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Each record is a registered study, a systematic-review registration or a publication. A registered or ongoing study is not a finding, and animal or cell research does not show an effect in people. The same study can appear under more than one subject, so the number of records is not a count of independent studies. You can also search an exact DOI, PubMed ID, NCT or CRD number. How to read these records.
52 study records (showing up to 30 per record type)
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Registered trial NCT05885906 Phase 3 Not completed: Active Not RecruitingAloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 DiabeticsCondition or outcome area: Xerostomia2023-07-24 · Subject: She Xiang Cao; 麝香草; Thyme; Thymus Vulgaris · open the herb record · ClinicalTrials.gov
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Registered trial NCT06170333 Phase 4 Completed (results not assessed here)8% Sulphur-Aloe Vera Soap as an Adjuvant Treatment for Pityriasis VersicolorCondition or outcome area: Pityriasis Versicolor
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Registered trial NCT05885906 Phase 3 Not completed: Active Not RecruitingAloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 DiabeticsCondition or outcome area: Xerostomia
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Registered trial NCT06041178 Phase 4 Completed (results not assessed here)Flurbiprofen Versus Aloe Vera Gel in the Treatment of Chronic Periodontitis in Smoking Patients.Condition or outcome area: Periodontitis Chronic Generalized Severe
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Registered trial NCT06170333 Phase 4 Completed (results not assessed here)8% Sulphur-Aloe Vera Soap as an Adjuvant Treatment for Pityriasis VersicolorCondition or outcome area: Pityriasis Versicolor2023-08-25 · Subject: Liu Huang; 硫黄; Sulfur; Sulphur;Sulfur · open the herb record · ClinicalTrials.gov
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Registered trial NCT05369234 Phase 3 Not completed: RecruitingEffects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and EsophagitisCondition or outcome area: Oral Cavity Cancer|Head and Neck Cancers - Tonsils|Esophageal Cancer|Laryngeal Cancer|Oropharynx Cancer|Mediastinal Cancer|Chest Wall Tumor|Radiation Mucositis
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Registered trial NCT05369234 Phase 3 Not completed: RecruitingEffects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and EsophagitisCondition or outcome area: Oral Cavity Cancer|Head and Neck Cancers - Tonsils|Esophageal Cancer|Laryngeal Cancer|Oropharynx Cancer|Mediastinal Cancer|Chest Wall Tumor|Radiation Mucositis2022-01-20 · Subject: Hao Wang Jiao Lu Hui; 好望角芦荟; Cape Of Good Hope Aloe Dried Juice; Aloe Ferox · open the herb record · ClinicalTrials.gov
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Registered trial NCT05327049 Completed (results not assessed here)Evaluation of the Remineralizing Effect of Aloe Vera Versus Diode Laser for Management of Deep Carious Lesions.Condition or outcome area: Deep Caries
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Registered trial NCT05327049 Completed (results not assessed here)Evaluation of the Remineralizing Effect of Aloe Vera Versus Diode Laser for Management of Deep Carious Lesions.Condition or outcome area: Deep Caries2021-02-01 · Subject: Hao Wang Jiao Lu Hui; 好望角芦荟; Cape Of Good Hope Aloe Dried Juice; Aloe Ferox · open the herb record · ClinicalTrials.gov
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Registered trial NCT05578638 Not completed: RecruitingComparing Aloe Vera Gel and Rosemary Oil in Pressure Injury PreventionCondition or outcome area: Pressure Injury2022-11-01 · Subject: Mi Die Xiang; 迷迭香; Rosemary; Herba Rosmarini Officinalis · open the herb record · ClinicalTrials.gov
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Registered trial NCT05578638 Not completed: RecruitingComparing Aloe Vera Gel and Rosemary Oil in Pressure Injury PreventionCondition or outcome area: Pressure Injury2022-11-01 · Subject: Hao Wang Jiao Lu Hui; 好望角芦荟; Cape Of Good Hope Aloe Dried Juice; Aloe Ferox · open the herb record · ClinicalTrials.gov
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Registered trial NCT03204097 Phase 2 / Phase 3 Completed (results not assessed here)Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic PeriodontitisCondition or outcome area: Chronic Periodontitis
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Registered trial NCT04942470 Completed (results not assessed here)Effect of Aloe Vera and Propolis on Wound Healing in Pressure InjuriesCondition or outcome area: Pressure Ulcer
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Registered trial NCT03204071 Phase 2 / Phase 3 Completed (results not assessed here)Locally Delivered Metformin and Aloe Vera for Treatment of Intrabody Defects in Chronic PeriodontitisCondition or outcome area: Chronic Periodontitis
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Registered trial NCT04964167 Phase 4 Completed (results not assessed here)Indocyanine-green Mediated Photosensitizer VS Aloe Vera Gel: Adjunct Therapy to Scaling and Root Planing in Patients With Chronic PeriodontitisCondition or outcome area: Periodontitis|Periodontal Inflammation
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Registered trial NCT00876642 Phase 3 Completed (results not assessed here)Trial Comparing Best Supportive Care to Aloe Vera GelCondition or outcome area: Radiation Dermatitis
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Registered trial NCT04753775 Completed (results not assessed here)RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF ENEMA ALOE VERA GEL IN ACTIVE ULCERATIVE PROCTOSIGMOIDITIS.Condition or outcome area: Aloe Vera Gel, Proctosigmoiditis, Remission, Trial, Ulcerative Colitis (UC)
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Registered trial NCT04615585 Completed (results not assessed here)Evaluation of Local Delivery of Aloe Vera Gel as an Adjunct to Non-surgical Treatment in Patients With Chronic PeriodontitisCondition or outcome area: Chronic Periodontitis
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Registered trial NCT02560870 Phase 2 / Phase 3 Completed (results not assessed here)Compare the Efficacy of Aloe Vera Mouthwash With Non- Alcoholic Chlorhexidine Mouthwash on Periodontal DiseasesCondition or outcome area: Periodontal Diseases
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Registered trial NCT02437747 Phase 4 Completed (results not assessed here)Locally Delivered Aloe Vera Gel in the Treatment of Chronic Periodontitis Patients With Diabetes MellitusCondition or outcome area: Diabetes Mellitus|Chronic Periodontitis
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Registered trial NCT01400048 Completed (results not assessed here)Aloe Vera in Irritable Bowel SyndromeCondition or outcome area: Irritable Bowel Syndrome
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Registered trial NCT02386020 Phase 2 / Phase 3 Completed (results not assessed here)Aloe Vera in Chronic Periodontitis With Type 2 Diabetes MellitusCondition or outcome area: Chronic Periodontitis
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Registered trial NCT02235532 Completed (results not assessed here)Effects of Aloe Vera Toothpaste on Periodontal ParametersCondition or outcome area: Gingivitis
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Registered trial NCT02462993 Phase 2 / Phase 3 Completed (results not assessed here)Local Drug Delivery of Aloe Vera Gel in Chronic PeriodontitisCondition or outcome area: Periodontitis
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Registered trial NCT04662385 Phase 2 Completed (results not assessed here)The Effect of Toothpaste Containing Aloe Vera on GingivitisCondition or outcome area: Generalized Gingivitis
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Registered trial NCT04009616 Completed (results not assessed here)Effect of Aloe Vera Mouthwashes on the Oral Health of ChildrenCondition or outcome area: Oral Health
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Registered trial NCT03633292 Phase 4 Completed (results not assessed here)Aloe Vera and Chlorhexidine Against Traumatic Oral UlcersCondition or outcome area: Oral Ulcer
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Registered trial NCT03934762 Completed (results not assessed here)Aloe Vera Ointment Application and Skeletal Muscle RecoveryCondition or outcome area: Skeletal Muscle Damage|Exercise-induced Aseptic Inflammation|Performance
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Registered trial NCT04719247 Completed (results not assessed here)Clinical and Radiographic Evaluation of Turmeric, Thymus Vulgaris, Nigella Sativa and Aloe Vera as Pulpotomy Medicaments in Primary TeethCondition or outcome area: Pulpitis - Irreversible2019-11-01 · Subject: Zai Pei Hei Zhong Cao; 栽培黑种草; Cultivated Fennelflower; Nigella Sativa · open the herb record · ClinicalTrials.gov
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Registered trial NCT04719247 Completed (results not assessed here)Clinical and Radiographic Evaluation of Turmeric, Thymus Vulgaris, Nigella Sativa and Aloe Vera as Pulpotomy Medicaments in Primary TeethCondition or outcome area: Pulpitis - Irreversible2019-11-01 · Subject: Jiang Huang; 姜黄; Turmeric;Rhizome Of Common Turmeric; Rhizoma Curcumae Longae;Curcumae Longae Rhizoma · open the herb record · ClinicalTrials.gov
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Systematic review registration CRD42023472125 Registered protocol, no results here: Review OngoingAloe vera in the prevention and treatment of mucositis: systematic review with meta-analysisCondition or outcome area: Stomatitis or oral mucositis is known as a general and painful complication of several diseases and their treatments. This is an injury that involves oral soft tissues, especially non-keratinized ones. Mucositis can trigger a chain of risky events: pain, poor oral intake, weight loss, treatment interruptions and, ultimately, increased cure rates. Aloe vera has been widely used to treat various situations. Promising results have been reported by scientists regarding the preventive effects of aloe
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Systematic review registration CRD42023412335 Registered protocol, no results here: Review OngoingEfficacy of Oral Aloe Vera Supplementation on Skin wrinkles, Hydration, Elasticity, Transepidermal Water Loss and Collagen Score: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsCondition or outcome area: Wrinkles are major features of aging; and skin hydration, skin elasticity, transepidermal water loss (TEWL), and collagen score are some parameters used in measuring the skin’s resilience to wrinkles. Orally administered aloe vera supplements have shown promise in alleviating some of these skin aging parameters. To determine the effects of oral aloe vera supplements on skin wrinkles, hydration, elasticity, TEWL, and collagen score compared with placebo or no treatment.
