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Triphala: Traditional Use, Research and Safety

Triphala is a classical three-fruit Ayurvedic formulation; this guide separates traditional use from what trials of lipids, glucose and mouthwash found, with safety and quality notes.

Content last updated . This page has not been medically reviewed.

What triphala is

Triphala is a classical Ayurvedic formulation made from the fruits of three plants: amalaki (Emblica officinalis, also called Phyllanthus emblica), bibhitaki (Terminalia bellerica) and haritaki (Terminalia chebula). [1] Its name is commonly translated as "three fruits." In Ayurveda it is described as a cornerstone of digestive and "rejuvenative" treatment. [1] That is a traditional description, not a tested result. This page gives no doses, recipes or preparation steps.

Traditional use and what research measured are different things

Ayurvedic texts and practitioners describe triphala in the terms of the tradition. Researchers ask narrower questions: in a defined group of people, did a specific product change a measured outcome compared with a placebo or another treatment? Labels used below: promising but limited, mixed, insufficient evidence, preclinical, traditional use only.

One caution about the literature itself. A 2017 review of triphala's uses was written by authors linked to the Chopra Foundation, which partly funded one author. [1] Reviews that list many possible effects often rely on laboratory and animal work, so look for trials in people.

What the evidence shows, use by use

UseWhat the source foundLabel
Cholesterol, blood sugar, weightA systematic review of 12 randomized trials (749 patients) found lower LDL cholesterol, total cholesterol and triglycerides in 6 studies, lower weight measures in 5, and lower fasting glucose in people with diabetes but not without it. The authors said large, well-designed trials are needed. [2]promising but limited
Cholesterol (guggulu plus triphala together)A placebo-controlled trial of 90 adults with high cholesterol found the combination no better than placebo for total or LDL cholesterol, BMI or waist size after 3 months. [3]no benefit shown in this trial
Gum inflammation (mouthwash, not swallowed)A meta-analysis of 7 trials found triphala mouthwash comparable to chlorhexidine mouthwash for plaque-related gum inflammation, but results varied a great deal between trials. [4]promising but limited
Post-COVID-19 conditionIn a preliminary trial of 74 people, some blood markers moved within the triphala group, but there was no statistically significant difference between triphala and placebo on the main outcomes. [5]insufficient evidence
Constipation and bowel regularityThe 2017 review lists laxative action among triphala's described effects. [1] I did not find a systematic review of constipation trials to read.Proper evidence not found (checked PubMed reviews on triphala)
Gut bacteria, antioxidant, anti-inflammatory and other effectsReported in laboratory work and in the 2017 review. [1]preclinical

Read the first row with care: the review authors concluded the benefit is only possible "under certain conditions" and not confirmed. [2]

Safety, quality and interactions

  • Side effects in trials. The lipid and glucose review reported no serious adverse events linked to triphala. [2] In the guggulu plus triphala trial, 2 of 46 people in the treatment group developed a hypersensitivity rash and none on placebo. [3] Those trials were short, so long-term safety is not established.
  • Product quality. Surveys of Ayurvedic products sold in the United States found lead, mercury or arsenic in about one in five, and these reports were about Ayurvedic products in general, not triphala specifically. [6] The National Center for Complementary and Integrative Health (NCCIH) says some Ayurvedic preparations may contain these metals in amounts that can be toxic. [7] Triphala sold as a US dietary supplement is not approved by the FDA before sale. [8]
  • Pregnancy, breastfeeding, children and medicines. NCCIH advises pregnant or nursing people to check with a health care provider because some Ayurvedic products could be harmful. [7] Ask a clinician or pharmacist before combining triphala with prescribed medicines, especially if you take several.
  • Medicines handled by liver enzymes. Memorial Sloan Kettering says triphala inhibits two liver enzymes (CYP3A4 and CYP2D6) and advises against taking it with medicines those enzymes clear, because side effects may be more likely. [9]
  • Blood sugar and surgery. The trial review above found lower fasting glucose in people with diabetes, [2] and a supplement monograph on Terminalia (the genus of two of the three fruits) says it may lower blood sugar, may need diabetes-medicine adjustment, and advises stopping it at least 2 weeks before planned surgery. [10] Tell your prescriber and surgical team. See supplements and diabetes and supplements before surgery.
  • Pregnancy and breastfeeding. The same monograph advises avoiding Terminalia species in pregnancy and breastfeeding because safety is unknown or reliable data are lacking. [10]
  • Do not use it to delay care. NCCIH advises against using Ayurvedic medicine to postpone seeing a conventional provider about a medical problem. [7]

Where it fits

If your goal is digestion, see Ayurveda for digestion, IBS and constipation. For cholesterol, see Ayurveda for blood pressure and cholesterol, and for the herb-by-herb map, Ayurvedic ingredients and where to find each guide. The forms triphala is sold in are explained in Ayurvedic herbal preparations. Lead and other metal concerns are covered in Ayurvedic products: heavy metals and product quality. The related resin-based formulations are in guggulu formulations.

Frequently asked questions

What is in triphala?

Three dried fruits: amalaki, bibhitaki and haritaki, from Emblica officinalis (Phyllanthus emblica), Terminalia bellerica and Terminalia chebula. [1] Brands can differ, so read the label.

Does triphala lower cholesterol or blood sugar?

A systematic review of 12 trials suggested it might, under certain conditions, but called for larger, better trials. [2] A separate placebo-controlled trial of guggulu plus triphala found no benefit over placebo for cholesterol. [3] Evidence is promising but limited and mixed.

Is triphala proven as a laxative?

It is described as having laxative action in a review of the literature, [1] but I did not find a systematic review of constipation trials to read, so proper evidence was not found here. Persistent bowel changes deserve a medical check; see when to get help for digestive symptoms.

Is triphala safe?

Trials reported no serious adverse events, but they were small and short, and hypersensitivity rash occurred in one trial. [2] [3] Product contamination is a separate concern for Ayurvedic products in general. [6]

Can I take triphala with my medicines?

Memorial Sloan Kettering warns against combining it with medicines cleared by the CYP3A4 and CYP2D6 enzymes, and it may lower blood sugar, so diabetes medicines matter too. [9] [10] I did not find formal interaction studies in people to cite. Ask a pharmacist or clinician, and see talking with a health professional. Never stop a prescribed medicine on your own.

References
  1. Peterson CT, Denniston K, Chopra D. Therapeutic Uses of Triphala in Ayurvedic Medicine. J Altern Complement Med 2017;23(8):607-614. Read 2026-10-22.
  2. Phimarn W, Sungthong B, Itabe H. Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review. J Evid Based Integr Med 2021. Read 2026-10-22.
  3. Donato F, et al. Guggulu and Triphala for the Treatment of Hypercholesterolaemia: A Placebo-Controlled, Double-Blind, Randomised Trial. Complement Med Res 2021;28(3):216-225. Read 2026-10-22.
  4. AlJameel AH, Almalki SA. Effect of triphala mouthrinse on plaque and gingival inflammation: A systematic review and meta-analysis of randomized controlled trials. Int J Dent Hyg 2020;18(4):344-351. Read 2026-10-22.
  5. Intakhiao S, et al. Ameliorative Effects of Triphala Supplementation on Oxidative Stress and Inflammation in Individuals with Post-COVID-19 Condition: A Preliminary Randomized Controlled Trial. Glob Adv Integr Med Health 2025. Read 2026-10-22.
  6. Saper RB, et al. Lead, mercury, and arsenic in US- and Indian-manufactured Ayurvedic medicines sold via the Internet. JAMA 2008;300(8):915-923. Read 2026-10-22.
  7. Ayurvedic Medicine: In Depth. National Center for Complementary and Integrative Health, NIH (United States). Last updated January 2019. Read 2026-10-22.
  8. Ashwagandha: Usefulness and Safety. National Center for Complementary and Integrative Health, NIH (United States). Read 2026-10-22.
  9. Memorial Sloan Kettering Cancer Center. Triphala: Purported Benefits, Side Effects & More. Page last updated 5 January 2022. Read 2026-10-24.
  10. RxList. Terminalia. Supplement monograph, no update date shown. Read 2026-10-24.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.