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Bacopa (Brahmi) in Ayurveda

Bacopa monnieri (brahmi) in Ayurveda: its place among the medhya rasayana herbs, what trials found for memory and attention, the name confusion with gotu kola, and safety limits.

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What it is and how Ayurveda describes it

Bacopa monnieri is a plant that Ayurveda calls brahmi. A 2025 review reports that the Charaka Samhita presents bacopa as a plant for treating various mental disorders and calls it a "medhya rasayana". [4] Medhya rasayana is a class of herbs the tradition describes as rejuvenating and as supporting memory, mental health and intellect. [5] This is the tradition's description, not a trial result.

A name that points to two plants. "Brahmi" in Ayurvedic practice corresponds to two different plants, Bacopa monnieri and Centella asiatica. [6] The second plant is called mandukaparni in Ayurvedic texts and trials [7] and gotu kola in English. [8] A bottle labeled "brahmi" may therefore contain either one, and they have different evidence and safety profiles. See gotu kola (mandukaparni). Check the Latin name on a label.

What research has measured

The meta-analysis of 2014 included only trials of standardized extracts taken for 12 weeks or more, not traditional preparations. [9]
5 findings · 3 supported · 2 limited or unclearThe colour follows the evidence label on each card.
  1. Overall cognition in adults

    Promising but limited

    A 2014 meta-analysis of 9 randomized trials (518 people) [10] found a possible improvement in cognition, particularly speed of attention. [11] The authors said only a large, well-designed head-to-head trial against an existing medication would give definitive data. [12]

  2. Memory

    Promising but limited

    A 2012 systematic review of 6 trials, all 12 weeks long, found improved performance on 9 of 17 tests of memory free recall. [13] [14] It found little evidence of benefit in other thinking skills. [15]

  3. Healthy adults, compared with ginkgo

    Promising but limited

    A 2026 network meta-analysis of 29 trials (2,107 people) [16] said bacopa shows promise as a cognitive enhancer, but found no significant differences in sustained attention, selective attention or processing speed, and noted the lack of direct comparisons. [17] [18] [19]

  4. Children and teens

    Insufficient evidence

    A 2016 review of 5 studies reported benefits for some memory and attention measures, mild side effects in 2.3% of participants, and called for replicated, rigorous studies. [20] [21] [22]

  5. Dementia or mild cognitive impairment

    Insufficient evidence

    The reviewers said a trial in healthy or dementia patients using a standardized preparation is still needed. [12]

The reviews show benefit on some tests and not others, which is why the label is "promising but limited" and not "established". Results came from specific extracts, so they may not apply to other products.

A trial that compared two herbs with each other. A 2025 trial in India randomized 180 healthy boys aged 8 to 10 to brahmi (Bacopa) or mandukaparni (Centella). [23] [24] It had no placebo group, so it cannot show that either herb works, and its subgroup results by prakriti (a traditional constitution type) cannot show that prakriti matters. [25] Single trials like this cannot settle the question, so this page relies mainly on systematic reviews.

Where this fits

For the supplement view see botanical and mushroom nootropics and nootropic evidence by outcome. For the Ayurvedic context see Ayurveda for memory and brain health.

Frequently asked questions

Is brahmi the same as bacopa?

Sometimes. "Brahmi" is used for two plants, Bacopa monnieri and Centella asiatica (gotu kola), so check the Latin name. [6]

Does bacopa improve memory?

Reviews found improved performance on some memory tests, particularly free recall, and little evidence for other thinking skills. The label is promising but limited. [14] [15]

How long do trials of bacopa last?

The trials in the 2012 review all lasted 12 weeks. [13]

What are the side effects?

Stomach and bowel upset is the most commonly reported problem, and no serious adverse effects were reported in one 2025 review. [1]

Is bacopa safe in pregnancy or for children?

Research on pregnancy and breastfeeding is lacking, and the child evidence is limited, so use only with a clinician's guidance. [3] [22]

More details: evidence, limits and cautions

The details behind this page: cautions, limits of the evidence and where sources disagree. Open any note to read it.

