Relationship Graph Explorer
Follow the connections
Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.
🌿
Herb
6,826
→
⚗️
Ingredient
44,598
→
🧬
Gene Target
15,695
→
🏥
Disease
30,467
→
🧪
Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
28 Diseases matching "Alzheimer's disease"
Alzheimer'S Disease
Alzheimer'S Disease, Focal Onset
Presenile Dementia
Alzheimer Disease 7
Alzheimer Disease 5
Alzheimer Disease 2
Alzheimer Disease 9
Alzheimer Disease 4
Alzheimer Disease 18
Alzheimer Disease 12
Alzheimer Disease 14
Alzheimer Disease 19
Alzheimer Disease 10
Degenerative Brain Disorder
Alzheimer Disease, Late Onset
Prodromal Alzheimer'S Disease
Presenile And Senile Dementia
Alzheimer Disease, Early Onset
Alzheimer Disease, Familial, 1
Alzheimer Disease 6, Late-Onset
Familial Alzheimer Disease (Fad)
Acute Confusional Senile Dementia
Alzheimer Disease, Familial, Type 3
Alzheimer Disease 9, Susceptibility To
Familial Alzheimer'S Disease of Early Onset
Dementia Due To Alzheimer'S Disease (Disorder)
Alzheimer Disease, Familial, 3, With Spastic Parap
Alzheimer Disease, Familial, 3, With Spastic Parap
🏥 Disease / Health Topic
Alzheimer'S Disease
26
Clinical Trials
35
Meta-Analyses
0
PubMed References
📋 Sample Trials
NCT00010803
Ginkgo Biloba Prevention Trial in Older Individuals
Completed · Phase 3
NCT00164749
A Pilot Study of Curcumin and Ginkgo for Treating Alzheimer's Disease
Completed · Phase 1|Phase 2
NCT00814346
Effect of EGb761® on Brain Glucose Metabolism in Three Groups of Elderly Defined by Cognitive Functions
Completed · Phase 2
📊 Sample Meta-Analyses
CRD42019127560
Saffron for dementia and mild cognitive impairment: a systematic review and meta-analysis of randomized clinical trials
-Dementia (including Alzheimer's disease, vascular disease, Lewy body dementia,
CRD42021275439
A meta-analysis on the association of vitamin B, D, and E levels with the progression and risk of Alzheimer's disease
Alzheimer's Disease, neurodegenerative disease, vitamin deficiency, mitigating r
CRD42021275439
A meta-analysis on the association of vitamin B, D, and E levels with the progression and risk of Alzheimer's disease
Alzheimer's Disease, neurodegenerative disease, vitamin deficiency, mitigating r
📚 Sample References
None linked yet.
🏥 All Disease / Health Topic data fields for Alzheimer'S Disease
🏥 Names
Disease Name
Alzheimer'S Disease
Alias Names
Alzheimer'S Disease 8; Acute Confusional Senile Dementia; Alzheimer'S Disease 10; Alzheimer'S Disease 6; Alzheimer Disease, Late Onset; Late-Onset Form of Familial Alzheimer Disease; Dementia, Presenile; Alzheimer'S Disease 12; Alzheimer'S Disease; Alzheimer Disease; Alzheimer'S Disease 13; Alzheimer'S Disease 14; Alzheimer'S Disease 1; Alzheimer'S Disease 11; Alzheimer'S Disease 7; Alzheimer'S Disease, Focal Onset; Familial Alzheimer Disease (Fad); Alzheimer'S Disease 5; Alzheimer'S Disease, Un
Topic Type
syndrome
🧬 Ontology Classifications
DisGeNET Type
disease
UMLS Type
Disease or Syndrome
MeSH Class
Mental Disorders; Nervous System Diseases
HPO Class
Abnormality of the nervous system
DO Class
disease of anatomical entity; genetic disease
🔗 External References
HERB DB
MeSH
ICD-10
OMIM
HPO
Disease Ontology
110043; 110045; 110046; 1443; 10
DisGeNET
C0002395
🔍 Raw view — every non-empty column on this row (32 fields)
name
Alzheimer'S Disease
alias name
Alzheimer'S Disease 8; Acute Confusional Senile Dementia; Alzheimer'S Disease 10; Alzheimer'S Disease 6; Alzheimer Disease, Late Onset; Late-Onset Form of Familial Alzheimer Disease; Dementia, Presenile; Alzheimer'S Disease 12; Alzheimer'S Disease; Alzheimer Disease; Alzheimer'S Disease 13; Alzheimer'S Disease 14; Alzheimer'S Disease 1; Alzheimer'S Disease 11; Alzheimer'S Disease 7; Alzheimer'S Disease, Focal Onset; Familial Alzheimer Disease (Fad); Alzheimer'S Disease 5; Alzheimer'S Disease, Unspecified; Alzheimer'S Disease 2; Presenile And Senile Dementia; Alzheimer Disease, Early Onset; Cer
topic type
syndrome
disgenet disease type
disease
umls disease type
Disease or Syndrome
mesh disease class
Mental Disorders; Nervous System Diseases
hpo disease class
Abnormality of the nervous system
do disease class
disease of anatomical entity; genetic disease
umls disease type id
T047
mesh disease class id
F03; C10
hpo disease class id
HP:0000707
do disease class id
DOID:7; DOID:630
herb disease id
HBDIS000117
disgenet id
C0002395
mesh id
D000544
hpo id
HP:0002511
