modern wellness · Symptom
Anti-tyrosine phosphatase region of islet antigen-2 antibody positivity
🩺 HPO Source
HPO ID
HPO Label
Anti-tyrosine phosphatase region of islet antigen-2 antibody positivity
HPO Definition
The presence of autoantibodies (immunoglobulins) in the serum that react against the tyrosine phossphatase region of islet antigen 2A (this region is a specific part of IA-2). Usually IA-2A are measured using the intracellular portion of IA-2 (IA-2ic) made up of the protein tyrosine phosphatase (PTP) and juxtamembrane (JM) regions.
🔤 Synonyms (1)
Synonyms
Anti-PTPA antibody positivity
🔼 Broader Terms (1)
HP:0034063Anti-islet antigen-2 antibody positivity