modern wellness · Symptom

Fatigue

🩺 HPO Source

HPO ID

HP:0012378 ↗

HPO Label

Fatigue

HPO Definition

A subjective feeling of tiredness characterized by a lack of energy and motivation.

HPO Curator Comment

Fatigue is distinct from muscle weakness.

🔤 Synonyms (3)

Synonyms

FatigueTiredTiredness

🔗 Cross-References (3)

SNOMEDCT_US248274002

SNOMEDCT_US84229001

UMLSC0015672

🔼 Broader Terms (1)

HP:0025142Constitutional symptom

🏥 Conditions where Fatigue appears

40 · bridged via HPO ↔ OMIM

syndrome OMIM 302060

3-Methylglutaconic Aciduria Type 2

freq: 1/1 ev: PCS

syndrome OMIM 615954

Acth-Independent Macronodular Adrenal Hyperplasia 2

phenotype OMIM 616000

Analbuminemia

freq: 2/2 ev: PCS

syndrome OMIM 233450

Anti-Glomerular Basement Membrane Disease

freq: 19/29 ev: PCS

syndrome OMIM 616050

Autoinflammation With Infantile Enterocolitis

freq: 1/1 ev: PCS

syndrome OMIM 181350

Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (Disorder)

freq: 7/7 ev: PCS

syndrome OMIM 614162

Candidiasis, Familial, 7

Cataract And Cardiomyopathy

ev: TAS

syndrome OMIM 607426

Coenzyme Q10 Deficiency, Primary, 1

ev: IEA

syndrome OMIM 616794

Combined Oxidative Phosphorylation Deficiency 28

ev: PCS

syndrome OMIM 617713

Combined Oxidative Phosphorylation Deficiency 33

freq: 1/4 ev: PCS

syndrome OMIM 611489

Corticosteroid-Binding Globulin Deficiency

ev: IEA

syndrome OMIM 611489

Corticosteroid-Binding Globulin, Elevated

ev: IEA

phenotype OMIM 123320

Creatine Phosphokinase Serum Increased

ev: PCS

syndrome OMIM 617186

Encephalopathy, Progressive, Early-Onset, With Brain Edema And/Or Leukoencephalopathy

freq: 1/6 ev: PCS

syndrome OMIM 600204

Epiphyseal Dysplasia, Multiple, 2

freq: 2/4 ev: PCS

syndrome OMIM 133100

Erythrocytosis Familial, 1

ev: TAS

syndrome OMIM 263400

Erythrocytosis, Familial, 2

ev: TAS

syndrome OMIM 120100

Familial Cold Autoinflammatory Syndrome 1

ev: PCS

syndrome OMIM 120100

Familial Cold Urticaria

Glucocorticoid Receptor Deficiency

ev: TAS

syndrome OMIM 611556

Glycogen Storage Disease 0, Muscle

freq: 1/1 ev: PCS

syndrome OMIM 306000

Glycogen Storage Disease Ixa1

freq: 3/15 ev: PCS

syndrome OMIM 614921

Glycogen Storage Disease Xiv

freq: 3/13 ev: PCS

syndrome OMIM 306000

Glycogen Storage Disease, Type Ixa2

freq: 3/15 ev: PCS

syndrome OMIM 608710

Granulomatosis With Polyangiitis

ev: PCS

syndrome OMIM 604250

Hemochromatosis, Type 3

ev: TAS

syndrome OMIM 606069

Hemochromatosis, Type 4

freq: 2/20 ev: PCS

syndrome OMIM 600740

Hypocalciuric Hypercalcemia, Familial, Type Iii

freq: HP:0040283 ev: TAS

Immunodeficiency, Common Variable, 11

Macrocephaly, Alopecia, Cutis Laxa, And Scoliosis

freq: 3/3 ev: PCS

syndrome OMIM 616355

Mental Retardation, Autosomal Dominant 35

freq: 2/11 ev: PCS

syndrome OMIM 617061

Mental Retardation, Autosomal Dominant 44

freq: 3/4 ev: PCS

syndrome OMIM 618250

Mitochondrial Complex I Deficiency, Nuclear Type 29

freq: 1/3 ev: PCS

📜 Formulas studied for Fatigue

24 · text-bridged via indications + syndromes

E Jiao Bu Xue Granule

E Jiao Bu Xue Ke Li

Cough, Consumptive disease, Blood fatigue

E Jiao Dang Gui Mixture

E Jiao Dang Gui He Ji

Amenorrhea, Blood fatigue, Menstrual irregularities

E Jiao Granule

E Jiao Ke Li

Flooding and spotting, Hematochezia, Hemoptysis, Threatened abortion, Hematemesis, Consumptive disease, Blood fatigue, Menstrual irregularities

E Jiao Sheng Hua Electuary

E Jiao Sheng Hua Gao

Oligogalactia, Blood-wind fatigue

E Gui Yang Xue Oral Liquid

E Gui Yang Xue Kou Fu Ye

Deficiency of qi and blood, pale complexion, dizziness and fatigue, muscle wasting, amenorrhea, red vaginal discharge

An Shen Syrup

An Shen Tang Jiang

Inability to sleep, Dizziness, Blood fatigue

Ba Zhen Dai Medicinal Tea

Ba Zhen Dai Pao Cha

Blood fatigue, Profuse menstruation

Bi Qi Capsule; Biqi Capsule

Biqi Jiaonang

Used for insufficient blood, rheumatism, sore muscles and joints, joint swelling, stiffness and deformation or muscle atrophy, shortness of breath and fatigue; rheumatism, rheumatoid arthritis, lumbar

Biantong Capsule; Bian Tong Capsule

Biantong Jiaonang

Used for constipation caused by spleen and kidney deficiency, intestinal qi stagnation, symptoms: constipation or fatigue, shortness of breath, dizziness, waist and knee weakness; habitual constipatio

Bian Tong Tablet; Biantong Tablet

Biantong Pian

Bu Xin Qi Oral Liquid; Buxinqi Oral Liquid

BuxinqiKoufuye

Used for shortness of breath, heart palpitations, fatigue, dizziness and heart-qi deficiency type chest pain and heartache

Bu Xue Dang Gui Jing

Dizziness, Blood fatigue, Menstrual irregularities

Bu Xue Tiao Jing Tablet

Bu Xue Tiao Jing Pian

Flooding and spotting, Amenorrhea, Leukorrheal diseases, Dysmenorrhea, Blood fatigue

Buzhong Yiqi Granule; Bu Zhong Yi Qi Granule

BuzhongYiqiKe Li

Used for diarrhea, prolapse of the anus, vaginal arrhythmia caused by weakness of the spleen and stomach, depression of the qi, symptoms such as fatigue, lack of food, abdominal distension, loose stoo

Shen Jing Zhi Ke Pill; Shenjing Zhike Pill

Shenjing Zhike Wan

Used for diminishing thirst caused by deficiency of both qi and yin and internal heat and body fluid injury. Symptoms: lack of energy, fatigue, dry mouth and polydipsia, easy hunger, weight loss; type

Shen Ling Bai Zhu Powder; Shenling Baizhu Powder

Shenling Baizhu San

Used for weak spleen and stomach, lack of food, loose stools, shortness of breath and coughing, fatigue and weakness of limbs

Shen Lu Fu Zheng Capsule

Shen Lu Fu Zheng Jiao Nang

Deficiency of yin and yang caused by fatigue, dizziness, tinnitus, forgetfulness, insomnia, waist and knee pain, impotence and premature ejaculation, frequent nocturia and adjuvant treatment of cancer

Shen Qi Shou Wu Bu Zhi

Consumptive disease, Blood-wind fatigue

Shen Qi Wu Wei Zi Capsule; Shenqi Wuweizi Capsule

Shenqi Wuweizi Jiaonang

Used for insomnia, dreaminess, forgetfulness, fatigue, palpitations, shortness of breath, spontaneous sweating caused by insufficient blood and heart and spleen

Shenrong Guben Tablet; Shen Rong Gu Ben Tablet

Shenrong Guben Pian

It is used for limb fatigue, pale complexion, tinnitus and dizziness caused by deficiency of both qi and blood

Bu Pi An Shen Mixture

Bu Pi An Shen He Ji

Deficiency of the heart and spleen, shortness of breath and palpitations, insomnia, dreaminess, dizziness, dizziness, fatigue, loss of appetite, uterine bleeding and blood in the stool

Shen Su Pill; Shensu Pill

Shensu Wan

Used for colds caused by physical weakness, feeling cold, symptomatic symptoms such as chills and fever, headache and stuffy nose, coughing and sputum, chest tightness, vomiting, fatigue, shortness of

Shen Wu Jian Nao Capsule; Shenwu Jiannao Capsule

Shenwu Jiannao Jiaonang

Used for mental exhaustion, insomnia, dreaminess, dizziness, fatigue, weakness, and memory loss caused by insufficient kidney essence and liver qi and blood deficiency

Bu Shen Jian Pi Oral Liquid

Bu Shen Jian Pi Kou Fu Ye

Deficiency of the spleen and stomach due to insufficient kidney yang, sore waist and soft knees, cold form and lack of warmth, physical weakness and fatigue, full abdominal distension, loss of appetit

🔗 Knowledge Graph Connections

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Real research connections from HERB 2.0, TCMSP, and clinical evidence sources. 4 related entities shown — click any to follow the trail.

🧬 Gene targets implicated · 1

Cytochrome P450 1A2

🧪 Compounds reaching those targets · 2

🌿 Herbs studied for this · 1

Ephedra

Ma Huang