Holistic Remedies · Ingredient
Hispolon
Formula: C12H12O4 · MW: 220.224 · Drug-likeness: 0.315
⚗️ Identity
Name
Hispolon
Aliases / Synonyms
173933-40-9; HISPOLON(P); (3Z,5E)-6-(3,4-dihydroxyphenyl)-4-hydroxyhexa-3,5-dien-2-one; (3Z,5E)-6-(3,4-dihydroxyphenyl)-4-hydroxy-hexa-3,5-dien-2-one; CHEMBL452722; SCHEMBL15917284; SCHEMBL20978310; CHEBI:212795; DTXSID701045719
🧪 Chemistry
Molecular Weight
220.2240
LogP
2.1419
Drug-likeness
0.315
H-Bond Acceptors
4
H-Bond Donors
3
Rotatable Bonds
3
🔗 External References
0
Clinical Trials
0
Meta-Analyses
3
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 28981104
Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells
Cell Death Dis · 2017
PMID 32532087
Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy
Nutrients · 2020
PMID 35890318
Immunomodulatory Effect of Hispolon on LPS-Induced RAW264.7 Cells and Mitogen/Alloantigen-Stimulated Spleen Lymphocytes of Mice
Pharmaceutics · 2022