Relationship Graph Explorer
Follow the connections
Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.
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Herb
6,826
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⚗️
Ingredient
45,885
→
🧬
Gene Target
15,695
→
🏥
Disease
30,467
→
🧪
Evidence
23,241
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
🧬 Gene Target
MAPK1
0
Clinical Trials
0
Meta-Analyses
22
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 30503840
Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis
Pharmacol Res · 2019
PMID 23182854
Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells
Autophagy · 2013
PMID 33995019
How Aconiti Radix Cocta can Treat Gouty Arthritis Based on Systematic Pharmacology and UPLC-QTOF-MS/MS
Front Pharmacol · 2021
🧬 All Gene Target data fields for MAPK1
🧬 Identity
Gene Symbol
MAPK1
Gene Aliases
ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK
Protein Name
mitogen-activated protein kinase 1
Gene Type
protein-coding
TTD Target Type
Clinical Trial target
📍 Location
Organism
Homo sapiens
Taxonomy ID
9606
Chromosome
22
Map Location
22q11.22
🔗 External References
🔍 Raw view — every non-empty column on this row (28 fields)
name
MAPK1
gene symbol
MAPK1
gene alias name
ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK
protein name
mitogen-activated protein kinase 1
type of gene
protein-coding
ttd target type
Clinical Trial target
organism
Homo sapiens
taxonomy id
9606
map location
22q11.22
chromosome
22
entrez id
5594
omim id
176948
hgnc id
6871
ensembl id
ENSG00000100030
ttd id
T58970
target id str
HBTAR003192
tcmsp target id
354
🌿 Related Herbs
1 · contains this compound⚗️ Related Ingredients
3 · compounds in this herb🏥 Linked Health Topics
2 · diseases via target pathways📚 PubMed References
12 · cited researchPMID 30503840 Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351
Pharmacol Res
PMID 23182854 Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosi
Autophagy
PMID 33995019 How Aconiti Radix Cocta can Treat Gouty Arthritis Based on Systematic Pharmacolo
Front Pharmacol
PMID 33866197 Bioactive constituents and the molecular mechanism of Curcumae Rhizoma in the tr
Phytomedicine
PMID 34348126 Brown marine algae Gongolaria baccata extract protects Caco-2 cells from oxidati
Food Chem Toxicol
PMID 33995019 How Aconiti Radix Cocta can Treat Gouty Arthritis Based on Systematic Pharmacolo
Front Pharmacol
PMID 34899287 Exploring the Critical Components and Therapeutic Mechanisms of Perilla frutesce
Front Pharmacol
PMID 36332760 Studies on the metabolism and mechanism of acteoside in treating chronic glomeru
J Ethnopharmacol
PMID 33192531 Amygdalin Attenuates Atherosclerosis and Plays an Anti-Inflammatory Role in ApoE
Front Pharmacol
PMID 33959508 Apigenin Inhibits the Growth of Hepatocellular Carcinoma Cells by Affecting the
Front Oncol
PMID 35525528 Investigation of the mechanism of Isobavachalcone in treating rheumatoid arthrit
J Ethnopharmacol
PMID 35490492 Isoorientin attenuates doxorubicin-induced cardiac injury via the activation of
Phytomedicine
How to read these connections
Each box lists records connected to the one you are viewing, and says how the connection was made. A connection shows that two records are related in the source data. It does not show that something works, is safe or should be used, and a record with many connections is not necessarily better studied or more effective.
- Study records (trials, systematic reviews, publications): the study names this subject. Registered or ongoing studies have no results here, and animal or cell research does not show an effect in people.
- Source-database links (for example herb and compound, compound and gene target): taken from the imported databases and not independently checked by us.
- Name matches (for example formula and herb, or a condition named in a study): found by matching names, so they can be wrong. Treat them as leads, not findings.