Holistic Remedies · Ingredient
Sinapic acid
Formula: C11H12O5 · MW: 224.212 · Drug-likeness: 0.758
⚗️ Identity
Name
Sinapic acid
Aliases / Synonyms
Sinapinic acid; 530-59-6; 3,5-Dimethoxy-4-hydroxycinnamic acid; trans-sinapic acid; 7362-37-0; SINAPINATE; (E)-Sinapic acid; 4-Hydroxy-3,5-dimethoxycinnamic acid; Sinapate
🧪 Chemistry
Molecular Weight
224.2120
LogP
1.5072
Drug-likeness
0.758
Oral Bioavailability
64.1460
H-Bond Acceptors
4
H-Bond Donors
2
Rotatable Bonds
4
🔗 External References
0
Clinical Trials
0
Meta-Analyses
9
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32760968
Variability of sinapic acid derivatives during germination and their contribution to antioxidant and anti-inflammatory effects of broccoli sprouts on human plasma and human peripheral blood mononuclear cells
Food Funct · 2020
PMID 32792955
Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways
Front Pharmacol · 2020
PMID 33233476
Sinapic Acid Inhibits Cardiac Hypertrophy via Activation of Mitochondrial Sirt3/SOD2 Signaling in Neonatal Rat Cardiomyocytes
Antioxidants (Basel) · 2020
PMID 33312339
Ameliorative Effect of Sinapic Acid on Dextran Sodium Sulfate- (DSS-) Induced Ulcerative Colitis in Kunming (KM) Mice
Oxid Med Cell Longev · 2020
PMID 33642831
Sinapic acid ameliorates D-galactosamine/lipopolysaccharide-induced fulminant hepatitis in rats: Role of nuclear factor erythroid-related factor 2/heme oxygenase-1 pathways
World J Gastroenterol · 2021
PMID 33716749
Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role
Front Pharmacol · 2021