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Each record is a registered study, a systematic-review registration or a publication. A registered or ongoing study is not a finding, and animal or cell research does not show an effect in people. The same study can appear under more than one subject, so the number of records is not a count of independent studies. You can also search an exact DOI, PubMed ID, NCT or CRD number. How to read these records.

17 study records (showing up to 30 per record type)

• Registered trial NCT04392622 Phase 1 Not completed: Recruiting
  d-Limonene +Radiation +Platinum Based Chemo for Xerostomia Prevention in Locally Advanced Head and Neck Squamous Cell Carcinoma
  Condition or outcome area: Xerostomia
  2021-02-15 · Subject: Hemo-Sol; D-Limonene; (+ )-Limonene; d-limonene; LIMONENE (D); ()-p-Mentha-1,8-diene; BB_NC-0722; D-Limonen; 4betaH-p-mentha-1,8-diene; LMPR01020041 · open the ingredient record · ClinicalTrials.gov
• Registered trial NCT03609853 Phase 1 Completed (results not assessed here)
  Behavioral Pharmacology of THC and D-limonene
  Condition or outcome area: D-limonene and THC Pharmacodynamics
  2019-04-01 · Subject: Hemo-Sol; D-Limonene; (+ )-Limonene; d-limonene; LIMONENE (D); ()-p-Mentha-1,8-diene; BB_NC-0722; D-Limonen; 4betaH-p-mentha-1,8-diene; LMPR01020041 · open the ingredient record · ClinicalTrials.gov
• Registered trial NCT04853082 Early_Phase 1 Completed (results not assessed here)
  Limonene on Regulating Metabolism-related Fatty Liver Disease (MAFLD) and Analysis of TCM Constitution
  Condition or outcome area: Fatty Liver
  2021-02-22 · Subject: Alpha-Limonene; Limonene; d-Terpinolene; (A)limonene; (+)-Dipentene; dl-Limonene; limonen; Goldflush II; p-Mentha-1,8-diene; Dipenten · open the ingredient record · ClinicalTrials.gov
• Registered trial NCT01459172 Phase 1 Completed (results not assessed here)
  Human Breast Tissue Bioavailability of Topically Applied Limonene
  Condition or outcome area: Breast Cancer
  2007-10 · Subject: Alpha-Limonene; Limonene; d-Terpinolene; (A)limonene; (+)-Dipentene; dl-Limonene; limonen; Goldflush II; p-Mentha-1,8-diene; Dipenten · open the ingredient record · ClinicalTrials.gov
• Registered trial NCT05002192 Not completed: Unknown
  A Retrospective, Real-world Study of ELP Used in the Expectorant Treatment of Community-acquired Pneumonia
  Condition or outcome area: Community-acquired Pneumonia
  2020-09-01 · Subject: Alpha-Limonene; Limonene; d-Terpinolene; (A)limonene; (+)-Dipentene; dl-Limonene; limonen; Goldflush II; p-Mentha-1,8-diene; Dipenten · open the ingredient record · ClinicalTrials.gov
• Registered trial NCT05078723 Not completed: Recruiting
  CYP2C19 Variants and Limonene Metabolism
  Condition or outcome area: CYP2C19 Genetic Variants
  2021-10-30 · Subject: Alpha-Limonene; Limonene; d-Terpinolene; (A)limonene; (+)-Dipentene; dl-Limonene; limonen; Goldflush II; p-Mentha-1,8-diene; Dipenten · open the ingredient record · ClinicalTrials.gov
• Registered trial NCT04484467 Completed (results not assessed here)
  Efficacy and Safety of a Food Supplement With Standardized Menthol, Limonene, and Gingerol Content in Patients With Irritable Bowel Syndrome
  Condition or outcome area: Irritable Bowel Syndrome|Irritable Bowel Syndrome With Diarrhea|Irritable Bowel Syndrome With Constipation|Irritable Bowel Syndrome Mixed
  2018-02-09 · Subject: Alpha-Limonene; Limonene; d-Terpinolene; (A)limonene; (+)-Dipentene; dl-Limonene; limonen; Goldflush II; p-Mentha-1,8-diene; Dipenten · open the ingredient record · ClinicalTrials.gov
• Registered trial NCT01046929 Phase 1 Completed (results not assessed here)
  Limonene Study in Women With Breast Cancer
  Condition or outcome area: Breast Cancer
  2009-08 · Subject: Alpha-Limonene; Limonene; d-Terpinolene; (A)limonene; (+)-Dipentene; dl-Limonene; limonen; Goldflush II; p-Mentha-1,8-diene; Dipenten · open the ingredient record · ClinicalTrials.gov
• Systematic review registration CRD42020186357 Registered protocol, no results here: Review Ongoing
  Antitumoral Activity of Limonene: A Systematic Review Emphasizing its Antitumoral Mechanisms
  2020-05-25 · Subject: L-limonen; Limonene, (-)-; (-)-Limonene; 5989-54-8; l-Limonene; (S)-(-)-Limonene; (S)-Limonene; (S)-1-Methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; beta-Limonene; (-)-(4S)-Limonene · open the ingredient record
