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Unintentional Weight Loss: Why It Matters

Losing weight without trying can have many causes, from stress to medical conditions. Learn the common reasons, what a clinician may ask, and why to get it checked.

Content last updated . This page has not been medically reviewed.

Safety first

Losing weight when you are not trying to lose weight is a reason to see a doctor. NHS says unintentional weight loss can be a sign of stress or a serious illness and advises seeing a GP just in case; it says that if you keep losing weight without changing your diet or exercise routine, you should see a GP, and as soon as possible if you also have other symptoms, because the earlier the cause is found, the sooner it can be treated. [1] If you think the loss could be related to an eating disorder, see Eating disorders and disordered eating for urgent help options.

What counts as significant

MedlinePlus defines unintentional weight loss as a loss of 10 pounds (4.5 kg) or 5% of your normal body weight over 6 to 12 months or less without knowing the reason, and advises contacting a provider in that situation or if you have other symptoms. [2] Weight loss that is intended, for example through a program or medicine, is covered on other pages such as Healthy weight basics.

Common causes

The sources list many possible causes. This does not mean any of them applies to you.
AreaExamples from the sources
Stress and mental healthStressful events such as divorce, job loss or bereavement; depression, anxiety, eating disorders and obsessive compulsive disorder. [1]
DigestionCeliac disease, inflammatory bowel disease; long-lasting infections; overuse of laxatives; removal of part of the small intestine. [1][2]
Hormones and metabolismOveractive thyroid; type 1 diabetes; undiagnosed diabetes. [1][2]
Heart and other chronic illnessHeart failure; chronic illnesses such as COPD or Parkinson disease. [1][2]
Nutrition and appetitePoor nutrition or lack of appetite, though weight can fall even when diet and appetite have not changed. [1]
MedicinesSide effects of some medicines such as levothyroxine; MedlinePlus also lists chemotherapy and thyroid medicines. [1][2]
SubstancesMedlinePlus lists drug use such as amphetamines and cocaine. [2]
CancerSometimes weight loss and loss of appetite can be caused by cancer, which is why it is important to get it checked. [1]

NIDDK also notes that people with type 1 diabetes may have unexplained weight loss along with increased urination and thirst. [3] See Celiac disease and gluten-related symptoms, Thyroid problems and fatigue and Appetite changes and unintended weight loss in older adults.

What to expect at a visit

NHS says a GP will ask about your health and may arrange tests or scans, then advise on ways to help, treat any condition causing it, or refer you to a specialist. [1] MedlinePlus says a provider will do a physical exam, check your weight and ask about things such as how much weight you lost, how fast, eating and exercise changes, stress, vomiting, medicines and mood. [2] Bring a list of your medicines and supplements.

What to avoid

  • Getting the cause checked comes first. The sources advise a visit to a clinician, not self-treatment with supplements, weight-gain products or restrictive diets. [1][2]
  • Ignoring it because the change feels welcome. NHS advises getting it checked when you are losing weight without trying. [1]

When to get help

See a clinician if you have lost weight without trying, especially if you have other symptoms, are losing weight over months, or are unsure why. [1][2]

Frequently asked questions

How much weight loss is too much?

MedlinePlus uses 10 pounds (4.5 kg) or 5% of normal body weight over 6 to 12 months or less, without a known reason, as a point to contact a provider, and also advises contacting one if you have other symptoms along with the weight loss. [2]

Can stress cause weight loss?

Yes, NHS lists stressful events and mental health conditions among causes. [1] It is still sensible to have it checked.

Is unexplained weight loss always serious?

No, but NHS says it can be a sign of serious illness, so a check is advised. [1]

References

  1. NHS. Unintentional weight loss. Read 2026-10-22.
  2. MedlinePlus. Weight loss - unintentional. Read 2026-10-22.
  3. NIDDK. Symptoms and causes of diabetes. Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.