Holistic Remedies · Ingredient
Oleuropein
Formula: C25H32O13 · MW: 540.5180000000005 · Drug-likeness: 0.131
⚗️ Identity
Name
Oleuropein
Aliases / Synonyms
32619-42-4; Oleoeuropein; oleoeuropeine; EINECS 251-129-6; UNII-2O4553545L; OLEUROPEIN [MI]; OLEUROPEIN [VANDF]; OLEUROPEIN [USP-RS]; OLEUROPEIN [WHO-DD]
🧪 Chemistry
Molecular Weight
540.5180
LogP
-0.6342
Drug-likeness
0.131
Oral Bioavailability
4.9530
H-Bond Acceptors
13
H-Bond Donors
6
Rotatable Bonds
9
🔗 External References
3
Clinical Trials
3
Meta-Analyses
10
PubMed References
Top Conditions Studied with Oleuropein
📋 Sample Trials
NCT04328571
Effects of Enzymatic Digestion and Probiotic on Oleuropein Bioavailability
Completed · Healthy Subjects
NCT05217433
Oleuropein and Muscle Energy Metabolism
Completed · Muscular Fatigue
NCT05482373
Adjuvant Treatment in Elderly Patients With Periodontitis Through the Administration of a Supplement Rich in Oleuropein From the Olive Leaf
Recruiting · Periodontitis
📊 Sample Meta-Analyses
CRD42019129083
Association between olive leaf oleuropein and cardiovascular diseases: a systematic review
CRD42021273708
The antioxidant effect of oleuropein consumption on cardiovascular disease in the adult population: a systematic review.
Knowing that cardiovascular diseases are the major cause of death nowadays, it i
CRD42022375615
Olive leaf oleuropein effects in metabolism: a systematic review of randomized controlled trials
Studies that assess specific health conditions will be evaluated. This means stu
📚 Sample References
PMID 28057028
Oleuropein enhances radiation sensitivity of nasopharyngeal carcinoma by downregulating PDRG1 through HIF1α-repressed microRNA-519d
J Exp Clin Cancer Res · 2017
PMID 24486195
Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism
J Mol Cell Cardiol · 2014
PMID 22214867
Preventive and therapeutic effects of oleuropein against carbon tetrachloride-induced liver damage in mice
Pharmacol Res · 2012
PMID 21145829
Oleuropein attenuates hepatic steatosis induced by high-fat diet in mice
J Hepatol · 2011
PMID 32598912
Oleuropein promotes hippocampal LTP via intracellular calcium mobilization and Ca2+-permeable AMPA receptor surface recruitment
Neuropharmacology · 2020
PMID 33582227
Acute administration of the olive constituent, oleuropein, combined with ischemic postconditioning increases myocardial protection by modulating oxidative defense
Free Radic Biol Med · 2021
🏥 Linked Health Topics 1 · matched via study conditions