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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Herb
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Ingredient
44,598
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Gene Target
15,695
→
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Disease
30,467
→
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
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⚗️ Ingredient

Uvadex

Open on HERB 2.0 ↗
8
Clinical Trials
0
Meta-Analyses
2
PubMed References
Top Conditions Studied with Uvadex
Graft-versus-Host Disease 2 Crohn's Disease 1 Crohn Disease 1 Sarcoma, Ewing|Sarcoma 1 Rheumatoid Arthritis 1 Patch/Plaque Stage Mycosis Fungoides 1 Cutaneous T Cell Lymphoma|Mycosis Fungoides 1
📋 Sample Trials
NCT00054600
Safety and Efficacy Study of Photopheresis With UVADEX to Prevent Graft-versus-Host Disease
Completed · Phase 2
NCT00054613
Safety and Efficacy Study of Photopheresis Plus Standard Therapy to Treat Chronic Graft-versus-Host Disease
Completed · Phase 2
NCT00056355
Extracorporeal Photopheresis to Maintain Symptoms Remission During Steroid Withdrawal in Patients With Steroid-Dependent Crohn's Disease
Completed · Phase 1
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32250498
Xanthotoxin and umbelliferone attenuate cognitive dysfunction in a streptozotocin-induced rat model of sporadic Alzheimer's disease: The role of JAK2/STAT3 and Nrf2/HO-1 signalling pathway modulation
Phytother Res · 2020
PMID 33579030
Mechanisms of the Procognitive Effects of Xanthotoxin and Umbelliferone on LPS-Induced Amnesia in Mice
Int J Mol Sci · 2021
⚗️ All Ingredient data fields for Uvadex
⚗️ Identity
Name
Uvadex
Aliases / Synonyms
methoxsalen; 8-Methoxypsoralen; 298-81-7; XANTHOTOXIN; Meladinine; Oxypsoralen; 8-MOP; 9-Methoxy-7H-furo[3,2-g]chromen-7-one; Oxsoralen; Xanthotoxine
🧪 Chemistry
Molecular Weight
216.1920
LogP
2.5478
Drug-likeness
0.586
Oral Bioavailability
35.2960
H-Bond Acceptors
4
Rotatable Bonds
1
🔬 Structures
Canonical SMILES
COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2
Isomeric SMILES
COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2
InChIKey
QXKHYNVANLEOEG-UHFFFAOYSA-N
InChI
InChI=1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
🔗 External References
HERB DB
HBIN047654 ↗
PubChem CID
4114 ↗
CAS Number
12692-94-3; 298-81-7 ↗
DrugBank
DB00553 ↗
NPASS
NPC33320
HIT
C0214
TCMID
22758; 29497
TCMSP
MOL001953
TCM-ID
93; 11425
🔍 Raw view — every non-empty column on this row (34 fields)
name
Uvadex
common names
methoxsalen; 8-Methoxypsoralen; 298-81-7; XANTHOTOXIN; Meladinine; Oxypsoralen; 8-MOP; 9-Methoxy-7H-furo[3,2-g]chromen-7-one; Oxsoralen; Xanthotoxine
herb ingredient id
HBIN047654
canonical smiles
COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2
isomeric smiles
COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2
inchi
InChI=1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
inchikey
QXKHYNVANLEOEG-UHFFFAOYSA-N
mol wt
216.1920
num h acceptors
4
num h donors
0
mol logp
2.5478
num rotatable bonds
1
drug likeness
0.586
ob score
35.2960
cas id
12692-94-3; 298-81-7
tcmid ingredient id
22758; 29497
tcmsp ingredient id
MOL001953
tcm id ingredient id
93; 11425
pubchem cid
4114
drugbank id
DB00553
npass id
NPC33320
hit id
C0214

🏥 Linked Health Topics

2 · diseases via target pathways
Rheumatoid Arthritis
syndrome
Crohn Disease
syndrome

📋 Clinical Trials

8 · subject of clinical study
NCT00054600 Safety and Efficacy Study of Photopheresis With UVADEX to Prevent Graft-versus-H
→ Graft-versus-Host Disease
NCT00054613 Safety and Efficacy Study of Photopheresis Plus Standard Therapy to Treat Chroni
→ Graft-versus-Host Disease
NCT00056355 Extracorporeal Photopheresis to Maintain Symptoms Remission During Steroid Withd
→ Crohn Disease
NCT00221000 Safety and Efficacy of Extracorporeal Photoimmune Therapy With UVADEX for the Tr
→ Rheumatoid Arthritis
NCT00221026 Safety and Efficacy of Extracorporeal Photoimmune Therapy With UVADEX for the Tr
→ Crohn's Disease
NCT00221039 Photopheresis as an Interventional Therapy for the Treatment of CTCL (Cutaneous
→ Cutaneous T Cell Lymphoma|Mycosis Fungoides
NCT01686594 PUVA Maintenance Therapy in Mycosis Fungoides
→ Patch/Plaque Stage Mycosis Fungoides
NCT03778996 SM-88 Maintenance Therapy for Advanced Ewing's Sarcoma and as Salvage Therapy fo
→ Sarcoma, Ewing|Sarcoma

📚 PubMed References

2 · cited research
PMID 32250498 Xanthotoxin and umbelliferone attenuate cognitive dysfunction in a streptozotoci
Phytother Res
PMID 33579030 Mechanisms of the Procognitive Effects of Xanthotoxin and Umbelliferone on LPS-I
Int J Mol Sci
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
  • Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
  • Target ↔ Disease: ACTIVE — direct link via target_health_topics
  • Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables