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Ingredient
45,885
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Gene Target
15,695
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Disease
30,467
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Evidence
23,241
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
Beta-carotene
16
Clinical Trials
12
Meta-Analyses
0
PubMed References
Top Conditions Studied with Beta-carotene
Vitamin A Deficiency 2
Healthy 2
Vitamin A Deficiency|Maternal Mortality|Infant Mortality 1
Bioavailability 1
Recent evidence suggests that oxidative stress plays an impo 1
Beta-carotene Bioavailability|Vitamin A Deficiency 1
Nutrients (carotenoids) absorption 1
Retinopathy of Prematurity 1
Mortality from any cause in healthy subjects or subjects dia 1
Oxidative DNA Damage 1
Malaria is caused in humans by five species of single-celled 1
Neoplasms 1
📋 Sample Trials
NCT00128752
The CARO Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in Healthy Subjects
Completed
NCT00128804
The STOVITA Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in Ileostomy Patients
Completed
NCT00169845
Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancies in Head and Neck Cancer Patients
Completed · Phase 3
📊 Sample Meta-Analyses
CRD42019122137
Dose-response analysis of dietary vitamin A and beta-carotene intake with the risk of lung cancer
Lung cancer is a leading cause of cancer mortality worldwide, with a complex car
CRD42020188539
Effects of dietary fats on the bioaccessibility and bioavailability of the carotenoids. A Systematic Review and Meta-analysis of clinical trial and in-vitro research
Nutrients (carotenoids) absorption
CRD42021259354
Association between beta carotene supplementation and mortality: a systematic review and meta-analysis of randomized controlled trials
Mortality from any cause in healthy subjects or subjects diagnosed with a specif
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for Beta-carotene
⚗️ Identity
Name
Beta-carotene
Aliases / Synonyms
7235-40-7; beta Carotene; beta,beta-Carotene; Solatene; Betacarotene; Provatene; Carotaben; Provitamin A; Serlabo
🧪 Chemistry
Molecular Weight
536.8880
LogP
12.6058
Drug-likeness
0.244
Rotatable Bonds
10
🔬 Structures
Canonical SMILES
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C)C)C
Isomeric SMILES
CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(CCCC2(C)C)C)\C)\C)/C)/C
InChIKey
OENHQHLEOONYIE-JLTXGRSLSA-N
InChI
InChI=1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
🔗 External References
HERB DB
PubChem CID
NPASS
NPC17810
HIT
C1177
TCMID
23745; 23963; 15349
TCM-ID
5884; 21852
🔍 Raw view — every non-empty column on this row (30 fields)
name
Beta-carotene
common names
7235-40-7; beta Carotene; beta,beta-Carotene; Solatene; Betacarotene; Provatene; Carotaben; Provitamin A; Serlabo
herb ingredient id
HBIN019762
canonical smiles
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C)C)C
isomeric smiles
CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(CCCC2(C)C)C)\C)\C)/C)/C
inchi
InChI=1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
inchikey
OENHQHLEOONYIE-JLTXGRSLSA-N
mol wt
536.8880
num h acceptors
0
num h donors
0
mol logp
12.6058
num rotatable bonds
10
drug likeness
0.244
tcmid ingredient id
23745; 23963; 15349
tcm id ingredient id
5884; 21852
pubchem cid
5280489
npass id
NPC17810
hit id
C1177
📋 Clinical Trials
12 · subject of clinical studyNCT00128752 The CARO Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in Heal
→ Healthy
NCT00128804 The STOVITA Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in I
→ Healthy|Ileostomy
NCT00169845 Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancie
→ Neoplasms
NCT00198822 Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and In
→ Vitamin A Deficiency|Maternal Mortality|Infant Mor
NCT00712647 Carotene and Retinol Efficacy Trial
→ Lung Cancer
NCT02550483 Novel Metabolites of Beta-Carotene and Lycopene
→ Healthy
NCT03492593 Lycopene and Beta-carotene Metabolism in the Digestive Tract of Healthy Men
→ Digestion Chambers|Stability and Metabolism of Car
NCT04697355 Effect of Naringenin and Beta Carotene on Energy Expenditure
→ Energy Expenditure|Safety Issues|Glucose Metabolis
NCT00356252 Biological Functions of Carotenoids in Humans
→ Oxidative DNA Damage
NCT00636038 Bioavailability of Yellow Maize Carotenoids in Humans
→ Vitamin A Status
NCT00680212 Vitamin A Equivalence of Plant Carotenoids in Children
→ Vitamin A Deficiency
NCT00872664 Skin and Serum Carotenoids in Preterm Infants Fed on a Formula Supplemented With
→ Retinopathy of Prematurity
📊 Meta-Analyses
12 · systematic reviewCRD42019122137 Dose-response analysis of dietary vitamin A and beta-carotene intake with the ri
→ Lung cancer is a leading cause of cancer mortality
CRD42020188539 Effects of dietary fats on the bioaccessibility and bioavailability of the carot
→ Nutrients (carotenoids) absorption
CRD42021259354 Association between beta carotene supplementation and mortality: a systematic re
→ Mortality from any cause in healthy subjects or su
CRD42021285084 Effect of carotenoids supplementation on type 2 diabetes and glycemic profile
→ Diabetes mellitus (DM) is a chronic metabolic diso
CRD42021287694 The association of plasma carotenoids and vitamins with risk of age-related macu
→ Age-related macular degeneration
CRD42022318388 Vitamin C, Vitamin E, β-carotene and risk of Parkinson’s disease: a systematic r
→ Recent evidence suggests that oxidative stress pla
CRD42022340579 Carrot and carotene and multiple health outcomes: An umbrella review of the evid
→ Carrot is consumed widely and deeply loved by peop
CRD42022343482 Intakes or circulating levels of vitamin C, vitamin E, and beta-carotene and the
→ Type 2 diabetes (T2D), insulin secretion/deficienc
CRD42022344012 Association of carotenoids with risk of gastric cancer: A meta-analysis.
→ Gastric cancer.
CRD42023418843 The effects of nutrition interventions on adverse perinatal outcomes: an umbrell
→ To evaluate the quality of evidence and effectiven
CRD42023422784 Assess the effectiveness of beta-carotene on cognitive function through a system
→ The review takes into consideration health subject
CRD42023453837 Effect of malaria on beta-carotene levels
→ Malaria is caused in humans by five species of sin
How to read these connections
Each box lists records connected to the one you are viewing, and says how the connection was made. A connection shows that two records are related in the source data. It does not show that something works, is safe or should be used, and a record with many connections is not necessarily better studied or more effective.
- Study records (trials, systematic reviews, publications): the study names this subject. Registered or ongoing studies have no results here, and animal or cell research does not show an effect in people.
- Source-database links (for example herb and compound, compound and gene target): taken from the imported databases and not independently checked by us.
- Name matches (for example formula and herb, or a condition named in a study): found by matching names, so they can be wrong. Treat them as leads, not findings.