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Each record is a registered study, a systematic-review registration or a publication. A registered or ongoing study is not a finding, and animal or cell research does not show an effect in people. The same study can appear under more than one subject, so the number of records is not a count of independent studies. You can also search an exact DOI, PubMed ID, NCT or CRD number. How to read these records.
64 study records (showing up to 30 per record type)
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Registered trial NCT05885906 Phase 3 Not completed: Active Not RecruitingAloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 DiabeticsCondition or outcome area: Xerostomia2023-07-24 · Subject: She Xiang Cao; 麝香草; Thyme; Thymus Vulgaris · open the herb record · ClinicalTrials.gov
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Registered trial NCT05859711 Phase 4 Completed (results not assessed here)Effectiveness of Thyme Honey in Management of Xerostomia in Post Radiation Cancer PatientsCondition or outcome area: Head and Neck Cancer Patients2021-02-20 · Subject: She Xiang Cao; 麝香草; Thyme; Thymus Vulgaris · open the herb record · ClinicalTrials.gov
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Registered trial NCT06129097 Completed (results not assessed here)Thyme Honey Mouthwash in Management of Periodontitis in Renal PatientsCondition or outcome area: Periodontal Diseases|Periodontal Pocket|Periodontal Attachment Loss|Periodontal Inflammation2024-01-01 · Subject: She Xiang Cao; 麝香草; Thyme; Thymus Vulgaris · open the herb record · ClinicalTrials.gov
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Registered trial NCT05885906 Phase 3 Not completed: Active Not RecruitingAloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 DiabeticsCondition or outcome area: Xerostomia
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Registered trial NCT05859711 Phase 4 Completed (results not assessed here)Effectiveness of Thyme Honey in Management of Xerostomia in Post Radiation Cancer PatientsCondition or outcome area: Head and Neck Cancer Patients
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Registered trial NCT06129097 Completed (results not assessed here)Thyme Honey Mouthwash in Management of Periodontitis in Renal PatientsCondition or outcome area: Periodontal Diseases|Periodontal Pocket|Periodontal Attachment Loss|Periodontal Inflammation
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Registered trial NCT05756842 Not completed: Active Not RecruitingHoney Consumption, Oxidative Stress and HealthCondition or outcome area: Oxidative Stress
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Registered trial NCT05258955 Phase 1 Completed (results not assessed here)Title: Comparison of Anti-plaque Efficacy of Natural Honey With Chlorhexidine Mouthwash: A Randomized Controlled TrialCondition or outcome area: Dental Plaque2020-06-03 · Subject: 4- Hexyl Alcohol Acetate; Chlorhexidine · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT05568563 Completed (results not assessed here)Comparison of Effectiveness of Pre-cooling With Ethyl Chloride Versus HoneyCondition or outcome area: Irreversible Pulpitis
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Registered trial NCT05427799 Not completed: RecruitingThe Influence of Daily Honey Consumption on IR in Obese Women With IRCondition or outcome area: Insulin Resistance
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Registered trial NCT04292314 Phase 2 / Phase 3 Completed (results not assessed here)Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major ThalassemiaCondition or outcome area: Iron Overload|Oxidative Stress|Thalassemia Major2019-11-01 · Subject: Zai Pei Hei Zhong Cao; 栽培黑种草; Cultivated Fennelflower; Nigella Sativa · open the herb record · ClinicalTrials.gov
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Registered trial NCT04880148 Not completed: UnknownThe Effectiveness of a Thyme and Honey Spray for Oral ToxicitiesCondition or outcome area: Cancer of the Head and Neck|Xerostomia|Oral Mucositis|Radiation Toxicity2021-11-03 · Subject: She Xiang Cao; 麝香草; Thyme; Thymus Vulgaris · open the herb record · ClinicalTrials.gov
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Registered trial NCT05231096 Completed (results not assessed here)Comparison of the Effect of Gingival Massage of Aloe-vera Gel and Sidr Honey on Chronic PeriodontitisCondition or outcome area: Gingival Massage|Chronic Periodontitis
