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Each record is a registered study, a systematic-review registration or a publication. A registered or ongoing study is not a finding, and animal or cell research does not show an effect in people. The same study can appear under more than one subject, so the number of records is not a count of independent studies. You can also search an exact DOI, PubMed ID, NCT or CRD number. How to read these records.
56 study records (showing up to 30 per record type)
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Registered trial NCT06060340 Early_Phase 1 Not completed: RecruitingClinical and Radiographic Outcomes of Class II Furcation Defects Management Using Propolis: A Case SeriesCondition or outcome area: Furcation Defects
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Registered trial NCT06148740 Not completed: RecruitingAn Investigation of the Effects of a Skin Serum Containing Propolis on Skin Health and AppearanceCondition or outcome area: Skin Health
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Registered trial NCT06029023 Phase 1 Not completed: RecruitingClinical And Radiographic Evaluation Of Nano-Propolis, Nano-Curcumin and MTA as Direct Pulp Capping Agents in Young Permanant TeethCondition or outcome area: Traumatic Pulp Exposure in Children
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Registered trial NCT05870059 Phase 2 Completed (results not assessed here)Comparative Evaluation of Propolis Mouthwash With 0.2% Chlorhexidine Mouthwash in Improving the PeriodontitisCondition or outcome area: Periodontal Diseases
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Registered trial NCT05793099 Completed (results not assessed here)Effect of 5% Aqueous Propolis in Salivary and Dental Plaque pH in ChildrenCondition or outcome area: Child|Saliva|Dental Plaque
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Registered trial NCT05770297 Not completed: RecruitingEffect of Propolis Administration for Dysmenorrhea in Endometriosis Patient With Levonorgestrel Implant TherapyCondition or outcome area: Endometriosis|Dysmenorrhea
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Registered trial NCT05717881 Completed (results not assessed here)Impact of Poplar Propolis on Metabolic Disturbances of Insulin ResistanceCondition or outcome area: Insulin Resistance
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Registered trial NCT05974748 Phase 3 Completed (results not assessed here)Role of Propolis Endodontic Irrigant on Post-Operative PainCondition or outcome area: Post-operative Pain|Symptomatic Irreversible Pulpitis
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Registered trial NCT00231218 Phase 3 Completed (results not assessed here)Echinacea, Propolis and Vitamin C for URI Prevention in PreschoolersCondition or outcome area: Common Cold|Gastroenteritis2006-01 · Subject: L-Ascorbic Acid; Ascorbic acid; l-ascorbic acid · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT00231218 Phase 3 Completed (results not assessed here)Echinacea, Propolis and Vitamin C for URI Prevention in PreschoolersCondition or outcome area: Common Cold|Gastroenteritis2006-01 · Subject: Song Guo Ju; 松果菊; Echinacea; Echinacea Purpurea · open the herb record · ClinicalTrials.gov
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Registered trial NCT04942470 Completed (results not assessed here)Effect of Aloe Vera and Propolis on Wound Healing in Pressure InjuriesCondition or outcome area: Pressure Ulcer
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Registered trial NCT04382079 Not completed: UnknownHoney Products for Cancer Patients With Oral Mucositis: a Randomized Controlled TrialCondition or outcome area: Oral Mucositis
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Registered trial NCT04789083 Completed (results not assessed here)The Effect of Propolis in Tinea Pedis Treatment: A Randomized Controlled StudyCondition or outcome area: Nurse's Role|Patient Education|Foot Care
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Registered trial NCT03416127 Phase 2 Completed (results not assessed here)Effect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes MellitusCondition or outcome area: Diabetes Mellitus, Type 2
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Registered trial NCT04983524 Completed (results not assessed here)Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic PulpCondition or outcome area: Post-Operative Pain, Chronic|Necrotic Pulp
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Registered trial NCT04374006 Early_Phase 1 Completed (results not assessed here)Effects of Sulawesi Propolis Extract on Lesion Growth, Apoptotic and Inflammatory Activity of the Rat Endometriosis TissueCondition or outcome area: Endometriosis; Peritoneum|Endometriosis
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Registered trial NCT02818803 Phase 3 Completed (results not assessed here)Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal AntisepticCondition or outcome area: Candidiasis, Oral|Stomatitis, Denture
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Registered trial NCT04754763 Early_Phase 1 Completed (results not assessed here)A Comparative Study On The Effect Of Propolis And Dentine Bonding Agent In Treating Dentine HypersensitivityCondition or outcome area: Dentine Hypersensitivity
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Registered trial NCT04819867 Phase 2 / Phase 3 Completed (results not assessed here)Comparison Of The Effect Of Propolis And Gluma Desensitizer On The Management Of Dentin HypersensitivityCondition or outcome area: Dentin Hypersensitivity
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Registered trial NCT04916821 Not completed: UnknownInvestigation of Clinical Effectiveness of Propolis Extracts as Food Supplements in Patients With SARS-CoV-2(COVID-19)Condition or outcome area: SARS-CoV2 Infection
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Registered trial NCT02794506 Phase 4 Completed (results not assessed here)Propolis Improves Glycemic Control in Subjects With Type 2 Diabetes and Chronic PeriodontitisCondition or outcome area: Diabetes Mellitus|Periodontitis
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Registered trial NCT03723980 Phase 3 Completed (results not assessed here)Role of Propolis Paste in Preventing Pain After Root Canal Treatment.Condition or outcome area: Pain, Postoperative
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Registered trial NCT04117451 Completed (results not assessed here)The Effect of Propolis Mouthwash Compared to Chlorhexidine Mouthwash on Oral and Cardiovascular HealthCondition or outcome area: Blood Pressure|Periodontal Diseases
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Registered trial NCT05250661 Completed (results not assessed here)Efficacy of Propolis in the Prevention of Oral MucositisCondition or outcome area: Oral Mucositis
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Registered trial NCT02766036 Phase 2 Completed (results not assessed here)Propolis Effects in Patients With Chronic Kidney DiseaseCondition or outcome area: Chronic Kidney Diseases
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Registered trial NCT03649243 Completed (results not assessed here)Propolis as Adjuvant in the Healing of Human Diabetic Foot WoundsCondition or outcome area: Diabetes Mellitus, Type 2
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Registered trial NCT05083052 Completed (results not assessed here)Propolis in Reducing Dentin HypersensitivityCondition or outcome area: Dentin Sensitivity
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Registered trial NCT04411758 Completed (results not assessed here)Propolis for Patients With Chronic Kidney Disease.Condition or outcome area: Chronic Kidney Diseases|Inflammation
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Registered trial NCT01453582 Phase 3 Completed (results not assessed here)Efficacy and Safety Study of Total Flavonoids of Propolis Dropping Pill to Treat Angina PectorisCondition or outcome area: Stable Angina Pectoris
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Registered trial NCT01375088 Phase 2 Completed (results not assessed here)Assessing the Preventing and Therapeutic Effect of Propolis in Radiotherapy Induced Mucositis of Head and Neck CancersCondition or outcome area: Radiation-induced Mucositis of Oral Mucous Membranes
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Systematic review registration CRD42023494412 Registered protocol, no results here: Review Completed not publishedCan Propolis be A Useful Therapy for Chronic Kidney Disease? A Systematic Review of Novel EvidencesCondition or outcome area: Propolis in reducing the severity of chronic kidney disease patients.
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Systematic review registration CRD42023474033 Registered protocol, no results here: Review OngoingThe effects of propolis on oxidative stress and inflammation: A systematic review and meta-analysisCondition or outcome area: oxidative stress and inflammation
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Systematic review registration CRD42023472448 Registered protocol, no results here: Review OngoingThe effects of Propolis on blood pressure, lipid profile, and glycemic indices in adults: A systematic review and Meta-analysisCondition or outcome area: blood pressure, lipid profile, and glycemic indices
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Systematic review registration CRD42023472447 Registered protocol, no results here: Review OngoingThe effect of Propolis on liver enzymes and obesity indices: A systematic review and Meta-analysisCondition or outcome area: liver enzymes and obesity indices
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Systematic review registration CRD42023470555 Registered protocol, no results here: Review OngoingCan propolis supplementation reduce serum concentration of inflammatory mediators? An updated systematic review and dose-response meta-analysis on randomized clinical trialsCondition or outcome area: Inflammatory diseases such as the metabolic syndrome, fatty liver, hypertension, cardiovascular diseases, and diabetes mellitus have high risk of mortality and morbidity, severe consequences, and high social costs worldwide. New evidence revealed the beneficial effects of some nutrients with antioxidant and anti-inflammatory features on the management and prevention of these diseases. Therefore, the utilization of these functional foods with antioxidants or anti-inflammatory properties is increa
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Systematic review registration CRD42023467573 Registered protocol, no results here: Review OngoingPropolis natural remedy in reducing dental plaque and gingival inflammation: asystematic review and meta-analysisCondition or outcome area: The clinical efficacy of propolis mouthwashes.
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Systematic review registration CRD42023466736 Registered protocol, no results here: Review OngoingIn vitro evaluation of propolis extracts against cariogenic microorganisms: A systematic reviewCondition or outcome area: Dental caries microrganisms. Antimicrobial natural compound. Minimal side effect.
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Systematic review registration CRD42023456031 Registered protocol, no results here: Review OngoingMost effective propolis extract in type 2 diabetes treatment: a systematic review and meta-analysis of clinical trialsCondition or outcome area: Type 2 diabetes mellitus affects approximately 537 million people globally, making it one of the leading causes of morbidity and mortality today, posing a significant challenge for global public health. While conventional treatment involves diet, physical exercise, and oral or injectable medications, it's common for many individuals to seek alternative approaches, such as natural products, in an attempt to control their blood glucose levels. Previous studies have linked propolis extracts to the
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Systematic review registration CRD42023455345 Registered protocol, no results here: Review OngoingEffect of Propolis on Dental Pulp Stem Cells- A Systematic ReviewCondition or outcome area: All in-vitro and in-vivo studies including Effects of Propolis on Human Dental Pulp Stem Cells will be studied.
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Systematic review registration CRD42023445364 Registered protocol, no results here: Review OngoingPropolis efficiency against Enterococcus faecalis compared with other intracanal medicaments: a systematic review with meta-analysisCondition or outcome area: Propolis efficiency as intracanal medicament against Enterococcus faecalis
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Systematic review registration CRD42023434308 Registered protocol, no results here: Review OngoingThe Effectiveness Oral Propolis On Mucosa Wound Healing After Removal Third Molars Surgery: A Systematic ReviewCondition or outcome area: The third molars are the most commonly impacted teeth, and extraction is one of the most common procedures. The complication after the third molar extraction requires conventional medical treatment, such as propolis. Propolis and its components have anti-inflammatory, immunomodulatory, and antitumor activities. Propolis is proven to be an herbal product used in post-operative wound healing, reducing inflammation and accelerating granulation tissue healing and epithelialization.
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Systematic review registration CRD42023433636 Registered protocol, no results here: Review OngoingEffects of 21 Dietary nutrientsInterventions on Type 2 diabetes:a network meta-analysisCondition or outcome area: It is estimated that there will be more than 500 million T2DM patients in the world by 2030, followed by an increase in diabetes related complications and the corresponding increase in medical expenditure. In order to curb the prevalence of T2DM, it is urgent to find effective measures to prevent and treat T2DM
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Systematic review registration CRD42023413891 Registered protocol, no results here: Review OngoingAntioxidant Effectiveness of Propolis: A Systematic Review and Meta-AnalysisCondition or outcome area: Adult humans of both sexes as subjects, with pathological conditions related to oxidative stress
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Systematic review registration CRD42020201052 Registered protocol, no results here: Review OngoingComparison of antibacterial activity of propolis and chlorhexidine as an intra canal medicament against enterococcus faecalis - a systematic review and meta analysisCondition or outcome area: Propolis is natural medicament and is free from the side effects associated with chlorhexidine medicament. Studies reported superiority of one over other, therefore the objective of this systematic review is to assess the antibacterial activity of propolis in comparison to chlorhexidine as an intra canal medicament against enterococcus faecalis.2020-08-26 · Subject: 4-hexyl alcohol acetate; Chlorhexidine; chlorhexidine; 55-56-1; Rotersept; Fimeil; Hexadol; Soretol; Chlorhexidin; Chlorhexidinum · open the ingredient record
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Systematic review registration CRD42020183193 Registered protocol, no results here: Review OngoingEffectiveness of Cocoa on Dental Caries: A Systematic ReviewCondition or outcome area: Dental caries are the most worldwide prevalent oral infectious disease. The prime biological factor being the attached virulent biofilms to the teeth surface. The most common approach till date used for prevention of dental caries is Flouride. But in place of all these known approaches which can have side effects also, recently various natural products are being brought into use such as propolis, green tea extracts, cranberry, essential oils from various plants, Garlic, Neem, Shells of crustance
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Systematic review registration CRD42019126555 Registered protocol, no results here: Review OngoingGlycemic control effect of royal jelly and propolis in type 2 diabetic patients; a systematic review and meta analysis of randomized control trialsCondition or outcome area: Diabetes mellitus (DM) is a disease characterized by high blood glucose and resulting in defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels. The impacts of type 2 diabetes mellitus (T2DM) on global health care and economy are enormous. Glucose control remains a major focus in the management of patients with typ
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Publication PMID 34203569 Research model: Animal ExperimentEffects of Baccharin Isolated from Brazilian Green Propolis on Adipocyte Differentiation and Hyperglycemia in ob/ob Diabetic MiceCondition or outcome area: diabetic; glucose metabolic disorders; type 2 diabetes mellitusInt J Mol Sci · 2021 · Subject: Baccharin; CID 45114377; 61251-97-6; (22E)-16-hydroxy-19-(1-hydroxyethyl)-6,15,27-trimethylspiro[2,5,11,14,18,25-hexaoxahexacyclo[24.2.1.03,9.04,6.09,27.013,15]nonacosa-20,22-diene-28,2'-oxirane]-12,24-dione; (2E)-3-(3-(3-Methyl-2-buten-1-yl)-4-((3-phenylpropanoyl)oxy)phenyl)acrylic acid; (1R,3S,4S,13S,15R,16S,19R,20E,22Z,26R,27S,28S)-16-hydroxy-19-[(1R)-1-hydroxyethyl]-6,15,27-trimethylspiro[2,5,11,14,18,25-hexaoxahexacyclo[24.2.1.03,9.04,6.09,27.013,15]nonacosa-20,22-diene-28,2'-oxirane]-12,24 · open the ingredient record · DOI 10.3390/ijms22136954
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Publication PMID 34638666 Research model: Cell ExperimentProtective Effects of Ethanol Extract of Brazilian Green Propolis and Apigenin against Weak Ultraviolet Ray-B-Induced Barrier Dysfunction via Suppressing Nitric Oxide Production and Mislocalization of Claudin-1 in HaCaT CellsCondition or outcome area: barrier dysfunctionInt J Mol Sci · 2021 · Subject: Apigenin; 520-36-5; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; Versulin; Apigenol; Chamomile; 4',5,7-Trihydroxyflavone; Spigenin; Apigenine; C.I. Natural Yellow 1 · open the ingredient record · DOI 10.3390/ijms221910326
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Publication PMID 35624893 Research model: Animal ExperimentAnti-Inflammatory, Anti-Apoptotic, and Antioxidant Roles of Honey, Royal Jelly, and Propolis in Suppressing Nephrotoxicity Induced by Doxorubicin in Male Albino RatsCondition or outcome area: nephrotoxicityAntioxidants (Basel) · 2022 · Subject: Feng Ru; 蜂乳; Royal Jelly; Lac Regis Apis · open the herb record · DOI 10.3390/antiox11051029
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Publication PMID 34948335 Research model: Cell ExperimentEvaluation of the Skin-Sensitizing Potential of Brazilian Green PropolisInt J Mol Sci · 2021 · Subject: Feng Jiao; 蜂胶; Propolis · open the herb record · DOI 10.3390/ijms222413538
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Publication PMID 34862831 Research model: Cell ExperimentBrazilian green propolis: A novel tool to improve the cytotoxic and immunomodulatory action of docetaxel on MCF-7 breast cancer cells and on women monocyteCondition or outcome area: tumor; breast cancerPhytother Res · 2022 · Subject: Feng Jiao; 蜂胶; Propolis · open the herb record · DOI 10.1002/ptr.7345
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Publication PMID 34360606 Research model: Cell ExperimentMetabolomic Identification of Anticancer Metabolites of Australian Propolis and Proteomic Elucidation of Its Synergistic Mechanisms with Doxorubicin in the MCF7 CellsCondition or outcome area: breast adenocarcinoma; breast cancerInt J Mol Sci · 2021 · Subject: Feng Jiao; 蜂胶; Propolis · open the herb record · DOI 10.3390/ijms22157840
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Publication PMID 33322005 Research model: Cell ExperimentPropolis Suppresses UV-Induced Photoaging in Human Skin through Directly Targeting Phosphoinositide 3-Kinase
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Publication PMID 33279402 Research model: Animal ExperimentPropolis suppresses cytokine production in activated basophils and basophil-mediated skin and intestinal allergic inflammation in miceCondition or outcome area: basophil-dependent allergic inflammation; ovalbumin-induced intestinal anaphylaxisAllergol Int · 2021 · Subject: Feng Jiao; 蜂胶; Propolis · open the herb record · DOI 10.1016/j.alit.2020.11.005
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Publication PMID 32660099 Research model: Cell ExperimentCuban Brown Propolis Interferes in the Crosstalk between Colorectal Cancer Cells and M2 MacrophagesCondition or outcome area: cancer; colorectal cancer
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Publication PMID 32184916 Research model: Animal ExperimentChemopreventive Effects of Propolis in the MNU-Induced Rat Mammary Tumor ModelCondition or outcome area: grade I tumors; tumor; cancer; mammary tumors; tumorsOxid Med Cell Longev · 2020 · Subject: Feng Jiao; 蜂胶; Propolis · open the herb record · DOI 10.1155/2020/4014838