• Systematic review registration CRD42020168387 Registered protocol, no results here: Review Ongoing
  The relationship between limonene intake and risk of cancer: a systematic review
  2020-02-18 · Subject: L-limonen; Limonene, (-)-; (-)-Limonene; 5989-54-8; l-Limonene; (S)-(-)-Limonene; (S)-Limonene; (S)-1-Methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; beta-Limonene; (-)-(4S)-Limonene · open the ingredient record
• Systematic review registration CRD42018082207 Registered protocol, no results here: Review Ongoing
  Limonene, perillyl alcohol, perillic acid and perillaldehyde as anticancer agents: a systematic review
  Condition or outcome area: Cancer treatment Cancer prevention
  2018-01-04 · Subject: Perillyl alcohol; 536-59-4; Perilla alcohol; Perillol; Isocarveol; p-Mentha-1,8-dien-7-ol; Hydrocumin alcohol; 1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-; Dihydrocuminyl alcohol; Iso-carveol · open the ingredient record
• Systematic review registration CRD42018082207 Registered protocol, no results here: Review Ongoing
  Limonene, perillyl alcohol, perillic acid and perillaldehyde as anticancer agents: a systematic review
  Condition or outcome area: Cancer treatment Cancer prevention
  2018-01-04 · Subject: Perillic acid; 7694-45-3; (-)-perillic acid; Perillicacid; 4-Isopropenylcyclohex-1-enecarboxylic acid; 4-prop-1-en-2-ylcyclohexene-1-carboxylic acid; PKS69DU4ZQ; 4-(1-methylethenyl)-1-cyclohexene-1-carboxylic acid; 1-Cyclohexene-1-carboxylicacid, 4-(1-methylethenyl)-; CHEBI:36999 · open the ingredient record
• Systematic review registration CRD42018082207 Registered protocol, no results here: Review Ongoing
  Limonene, perillyl alcohol, perillic acid and perillaldehyde as anticancer agents: a systematic review
  Condition or outcome area: Cancer treatment Cancer prevention
  2018-01-04 · Subject: Perillaldehyde; Perillyl aldehyde; 2111-75-3; Perilla aldehyde; Perillal; Perillic aldehyde; P-Mentha-1,8-dien-7-al; Dihydrocuminyl aldehyde; 1-Cyclohexene-1-carboxaldehyde, 4-(1-methylethenyl)-; 4-prop-1-en-2-ylcyclohexene-1-carbaldehyde · open the ingredient record
• Systematic review registration CRD42018082207 Registered protocol, no results here: Review Ongoing
  Limonene, perillyl alcohol, perillic acid and perillaldehyde as anticancer agents: a systematic review
  Condition or outcome area: Cancer treatment Cancer prevention
  2018-01-04 · Subject: L-limonen; Limonene, (-)-; (-)-Limonene; 5989-54-8; l-Limonene; (S)-(-)-Limonene; (S)-Limonene; (S)-1-Methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; beta-Limonene; (-)-(4S)-Limonene · open the ingredient record
• Publication PMID 35026511 Research model: Animal Experiment
  Limonene, a citrus monoterpene, non-complexed and complexed with hydroxypropyl-β-cyclodextrin attenuates acute and chronic orofacial nociception in rodents: Evidence for involvement of the PKA and PKC pathway
  Condition or outcome area: chronic pain; mechanical hyperalgesia; Orofacial pain; temporomandibular joint; chronic constriction injury of the infraorbital nerve; orofacial pain; HPβCD; Chronic orofacial pain
  Phytomedicine · 2022 · Subject: Alpha-limonene; Limonene, (+/-)-; LIMONENE; Dipentene; 138-86-3; Cinene; Cajeputene; DL-Limonene; Kautschin; Dipenten · open the ingredient record · DOI 10.1016/j.phymed.2021.153893
• Publication PMID 34207788 Research model: Cell Experiment
  The Antioxidant Activity of Limonene Counteracts Neurotoxicity Triggered byAβ1-42 Oligomers in Primary Cortical Neurons
  Condition or outcome area: neurodegenerative disorders; Alzheimer's disease
  Antioxidants (Basel) · 2021 · Subject: Alpha-limonene; Limonene, (+/-)-; LIMONENE; Dipentene; 138-86-3; Cinene; Cajeputene; DL-Limonene; Kautschin; Dipenten · open the ingredient record · DOI 10.3390/antiox10060937
• Publication PMID 29794221 Research model: Clinical & Animal Experiment
  Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes
  Proc Natl Acad Sci U S A · 2018 · Subject: Hemo-sol; Limonene, (+)-; D-Limonene; 5989-27-5; (+)-Limonene; (R)-(+)-Limonene; (D)-Limonene; (4R)-Limonene; (+)-(4R)-Limonene; (+)-carvene · open the ingredient record · DOI 10.1073/pnas.1802184115