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THERAPIES & TRADITIONS · COMPARED

Mindfulness-Based Programs, CBT and ACT Compared

Mindfulness-based programs, cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT) compared: how each works, what trials found, and why no single winner exists.

Content last updated . This page has not been medically reviewed.

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Quick answer
Mindfulness-based programs, CBT and ACT are different approaches that sometimes overlap. In head-to-head research, mindfulness-based programs have usually done about as well as CBT, not clearly better or worse. Which one suits you depends on the problem, your preferences and what you can access. This page is information only, not treatment advice.

What each one is

ApproachWhat it doesSource
Mindfulness-based programs (MBSR, MBCT)Teach mindful meditation, with discussion and strategies for stress; MBCT blends mindfulness with parts of CBT[1]
CBTFocuses on how thoughts, beliefs, feelings and behaviour interact and teaches coping skills to deal with things differently[2]
ACTUses acceptance and mindfulness strategies together with commitment and behavior change strategies to increase psychological flexibility[3]

NICE contrasts the two in depression care: group mindfulness work involves increasing awareness and recognition of thoughts and feelings rather than changing them. [2] CBT is a recommended treatment for many mental health problems. [4]

What trials and reviews found

  • Overall: a 2013 meta-analysis found mindfulness-based therapy did not differ from traditional CBT or behavioral therapies, or from pharmacological treatments, though only 9 and 3 comparisons were available. [5] A 2018 analysis of 142 samples (12,005 participants) found mindfulness conditions did not differ from evidence-based treatments. [6]
  • Anxiety: a meta-analysis of 11 trials found no difference between mindfulness-based approaches and CBT on anxiety, depression and sleep quality after treatment. [7] NCCIH, summarizing a 2021 analysis, says only some mindfulness approaches were as effective as CBT, and the few studies that followed people for more than 2 months found no long-term effects. [1]
  • Social anxiety: in 108 unmedicated adults randomized to CBT group therapy, MBSR or waitlist, the two treatments did not differ in reducing negative emotion. [8]
  • Chronic low back pain: in 342 adults, MBSR and CBT both beat usual care and did not differ significantly from each other. [9]
  • Depression relapse: MBCT reduced relapse risk compared with active treatments in an individual-patient analysis. [10] NICE lists group CBT or MBCT as psychological options for people who do not wish to continue antidepressants. [2]

And ACT?

No recent direct ACT-versus-CBT review could be read for this page. An older review judged that there were not enough well-controlled studies to conclude ACT is generally more effective than other active treatments, though the data were promising, and suggested it may work through different processes. [11] Evidence label: promising but limited for a general verdict; Proper evidence not found here for a current head-to-head summary.

Why no winner

  • Most comparisons are small, and reviews of mindfulness note that power may be lacking against active comparators. [12]
  • Adverse effects were inconsistently reported. [12]
  • Participants cannot be blinded to therapy type.
  • Effects differ by condition: relaxation therapy seemed less effective than CBT for post-traumatic stress disorder and obsessive-compulsive disorder in one review. [13]

Fit and practicalities

  • Homework: group MBCT needs willingness to do home practice with recordings; group CBT also uses homework. [2]
  • Hard for some: mindfulness-based groups may be difficult for people with intense or highly distressing thoughts, or who find focusing on the body difficult. [2]
  • Access: in England, many people can self-refer to NHS talking therapies for CBT; some conditions need a GP referral. [4]
  • Qualifications: NICE says group work is delivered preferably by two practitioners, at least one with therapy-specific training. [2] See choosing a qualified practitioner.

Related reading: MBSR, MBCT and structured programs, meditation for pain, attention and depression relapse and mindfulness and meditation for stress.

Frequently asked questions

Is mindfulness as effective as CBT?

In several reviews it did not differ significantly from CBT, but evidence varies by condition. [5][7]

Is ACT a mindfulness therapy?

ACT uses acceptance and mindfulness strategies alongside commitment and behavior change. [3]

Which is better for anxiety?

No clear winner: a meta-analysis found no difference on anxiety, while NCCIH notes only some mindfulness approaches matched CBT. [7][1]

Can mindfulness replace antidepressants?

Not as a general rule. NICE lists MBCT as an option for some people at higher risk of relapse, with clinician guidance. [2]

Can I combine them?

Often yes, and MBCT already blends mindfulness with CBT elements. [1] Ask a clinician about sequencing.

More details: evidence, limits and cautions

The details behind this page: cautions, limits of the evidence and where sources disagree. Open any note to read it.

When to seek care
If low mood, anxiety or thoughts of self-harm are affecting daily life, see a clinician. In the US, call or text 988 for the 988 Suicide & Crisis Lifeline. [14] Do not stop medicine or therapy to try mindfulness.
References
  1. National Center for Complementary and Integrative Health. Meditation and Mindfulness: Effectiveness and Safety. Read 2026-10-22.
  2. National Institute for Health and Care Excellence. Depression in adults: treatment and management (NG222), Recommendations. Published 29 June 2022. Read 2026-10-22.
  3. Association for Contextual Behavioral Science. Acceptance and Commitment Therapy (ACT). Read 2026-10-22.
  4. NHS. Cognitive behavioural therapy (CBT). Read 2026-10-22.
  5. Khoury B, et al. Mindfulness-based therapy: a comprehensive meta-analysis. Clin Psychol Rev. 2013. Read 2026-10-22.
  6. Goldberg SB, et al. Mindfulness-based interventions for psychiatric disorders: A systematic review and meta-analysis. Clin Psychol Rev. 2018. Read 2026-10-22.
  7. Mindfulness-based therapy versus cognitive behavioral therapy for people with anxiety symptoms: a systematic review and meta-analysis of random controlled trials. Ann Palliat Med. 2021. Read 2026-10-22.
  8. Evaluation of Cognitive Behavioral Therapy vs Mindfulness Meditation in Brain Changes During Reappraisal and Acceptance Among Patients With Social Anxiety Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2021. Read 2026-10-22.
  9. Cherkin DC, et al. Effect of Mindfulness-Based Stress Reduction vs Cognitive Behavioral Therapy or Usual Care on Back Pain and Functional Limitations in Adults With Chronic Low Back Pain: A Randomized Clinical Trial. JAMA. 2016. Read 2026-10-22.
  10. Kuyken W, et al. Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse: An Individual Patient Data Meta-analysis From Randomized Trials. JAMA Psychiatry. 2016. Read 2026-10-22.
  11. Hayes SC, et al. Acceptance and commitment therapy: model, processes and outcomes. Behav Res Ther. 2006. Read 2026-10-22.
  12. Goldberg SB, et al. The Empirical Status of Mindfulness-Based Interventions: A Systematic Review of 44 Meta-Analyses of Randomized Controlled Trials. Perspect Psychol Sci. 2022. Read 2026-10-22.
  13. National Center for Complementary and Integrative Health. Relaxation Techniques: What You Need To Know. Read 2026-10-22.
  14. 988 Suicide & Crisis Lifeline. 988lifeline.org. Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.