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Digestive Symptoms: Red Flags and When to Get Help

Red-flag digestive symptoms and when to get help: blood in stool, black stools, severe or constant pain, persistent vomiting, dehydration, unexplained weight loss and trouble swallowing.

Content last updated . This page has not been medically reviewed.

First: emergencies

If you or someone with you has any of the following, get emergency help now. In the US, call 911. In other countries, use your local emergency number.
  • Bleeding from the bottom that will not stop, a lot of blood, or large blood clots in the stool. [1]
  • A swollen belly together with a sudden, severe stomach ache, vomiting blood or vomit that looks like ground coffee, or severe difficulty breathing. [2]
  • Chest pain that feels tight or heavy, or spreads to the arm, back, neck or jaw, with shortness of breath, which may be a heart attack even if it feels like indigestion. [3]

If you think vomiting or illness may be from poisoning, call US Poison Help at 1-800-222-1222 or see what to do first in poisoning and poison help by country. [4]

Get care promptly (the same day or next day)

Contact a clinician quickly for any of these. NIDDK says to see a doctor right away if constipation comes with several of these signs. [5]
SymptomWhy it mattersWhere it appears in this guide
Blood in the stool, or stool that is black and tarry or has red blood or pusCan signal bleeding in the digestive tract; bloody diarrhea is also a symptom of ulcerative colitis. [6][7]Diarrhea, IBD
Constant or severe belly painCan be a sign of a serious problem. [5][8]Constipation
Vomiting blood or coffee-ground vomit, persistent vomiting, or vomiting for more than 24 hoursRisk of dehydration; MedlinePlus lists this among reasons to contact a provider immediately. [4][6]Indigestion and nausea
Signs of dehydration: extreme thirst, dry mouth, urinating less, dark urine, dizzinessLoose stools and vomiting remove fluid and electrolytes. [8]Diarrhea
Unexplained weight lossListed with other warning signs for GERD, constipation, IBS and bloating. [6][5][2]Heartburn and reflux
Trouble swallowing, pain when swallowing, or food getting stuckListed as warning signs with reflux symptoms. [6][9]Heartburn and reflux
Fever with diarrhea, or inability to pass gas or stoolCan indicate infection or blockage. [8][2]Diarrhea page, bloating
Diarrhea lasting more than 2 days, six or more loose stools a day, or high fever (adults)NIDDK says to talk to a doctor right away. [8]Diarrhea page
A change in mental state (unusual irritability or lack of energy), or a child or baby who cannot drink enoughNIDDK says to talk with a doctor right away, and that a child who cannot drink enough liquids needs help right away. [8]Diarrhea page
Anemia (low red blood cells) found on a blood testListed by NIDDK as a sign that may point to a problem other than IBS. [10]IBS

Book an appointment soon

  • Symptoms that are new, keep coming back, or do not improve with self-care. [11][6]
  • A sudden change in your usual bowel habits, or needing to go more or less often than usual. [11][1]
  • Heartburn most days, or heartburn that does not respond to over-the-counter treatment. [9]
  • Indigestion that lasts more than two weeks. [12]
  • A family history of colon or rectal cancer with constipation. [5]
  • Feeling very bloated regularly or bloating that does not go away. [2]

Higher-risk groups should call earlier

Diarrhea is more likely to cause problems in people who are pregnant, over 65, taking antibiotics, or who have a weakened immune system. [13] It is especially dangerous in newborns and infants and can cause severe dehydration in a day or two. [8] Babies, children and older adults are at greater risk of dehydration. [14]

Why symptoms alone cannot say what is wrong

Digestive symptoms overlap. Rectal bleeding, bloody or black stools, anemia and weight loss are symptoms that may suggest a problem other than IBS. [10] Bowel cancer symptoms are also common to other conditions; having them does not definitely mean cancer, but it is important to get checked. [1] Doctors diagnose using your history, an exam and, when needed, blood, stool or other tests, not symptoms alone. [15][10]

What not to do

  • Do not use probiotics, cleanses or herbal products as a reason to delay a medical evaluation. [16] See the claim check on cleanses and tests.
  • Do not start a gluten-free diet before celiac testing, because it can affect results. [15]
  • Do not stop a prescribed medicine on your own. [9]

Frequently asked questions

How do I know if blood in my stool is serious?

Any blood in the stool, or black and tarry stool, should be checked by a clinician. Heavy bleeding that does not stop is an emergency. [6][1]

When is vomiting an emergency?

Vomiting blood, severe belly pain, signs of dehydration, or vomiting longer than 24 hours need prompt care. [4]

Can bloating be serious?

Usually it is not, but bloating that does not go away can occasionally be a sign of something more serious, so see a clinician if it persists. [2]

Is unintentional weight loss always a digestive problem?

No, but with digestive symptoms it is a warning sign that needs evaluation. [6]

References

  1. NHS (UK). Symptoms of bowel cancer. Read 2026-10-22.
  2. NHS (UK). Bloating. Read 2026-10-22.
  3. NHS (UK). Feeling sick (nausea). Read 2026-10-22.
  4. MedlinePlus (U.S. National Library of Medicine). Nausea and Vomiting. Read 2026-10-22.
  5. National Institute of Diabetes and Digestive and Kidney Diseases (NIH). Symptoms & Causes of Constipation. Read 2026-10-22.
  6. National Institute of Diabetes and Digestive and Kidney Diseases (NIH). Symptoms & Causes of GER & GERD. Read 2026-10-22.
  7. National Institute of Diabetes and Digestive and Kidney Diseases (NIH). Symptoms & Causes of Ulcerative Colitis. Read 2026-10-22.
  8. National Institute of Diabetes and Digestive and Kidney Diseases (NIH). Symptoms & Causes of Diarrhea. Read 2026-10-22.
  9. NHS (UK). Heartburn and acid reflux. Read 2026-10-22.
  10. National Institute of Diabetes and Digestive and Kidney Diseases (NIH). Diagnosis of Irritable Bowel Syndrome. Read 2026-10-22.
  11. NHS (UK). Constipation. Read 2026-10-22.
  12. MedlinePlus (U.S. National Library of Medicine). Indigestion. Read 2026-10-22.
  13. National Institute of Diabetes and Digestive and Kidney Diseases (NIH). Definition & Facts for Diarrhea. Read 2026-10-22.
  14. NHS (UK). Dehydration. Read 2026-10-22.
  15. National Institute of Diabetes and Digestive and Kidney Diseases (NIH). Diagnosis of Celiac Disease. Read 2026-10-22.
  16. National Center for Complementary and Integrative Health (NIH). Probiotics: Usefulness and Safety. Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.