Holistic Remedies · Ingredient
Tangeretin
Formula: C20H20O7 · MW: 372.3730000000001 · Drug-likeness: 0.655
⚗️ Identity
Name
Tangeretin
Aliases / Synonyms
481-53-8; Tangeritin; Ponkanetin; Pentamethoxyflavone; 4',5,6,7,8-Pentamethoxyflavone; 5,6,7,8,4'-Pentamethoxyflavone; 4H-1-Benzopyran-4-one, 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-; 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one; 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
🧪 Chemistry
Molecular Weight
372.3730
LogP
3.5030
Drug-likeness
0.655
Oral Bioavailability
21.3750
H-Bond Acceptors
7
Rotatable Bonds
6
🔗 External References
0
Clinical Trials
0
Meta-Analyses
8
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 28958806
Role of tangeretin as a potential bioavailability enhancer for silybin: Pharmacokinetic and pharmacological studies
Pharmacol Res · 2018
PMID 32031202
Tangeretin mitigates l-NAME-induced ventricular dysfunction and remodeling through the AT1R/pERK1/2/pJNK signaling pathway in rats
Food Funct · 2020
PMID 32619557
Synergistic therapy with tangeretin and 5-fluorouracil accelerates the ROS/JNK mediated apoptotic pathway in human colorectal cancer cell
Food Chem Toxicol · 2020
PMID 33202982
Tangeretin Ameliorates Glucose-Induced Podocyte Injury through Blocking Epithelial to Mesenchymal Transition Caused by Oxidative Stress and Hypoxia
Int J Mol Sci · 2020
PMID 34580918
Tangeretin promotes lifespan associated with insulin/insulin-like growth factor-1 signaling pathway and heat resistance in Caenorhabditis elegans
Biofactors · 2021
PMID 35104760
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways
Phytomedicine · 2022