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Each record is a registered study, a systematic-review registration or a publication. A registered or ongoing study is not a finding, and animal or cell research does not show an effect in people. The same study can appear under more than one subject, so the number of records is not a count of independent studies. You can also search an exact DOI, PubMed ID, NCT or CRD number. How to read these records.

15 study records (showing up to 30 per record type)

• Registered trial NCT05258513 Completed (results not assessed here)
  The Effects of Geranylgeraniol (GG) Sourced From Annatto on Sexual Health
  Condition or outcome area: Sexual Health|Libido
  2022-02-06 · Subject: Tetraprenol; Geranylgeraniol; gernaylgeraniol; 2,6,10,14-Hexadecatetraen-1-ol, 3,7,11,15-tetramethyl-, (2E,6E,10E)- (9CI); NCGC00096069-01; NCGC00096069-02; trans-Geranylgeraniol; (E,E,E)-Geranylgeraniol; trans,trans,trans-Geranylgeraniol; all trans-3,7,11-15-Tetramethyl-2,6,10,14-hexadecatetraen-1-ol · open the ingredient record · ClinicalTrials.gov
• Registered trial NCT05258513 Completed (results not assessed here)
  The Effects of Geranylgeraniol (GG) Sourced From Annatto on Sexual Health
  Condition or outcome area: Sexual Health|Libido
  2022-02-06 · Subject: Geranylgeraniol; (2E,6E,10Z)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol · open the ingredient record · ClinicalTrials.gov
• Publication PMID 34638882 Research model: Cell Experiment
  Geranylgeraniol Inhibits Lipopolysaccharide-Induced Inflammation in Mouse-Derived MG6 Microglial Cells via NF-κB Signaling Modulation
  Int J Mol Sci · 2021 · Subject: Tetraprenol; Geranylgeraniol; 24034-73-9; Geranyl geraniol; (2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol; (E,E,E)-Geranylgeraniol; trans-Geranylgeraniol; 7614-21-3; (E,E,E)-Geranylgeranyl alcohol; Geranylgeranyl alcohol · open the ingredient record · DOI 10.3390/ijms221910543
• Publication PMID 36432506 Research model: Cell Experiment
  Anti-Inflammatory Activity of Geraniol Isolated from Lemon Grass on Ox-LDL-Stimulated Endothelial Cells by Upregulation of Heme Oxygenase-1 via PI3K/Akt and Nrf-2 Signaling Pathways
  Condition or outcome area: chronic inflammatory disorder; Hypertension; atherosclerosis; cardiovascular disease
  Nutrients · 2022 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.3390/nu14224817
• Publication PMID 36304965 Research model: Animal Experiment
  Amelioration of Age-Related Multiple Neuronal Impairments and Inflammation in High-Fat Diet-Fed Rats: The Prospective Multitargets of Geraniol
  Condition or outcome area: Neuroinflammation; neuronal impairments; neuroinflammation
  Oxid Med Cell Longev · 2022 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.1155/2022/4812993
• Publication PMID 36121588 Research model: Animal Experiment
  Geraniol accelerates the gastric healing, minimizes ulcers recurrence, and reduces anxiolytic-like behavior in ulcerated rodents by oral or inhaled route
  Condition or outcome area: ulcer; ulcers; anxiety; gastric ulcers
  Inflammopharmacology · 2022 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.1007/s10787-022-01068-x
• Publication PMID 36009287 Research model: Animal Experiment
  Renal Ischemia/Reperfusion Mitigation via Geraniol: The Role of Nrf-2/HO-1/NQO-1 and TLR2,4/MYD88/NFκB Pathway
  Condition or outcome area: Renal ischemia/reperfusion injury; Renal I/R; renal I/R injury
  Antioxidants (Basel) · 2022 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.3390/antiox11081568
• Publication PMID 35932440 Research model: Cell Experiment
  New insights into geraniol's antihemolytic, anti-inflammatory, antioxidant, and anticoagulant potentials using a combined biological and in silico screening strategy
  Condition or outcome area: inflammation
  Inflammopharmacology · 2022 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.1007/s10787-022-01039-2
• Publication PMID 35144136 Research model: Animal Experiment
  Geraniol enhances inhibitory inputs to the paraventricular thalamic nucleus and induces sedation in mice
  Condition or outcome area: insomnia; epilepsy
  Phytomedicine · 2022 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.1016/j.phymed.2022.153965
• Publication PMID 34968469 Research model: Animal Experiment
  Geraniol protects against cyclosporine A-induced renal injury in rats: Role of Wnt/β-catenin and PPARγ signaling pathways
  Condition or outcome area: renal injury; inflammation; acute and chronic kidney disease; nephrotoxicity; fibrosis
  Life Sci · 2022 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.1016/j.lfs.2021.120259
• Publication PMID 34343525 Research model: Animal Experiment
  Geraniol isolated from lemon grass to mitigate doxorubicin-induced cardiotoxicity through Nrf2 and NF-κB signaling
  Condition or outcome area: doxorubicin-induced cardiotoxicity; cardiotoxicity; tumor
  Chem Biol Interact · 2021 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.1016/j.cbi.2021.109599
• Publication PMID 33826182 Research model: Cell Experiment
  Geraniol exerts its antiproliferative action by modulating molecular targets in lung and skin carcinoma cells
  Condition or outcome area: lung and skin cancer; tumor; Ehrlich Ascites Carcinoma
  Phytother Res · 2021 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.1002/ptr.7094
• Publication PMID 33053761 Research model: Animal Experiment
  Protective Effect of Geraniol on Oxidative, Inflammatory and Apoptotic Alterations in Isoproterenol-Induced Cardiotoxicity: Role of the Keap1/Nrf2/HO-1 and PI3K/Akt/mTOR Pathways
  Condition or outcome area: Myocardial infarction; myocardial necrosis
  Antioxidants (Basel) · 2020 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.3390/antiox9100977
• Publication PMID 32171873 Research model: Animal Experiment
  Geraniol protects against cyclophosphamide-induced hepatotoxicity in rats: Possible role of MAPK and PPAR-γ signaling pathways
  Condition or outcome area: hepatotoxicity; CP-induced hepatotoxicity
  Food Chem Toxicol · 2020 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.1016/j.fct.2020.111251
• Publication PMID 32119866 Research model: Cell Experiment
  Induction of oxidative stress as a possible mechanism by which geraniol affects the proliferation of human A549 and HepG2 tumor cells
  Condition or outcome area: malignant tumors; tumor
  Chem Biol Interact · 2020 · Subject: Geraniol; 106-24-1; Geranyl alcohol; Lemonol; trans-Geraniol; (E)-3,7-Dimethylocta-2,6-dien-1-ol; (E)-Geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol; (E)-Nerol; trans-3,7-Dimethyl-2,6-octadien-1-ol · open the ingredient record · DOI 10.1016/j.cbi.2020.109029