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Registered trial NCT05231096 Completed (results not assessed here)Comparison of the Effect of Gingival Massage of Aloe-vera Gel and Sidr Honey on Chronic PeriodontitisCondition or outcome area: Gingival Massage|Chronic Periodontitis2019-09-03 · Subject: Hao Wang Jiao Lu Hui; 好望角芦荟; Cape Of Good Hope Aloe Dried Juice; Aloe Ferox · open the herb record · ClinicalTrials.gov
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Registered trial NCT05231096 Completed (results not assessed here)Comparison of the Effect of Gingival Massage of Aloe-vera Gel and Sidr Honey on Chronic PeriodontitisCondition or outcome area: Gingival Massage|Chronic Periodontitis
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Registered trial NCT04848259 Early_Phase 1 Completed (results not assessed here)Effect of Honey and Dexamethason on Extraction HealingCondition or outcome area: Impacted Third Molar Tooth
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Registered trial NCT01371266 Completed (results not assessed here)Glycemic Effects of HoneyCondition or outcome area: Pre-diabetes
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Registered trial NCT02272673 Completed (results not assessed here)The Effects of Honey on Febrile Neutropenia in Children With Acute Lymphoblastic LeukemiaCondition or outcome area: Acute Lymphoblastic Leukemia
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Registered trial NCT01465308 Phase 2 Completed (results not assessed here)The Effect of Honey on Xerostomia and Oral MucositisCondition or outcome area: Head and Neck Cancer
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Registered trial NCT03929224 Phase 4 Completed (results not assessed here)The Use of Medical Grade Honey in the Prevention of Bone Anchored Hearing Aid Associated Skin BreakdownCondition or outcome area: Skin Infection
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Registered trial NCT04347382 Phase 3 Completed (results not assessed here)Honey & Nigella Sativa Trial Against COVID-19Condition or outcome area: Coronavirus Infection|Sars-CoV22020-04-30 · Subject: Zai Pei Hei Zhong Cao; 栽培黑种草; Cultivated Fennelflower; Nigella Sativa · open the herb record · ClinicalTrials.gov
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Registered trial NCT04347382 Phase 3 Completed (results not assessed here)Honey & Nigella Sativa Trial Against COVID-19Condition or outcome area: Coronavirus Infection|Sars-CoV2
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Registered trial NCT03641053 Phase 3 Completed (results not assessed here)Honey Versus Povidone-iodine on Laceration WoundsCondition or outcome area: Laceration Face|Wound Heal|Wounds and Injuries|Laceration Arm|Laceration of Leg
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Registered trial NCT05264428 Not completed: UnknownThe Effect of Honey on Lessening the Withdrawal SymptomsCondition or outcome area: Smoking Cessation|Withdrawal Symptoms
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Registered trial NCT04030884 Completed (results not assessed here)The Effect of Oral Honey and Water Up to Two Hours Before Surgery on Postoperative Nausea and VomitingCondition or outcome area: Postoperative Nausea and Vomiting
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Registered trial NCT01350193 Phase 1 / Phase 2 Completed (results not assessed here)Manuka Honey Irrigation After Sinus SurgeryCondition or outcome area: Sinusitis
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Registered trial NCT03826537 Completed (results not assessed here)A Study of How Tutin and Hyenanchin, Two Toxins Found in Honey, Are Absorbed and Processed by the BodyCondition or outcome area: Tutin Poisoning
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Registered trial NCT04831112 Completed (results not assessed here)Compare Effects of Dressing With Honey and EUSOLCondition or outcome area: Necrotizing Fascitis|Wound Infection
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Registered trial NCT01974414 Phase 1 / Phase 2 Completed (results not assessed here)Cedar Honey in Oral Lichen PlanusCondition or outcome area: Erosive and Atrophic Oral Lichen Planus
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Registered trial NCT04323345 Phase 3 Not completed: UnknownEfficacy of Natural Honey Treatment in Patients With Novel CoronavirusCondition or outcome area: COVID-19
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Systematic review registration CRD42023467041 Registered protocol, no results here: Review OngoingDoes the use of intra-alveolar honey after lower third molar extraction reduce postoperative pain, edema and alveolitis? A systematic reviewCondition or outcome area: Extraction of lower third molars, the most frequently extracted teeth, accounting for 18% of dental extractions.
