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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Ingredient
44,598
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Gene Target
15,695
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Disease
30,467
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
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⚗️ Ingredient

Hyoscine

Open on HERB 2.0 ↗
5
Clinical Trials
3
Meta-Analyses
0
PubMed References
Top Conditions Studied with Hyoscine
Labor Pain 1 Labor 1 Shortening of active phase of labor 1 Office Hysteroscopy 1 Efficacy of Promethazine and Hyoscine in reducing the durati 1 Sialorrhea 1 Motion Sickness, Space|Motion Simulation|Parabolic Flight 1 Motion Sickness, Space|Motion Sickness|Sea Sickness 1
📋 Sample Trials
NCT01644838
Effect of Hyoscine and Promethazine on Labor Pain
Completed · Phase 2|Phase 3
NCT02613494
Clozapine-induced Hypersalivation - Feasibility Trial
Completed · Phase 1|Phase 2
NCT06056869
Effect of Hyoscine- Bromide on Duration of the First Stage of Labor
Recruiting
📊 Sample Meta-Analyses
CRD42020140048
Does hyoscine N-butylbromide facilitate in shortening the active phase of labor? A meta-analysis of randomization controlled trials .
Shortening of active phase of labor
CRD42021246658
Efficacy of hyoscine in pain management during hysteroscopy: a systematic review and meta-analysis
Office Hysteroscopy
CRD42021272783
The effectiveness of Hyoscine-promethazine on labor duration: a systematic review and meta-analysis of clinical trials
Efficacy of Promethazine and Hyoscine in reducing the duration of labor
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for Hyoscine
⚗️ Identity
Name
Hyoscine
Aliases / Synonyms
scopolamine; (-)-Hyoscine; 51-34-3; Scopine (-)-tropate; Scopine tropate; (-)-Scopolamine; Hyosol; 6,7-Epoxytropine tropate; Transderm-Scop
🧪 Chemistry
Molecular Weight
303.3580
LogP
0.9181
Drug-likeness
0.662
Oral Bioavailability
49.8400
H-Bond Acceptors
5
H-Bond Donors
1
Rotatable Bonds
4
🔬 Structures
Canonical SMILES
CN1C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4
Isomeric SMILES
CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4
InChIKey
STECJAGHUSJQJN-USLFZFAMSA-N
InChI
InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11?,12-,13-,14+,15-,16+/m1/s1
🔗 External References
HERB DB
HBIN029809 ↗
PubChem CID
3000322 ↗
CAS Number
138-12-5 ↗
NPASS
NPC287708
SymMap
817
TCMID
10869
TCMSP
MOL011519
🔍 Raw view — every non-empty column on this row (32 fields)
name
Hyoscine
common names
scopolamine; (-)-Hyoscine; 51-34-3; Scopine (-)-tropate; Scopine tropate; (-)-Scopolamine; Hyosol; 6,7-Epoxytropine tropate; Transderm-Scop
herb ingredient id
HBIN029809
canonical smiles
CN1C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4
isomeric smiles
CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4
inchi
InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11?,12-,13-,14+,15-,16+/m1/s1
inchikey
STECJAGHUSJQJN-USLFZFAMSA-N
mol wt
303.3580
num h acceptors
5
num h donors
1
mol logp
0.9181
num rotatable bonds
4
drug likeness
0.662
ob score
49.8400
cas id
138-12-5
symmap mol id
817
tcmid ingredient id
10869
tcmsp ingredient id
MOL011519
pubchem cid
3000322
npass id
NPC287708

🏥 Linked Health Topics

2 · diseases via target pathways
Sialorrhea
syndrome
Labor Pain
phenotype

📋 Clinical Trials

5 · subject of clinical study
NCT01644838 Effect of Hyoscine and Promethazine on Labor Pain
→ Labor Pain
NCT02613494 Clozapine-induced Hypersalivation - Feasibility Trial
→ Sialorrhea
NCT06056869 Effect of Hyoscine- Bromide on Duration of the First Stage of Labor
→ Labor
NCT05886660 Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-tra
→ Motion Sickness, Space|Motion Sickness|Sea Sicknes
NCT05852730 Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-tra
→ Motion Sickness, Space|Motion Simulation|Parabolic

📊 Meta-Analyses

3 · systematic review
CRD42020140048 Does hyoscine N-butylbromide facilitate in shortening the active phase of labor?
→ Shortening of active phase of labor
CRD42021246658 Efficacy of hyoscine in pain management during hysteroscopy: a systematic review
→ Office Hysteroscopy
CRD42021272783 The effectiveness of Hyoscine-promethazine on labor duration: a systematic revie
→ Efficacy of Promethazine and Hyoscine in reducing
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
  • Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
  • Target ↔ Disease: ACTIVE — direct link via target_health_topics
  • Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables