modern wellness · Symptom

Osteoarthritis

🩺 HPO Source

HPO ID

HPO Label

Osteoarthritis

HPO Definition

Degeneration (wear and tear) of articular cartilage, i.e., of the joint surface. Joint degeneration may be accompanied by osteophytes (bone overgrowth), narrowing of the joint space, regions of sclerosis at the joint surface, or joint deformity.

🔤 Synonyms (1)

Synonyms

Degenerative joint disease

🔗 Cross-References (3)

SNOMEDCT_US225655006

SNOMEDCT_US396275006

UMLSC0029408

🔼 Broader Terms (1)

HP:0001369Arthritis

🏥 Conditions where Osteoarthritis appears

31 · bridged via HPO ↔ OMIM

syndrome OMIM 118600

Calcium Pyrophosphate Arthropathy

freq: 11/11 ev: PCS

syndrome OMIM 184300

Cervical Spondylosis

syndrome OMIM 251450

Desbuquois Dysplasia 1

syndrome OMIM 251450

Desbuquois Syndrome

syndrome OMIM 130000

Ehlers-Danlos Syndrome, Classic Type, 1

syndrome OMIM 618000

Ehlers-Danlos Syndrome, Classic-Like, 2

freq: 2/2 ev: PCS

syndrome OMIM 130020

Ehlers-Danlos Syndrome, Type 3 (Disorder)

syndrome OMIM 600969

Epiphyseal Dysplasia, Multiple, 3

syndrome OMIM 600969

Epiphyseal Dysplasia, Multiple, 3, With Myopathy

syndrome OMIM 614135

Epiphyseal Dysplasia, Multiple, 6

freq: 2/2 onset: HP:0003621 ev: PCS

phenotype OMIM 140600

syndrome OMIM 606069

Hemochromatosis, Type 4

freq: 2/20 ev: PCS

syndrome OMIM 306700

syndrome OMIM 306900

syndrome OMIM 277900

Hepatolenticular Degeneration

syndrome OMIM 608654

Hereditary Sensory Autonomic Neuropathy, Type 5

freq: 1/3 ev: PCS

syndrome OMIM 142669

Hip Dysplasia, Beukes Type

syndrome OMIM 307800

Hypophosphatemic Rickets, X-Linked Dominant

syndrome OMIM 613795

Loeys-Dietz Syndrome 3

freq: 33/63 ev: PCS

syndrome OMIM 602111

Metaphyseal Anadysplasia 1

syndrome OMIM 140600

Osteoarthritis of Distal Interphalangeal Joint

syndrome OMIM 140600

Osteoarthritis of The Hand

phenotype OMIM 140600

Osteoarthritis Susceptibility 2

syndrome OMIM 616833

Paget Disease of Bone 6

disease OMIM 208230

Progressive Pseudorheumatoid Dysplasia

disease OMIM 177170

Pseudoachondroplasia

freq: 11/16 ev: PCS

syndrome OMIM 615582

Rienhoff Syndrome

freq: 2/43 ev: PCS

syndrome OMIM 602111

Spondyloepimetaphyseal Dysplasia, Missouri Type

syndrome OMIM 108300

Stickler Syndrome, Type 1

freq: 18/22 ev: PCS

syndrome OMIM 190350

Trichorhinophalangeal Dysplasia Type I

onset: HP:0003584 ev: TAS

syndrome OMIM 307800

Vitamin D-Resistant Rickets, X-Linked

📜 Formulas studied for Osteoarthritis

8 · text-bridged via indications + syndromes

Gucining Capsule; Gu Ci Ning Capsule

Gucining Jiaonang

Used for osteoarthritis caused by blood stasis and collaterals, symptoms such as joint pain, swelling, numbness, and limited mobility

Gu You Ling Liniment; Guyouling Liniment

Guyouling Chaji

Used for osteoarthritis and soft tissue damage caused by blood stasis and obstruction of the collaterals, symptoms such as joint swelling, pain, and limited mobility

Kang Gu Zeng Sheng Capsule; Kanggu Zengsheng Capsule

Kanggu Zengsheng Jiaonang

For osteoarthritis, liver and kidney deficiency, blood stasis and collateral obstruction syndrome, symptoms such as joint swelling, numbness, pain, and limited mobility

Kang Gu Zeng Sheng Pill; Kanggu Zengsheng Pill

Kanggu Zengsheng Wan

For osteoarthritis, liver and kidney deficiency, blood stasis and collateral obstruction syndrome, symptoms such as joint swelling, numbness, pain, and limited mobility

Qian Shan Huo Xue Plaster

Qian Shan Huo Xue Gao

Joint swelling, pain, impaired mobility, traumatic injury, waist and knee osteoarthritis see the above symptoms

Tongluo Qutong Plaster; Tong Luo Qu Tong Plaster

Tongluo Qutong Gao

Used for waist and knee osteoarthritis, stagnation of blood, cold and dampness syndrome, symptoms of joint tingling or dull pain, joint stiffness, poor flexion and extension, chills, cold limbs, cervi

Zhuang Gu Guan Jie Pill; Zhuanggu Guanjie Pill

Zhuanggu Guanjie Wan

It is used for osteoarthritis and lumbar muscle strain caused by liver and kidney deficiency, blood stasis and qi stagnation, and arthral obstruction. Symptoms of joint swelling, pain, numbness, and l

Wu Wei Gan Lu Yao Yu Xi Ji

Wu Wei Gan Lu Yao Yu Xi Ji

Rheumatoid heat evil, arthralgia, swelling, heat pain, and unfavorable flexion and extension caused by blockage of the meridian; rheumatoid arthritis, rheumatoid arthritis, and osteoarthritis see the

🔗 Knowledge Graph Connections

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Real research connections from HERB 2.0, TCMSP, and clinical evidence sources. 18 related entities shown — click any to follow the trail.

🧬 Gene targets implicated · 5

72 kDa type IV collagenase

Interstitial collagenase

Prostaglandin G/H synthase 2

🧪 Compounds reaching those targets · 12

(+)-leucocyanidin

Beta-sitosterol

Leucopelargonidin

🌿 Herbs studied for this · 1