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Systematic review registration CRD42020207793 Registered protocol, no results here: Review OngoingEffect of Simiao Yong'an Decoction for coronary heart disease:a study protocol for systematic review and meta-analysisCondition or outcome area: Simiao Yong'an decoction is composed of honeysuckle, scrophularia, angelica and liquorice. Many studies have shown that Simiao Yong'an decoction has anti-inflammatory, anti atherosclerotic, regulating lipid metabolism and promoting angiogenesis, which shows that Simiao Yong'an decoction has multi-channel and multi-target effect, and it has practical application value in the prevention and treatment of coronary heart disease. In a clinical studie, Simiao Yong'an decoction was used to treat 120 ca2020-10-11 · Subject: Si Miao Yong An Tang; 四妙勇安汤; Simiao Yongan Decoction; Si Miao Yong An Decoction · open the formula record
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Systematic review registration CRD42022372085 Registered protocol, no results here: Review OngoingEffectiveness of Honey for Cancer-Related Fatigue: A Systematic Review and Meta-AnalysisCondition or outcome area: Fatigue is a common complaint in cancer patients which profoundly affects the quality of life of the patients.The National Comprehensive Cancer Network (NCCN) released the latest version of the Clinical Practice Guideline for cancer-related fatigue(CRF), which was defined as:a painful, sustained, subjective, physical, emotional, or cognitive fatigue that contradicts recent activity, related to the treatment of cancer or cancer itself, impeding daily function.CRF is common both among those who ha
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Systematic review registration CRD42022369577 Registered protocol, no results here: Review Completed not publishedHoney for acute cough in childrenCondition or outcome area: Cough is a common symptom in children. Acute cough is usually caused by acute respiratory tract infection, which is either viral or bacterial. Cough weakens the quality of life and sleeping quality and therefore symptomatic treatment is needed also in children. Previously over the counter medications were used, but these have associated to increased severe adverse event rates and therefore effective alternatives are needed. Honey has had controversary results regarding the symptomatic relief.
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Systematic review registration CRD42022361568 Registered protocol, no results here: Review OngoingThe efficacy of honey on the healing of caesarean wounds.Condition or outcome area: Gynaecology and obstetrics: caesarean wounds after birth via a caesarean section
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Systematic review registration CRD42022358223 Registered protocol, no results here: Review OngoingThe efficacy of honey on the healing of caesarean wounds.
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Systematic review registration CRD42022289694 Registered protocol, no results here: Review Completed not publishedHoney and its impact as antioxidant on reperfusion injury in experimental studies: a systematic review
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Systematic review registration CRD42021273759 Registered protocol, no results here: Review OngoingThe effects of honey consumption on cardio- metabolic risk factors, a systematic review and meta-analysisCondition or outcome area: The effects of honey on at least one cardiometabolic risk factor in adults, as determined from controlled clinical trials
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Systematic review registration CRD42021250658 Registered protocol, no results here: Review OngoingComparing the effect of honey and clotrimazole in treatment of vaginal candidiasisCondition or outcome area: Candida vaginitis is a very common vaginal infection that affects 75% of women at least once in their lifetime and can cause many complications. Considering the adverse effects of chemical therapies and antifungal properties of In cases with high heterogeneity, subgroup analysis was used based on doses received in the intervention, we performed this systematic review to Comparing the effect of honey and clotrimazole in treatment of vaginal candidiasis.
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Systematic review registration CRD42021248773 Registered protocol, no results here: Review OngoingLocal treatment of diabetic foot with honey: a systematic review and meta analysis.Condition or outcome area: Diabetic foot is a disease that seriously endangers human health. Honey has been used as a medicine to treat wounds since ancient times. Some experimental evidence suggests that honey may accelerate wound healing, but the exact mechanism is not clear. As a method of local treatment of diabetic foot, honey still needs to be further explored.
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Systematic review registration CRD42021247110 Registered protocol, no results here: Review Completed publishedEffect of honey on pediatric radio/chemotherapy-induced oral mucositis (R/CIOM): a systematic review and meta-analysisCondition or outcome area: As one of the most frequent complications after radiotherapy or chemotherapy, oral mucositis occurs in a large amount of pediatric patients receiving cancer therapy. However, up to now, only several interventions showed sufficient effectiveness from randomized clinical trials. When it comes to honey, whether it is effective is still in controversy.
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Systematic review registration CRD42021239253 Registered protocol, no results here: Review OngoingEfficacy of honey in improvement of tear film stability in patients with dry eye: A Systematic review and Meta-analysisCondition or outcome area: This review will study about the effectiveness of honey in patients with dry eye disease
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Systematic review registration CRD42020158645 Registered protocol, no results here: Review OngoingHoney as a therapy for burns: A Systematic Review and Meta-AnalysisCondition or outcome area: Honey has a number of properties which make it appropriate as a wound dressing such as antibacterial properties, bactericidal agents and deodorising properties. A small number of clinical case studies have shown its effectiveness in the treatment of a wide range of wounds other than burns. The objective of our study was to review the clinical evidence of the efficacy of honey in burns wound management.
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Systematic review registration CRD42020156128 Registered protocol, no results here: Review OngoingComparison the effects of oral honey consumption on some metabolic parameters in diabetic and non-diabetic adult individuals: a systematic review of clinical trialsCondition or outcome area: The effects of honey on at least one cardiometabolic risk factor in adults, as determined from controlled clinical trials.
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Systematic review registration CRD42020154137 Registered protocol, no results here: Review OngoingThe effect of honey dressing as a treatment for pressure injury: a systematic reviewCondition or outcome area: management of pressure ulcers
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Systematic review registration CRD42020148034 Registered protocol, no results here: Review OngoingHoney in the treatment of pressure ulcers: a systematic reviewCondition or outcome area: Chronic wounds such as pressure ulcers, leg ulcers and diabetic wounds are a common problem among older people, alternative methods to the current time-consuming and costly practices of wound management need to be identified.
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Systematic review registration CRD42020130741 Registered protocol, no results here: Review OngoingEffect of Natural Honey in Lowering Lipid Profile, Systematic Review and Meta-analysis.Condition or outcome area: This study evaluates the available evidence on the effect of honey on lowering lipid profile.
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Systematic review registration CRD42019128480 Registered protocol, no results here: Review Completed publishedThe effect of honey as a treatment for oral conditions: a systematic reviewCondition or outcome area: Honey is a food product recognised for its potential health benefits, primarily due to a combination of its antioxidant and antibacterial properties. A significant body of research has identified the potential use of honey in wound care. In addition, research has also identified the efficacy of honey in the treatment of mouth conditions, such as wounds or ulcers, although to date the evidence in support has not been collated or evaluated in a systematic review. The outcomes of the systematic rev
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Systematic review registration CRD42019123998 Registered protocol, no results here: Review OngoingThe antimicrobial activity of honey in periodontal disease: a systematic reviewCondition or outcome area: Periodontal disease is a polymicromial infectious disease with an inflammatory component leading to the destruction of periodontal tissues. The microbial flora involved in this infection is highly variable, including aerobic and anaerobic bacteria, as well as viruses, parasites and other pathogens.
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Systematic review registration CRD42018117056 Registered protocol, no results here: Review OngoingAssessment in the use of honey compared to conventional management in the treatment of chronic leg ulcers in adultsCondition or outcome area: Chronic leg ulcers in adults; honey dressings; compressive therapy.
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Systematic review registration CRD42018108486 Registered protocol, no results here: Review OngoingThe prophylactic and therapeutic effect of honey in radio-chemotherapy-induced mucositis: a meta-analysis of randomized controlled trialsCondition or outcome area: Cancer patients suffer from mucositis. Treatment or prevention effect of honey in treatment-induced mucositis.
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Systematic review registration CRD42017070873 Registered protocol, no results here: Review OngoingTopical application of honey in the management of chemo/radiotherapy-induced oral mucositis: a systematic review and network meta-analysisCondition or outcome area: Cancer is a major public health problem worldwide and is the second leading cause of death in the United States.Radiotherapy and chemotherapy are still important means of treating cancer, although it may cause serious adverse reactions.Mucositis is an inflammatory response of mucosal epithelial cells to the cytotoxic effects of chemotherapy and radiation therapy, which is a result of imbalance between cell loss and cell proliferation. The main symptom of oral mucositis is severe debilitating ora
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Systematic review registration CRD42017067582 Registered protocol, no results here: Review Completed publishedThe clinical effects of honey in infectious and atopic upper respiratory tract conditions in patients of all agesCondition or outcome area: Clinically and laboratory-diagnosed infectious or atopic upper respiratory tract conditions – e.g. common cold and influenza, allergic rhinitis.
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Systematic review registration CRD42016049741 Registered protocol, no results here: Review OngoingHoney use in asthma: a systematic review and meta-analysisCondition or outcome area: Bronchial asthma is a common disease with high morbidity rates, the control of which may require multiple drugs. These drugs have several side effects that may interfere with quality of life and the compliance of the patients. There is a real need to use natural substances with fewer side effects, and as such, we need to know if honey is useful in controlling asthma or not.
