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Plus 6,743 TCM formulas connecting herbs together
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⚗️ Ingredient

Beta-carotene

Open on HERB 2.0 ↗
16
Clinical Trials
12
Meta-Analyses
0
PubMed References
Top Conditions Studied with Beta-carotene
Vitamin A Deficiency 2 Healthy 2 Vitamin A Deficiency|Maternal Mortality|Infant Mortality 1 Bioavailability 1 Recent evidence suggests that oxidative stress plays an impo 1 Beta-carotene Bioavailability|Vitamin A Deficiency 1 Nutrients (carotenoids) absorption 1 Retinopathy of Prematurity 1 Mortality from any cause in healthy subjects or subjects dia 1 Oxidative DNA Damage 1 Malaria is caused in humans by five species of single-celled 1 Neoplasms 1
📋 Sample Trials
NCT00128752
The CARO Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in Healthy Subjects
Completed
NCT00128804
The STOVITA Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in Ileostomy Patients
Completed
NCT00169845
Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancies in Head and Neck Cancer Patients
Completed · Phase 3
📊 Sample Meta-Analyses
CRD42019122137
Dose-response analysis of dietary vitamin A and beta-carotene intake with the risk of lung cancer
Lung cancer is a leading cause of cancer mortality worldwide, with a complex car
CRD42020188539
Effects of dietary fats on the bioaccessibility and bioavailability of the carotenoids. A Systematic Review and Meta-analysis of clinical trial and in-vitro research
Nutrients (carotenoids) absorption
CRD42021259354
Association between beta carotene supplementation and mortality: a systematic review and meta-analysis of randomized controlled trials
Mortality from any cause in healthy subjects or subjects diagnosed with a specif
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for Beta-carotene
⚗️ Identity
Name
Beta-carotene
Aliases / Synonyms
7235-40-7; beta Carotene; beta,beta-Carotene; Solatene; Betacarotene; Provatene; Carotaben; Provitamin A; Serlabo
🧪 Chemistry
Molecular Weight
536.8880
LogP
12.6058
Drug-likeness
0.244
Rotatable Bonds
10
🔬 Structures
Canonical SMILES
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C)C)C
Isomeric SMILES
CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(CCCC2(C)C)C)\C)\C)/C)/C
InChIKey
OENHQHLEOONYIE-JLTXGRSLSA-N
InChI
InChI=1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
🔗 External References
HERB DB
HBIN019762 ↗
PubChem CID
5280489 ↗
NPASS
NPC17810
HIT
C1177
TCMID
23745; 23963; 15349
TCM-ID
5884; 21852
🔍 Raw view — every non-empty column on this row (30 fields)
name
Beta-carotene
common names
7235-40-7; beta Carotene; beta,beta-Carotene; Solatene; Betacarotene; Provatene; Carotaben; Provitamin A; Serlabo
herb ingredient id
HBIN019762
canonical smiles
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C)C)C
isomeric smiles
CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(CCCC2(C)C)C)\C)\C)/C)/C
inchi
InChI=1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
inchikey
OENHQHLEOONYIE-JLTXGRSLSA-N
mol wt
536.8880
num h acceptors
0
num h donors
0
mol logp
12.6058
num rotatable bonds
10
drug likeness
0.244
tcmid ingredient id
23745; 23963; 15349
tcm id ingredient id
5884; 21852
pubchem cid
5280489
npass id
NPC17810
hit id
C1177

🏥 Linked Health Topics

3 · studied for these conditions (text bridge)
Neoplasms
group
Retinopathy of Prematurity
syndrome
Vitamin A Deficiency
syndrome

📋 Clinical Trials

12 · subject of clinical study
NCT00128752 The CARO Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in Heal
→ Healthy
NCT00128804 The STOVITA Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in I
→ Healthy|Ileostomy
NCT00169845 Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancie
→ Neoplasms
NCT00198822 Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and In
→ Vitamin A Deficiency|Maternal Mortality|Infant Mor
NCT00712647 Carotene and Retinol Efficacy Trial
→ Lung Cancer
NCT02550483 Novel Metabolites of Beta-Carotene and Lycopene
→ Healthy
NCT03492593 Lycopene and Beta-carotene Metabolism in the Digestive Tract of Healthy Men
→ Digestion Chambers|Stability and Metabolism of Car
NCT04697355 Effect of Naringenin and Beta Carotene on Energy Expenditure
→ Energy Expenditure|Safety Issues|Glucose Metabolis
NCT00356252 Biological Functions of Carotenoids in Humans
→ Oxidative DNA Damage
NCT00636038 Bioavailability of Yellow Maize Carotenoids in Humans
→ Vitamin A Status
NCT00680212 Vitamin A Equivalence of Plant Carotenoids in Children
→ Vitamin A Deficiency
NCT00872664 Skin and Serum Carotenoids in Preterm Infants Fed on a Formula Supplemented With
→ Retinopathy of Prematurity

📊 Meta-Analyses

12 · systematic review
CRD42019122137 Dose-response analysis of dietary vitamin A and beta-carotene intake with the ri
→ Lung cancer is a leading cause of cancer mortality
CRD42020188539 Effects of dietary fats on the bioaccessibility and bioavailability of the carot
→ Nutrients (carotenoids) absorption
CRD42021259354 Association between beta carotene supplementation and mortality: a systematic re
→ Mortality from any cause in healthy subjects or su
CRD42021285084 Effect of carotenoids supplementation on type 2 diabetes and glycemic profile
→ Diabetes mellitus (DM) is a chronic metabolic diso
CRD42021287694 The association of plasma carotenoids and vitamins with risk of age-related macu
→ Age-related macular degeneration
CRD42022318388 Vitamin C, Vitamin E, β-carotene and risk of Parkinson’s disease: a systematic r
→ Recent evidence suggests that oxidative stress pla
CRD42022340579 Carrot and carotene and multiple health outcomes: An umbrella review of the evid
→ Carrot is consumed widely and deeply loved by peop
CRD42022343482 Intakes or circulating levels of vitamin C, vitamin E, and beta-carotene and the
→ Type 2 diabetes (T2D), insulin secretion/deficienc
CRD42022344012 Association of carotenoids with risk of gastric cancer: A meta-analysis.
→ Gastric cancer.
CRD42023418843 The effects of nutrition interventions on adverse perinatal outcomes: an umbrell
→ To evaluate the quality of evidence and effectiven
CRD42023422784 Assess the effectiveness of beta-carotene on cognitive function through a system
→ The review takes into consideration health subject
CRD42023453837 Effect of malaria on beta-carotene levels
→ Malaria is caused in humans by five species of sin
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables