modern wellness · Symptom
Vertebral clefting
🩺 HPO Source
HPO ID
HPO Label
Vertebral clefting
HPO Definition
Schisis (cleft or cleavage) of vertebral bodies.
HPO Curator Comment
Cleft vertebrae result when there are two, instead of one, primary ossification centers in a vertebral body. An unossified cartilaginous brdige may be observed radiographically with the shape of a cleft. If the two ossification centers are ventral/dorsal, a coronal cleft is observed, and if the two ossification centers are left/right, than a sagittal cleft is observed.
🔤 Synonyms (1)
Synonyms
Vertebral clefts
🔗 Cross-References (1)
UMLSC1855828
🔼 Broader Terms (1)
HP:0003312Abnormal form of the vertebral bodies
🏥 Conditions where Vertebral clefting appears
8 · bridged via HPO ↔ OMIM
syndrome OMIM 614701
Cornelia De Lange Syndrome 4
freq: 1/2 ev: PCS
syndrome OMIM 616854
Even-Plus Syndrome
ev: PCS
syndrome OMIM 241500
Hypophosphatasia, Perinatal Lethal
ev: IEA
syndrome OMIM 241500
Infantile Hypophosphatasia
ev: IEA
syndrome OMIM 616803
Lamb-Shaffer Syndrome
freq: HP:0040283 ev: TAS
syndrome OMIM 155050
Maxillonasal Dysplasia, Binder Type
ev: TAS
syndrome OMIM 615709
Sacral Agenesis With Vertebral Anomalies
freq: 1/3 ev: PCS
syndrome OMIM 608681
Spondylocostal Dysostosis, Autosomal Recessive 2
ev: IEA