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Perilla Seeds: Nutrients, What Research Shows and Safety

Perilla seeds (deulkkae, egoma) as a food: omega-3 ALA, fiber and minerals, seed allergy reports from Korea, how the seed differs from shiso leaf, and what research shows.

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Close-up of perilla seeds: nutrients, what research shows and safety

Perilla seeds are the small round seeds of Perilla frutescens, a plant in the mint family (Lamiaceae). In Korea the seeds are called deulkkae and in Japan egoma. They are toasted and ground as a seasoning, or pressed into a nutty oil that is very rich in the plant omega-3 fat ALA. Do not confuse the seed with the leaf: the leaves are eaten as a vegetable or garnish (kkaennip in Korea, shiso in Japan), and this page is only about the seed and, briefly, its oil. [1][8] It keeps the food apart from supplements and from hype. There is no USDA entry for perilla seeds, so the numbers come from a Korean food composition table and research papers.

Read this first

  • Seed allergy is real. In a 2022 school survey of about 12,500 Korean children, perilla seed allergy affected about 0.11% and perilla-seed anaphylaxis about 0.02%,, an allergen the authors describe as uniquely seen in that survey. [4] Case reports describe severe reactions in young children. [7][5] For trouble breathing or swelling of the face or throat, call 911 (or your local emergency number).
  • Roasting perilla seeds has caused occupational asthma in a worker exposed to the smoke. [6]
  • Perilla seed oil is one of the richest plant sources of ALA, about 54 to 64% of its fatty acids. [1] The oil, not the seed, is what most health studies tested.
  • Honest summary: the seed is a food rich in fat, fiber and several minerals. Reported health benefits rest mostly on lab and animal studies plus a few small human trials of the oil. [1]

What is in it (research values, not USDA)

USDA FoodData Central has no entry for perilla seeds. The values below are for dry perilla seed from the Korean Food Composition Table (Rural Development Administration, 2011), as reproduced in a 2023 Frontiers in Nutrition article. [2] The article's table also lists roasted seed. We did not open the Korean table itself, and the article's layout made the dry and roasted columns hard to tell apart, so check these numbers before relying on them. Per-serving values are our calculation for 1 ounce (28 g, the USDA/MyPlate unit), using a factor of 0.2835.

NutrientPer 100 g (dry seed)Per 1 ounce (28 g), our calculation% Daily Value per ounce
Energy530 kcal150 kcalnot set
Total fat39.7 g11.3 g14%
Protein22.7 g6.4 g13%
Fiber22 g6.2 g22%
Carbohydrate (total)29.3 g8.3 gnot calculated
Manganese3.69 mg1.05 mg45%
Copper1.21 mg0.34 mg38%
Magnesium254 mg72 mg17%
Phosphorus716 mg203 mg16%
Iron7.74 mg2.2 mg12%
Zinc4.8 mg1.4 mg12%
Calcium391 mg111 mg9%
Potassium583 mg165 mg4%
Alpha-linolenic acid (ALA, omega-3)about 53 to 62% of the seed oil [2]roughly 6 to 7 g by our rough estimateno DV

% Daily Value uses the FDA 2016 Daily Values; values vary with variety, growing place, roasting and storage. The ALA row is our estimate: it multiplies the fat figure by the percentage of ALA reported for the oil, and it assumes all the fat is seed oil. We did not read a direct measurement of ALA per 100 g of whole seed. The NIH Adequate Intake for ALA is 1.6 g a day for men and 1.1 g for women (US Institute of Medicine, 2002, as given by the Linus Pauling Institute). [3] FDA sets no Daily Value for ALA.

On fats: the oil is reported as 35 to 45% of the seed, and about 54 to 64% of the oil is ALA, with linoleic acid (omega-6) about 13 to 14%. [1] The article from Frontiers gives ALA at 53 to 62% and linoleic acid 10 to 13%. [2] The same table lists protein at about 23 g per 100 g, and a review gives 20 to 30%. [1][2] Tocopherols are reported at roughly 662 to 731 mg per kg of oil as gamma-tocopherol and only 5 to 20 mg per kg as alpha-tocopherol. [1] The seed table lists rosmarinic acid at 368 mg and luteolin at about 10 mg per 100 g of dry seed. [2] These plant compounds come from lab analysis. We did not read a human trial showing they act in the body when the seed is eaten.

