Holistic Remedies · Ingredient
H-met-h
Formula: C5H11NO2S · MW: 149.215 · Drug-likeness: 0.597
⚗️ Identity
Name
H-met-h
Aliases / Synonyms
L-methionine; 63-68-3; methionine; h-Met-oh; (S)-2-Amino-4-(methylthio)butanoic acid; Cymethion; L-(-)-Methionine; S-Methionine; Liquimeth; Neo-methidin
🧪 Chemistry
Molecular Weight
149.2150
LogP
0.1514
Drug-likeness
0.597
Oral Bioavailability
70.8660
H-Bond Acceptors
3
H-Bond Donors
2
Rotatable Bonds
4
🔗 External References
9
Clinical Trials
5
Meta-Analyses
7
PubMed References
Top Conditions Studied with H-met-h
Patients with glioma that have undergone a MET PET study. 1
Brain Tumors and/or Solid Tumors Including|Brain Stem Glioma 1
Multiple myeloma, accounting for approximately 10% of hemato 1
Brain Cancer|CNS Cancer 1
Lung cancer is the most common cancer and a leading cause of 1
Breast cancer risk 1
Urinary Tract Infection|Pelvic Organ Prolapse|Urinary Incont 1
Unipolar Depression 1
Pulmonary Alveolar Proteinosis|Mutation Ala393Thr of the MAR 1
Pregnancy Related 1
Myelopathy|AIDS-Myelopathy|AIDS Vacuolar Myelopathy 1
Metabolic Syndrome 1
📋 Sample Trials
NCT00032695
Treatment of AIDS Vacuolar Myelopathy With Methionine
Completed · Phase 3 · Myelopathy|AIDS-Myelopathy|AIDS Vacuolar
NCT00597246
Imaging Brain Tumors With FACBC and Methionine
Completed · Brain Cancer|CNS Cancer
NCT00840047
Methionine PET/CT Studies In Patients With Cancer
Active_Not_Recruiting · Phase 2 · Brain Tumors and/or Solid Tumors Includi
NCT02216253
L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract to Prevent Postoperative Urinary Tract Infection.
Completed · Urinary Tract Infection|Pelvic Organ Pro
NCT02566434
Methionine Tolerance in Healthy Human Adults
Completed · Healthy
NCT03887169
Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene.
Completed · Phase 1|Phase 2 · Pulmonary Alveolar Proteinosis|Mutation
📊 Sample Meta-Analyses
CRD42019123111
The association between dietary intakes of methionine, choline and betaine and breast cancer risk: a systematic review and meta-analysis
Breast cancer risk
CRD42015019955
S-adenosyl methionine (SAM-e) for depression in adults [Cochrane Protocol]
The Cochrane Depression, Anxiety and Neurosis Group
CRD42020195977
Performance of 11C-methionine PET imaging for detecting multiple myeloma
Multiple myeloma, accounting for approximately 10% of hematological malignancies
CRD42018086654
Serum B vitamins (B6, B9, B12), homocysteine and methionine—involved in one-carbon metabolism—associated with the risk of lung cancer: a systematic review and meta-analysis
Lung cancer is the most common cancer and a leading cause of cancer-related mort
CRD42016050747
11C-methionine PET in the discrimination between low-grade glioma and high-grade glioma
Patients with glioma that have undergone a MET PET study.
📚 Sample References
PMID 31961063
Methionine Commits Cells to Differentiate Into Plasmablasts Through Epigenetic Regulation of BTB and CNC Homolog 2 by the Methyltransferase EZH2
Arthritis Rheumatol · 2020
PMID 32160926
Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study
J Transl Med · 2020
PMID 32533465
Withdrawal Effects Following Methionine Exposure in Adult Zebrafish
Mol Neurobiol · 2020
PMID 32790060
Dietary methionine restriction attenuates renal ischaemia/reperfusion-induced myocardial injury by activating the CSE/H2S/ERS pathway in diabetic mice
J Cell Mol Med · 2020
PMID 32879489
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation
Nature · 2020
PMID 33207837
Methionine Supplementation Affects Metabolism and Reduces Tumor Aggressiveness in Liver Cancer Cells
Cells · 2020
🏥 Linked Health Topics 1 · matched via study conditions