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Systematic review registration CRD42015023580 Registered protocol, no results here: Review OngoingEffect of honey on cardiometabolic risk in humans: systematic review and meta-analysesCondition or outcome area: To assess the effect of oral honey intake on cardiometabolic risk in adults humans. The following areas of cardiometabolic risk will be investigated: (1) lipids, (2) glycemic control, (3) body weight, (4) uric acid, (5) blood pressure, and (6) markers of non-alcoholic fatty liver (NAFL).
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Systematic review registration CRD42021285433 Registered protocol, no results here: Review OngoingHoney and natural agents for Oral Mucositis in Cancer Patients: A Systematic Review with Network Meta-Analysis of Randomized Clinical TrialsCondition or outcome area: Oral mucositis is the most frequent, distressing, clinical side effect of radiotherapy. Natural agents that have many beneficial health properties, including its ability to facilitate healing.
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Systematic review registration CRD42021205806 Registered protocol, no results here: Review OngoingHoney for the treatment of vulvovaginal candidiasisCondition or outcome area: Vulvovaginal candidiasis
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Systematic review registration CRD42020193847 Registered protocol, no results here: Review Completed publishedHoney bee products for the prevention, treatment and/or recovery from COVID-19 and other coronavirus-related respiratory tract infections: a rapid reviewCondition or outcome area: In the context of the COVID-19 pandemic, tho condition being studied in this systematic review is illness caused by viral infections of the upper or lower respiratory tract including, but not limited to, SARS-CoV-2.
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Systematic review registration CRD42022336793 Registered protocol, no results here: Review OngoingEfficiency of apitherapy for the treatment of oral mucositis in cancer patients: a systematic review and meta-analysisCondition or outcome area: Treatment and/or prevention of oral mucositis in cancer patients
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Systematic review registration CRD42015023580 Registered protocol, no results here: Review OngoingEffect of honey on cardiometabolic risk in humans: systematic review and meta-analysesCondition or outcome area: To assess the effect of oral honey intake on cardiometabolic risk in adults humans. The following areas of cardiometabolic risk will be investigated: (1) lipids, (2) glycemic control, (3) body weight, (4) uric acid, (5) blood pressure, and (6) markers of non-alcoholic fatty liver (NAFL).
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Publication PMID 35059326 Research model: Animal ExperimentSupplementation With Chinese Medicinal Plant Extracts From Lonicera hypoglauca and Scutellaria baicalensis Mitigates Colonic Inflammation by Regulating Oxidative Stress and Gut Microbiota in a Colitis Mouse ModelCondition or outcome area: colonic inflammation; chronic inflammatory bowel disease; Lonicera hypoglauca; colitis; bloody diarrhea; Colitis; inflammation in the colonFront Cell Infect Microbiol · 2022 · Subject: Gu Xian Ren Dong; 菰腺忍冬; Glaucousback Honeysuckle; Lonicera Hypoglauca · open the herb record · DOI 10.3389/fcimb.2021.798052
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Publication PMID 35495054 Research model: Animal ExperimentLonicerae Japonicae Flos Extract Promotes Sleep in Sleep-Deprived and Lipopolysaccharide-Challenged MiceCondition or outcome area: sleep disorders; neuro-inflammation; sleep deprivationFront Neurosci · 2022 · Subject: Jin Yin Hua; 金银花; Honeysuckle Flower; Japanese Honeysuckle Flower; Lonicerae Japonicae Flos; Flos Lonicerae Japonicae · open the herb record · DOI 10.3389/fnins.2022.848588
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Publication PMID 32606669 Research model: Animal ExperimentEffect of Lonicerae japonicae Flos Carbonisata-Derived Carbon Dots on Rat Models of Fever and Hypothermia Induced by LipopolysaccharideCondition or outcome area: dysentery; tumor; fever; hypothermia; tumors; carbuncleInt J Nanomedicine · 2020 · Subject: Jin Yin Hua; 金银花; Honeysuckle Flower; Japanese Honeysuckle Flower; Lonicerae Japonicae Flos; Flos Lonicerae Japonicae · open the herb record · DOI 10.2147/IJN.S248467
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Publication PMID 35624893 Research model: Animal ExperimentAnti-Inflammatory, Anti-Apoptotic, and Antioxidant Roles of Honey, Royal Jelly, and Propolis in Suppressing Nephrotoxicity Induced by Doxorubicin in Male Albino RatsCondition or outcome area: nephrotoxicityAntioxidants (Basel) · 2022 · Subject: Feng Ru; 蜂乳; Royal Jelly; Lac Regis Apis · open the herb record · DOI 10.3390/antiox11051029