What research says

Health goalWhat the sources foundStrength of evidenceWhat was studied
Fat, fiber and mineralsA Korean table lists 39.7 g fat, 22 g fiber, and large amounts of manganese, copper, magnesium and phosphorus per 100 g. [2]Established (nutrient content)Food composition
Omega-3 (ALA) sourceThe oil is reported as 54 to 64% ALA. [1] The body converts only some ALA to EPA and DHA: about 8% to EPA in men and 21% in women, with 0 to 4% (men) and 9% (women) going on to DHA in healthy young adults. [3]Established (ALA content); insufficient evidence (benefit from converting it)Composition analyses; short conversion studies
Blood fats and inflammation (CRP)A review lists a trial in 36 adults with high blood fats who took perilla oil capsules for 56 days, with lower lipids and CRP. [1]Promising but limitedOil capsules; small; we did not read the trial itself
Antioxidant status, thinking and bone markers in older adultsA review lists a 12-month Japanese study giving 7 mL a day of the oil to older adults, with benefits in these markers. [1]Insufficient evidenceOil; small; summarized secondhand
Gut bacteria, quality of life in cancer careA 2023 article cites an 8-week oil trial in female athletes and a report of oil added to cancer drugs, but gives no numbers. [2]Insufficient evidenceOil; details not available to us
Heart disease, cancer, brain diseaseThe 2024 review says benefits rest mainly on cell and animal work and calls for large, long trials. [1]Lab or animal onlySeed oil and protein extracts in cells and animals

Eaten as food vs taken as oil, extract or supplement. The human studies in the table used perilla oil, often in capsules or as a measured spoonful, not seeds sprinkled on food. [1] A small trial of oil does not tell us what toasted seeds in a meal do. We did not find a trial of the seeds themselves. Observational studies, if any, show association, not proof; we did not read one on perilla seeds.

How much is a normal serving

We did not find an official portion for perilla seeds. We use 1 ounce (28 g), the USDA/MyPlate unit for nuts and seeds, so the numbers can be compared with other pages on this site. This is information, not a prescription. In Korean cooking the toasted ground seed is a seasoning added to soups, vegetables, noodles and kimchi, and the oil is a nutty cooking oil and condiment, so everyday amounts are usually small. [8] One ounce is about 150 kcal by our calculation from the Korean table, so the seed is energy dense. [2] We found no meta-analysis on perilla seeds and body weight, so we make no weight claim.

For comparison, the toasted seed is a condiment in the same way as sesame seeds. The Korean table lists both dry and roasted seed with similar protein and fat, and some minerals read higher in the roasted column. We did not find a source explaining why, so we make no claim about roasting. [2]

Safety, allergy and medicines

  • Seed allergy. A 2022 Korean school survey (about 12,500 children) found perilla seed allergy in about 0.11% and anaphylaxis from it in about 0.02%, and the authors describe perilla seed as an allergen seen uniquely in that setting. [4] A 2026 study says perilla seed is a leading cause of seed-induced anaphylaxis in Korean children, and found the main allergens in the seed's oil bodies, a protein called oleosin. [5] A 2006 report describes two cases of anaphylaxis caused by perilla seed (we read the citation record only). [7] A 2025 review covers tree nut and seed allergies in general. [9] We did not find how common perilla allergy is outside Korea and Japan. If you have a seed or nut allergy, ask your allergist before trying perilla. See nut and seed allergy basics and food allergy basics and emergency signs. For trouble breathing or swelling of the face or throat, call 911.
  • Cross-reactivity with sesame or other seeds. Proper evidence not found in the sources we read.
  • Roasting smoke. A Korean case report describes occupational asthma in a man who roasted grains for 10 years and became short of breath only when roasting perilla seeds. A test with smoke from roasting perilla produced an asthma response. [6] This is one case.
  • Handling the plant. An encyclopedia entry says handling perilla leaves or oil may cause contact dermatitis and that eating large amounts of the seeds has caused anaphylaxis. [8] We treat this as a pointer, not as strong evidence.
  • Seed versus leaf. Perilla leaf (shiso, kkaennip) is a different part of the plant, used as a vegetable. This page does not cover leaf extracts or capsules. The plant's aroma compound perilla ketone is toxic to cattle and horses that graze it; this is a livestock problem and not a finding about seeds eaten by people. [8]
  • Medicines. Proper evidence not found in the sources we read for perilla seeds. For comparison only: the Linus Pauling Institute says high doses of flaxseed oil may inhibit platelet aggregation, so people on blood thinners should use caution; we did not read a source that tested this for perilla. [3] See foods and medicine interactions.
  • Kidney disease. One ounce has about 165 mg potassium and 203 mg phosphorus by our calculation. [2] We did not read a kidney-diet source naming perilla seeds, so ask your kidney team. See foods, kidney disease, potassium and oxalates.
  • Pregnancy and children. Proper evidence not found in the sources we read. Perilla seed allergy has been studied mainly in Korean children. [4][5] See foods for babies and toddlers.

