Holistic Remedies · Ingredient
Withaferin a
Formula: C28H38O6 · MW: 470.6060000000002 · Drug-likeness: 0.485
⚗️ Identity
Name
Withaferin a
Aliases / Synonyms
5119-48-2; Withaferine A; NSC 273757; WITHAFERIN DERIV JPR, IOWA U. COMPOUND; CHEBI:69120; NSC-101088; NSC101088; L6DO3QW4K5; CHEMBL517080
🧪 Chemistry
Molecular Weight
470.6060
LogP
3.3529
Drug-likeness
0.485
H-Bond Acceptors
6
H-Bond Donors
2
Rotatable Bonds
3
🔗 External References
0
Clinical Trials
0
Meta-Analyses
21
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 31642559
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis
Cell Prolif · 2020
PMID 31319622
Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer
Cancers (Basel) · 2019
PMID 30696468
Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
J Hematol Oncol · 2019
PMID 29939160
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
J Clin Invest · 2018
PMID 28919038
Covalent Ligand Discovery against Druggable Hotspots Targeted by Anti-cancer Natural Products
Cell Chem Biol · 2017
PMID 28425984
Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences
Cell Death Dis · 2017