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Each record is a registered study, a systematic-review registration or a publication. A registered or ongoing study is not a finding, and animal or cell research does not show an effect in people. The same study can appear under more than one subject, so the number of records is not a count of independent studies. You can also search an exact DOI, PubMed ID, NCT or CRD number. How to read these records.

8 study records (showing up to 30 per record type)

• Systematic review registration CRD42012003079 Registered protocol, no results here: Review Ongoing
  Effectiveness and safety of Honghua (safflower) extract injection for angina pectoris: a systematic review of randomized controlled trials
  Condition or outcome area: Angina pectoris Ischemic heart disease is a leading cause of death in the Western countries, where it amounts to almost 33% of overall mortality (Braunwald 1992) and the first clinical sign in over half of patients is angina pectoris (Gibbons 1999). Angina pectoris, generally described as a discomfort within or adjacent to the chest, is the most common clinical manifestation of myocardial ischemia caused by imbalance of myocardial blood supply and metabolic demand due to narrowed or blocked athe
  2012-10-10 · Subject: Hong Hua Zhu She Ye; 红花注射液; Hong Hua Injection · open the formula record
• Systematic review registration CRD42022311478 Registered protocol, no results here: Review Ongoing
  Effect of Hydroxyl safflower yellow A in treating diabetic nephropathy: umbrella review
  Condition or outcome area: By relating to high cardiovascular risk and other serious complications, chronic kidney disease (CKD) has become a major health problem. For most CKD patients, the ultimate outcome is an end-stage renal disease (ESRD) and the last treatment is dialysis or kidney transplantation. Type 2 diabetes mellitus, one of the most important risk factors for CKD, has become a threatening problem[1-3]. With the rapid increase in the population with type 2 diabetes mellitus, DN has become a serious problem in
  2022-03-21 · Subject: Safflower yellow a; (2R,3S,4S,4aR,6S,9bS)-3,4,6,9-tetrahydroxy-2-(hydroxymethyl)-8-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,4,4a,9b-tetrahydro-2H-pyrano[3,2-b][1]benzofuran-7-one · open the ingredient record
• Systematic review registration CRD42022323171 Registered protocol, no results here: Review Ongoing
  Comparative effectiveness of vegetable oils on metabolic status in patients with metabolic disorders: a network meta-analysis of randomized controlled clinical trials
  Condition or outcome area: In the 2015-2020 dietary guidelines for Americans, foods rich in unsaturated fatty acid are recommended to replace those containing saturated fatty acid, which aims to reduce the risk of cardiovascular diseases events (CVD) and CVD-related deaths. Metabolic disorders, including waist obesity, hypertension, dyslipidemia and hyperglycemia, are risk factors of CVD. Therefore, for patients with metabolic disorders, a healthy eating pattern is as important as drug therapy. Vegetable oils are one of m
  2022-05-05 · Subject: Hong Hua; 红花; Safflower; Flos Carthami; Carthami Flos · open the herb record
• Publication PMID 36332390 Research model: Animal Experiment
  Carthami flos extract against carbon tetrachloride-induced liver fibrosis via alleviating angiogenesis in mice
  Condition or outcome area: liver fibrosis; Carthami flos; fibrosis; chronic liver diseases
  Phytomedicine · 2022 · Subject: Hong Hua; 红花; Safflower; Flos Carthami; Carthami Flos · open the herb record · DOI 10.1016/j.phymed.2022.154517
• Publication PMID 36029874 Research model: Animal Experiment
  Maternal safflower oil consumption improve reflex maturation, memory and reduces hippocampal oxidative stress in the offspring rats treated during pregnancy and lactation
  J Affect Disord · 2022 · Subject: Hong Hua; 红花; Safflower; Flos Carthami; Carthami Flos · open the herb record · DOI 10.1016/j.jad.2022.08.058
• Publication PMID 34730571 Research model: Animal Experiment
  Safflower leaf ameliorates cognitive impairment through moderating excessive astrocyte activation in APP/PS1 mice
  Condition or outcome area: AD-related dementia; neurofibrillary tangles; Alzheimer's disease
  Food Funct · 2021 · Subject: Hong Hua; 红花; Safflower; Flos Carthami; Carthami Flos · open the herb record · DOI 10.1039/d1fo01755a
• Publication PMID 34487844 Research model: Clinical Experiment
  Safflower (Carthamus tinctorius L.) oil could improve abdominal obesity, blood pressure, and insulin resistance in patients with metabolic syndrome: A randomized, double-blind, placebo-controlled clinical trial
  Condition or outcome area: abdominal obesity; Metabolic Syndrome; metabolic disorders; MetS
  J Ethnopharmacol · 2021 · Subject: Hong Hua; 红花; Safflower; Flos Carthami; Carthami Flos · open the herb record · DOI 10.1016/j.jep.2021.114590
• Publication PMID 33204394 Research model: Others
  Antioxidant and Antimicrobial Potentials of Seed Oil from Carthamus tinctorius L. in the Management of Skin Injuries
  Condition or outcome area: skin wounds; skin injuries
  Oxid Med Cell Longev · 2020 · Subject: Hong Hua; 红花; Safflower; Flos Carthami; Carthami Flos · open the herb record · DOI 10.1155/2020/4103418