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Systematic review registration CRD42023407225 Registered protocol, no results here: Review OngoingThe effectiveness of lanolin and aloe vera on sore nipples in lactating women: a systematic review and meta-analysisCondition or outcome area: This study will prove that lanolin and aloe vera reduce pain, trauma, fissure and irritation of sores nipples in lactating women. Therefore this study will carried out to evaluate the effectiveness of lanolin and aloe vera on sore nipples among lactating women.
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Systematic review registration CRD42022367047 Registered protocol, no results here: Review OngoingEfficacy of Aloe Vera gel, spirulina tablet and topical curcumin in management of oral submucous fibrosis: A Randomized Controlled TrialCondition or outcome area: Oral Submucous Fibrosis (OSMF)2022-10-24 · Subject: Curcumin; 458-37-7; Diferuloylmethane; Natural yellow 3; Kacha haldi; Indian saffron; Curcuma; Gelbwurz; Haldar; Curcumin I · open the ingredient record
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Systematic review registration CRD42018097427 Registered protocol, no results here: Review OngoingThe efficacy of aloe vera gel and cream to prevent and to treat radiodermatitis in women with breast cancer: a systematic reviewCondition or outcome area: Radiodermatitis associated with the irradiation of breast tissue due to cancer.
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Systematic review registration CRD42019127098 Registered protocol, no results here: Review OngoingAloe vera in treatment of acute wounds: a systematic review and meta-analysisCondition or outcome area: Acute wound, for example lacerations, surgical incisions and burns.
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Systematic review registration CRD42020152522 Registered protocol, no results here: Review Completed publishedAloe vera and health outcomes: an umbrella review of systematic reviews and meta-analysesCondition or outcome area: Health outcomes that seem to be related with Aloe vera obtaining will be studied in this review.
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Systematic review registration CRD42020164233 Registered protocol, no results here: Review OngoingSoft tissue changes on administration of Aloe vera in treatment of periodontal diseases: A systematic reviewCondition or outcome area: Periodontal disease is a multifactorial infection causing the destruction of the supporting structure of the teeth. In humans the prevalence of the disease is 10-60%.
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Systematic review registration CRD42020201315 Registered protocol, no results here: Review OngoingClinical Effectiveness of Aloe Vera as an adjunct to non-surgical periodontal therapy in patients with chronic periodontitis - A systematic review and meta-analysisCondition or outcome area: Periodontitis is a common chronic inflammatory disease that leads to destruction of the supporting tissues of the teeth. The onset and progression of this disease is initiated by microorganisms, and results when the balance between periodontal pathogens and the host immune response is disturbed. It can lead to the formation of a pathological periodontal pocket, root exposure due to gingival recession, and increased tooth mobility. Further progression of the disease may lead to tooth migration, c
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Systematic review registration CRD42020210630 Registered protocol, no results here: Review OngoingEfficacy of Aloe Vera in the management of oral precancerous lesions compared to other antioxidants treatment- A Systematic ReviewCondition or outcome area: Oral precancerous lesions like OSMF, Lichen Planus & Leukoplakia are predominantly prevalent in Indian population due to the consumption of tobacco, areca nut, and its various products. These precancerous lesions mostly have a tendency to transform into malignant conditions. OSMF is a pre-cancerous condition in which there is excessive production of collagen and inflammation of the oral mucosa along with burning sensation. Leukoplakia is a premalignant lesion which is a white non scrapable p
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Systematic review registration CRD42022314790 Registered protocol, no results here: Review OngoingAntimicrobial efficacy of Aloe Vera as compared to other intra-canal medication against enterococcus faecalis microbe: A systemic review and Meta- AnalysisCondition or outcome area: Enterococcus faecalis is in category of persistent microbes. This persistent microbe is one of the reasons behind endodontic treatment failure. The effect of anti-microbial activity of Aloe Vera will be reviewed on enterococcus faecalis bacterial count, Zone of inhibition, Mean optical density, Minimum inhibitory concentration, and Minimum bactericidal concentration.
