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trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
Glycyrrhetinic acid
1
Clinical Trials
0
Meta-Analyses
8
PubMed References
Top Conditions Studied with Glycyrrhetinic acid
📋 Sample Trials
NCT03998982
Glycyrrhetinic Acid Combined With Dexamethasone in Management of Newly Diagnosed ITP
Unknown · Phase 4
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 30976491
Glycyrrhetinic acid binds to the conserved P-loop region and interferes with the interaction of RAS-effector proteins
Acta Pharm Sin B · 2019
PMID 28933787
Blocking autophagy enhances the apoptotic effect of 18β-glycyrrhetinic acid on human sarcoma cells via endoplasmic reticulum stress and JNK activation
Cell Death Dis · 2017
PMID 31830590
Dietary compound glycyrrhetinic acid suppresses tumor angiogenesis and growth by modulating antiangiogenic and proapoptotic pathways in vitro and in vivo
J Nutr Biochem · 2020
⚗️ All Ingredient data fields for Glycyrrhetinic acid
⚗️ Identity
Name
Glycyrrhetinic acid
Aliases / Synonyms
enoxolone; 471-53-4; Glycyrrhetic acid; Uralenic acid; 18-beta-Glycyrrhetinic acid; 18beta-Glycyrrhetinic acid; Rhetinic Acid; Glycyrrhetin; Biosone
🧪 Chemistry
Molecular Weight
470.6940
LogP
6.4126
Drug-likeness
0.464
H-Bond Acceptors
3
H-Bond Donors
2
Rotatable Bonds
1
🔬 Structures
Canonical SMILES
CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C
Isomeric SMILES
C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O
InChIKey
MPDGHEJMBKOTSU-YKLVYJNSSA-N
InChI
InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1
🔗 External References
🔍 Raw view — every non-empty column on this row (30 fields)
name
Glycyrrhetinic acid
common names
enoxolone; 471-53-4; Glycyrrhetic acid; Uralenic acid; 18-beta-Glycyrrhetinic acid; 18beta-Glycyrrhetinic acid; Rhetinic Acid; Glycyrrhetin; Biosone
herb ingredient id
HBIN028184
canonical smiles
CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C
isomeric smiles
C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O
inchi
InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1
inchikey
MPDGHEJMBKOTSU-YKLVYJNSSA-N
mol wt
470.6940
num h acceptors
3
num h donors
2
mol logp
6.4126
num rotatable bonds
1
drug likeness
0.464
cas id
471-53-4
tcmid ingredient id
23291; 8840
tcm id ingredient id
3939
pubchem cid
10114
npass id
NPC93503
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