do id
110043; 110045; 110046; 1443; 10
icd10 id
G30.9; G30
omim id
104300
tcmsp disease id
51
🌿 Related Herbs
1 · contains this compound⚗️ Related Ingredients
20 · compounds in this herbQuercetin
PubChem CID 5280343
Beta-sitosterol
PubChem CID 222284
(+)-catechin
PubChem CID 9064
Delphinidin
PubChem CID 68245
Diosmetin
PubChem CID 5281612
Eriodictyol
PubChem CID 440735
Genkwanin
PubChem CID 5281617
Herbacetin
PubChem CID 5280544
Kaempferol
PubChem CID 5280863
(+)-leucocyanidin
PubChem CID 155206
Leucopelargonidin
PubChem CID 3286789
Luteolin
PubChem CID 5280445
Mandenol
PubChem CID 5282184
Naringenin
PubChem CID 439246
Pectolinarigenin
PubChem CID 5320438
Resivit
PubChem CID 445881
Stigmasterol
PubChem CID 5280794
Taxifolin
PubChem CID 439533
Truflex obp
PubChem CID 66540
Zinc03860434
PubChem CID 7057921
🧬 Gene / Protein Targets
9 · genes implicated in this diseaseCTSD
Gene CTSD
MPO
Gene MPO
Prostaglandin G/H synthase 2
Acetylcholinesterase
Muscarinic acetylcholine receptor M2
Muscarinic acetylcholine receptor M1
Amyloid beta A4 protein
Gamma-aminobutyric-acid receptor alpha-5 subunit
Neuronal acetylcholine receptor protein, alpha-7 chain
📋 Clinical Trials
12 · subject of clinical studyNCT00010803 Ginkgo Biloba Prevention Trial in Older Individuals
→ Dementia|Alzheimer's Disease
NCT00164749 A Pilot Study of Curcumin and Ginkgo for Treating Alzheimer's Disease
→ Alzheimer's Disease
NCT00814346 Effect of EGb761® on Brain Glucose Metabolism in Three Groups of Elderly Defined
→ Alzheimer's Disease|Cognitive Impairment
NCT00391833 Effect of Panax Ginseng on the Cognitive Performance in Alzheimer's Disease
→ Alzheimer's Disease|Memory Decline
NCT00164749 A Pilot Study of Curcumin and Ginkgo for Treating Alzheimer's Disease
→ Alzheimer's Disease
NCT00689637 Drug Interaction Study Between AZD3480 and Warfarin
→ Alzheimer's Disease
NCT00099710 Curcumin in Patients With Mild to Moderate Alzheimer's Disease
→ Alzheimer's Disease
NCT00082602 Safety and Tolerability Study of Extended Release (ER) Galantamine in Alzheimer'
→ Alzheimer's Disease
NCT00309725 A Cardiac Safety Study of Galantamine in the Treatment of Alzheimer's Disease.
→ Alzheimer's Disease
NCT00814801 An Efficacy and Safety Study of Galantamine for the Treatment of Patients With A
→ Alzheimer's Disease
NCT01054976 The Efficacy of Galantamine Treatment on Attention in Patients With Alzheimer's
→ Alzheimer's Disease
NCT01478633 Evaluation of Efficacy and Safety of Galantamine in Patients With Dementia of Al
→ Alzheimer's Disease
📊 Meta-Analyses
12 · systematic reviewCRD42019127560 Saffron for dementia and mild cognitive impairment: a systematic review and meta
→ -Dementia (including Alzheimer's disease, vascular
CRD42021275439 A meta-analysis on the association of vitamin B, D, and E levels with the progre
→ Alzheimer's Disease, neurodegenerative disease, vi
CRD42021275439 A meta-analysis on the association of vitamin B, D, and E levels with the progre
→ Alzheimer's Disease, neurodegenerative disease, vi
CRD42020210179 Efficacy of butylphthalide combined with oxiracetam in the treatment of vascular
→ Vascular cognitive impairment is the second most c
CRD42021268819 What is new about the relationship between copper dyshomeostasis and Alzheimer’s
→ Relationship between copper and Parkinson's or cop
CRD42021283692 The potential diagnostic accuracy of endogenous formaldehyde in Alzheimer's
→ Alzheimer's disease (AD) is a neurodegenerative di
CRD42018109231 Donepezil, galantamine, rivastigmine and memantine for Alzheimer's disease:
→ Alzheimer's disease.
CRD42015024796 Huperzine A for major depressive disorder: a review of the literature
→ Huperzine A, an alkaloid initially identified from
CRD42015024796 Huperzine A for major depressive disorder: a review of the literature
→ Huperzine A, an alkaloid initially identified from
CRD42015024796 Huperzine A for major depressive disorder: a review of the literature
→ Huperzine A, an alkaloid initially identified from
CRD42015024198 Huperzine A for cognitive deficits in schizophrenia: a systematic review and met
→ Huperzine A, an alkaloid initially identified from
CRD42015024198 Huperzine A for cognitive deficits in schizophrenia: a systematic review and met
→ Huperzine A, an alkaloid initially identified from
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
ACTIVE — direct link via
target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables