natural remedies · Ingredient
(+)-limacine
Formula: C37H40N2O6 · MW: 608.7350000000004 · Drug-likeness: 0.271
⚗️ Identity
Name
(+)-limacine
Aliases / Synonyms
Fangchinoline; (+)-Fangchinoline; 436-77-1; 7-O-Demethyltetrandrine; Hanfangchin B; NSC 77036; NSC-77036; UNII-953592C3ZB; NSC77036
🧪 Chemistry
Molecular Weight
608.7350
LogP
6.8594
Drug-likeness
0.271
Oral Bioavailability
11.7270
H-Bond Acceptors
8
H-Bond Donors
1
Rotatable Bonds
3
🔗 External References
0
Clinical Trials
0
Meta-Analyses
3
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 35163790
Novel Aurora A Kinase Inhibitor Fangchinoline Enhances Cisplatin-DNA Adducts and Cisplatin Therapeutic Efficacy in OVCAR-3 Ovarian Cancer Cells-Derived Xenograft Model
Int J Mol Sci · 2022
PMID 35700820
Fangchinoline inhibits non-small cell lung cancer metastasis by reversing epithelial-mesenchymal transition and suppressing the cytosolic ROS-related Akt-mTOR signaling pathway
Cancer Lett · 2022
PMID 35867025
Fangchinoline abrogates growth and survival of hepatocellular carcinoma by negative regulation of c-met/HGF and its associated downstream signaling pathways
Phytother Res · 2022