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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.
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Ingredient
44,598
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Gene Target
15,695
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Disease
30,467
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
Coumarin
1
Clinical Trials
1
Meta-Analyses
2
PubMed References
Top Conditions Studied with Coumarin
📋 Sample Trials
NCT01848210
Efficacy and Safety of Coumarin and Troxerutin in the Symptomatic Treatment of Chronic Venous Insufficiency
Completed · Phase 4
📊 Sample Meta-Analyses
CRD42020223555
Associated factors of medication adherence employing coumarin derivatives or direct oral anticoagulants: a systematic review
Thrombosis is a mechanism for the development of diseases responsible for high r
📚 Sample References
PMID 32991865
Synergistic transport of a fluorescent coumarin probe marks coumarins as pharmacological modulators of Organic anion-transporting polypeptide, OATP3A1
Biochem Pharmacol · 2020
PMID 35177961
Comparison Between Hesperidin, Coumarin, and Deferoxamine Iron Chelation and Antioxidant Activity Against Excessive Iron in the Iron Overloaded Mice
Front Neurosci · 2022
⚗️ All Ingredient data fields for Coumarin
⚗️ Identity
Name
Coumarin
Aliases / Synonyms
91-64-5; 2H-Chromen-2-one; 2H-1-Benzopyran-2-one; cumarin; 1,2-Benzopyrone; chromen-2-one; Rattex; Coumarinic anhydride; Tonka bean camphor
🧪 Chemistry
Molecular Weight
146.1450
LogP
1.7930
Drug-likeness
0.53
Oral Bioavailability
29.1680
H-Bond Acceptors
2
🔬 Structures
Canonical SMILES
C1=CC=C2C(=C1)C=CC(=O)O2
Isomeric SMILES
C1=CC=C2C(=C1)C=CC(=O)O2
InChIKey
ZYGHJZDHTFUPRJ-UHFFFAOYSA-N
InChI
InChI=1S/C9H6O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H
🔗 External References
HERB DB
PubChem CID
CAS Number
NPASS
NPC139891
HIT
C1259
SymMap
43
TCMID
4140; 32978
TCMSP
MOL000431
TCM-ID
5453
🔍 Raw view — every non-empty column on this row (34 fields)
name
Coumarin
common names
91-64-5; 2H-Chromen-2-one; 2H-1-Benzopyran-2-one; cumarin; 1,2-Benzopyrone; chromen-2-one; Rattex; Coumarinic anhydride; Tonka bean camphor
herb ingredient id
HBIN021608
canonical smiles
C1=CC=C2C(=C1)C=CC(=O)O2
isomeric smiles
C1=CC=C2C(=C1)C=CC(=O)O2
inchi
InChI=1S/C9H6O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H
inchikey
ZYGHJZDHTFUPRJ-UHFFFAOYSA-N
mol wt
146.1450
num h acceptors
2
num h donors
0
mol logp
1.7930
num rotatable bonds
0
drug likeness
0.53
ob score
29.1680
cas id
91-64-5
symmap mol id
43
tcmid ingredient id
4140; 32978
tcmsp ingredient id
MOL000431
tcm id ingredient id
5453
pubchem cid
323
npass id
NPC139891
hit id
C1259
🏥 Linked Health Topics
1 · diseases via target pathways📋 Clinical Trials
1 · subject of clinical studyNCT01848210 Efficacy and Safety of Coumarin and Troxerutin in the Symptomatic Treatment of C
→ Chronic Venous Insufficiency
📊 Meta-Analyses
1 · systematic reviewCRD42020223555 Associated factors of medication adherence employing coumarin derivatives or dir
→ Thrombosis is a mechanism for the development of d
📚 PubMed References
2 · cited researchPMID 32991865 Synergistic transport of a fluorescent coumarin probe marks coumarins as pharmac
Biochem Pharmacol
PMID 35177961 Comparison Between Hesperidin, Coumarin, and Deferoxamine Iron Chelation and Ant
Front Neurosci
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
ACTIVE — direct link via
target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables