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THERAPIES & TRADITIONS · GUIDE

Kampo Medicine

Kampo is Japan's traditional herbal medicine, mostly prescribed by physicians and covered by national insurance. How it differs from Chinese medicine, what research shows and its risks.

Content last updated . This page has not been medically reviewed.

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What Kampo is

Kampo is Japan's traditional herbal medicine system. A 2020 review calls it a unique Japanese system derived from traditional Chinese herbal medicine. [1] The word itself literally means "method from the Han period" of ancient China, which points to its origin. [2] In Japan it sits inside mainstream health care: patients can receive Western and Kampo medical care at the same time in the same medical institution. [1]

This page is an overview. Five companion guides cover the history of Kampo, Kampo concepts such as sho, formulas and extract granules, insurance and regulation and daikenchuto research. This site gives information only, not medical advice.

Origins in brief

One review dates the first introduction of Chinese herbal medicine to Japan at 552 AD. [1] Kampo's specific Japanese character took shape during the Edo period, from 1600 onward, as Japan's seclusion widened the gap with Chinese theory. [2] After the Meiji Restoration of 1868 the government adopted the German system of medical education and excluded Kampo as pre-modern, and Kampo did not regain official attention until around 1970. [1] The full story is in History of Kampo.

How Kampo differs from Traditional Chinese Medicine

Kampo has Chinese roots but is its own Japanese tradition, so this site treats it separately from Traditional Chinese Medicine. A 2011 review says TCM emphasizes Yin and Yang and the five elements, while Japanese Kampo favors diagnostic methods that relate symptoms directly to the therapy. [2] Kampo does still use Yin-You (yin-yang) among its basic concepts, according to a 2020 review. [1] Within each tradition there have been many schools, and disputes among them are common. [3] A side-by-side view is in Kampo, Hanbang and Chinese medicine compared.

How it is practiced today

Japan lists 148 Kampo prescriptions for national insurance funding, and extract preparations make up up to 95 percent of the Japanese Kampo market. [2] A 2023 review reports that more than 80 percent of Japanese physicians prescribe traditional medicine, especially in primary care. [4] Even so, in 2009 insurance claims, Kampo drugs were prescribed for only 1.34 percent of all patients. [5] Details are in formulas and extract granules.

Core ideas, as traditional frameworks

A Kampo diagnosis, called sho, is a traditional framework built from history taking, abdominal palpation, tongue inspection and pulse diagnosis. [2] Sho and related ideas such as ki, ketsu and sui are not tested biomedical mechanisms. The 2020 review also cautions that it is risky to use Kampo or Chinese formulas outside the context of Kampo's own diagnostic paradigm. [1] This site gives no self-diagnosis tools. See Kampo concepts.

What research shows

A 2011 review included 135 studies of Kampo formulas: about half used a standard control and 28 a placebo control. [2] Two thirds of them enrolled fewer than 100 people and the overall methodological quality appeared low, and none used Kampo diagnosis as the basis for treatment. [2]
4 findings · 1 supported · 3 limited or unclearThe colour follows the evidence label on each card.
  1. Kampo trials overall (to 2009)

    Insufficient evidence for most uses

    Many small trials of low overall quality. [2]

  2. Daikenchuto after abdominal cancer surgery

    Promising but limited

    A 2025 meta-analysis of 11 randomized trials found a modest improvement in time to first flatus. [6]

  3. Pain

    Insufficient evidence from the sources read

    A 2020 narrative review describes Kampo use for several pain conditions; it does not grade the evidence. [1]

  4. Sho and qi-type concepts

    Traditional use only

    Not tested as biomedical mechanisms.

Results for one formula do not carry over to another. Read daikenchuto trials and historical use vs clinical evidence.

Buying outside Japan

In the United States the FDA regulates dietary supplements under a different set of rules than drugs, and has authority to act against an adulterated or misbranded supplement after it reaches the market. [9] A 2026 report on one US distributor found its top five Kampo formulations differ from those most prescribed in Japan. [10] Do not assume an imported product matches a Japanese prescription formula.