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Systematic review registration CRD42022316783 Registered protocol, no results here: Review OngoingEffects of Aloe vera in the treatment of oral ulcers: a meta-analysis of randomized controlled trialsCondition or outcome area: Oral ulcer is a disease of oral mucosa described as a loss of mucous substance of the mouth showing local excavation of the surface, resulting from slough of inflammatory necrotic tissue. Various of oral ulcer annoyed people’s life, such as recurrent aphthous stomatitis, traumatic oral ulceration, mucositis caused by radiation.
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Systematic review registration CRD42022318695 Registered protocol, no results here: Review OngoingTOPICAL EFFECTS OF ALOE VERA IN WOUND HEALING ON DIABETIC FOOT ULCERS: A SYSTEMATIC REVIEWCondition or outcome area: Topical effect of aloe vera in wound healing on diabetic foot ulcers
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Systematic review registration CRD42022328901 Registered protocol, no results here: Review OngoingClinical Effectiveness of Aloe Vera as an Alternative Medicament in Vital Pulp Therapy - A systematic reviewCondition or outcome area: Vital pulp therapy
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Systematic review registration CRD42020150637 Registered protocol, no results here: Review OngoingEfficacy of Aloe vera in the management of oral mucositis secondary to chemotherapy and/or radiotherapy: a systematic reviewCondition or outcome area: Oral mucositis is a common side effect in patients with head and neck cancers or hematological malignancies who are receiving chemotherapy and/or radiotherapy, and is a condition which interferes with patient nutrition, and overall quality of life.
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Systematic review registration CRD42021276418 Registered protocol, no results here: Review OngoingClinical effect of Aloe vera as supplement to periodontal therapy: a systematic review and meta-analysisCondition or outcome area: Periodontitis is an infectious disease resulting from complex host pathogenic interaction between virulent bacteria and the host response, which leads to progressive tissue destruction, loss of periodontal attachment, and eventually tooth loss. Nonsurgical periodontal therapy (NSPT) through scaling and root planing (SRP) for bacterial biofilms is a fundamental step in the treatment of periodontal disease. However, this step is insufficient to keep the subgingival microbiota under control and to
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Systematic review registration CRD42022335188 Registered protocol, no results here: Review OngoingAloe vera for prevention of radiation-induced dermatitis: a systematic review and cumulative analysis of randomized controlled trialsCondition or outcome area: Radiation-induced dermatitis.
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Systematic review registration CRD42018088663 Registered protocol, no results here: Review OngoingThe effect of aloe vera mouth-rinse versus chlorhexidine on plaque and gingivitis. A systematic review and meta-analysisCondition or outcome area: Gingivitis and plaque.
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Systematic review registration CRD42018088527 Registered protocol, no results here: Review Completed publishedAloe vera in management of oral submucous fibrosis: a systematic reviewCondition or outcome area: Oral submucous fibrosis, a precancerous oral lesion.
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Systematic review registration CRD42018082663 Registered protocol, no results here: Review OngoingAmong adults diagnosed with irritable bowel syndrome and inflammatory bowel disease, is the consumption of Aloe Vera, compared to placebo associated with improved health outcomes? Rationale and protocol for a systematic reviewCondition or outcome area: This review seeks to summarize the evidence from existing studies on the contribution of Aloe Vera towards improved health outcomes in patients diagnosed with Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD). For studies focusing on IBS, improvement in quality of life and improvement in overall symptoms will be used as the primary outcome. For studies focusing on IBD, improvement in quality of life and induction of remission will be the main primary outcomes. The outcome meas
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Systematic review registration CRD42015029872 Registered protocol, no results here: Review OngoingThe efficacy of Aloe vera for blood glucose and lipid profile control: a systematic review and meta-analysisCondition or outcome area: Blood glucose control including fasting plasma glucose (FPG), HbA1C and postprandial glucose (PPG) levels and homeostasis model assessment of insulin resistance (HOMA-IR) of participants who use Aloe vera products. Lipid profile control including LDL, HDL, triglyceride (TG) and total cholesterol (TC) levels of participants who use Aloe vera products. Blood pressure including systolic blood pressure (SBP) and diastolic blood pressure (DBP) of participants who use Aloe vera products. Body weight,
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Systematic review registration CRD42015015821 Registered protocol, no results here: Review OngoingUse of aloe vera for treatment of burning mouth syndrome and oral lichen planusCondition or outcome area: Burning mouth syndrome is characterized by intense pain and discomfort in the oral cavity, and often does not have a discernible cause. It is a common condition that primarily affects menopausal women, and affects 15% of the adult population. It is sometimes found to be related to infections, vitamin deficiencies, and irritants such as ill-fitting dentures and allergies, as well as concomitant neuropathies or psychiatric conditions. Notably, these patients do not have any objective findings in t