natural remedies · Ingredient
Quercetin
Formula: C15H10O7 · MW: 302.238 · Drug-likeness: 0.434
⚗️ Identity
Name
Quercetin
Aliases / Synonyms
117-39-5; Sophoretin; Meletin; Quercetine; Xanthaurine; Quercetol; Quertine; Quercitin; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
🧪 Chemistry
Molecular Weight
302.2380
LogP
1.9880
Drug-likeness
0.434
H-Bond Acceptors
7
H-Bond Donors
5
Rotatable Bonds
1
🔗 External References
31
Clinical Trials
30
Meta-Analyses
100
PubMed References
Top Conditions Studied with Quercetin
Covid-19 5
Aging 2
Covid19 2
Chronic Obstructive Pulmonary Disease 2
Endometriosis 1
oxidative stress 1
Sarcoidosis 1
Diabetes Mellitus, Type 2 1
On August 24, 2021, the Lancet released the first comprehens 1
Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Sta 1
Pharmacokinetics 1
This review will examine the analgesic effects of quercetin 1
📋 Sample Trials
NCT01912820
Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Cancer Undergoing Surgery
Completed · Phase 1 · Adenocarcinoma of the Prostate|Recurrent
NCT05008003
Vit D3 for Early Symptoms of COVID-19
Unknown · Covid19
NCT01691404
Study on the Effects of Epicatechin and Quercetin Supplementation on Vascular Function and Blood Pressure (FLAVO)
Completed · Hypertension|Endothelial Dysfunction
NCT04468139
The Study of Quadruple Therapy Zinc, Quercetin, Bromelain and Vitamin C on the Clinical Outcomes of Patients Infected With COVID-19
Unknown · Phase 4 · Covid-19
NCT00065676
Investigating the Use of Quercetin on Glucose Absorption in Obesity, and Obesity With Type 2 Diabetes
Completed · Phase 2 · Obesity|Diabetes
NCT00402623
The Effect of Quercetin in Sarcoidosis
Completed · Sarcoidosis
📊 Sample Meta-Analyses
CRD42021273276
Quercetin as a potential therapeutic and prophylactic agent for COVID-19: a systematic review of clinical evidence
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a high
CRD42021239852
systematic evaluation and meta-analysis of quercetin against hepatic fibrosis in animal models
CRD42022374228
Clinical outcomes of quercetin for COVID-19 patients: systematic literature review and meta-analysis
In previous studies, quercetin has been shown to have anti-inflammatory and anti
CRD42022383491
Mechanism of action of quercetin in rheumatoid arthritis models: Meta-analysis and systematic review of animal studies
CRD42023389949
The effect of quercetin supplementation on cardiometabolic outcomes: an umbrella review of meta-analysis of data from randomized controlled trials
Effect of quercetin intervention on lipid profile, glucose control indices, bloo
CRD42023391219
Effects of quercetin on outcomes of covid-19 patients: a systematic review and meta-analysis
COVID-19
📚 Sample References
PMID 31497913
Quercetin protects against cisplatin-induced acute kidney injury by inhibiting Mincle/Syk/NF-κB signaling maintained macrophage inflammation
Phytother Res · 2020
PMID 31672514
Quercetin as a Lyn kinase inhibitor inhibits IgE-mediated allergic conjunctivitis
Food Chem Toxicol · 2020
PMID 31804760
Quercetin alleviates lipopolysaccharide-induced inflammatory responses by up-regulation miR-124 in human renal tubular epithelial cell line HK-2
Biofactors · 2020
PMID 32000299
Quercetin protects against diabetic encephalopathy via SIRT1/NLRP3 pathway in db/db mice
J Cell Mol Med · 2020
PMID 32009956
Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats via Regulating BDNF-Related Imbalance of Copine 6 and TREM1/2 in the Hippocampus and PFC
Front Pharmacol · 2020
PMID 32357395
Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats
Pharmaceutics · 2020
🏥 Linked Health Topics 7 · matched via study conditions
🔗 Knowledge Graph Connections
Open full graph →Real research connections from HERB 2.0, TCMSP, and clinical evidence sources. 25 related entities shown — click any to follow the trail.
🌿 Herbs containing this compound · 1
🧬 Gene targets · 12
Prostaglandin G/H synthase 2
binding 0.880
Thrombin
binding 0.871
Heat shock protein HSP 90
binding 0.843
Trypsin-1
binding 0.838
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform
binding 0.834
Retinoic acid receptor RXR-alpha
binding 0.818
AR
AR
binding 0.814
Nitric-oxide synthase, endothelial
binding 0.813
Gamma-aminobutyric acid receptor subunit alpha-1
binding 0.810
Prostaglandin G/H synthase 1
binding 0.809
Aldose reductase
binding 0.801
PPARG
PPARG
binding 0.796
🏥 Linked health topics · 12
Abdominal aortic aneurysm
disease
Abortion, Spontaneous
disease
Acne
syndrome
Acute coronary syndromes
disease
Acute Promyelocytic Leukemia
disease
Adenomatous polyposis
disease
Adrenocorticotrophic hormone-secreting pituitary tumors
disease
Adult respiratory distress syndrome
disease
African Trypanosomiasis
syndrome
Allergic airway inflammation
disease
Allergic diseases
disease
Allergic rhinitis, unspecified
disease