Supervised-Service Frameworks (Oregon, Colorado and Others)
How Oregon's licensed psilocybin services and Colorado's natural medicine program are set up, what New Mexico plans, and why none of this equals medical approval.
Content last updated . This page has not been medically reviewed.
This page describes state programs in the United States, using the states' own pages read on 2026-10-22. It is not legal advice, not a recommendation to use any substance, and not a directory of providers. Laws and rules change. The state pages we read did not discuss federal law, and the federal regulation we read still lists psilocybin in Schedule I. [1] We do not say how the two interact; speak with a lawyer about your situation.
If you or someone near you is in crisis, call or text 988 (US) or call 911.
What a "supervised-service framework" is
A supervised-service framework is a state law that lets licensed businesses and licensed practitioners provide defined psilocybin services under state rules. It is different from a clinical trial, from an FDA-approved prescription medicine and from decriminalization. See decriminalization vs legalization and medical approval.Oregon (psilocybin services)
Oregon's Health Authority says its program implements Ballot Measure 109 (passed November 2020, now in ORS 475A), which directs the agency to license and regulate manufacture, transportation, delivery, sale and purchase of psilocybin products and the provision of psilocybin services. [2]What the agency says about the structure:
- Three kinds of session. Services mean preparation, administration and integration sessions provided by a licensed facilitator. [3]
- Where. The administration session happens at a licensed service center, and the agency says that session is the only time a client may purchase and consume psilocybin products. [3]
- Who. A client must be 21 or older. A prescription or medical referral is not required. A client need not live in Oregon. [3]
- Screening. A client may be found ineligible if they are experiencing ideation of harm to self or others, have taken lithium within 30 days, or have been diagnosed with active psychosis at any time. [3]
- Choice stays with the facilitator. Licensed facilitators may decline services to clients for any reason. [3]
- Cost. The agency says it does not set or regulate prices. [3]
This is a regulated service model, not a medical treatment pathway. The agency page we read did not describe the program as a medical treatment or make claims about treating conditions. [2] For how we think about informed consent and boundaries in this kind of setting, see informed consent in psychedelic care and professional boundaries in psychedelic care.
Colorado (natural medicine)
Colorado's Natural Medicine Division says Colorado legalized psilocybin mushrooms for personal use or use by healing centers after a law was signed in May 2023. [4] The Department of Revenue licenses and regulates natural medicine businesses (healing centers, cultivations, manufacturers and testing facilities), while the Department of Regulatory Agencies licenses facilitators. [4] The same page says the sale of any natural medicine is prohibited under the law, and it lists rules against misusing Indigenous names and imagery in marketing. [4]We do not describe the personal-use rules or any production details here. Read the state's page directly for the current rules, since the division notes that rulemaking continues. [4]
New Mexico (medical psilocybin, in development)
New Mexico's Department of Health says a law signed in April 2025 establishes a regulated program for medical use of psilocybin for qualified conditions, naming examples such as major treatment-resistant depression, PTSD, substance use disorders and end-of-life care. [5] The page says the program is set to be implemented by December 31, 2026, and that the department was developing rules, treatment protocols and training requirements. [5] We have no evidence from the page that services are operating.Other places
We did not read official pages for other states or countries this session, so we do not describe frameworks elsewhere. Proper evidence not found for those here; see how law differs by country.What a license does not show
- It does not show that a substance is safe or effective for any condition; see psychedelic adverse effects and contraindications.
- It does not replace a doctor's advice about your medicines. Do not stop or change a prescription because of a service.
- It does not mean every provider claim is true; see evaluating clinic claims.
Frequently asked questions
Is Oregon's program medical treatment?
The agency describes licensed psilocybin services, and says no prescription or medical referral is required. [3] We would not call it an approved medical treatment.
Do you need to live in Oregon to use the services?
Per the agency, no. [3] Eligibility still depends on screening, and facilitators can decline. [3]
How is Colorado's program organized?
Two state departments split the work: one licenses the businesses and one licenses facilitators. [4]
Is New Mexico's program running?
The state page we read says the program is set to be implemented by December 31, 2026 and that rulemaking was under way. [5] Check the department for current status.
Does a state license mean the substance is federally legal?
The federal regulation we read lists psilocybin in Schedule I. [1] The state pages did not address federal law. This is not legal advice.