Choosing, storing and food safety

  • The oil is high in ALA, which oxidizes easily. A related review of plant omega-3 oils on this site discusses spoilage; see chia, hemp, perilla and walnut oils.
  • We did not read a perilla-specific source on storage, mold or aflatoxin. General advice is on storing nuts and seeds: rancidity, mold and aflatoxin.
  • Check the label. "Perilla" can mean the seed, the oil, leaf products or mixed seasonings, and names for the varieties differ between countries. [8]

Related pages

Nut or seedPerilla frutescens

Health connections for Perilla Seeds

What research links to eating or drinking this food, and how strong the evidence is. Many studies are observational or use juice, powder, oil or extracts rather than the food as eaten; each card says which.

Plant omega-3 fat (ALA) in the seed and oil

Established role

Perilla seed oil is reported as about 54 to 64% ALA (other analyses 53 to 62%). The seed is about 35 to 45% oil, so one ounce holds roughly 6 to 7 g of ALA by our rough estimate.

Supplements: Oil is a different product from the seed; nutrient content does not prove a health effect.

Fiber, protein and minerals

Established role

A Korean table lists dry seed at 22 g fiber, 22.7 g protein, 3.69 mg manganese, 1.21 mg copper and 254 mg magnesium per 100 g. One ounce gives 45% of the manganese and 38% of the copper Daily Value (our calculation).

Supplements: This table is not USDA data and the dry and roasted columns were hard to tell apart.

Perilla oil and blood fats

Preliminary or mixed

A review lists a trial in 36 adults with high blood fats who took perilla oil capsules for 56 days, with lower lipids and CRP. We did not read the trial.

Supplements: Oil capsules were tested, not seeds; small and secondhand.

Perilla oil in older adults

Not enough evidence

A review lists a 12-month Japanese study of 7 mL a day of the oil with benefits for antioxidant, thinking-related and bone markers.

Supplements: Small, summarized secondhand; no seed trial.

Plant compounds: rosmarinic acid and luteolin

Lab or animal research only

The Korean table lists rosmarinic acid (368 mg) and luteolin (about 10 mg) per 100 g of dry seed, and gamma-tocopherol is the main vitamin E form in the oil.

Supplements: No human trial of these compounds from the seed was read.

Heart, cancer and brain claims

Lab or animal research only

A 2024 review says the benefits rest mainly on cell and animal work and calls for large, long clinical trials.

Supplements: Not shown in people.

Limited conversion of ALA to EPA and DHA

Not enough evidence

In healthy young adults about 8% of dietary ALA was converted to EPA in men and about 21% in women, with 0 to 4% (men) and about 9% (women) going on to DHA.

Supplements: No trial of perilla changing EPA or DHA levels was read.

Connected topics

Open a group to see how each topic connects and how strong the evidence is.

Body systems (2)
  • Immune SystemDocumented risk

    Perilla seed allergy, including anaphylaxis, is documented in Korean children.

  • Respiratory SystemDocumented risk

    One case of occupational asthma from roasting perilla seeds.

Body parts (2)
  • Immune SystemDocumented risk

    Perilla seed allergy, including anaphylaxis, is documented in Korean children.

  • LungsDocumented risk

    One case of occupational asthma from roasting perilla seeds.

Root causes (1)
  • Poor DietEstablished role

    The seed is a source of fiber, fat including plant omega-3, and minerals in an overall diet.

Habits (1)
  • Balanced NutritionEstablished role

    Toasted seed or oil can be one plant source of ALA in a varied diet.

Conditions & symptoms (3)
  • Food AllergyDocumented risk

    Perilla seed allergy is documented in Korean children (about 0.11% in a school survey).

  • Food AnaphylaxisDocumented risk

    Perilla seed has caused anaphylaxis in children (about 0.02% in a Korean school survey; case reports).

  • AsthmaDocumented risk

    One case of occupational asthma from roasting perilla seeds.

Documented risks and interactions (2)
  • Perilla seed allergy. A 2022 Korean school survey found perilla seed allergy in about 0.11% of children and anaphylaxis in about 0.02%; the main allergens are oleosin proteins in the seed's oil bodies; a 2006 report describes two anaphylaxis cases.
  • Asthma from roasting smoke. One Korean case report describes occupational asthma in a man who roasted perilla seeds; a test with the roasting smoke produced an asthma response.

Explore all 37 nuts and seeds

Frequently asked questions

Are perilla seeds the same as shiso?

They come from the same species, but they are different plant parts and often different varieties. Shiso is the leaf, used as a garnish or vegetable; deulkkae and egoma are the seeds and the oil type. [8][1] Names vary by country, so read the label.

Do perilla seeds have omega-3?

Yes. The oil is reported as about 54 to 64% ALA, a plant omega-3. [1] The body converts only part of ALA to EPA and DHA. [3]

Can you be allergic to perilla seeds?

Yes. A Korean school survey found perilla seed allergy in about 0.11% of children, and case reports describe anaphylaxis. [4][7] For trouble breathing or swelling of the face or throat, call 911.

Does perilla oil lower cholesterol?

A review lists one small trial of 36 adults with high blood fats, using oil capsules for 56 days, with lower lipids and CRP. [1] We did not read the trial and no trial of the seeds is known to us, so the evidence is limited.

How are perilla seeds used in cooking?

In Korea the seeds are toasted and ground as a seasoning for soups, vegetables, noodles and kimchi, or pressed into a nutty oil. [8]

References
  1. Guan L et al. Perilla Seed Oil and Protein: Composition, Health Benefits, and Potential Applications in Functional Foods. Molecules 2024;29(22):5258. Read 2026-10-23 (first part of the text).
  2. Aochen C et al. Perilla frutescens L.: a dynamic food crop worthy of future challenges. Front Nutr 2023;10:1130927. Table 1 cites the Korean Food Composition Table (Rural Development Administration, South Korea, 2011), which we did not open. Read 2026-10-23.
  3. Linus Pauling Institute, Oregon State University. Essential Fatty Acids. Read 2026-10-23 (ALA Adequate Intake of the US Institute of Medicine, 2002; conversion rates; safety).
  4. Jeon YH et al. Prevalence of Immediate-Type Food Allergy and Food-Induced Anaphylaxis in Korean Schoolchildren. Allergy Asthma Immunol Res 2026. PMID 42223040. Abstract read 2026-10-23 via Europe PMC.
  5. Jeong K et al. Advancing allergen characterization in Perilla seed: an oil body purification approach. Allergy Asthma Clin Immunol 2026. PMID 41618458. Abstract read 2026-10-23 via Europe PMC.
  6. Jung S et al. Occupational asthma caused by inhaling smoke from roasting perilla seeds. Allergy Asthma Respir Dis 2013;1(1):90-93. Abstract read 2026-10-23.
  7. Jeong YY, Park H-S, Choi JH, Kim S-H, Min K-U. Two cases of anaphylaxis caused by perilla seed. J Allergy Clin Immunol 2006;117(6):1505-1506. Citation record read 2026-10-23 (no abstract available to us).
  8. Wikipedia. Perilla frutescens. An encyclopedia, used only for naming, culinary uses and general notes. Read 2026-10-23.
  9. Jeong K, Lee S. Update on Tree Nut and Seed Allergies: Prevalence, Clinical Characteristics, Diagnosis, and Management. Allergy Asthma Immunol Res 2025. PMID 41330701. Abstract read 2026-10-23 via Europe PMC.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.