natural remedies · Ingredient
Salidroside
Formula: C14H20O7 · MW: 300.307 · Drug-likeness: 0.461
⚗️ Identity
Name
Salidroside
Aliases / Synonyms
10338-51-9; Rhodioloside; Rhodosin; sallidroside; salidroside, (-)-; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol; Glucopyranoside, p-hydroxyphenethyl; Tyrosol glucoside; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenethoxy)tetrahydro-2H-pyran-3,4,5-triol
🧪 Chemistry
Molecular Weight
300.3070
LogP
-1.2488
Drug-likeness
0.461
Oral Bioavailability
7.0100
H-Bond Acceptors
7
H-Bond Donors
5
Rotatable Bonds
5
🔗 External References
0
Clinical Trials
0
Meta-Analyses
12
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 31735552
Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-α-driven inflammation and ER stress
EBioMedicine · 2019
PMID 31251107
Salidroside alleviates high-glucose-induced injury in retinal pigment epithelial cell line ARPE-19 by down-regulation of miR-138
RNA Biol · 2019
PMID 30624028
Salidroside-Pretreated Mesenchymal Stem Cells Enhance Diabetic Wound Healing by Promoting Paracrine Function and Survival of Mesenchymal Stem Cells Under Hyperglycemia
Stem Cells Transl Med · 2019
PMID 30396856
Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathway
EBioMedicine · 2018
PMID 29723606
Salidroside mediated stabilization of Bcl -xL prevents mitophagy in CA3 hippocampal neurons during hypoxia
Neurobiol Dis · 2018
PMID 27933142
Salidroside reduces tau hyperphosphorylation via up-regulating GSK-3β phosphorylation in a tau transgenic Drosophila model of Alzheimer's disease
Transl Neurodegener · 2016