0
Meta-Analyses
9
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 31759089
Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy
Pharmacol Res · 2020
PMID 32477105
Anti-Rheumatic Properties of Gentiopicroside Are Associated With Suppression of ROS-NF-κB-NLRP3 Axis in Fibroblast-Like Synoviocytes and NF-κB Pathway in Adjuvant-Induced Arthritis
Front Pharmacol · 2020
PMID 32655764
Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation
Oxid Med Cell Longev · 2020
PMID 32832008
Gentiopicroside, a Secoiridoid Glycoside from Gentiana rigescens Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress
Oxid Med Cell Longev · 2020
PMID 33130083
Hepatoprotective effect of gentiopicroside in combination with leflunomide and/or methotrexate in arthritic rats
Life Sci · 2021
PMID 34783166
Gentiopicroside promotes the osteogenesis of bone mesenchymal stem cells by modulation of β-catenin-BMP2 signalling pathway
J Cell Mol Med · 2021