Who should seek conventional care first

See a clinician first for sudden, severe or worsening symptoms, pregnancy, liver or kidney disease, and for children. Do not stop a prescribed medicine because of any herbal product. NCCIH advises telling all your health care providers about the approaches you use. [11]

Related pages

Compare Traditional Korean Medicine, read about Chinese herbal medicine and return to Traditional Healing Systems.

Frequently asked questions

Is Kampo the same as Chinese herbal medicine?

No. It derives from Chinese herbal medicine but developed as a Japanese system, and today is mostly standardized extracts prescribed by physicians. [1][2]

Is Kampo covered by insurance in Japan?

Yes. 148 Kampo prescriptions can be funded within the national health insurance drug list. [2]

Does Kampo work?

It depends on the formula and the condition. Many trials exist, but the 2011 review found most were small and of low overall quality. [2]

Can Kampo cause side effects?

Yes. Liver injury, lung injury and a licorice-related condition called pseudoaldosteronism have been reported. [1]

Can I buy Kampo outside Japan?

In the United States the FDA can act against an adulterated or misbranded supplement after it reaches the market, so ask a clinician or pharmacist before buying any herbal product. [9]

More details: evidence, limits and cautions

The details behind this page: cautions, limits of the evidence and where sources disagree. Open any note to read it.

Safety
Kampo extracts are herbal drugs and can cause serious reactions. A review cited in the 2020 pain paper found that the most frequent reported events were liver injury (28.2 percent), lung injury (27.8 percent) and pseudoaldosteronism (21.0 percent), a licorice-related problem with fluid retention, low potassium and high blood pressure. [1] Licorice root is in 109 of 148 prescription Kampo extract formulas. [1]

Herbs and medicines can interact in harmful ways. [7] The NHS says people should not take herbal medicines if pregnant or breastfeeding or if they have kidney or liver problems, and that they are not recommended for children. [8] Ask a clinician or pharmacist before combining any herbal product with a prescription. See medication interactions.

References
  1. Arai Y-C and others. Kampo for the Treatment of Pain in Japan: A Review. Pain and Therapy 2020. Read 2026-10-22.
  2. Watanabe K and others. Traditional Japanese Kampo Medicine: Clinical Research between Modernity and Traditional Medicine. Evidence-Based Complementary and Alternative Medicine 2011. Read 2026-10-22.
  3. Terasawa K. Evidence-based Reconstruction of Kampo Medicine: Part II, The Concept of Sho. Evidence-Based Complementary and Alternative Medicine 2004. Read 2026-10-22.
  4. Yoshino T and others. The Integration of Traditional Medicine with Conventional Biomedicine: A Narrative Review of the Japanese Perspective. Journal of Integrative and Complementary Medicine 2023. Read 2026-10-22.
  5. Katayama K and others. Prescription of Kampo drugs in the Japanese health care insurance program. Evidence-Based Complementary and Alternative Medicine 2013. Read 2026-10-22.
  6. Kogo H and others. Is daikenchuto effective for postoperative intestinal dysfunction after gastroenterological cancer surgery? An updated meta-analysis. International Journal of Clinical Oncology 2025. PubMed 40820043 (abstract). Read 2026-10-22.
  7. NCCIH (US). 6 Tips: How Herbs Can Interact With Medicines. Read 2026-10-22.
  8. NHS (UK). Herbal medicines and complementary therapies. Read 2026-10-22.
  9. US Food and Drug Administration. Dietary Supplements. Read 2026-10-22.
  10. Williams NL and others. Reported distribution patterns of five Kampo formulations in the United States. Global Advances in Integrative Medicine and Health 2026. PubMed 42724176 (abstract). Read 2026-10-22.
  11. NCCIH (US). 6 Things To Know When Selecting a Complementary Health Practitioner. Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.