Relationship Graph Explorer

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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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🧪

Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Cortisone

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Cortisone

Osteo Arthritis Shoulders 1 Hip Injuries 1 Thyroidectomy|Post-operative Swallowing Disorders 1 QTc-interval 1 Osteoarthritis, Knee 1

📋 Sample Trials

NCT02639039

Cortisone Injection vs Trigger Point Dry Needling Fin the Treatment of Greater Trochanter Pain Syndrome: A Pilot Study

Completed · Phase 4

NCT03082339

Cortisone and QTc-Interval

Completed

NCT03580148

BMA vs Cortisone for Glenohumeral Osteoarthritis

Completed · Phase 2|Phase 3

📊 Sample Meta-Analyses

None linked yet.

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for Cortisone

⚗️ Identity

Name

Cortisone

Aliases / Synonyms

53-06-5; Kendall's compound E; Cortisate; Cortistal; Cortivite; Andreson; Cortisal; Reichstein's substance FA; Adrenalex

🧪 Chemistry

Molecular Weight

360.4500

LogP

1.9898

Drug-likeness

0.786

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

CC12CCC(=O)C=C1CCC3C2C(=O)CC4(C3CCC4(C(=O)CO)O)C

Isomeric SMILES

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C

InChIKey

MFYSYFVPBJMHGN-ZPOLXVRWSA-N

InChI

InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

🔗 External References

HERB DB

HBIN021533 ↗

PubChem CID

222786 ↗

NPASS

NPC233118

TCMID

4097

TCM-ID

5480

🔍 Raw view — every non-empty column on this row (29 fields)

name

Cortisone

common names

53-06-5; Kendall's compound E; Cortisate; Cortistal; Cortivite; Andreson; Cortisal; Reichstein's substance FA; Adrenalex

herb ingredient id

HBIN021533

canonical smiles

CC12CCC(=O)C=C1CCC3C2C(=O)CC4(C3CCC4(C(=O)CO)O)C

isomeric smiles

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C

inchi

InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

inchikey

MFYSYFVPBJMHGN-ZPOLXVRWSA-N

mol wt

360.4500

num h acceptors

num h donors

mol logp

1.9898

num rotatable bonds

drug likeness

0.786

tcmid ingredient id

4097

tcm id ingredient id

5480

pubchem cid

222786

npass id

NPC233118

🏥 Linked Health Topics

1 · diseases via target pathways

Osteoarthritis, Knee

syndrome

📋 Clinical Trials

5 · subject of clinical study

NCT02639039 Cortisone Injection vs Trigger Point Dry Needling Fin the Treatment of Greater T

→ Hip Injuries

NCT03082339 Cortisone and QTc-Interval

→ QTc-interval

NCT03580148 BMA vs Cortisone for Glenohumeral Osteoarthritis

→ Osteo Arthritis Shoulders

NCT00279903 Is Botox Effective in Relieving Pain From Knee Osteoarthritis?

→ Osteoarthritis, Knee

NCT02855866 Interest of Cryotherapy or Cortisone Aerosol Therapy in Early Post-operative Swa

→ Thyroidectomy|Post-operative Swallowing Disorders

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables