natural remedies · Ingredient
(-)-gossypol
Formula: C30H30O8 · MW: 518.5620000000004 · Drug-likeness: 0.131
⚗️ Identity
Name
(-)-gossypol
Aliases / Synonyms
gossypol; 303-45-7; 90141-22-3; Pogosin; (+)-Gossypol; Tash 1; (R)-Gossypol; (R)-(-)-Gossypol; (+/-)-Gossypol
🧪 Chemistry
Molecular Weight
518.5620
LogP
6.3822
Drug-likeness
0.131
H-Bond Acceptors
8
H-Bond Donors
6
Rotatable Bonds
5
🔗 External References
3
Clinical Trials
1
Meta-Analyses
0
PubMed References
Top Conditions Studied with (-)-gossypol
📋 Sample Trials
NCT00891072
Gossypol, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Completed · Phase 1 · Adult Grade III Lymphomatoid Granulomato
NCT00390403
Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Completed · Phase 1 · Brain and Central Nervous System Tumors
NCT00540722
Gossypol in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
Completed · Phase 2 · Adult Giant Cell Glioblastoma|Adult Glio
📊 Sample Meta-Analyses
CRD42021297142
Systematic Review of Gossypol / AT-101 in Cancer Clinical Trials
Various types of cancer, plant compound
📚 Sample References
None linked yet.