Safety first
Bacopa is generally reported as well tolerated, but that does not mean it suits everyone. A 2025 review found no reports of serious adverse effects, with stomach and bowel upset the most common problem. [1] It also says interactions with some medicines and conditions such as an overactive thyroid should be considered, and that research on safe use in pregnancy and breastfeeding is lacking. [2] [3] We searched PubMed for bacopa-specific liver injury reports and did not find any, which is not proof of safety. Ask a doctor or pharmacist before using it, especially with medicines. Memory loss that is new or getting worse needs a medical check, not only a supplement. See memory changes: when to get help.
Safety details
  • Stomach and bowel. Nausea, cramps and frequent bowel movements appeared after prolonged use in one older-adult study described in the 2025 review. [26]
  • Medicines and thyroid. The review advises considering interactions and conditions like hyperthyroidism. [2] Talk with a pharmacist, and see how interactions work.
  • Pregnancy and breastfeeding. Research on safe use is lacking. [3] Avoid unless a clinician advises otherwise.
  • Children. Use only under a clinician's guidance; the pediatric evidence is limited. [22]
  • Quality. In the US, supplements are not approved by the FDA before sale, [27] and the FDA warns that metals in some Ayurvedic products make them potentially harmful. [28] See how supplements are regulated.
References
  1. Gościniak A et al. Bacopa monnieri: preclinical and clinical evidence of neuroactive effects, safety of use and the search for improved bioavailability. Nutrients 2025 (review, PMC12158153). Read 2026-10-22.
  2. Gościniak A et al. Bacopa monnieri: preclinical and clinical evidence of neuroactive effects, safety of use and the search for improved bioavailability. Nutrients 2025 (review, PMC12158153). Read 2026-10-22.
  3. Gościniak A et al. Bacopa monnieri: preclinical and clinical evidence of neuroactive effects, safety of use and the search for improved bioavailability. Nutrients 2025 (review, PMC12158153). Read 2026-10-22.
  4. Gościniak A et al. Bacopa monnieri: preclinical and clinical evidence of neuroactive effects, safety of use and the search for improved bioavailability. Nutrients 2025 (review, PMC12158153). Read 2026-10-22.
  5. Gościniak A et al. Bacopa monnieri: preclinical and clinical evidence of neuroactive effects, safety of use and the search for improved bioavailability. Nutrients 2025 (review, PMC12158153). Read 2026-10-22.
  6. Shinomol GK et al. Exploring the role of “Brahmi” (Bacopa monnieri and Centella asiatica) in brain function and therapy. Recent Pat Endocr Metab Immune Drug Discov 2011. Read 2026-10-22.
  7. Verma J et al. Comparative efficacy of Medhya Rasayana, Bacopa monnieri and Centella asiatica in enhancing memory and IQ of 8-10 year-old healthy boys: a prakriti-based randomized controlled trial. J Ayurveda Integr Med 2025 (PMC12270740). Read 2026-10-22.
  8. Therapeutic potential of gotu kola, phosphatidylcholine and taurine in mood disorders: a systematic scoping review. Complement Med Res 2026. Read 2026-10-22.
  9. Kongkeaw C et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014. Read 2026-10-22.
  10. Kongkeaw C et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014. Read 2026-10-22.
  11. Kongkeaw C et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014. Read 2026-10-22.
  12. Kongkeaw C et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014. Read 2026-10-22.
  13. Pase MP et al. The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials. J Altern Complement Med 2012. Read 2026-10-22.
  14. Pase MP et al. The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials. J Altern Complement Med 2012. Read 2026-10-22.
  15. Pase MP et al. The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials. J Altern Complement Med 2012. Read 2026-10-22.
  16. Network meta-analysis of Bacopa monnieri and Ginkgo biloba on cognitive functions in healthy adults. Phytomedicine 2026. Read 2026-10-22.
  17. Network meta-analysis of Bacopa monnieri and Ginkgo biloba on cognitive functions in healthy adults. Phytomedicine 2026. Read 2026-10-22.
  18. Network meta-analysis of Bacopa monnieri and Ginkgo biloba on cognitive functions in healthy adults. Phytomedicine 2026. Read 2026-10-22.
  19. Network meta-analysis of Bacopa monnieri and Ginkgo biloba on cognitive functions in healthy adults. Phytomedicine 2026. Read 2026-10-22.
  20. Kean JD et al. A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations. Complement Ther Med 2016. Read 2026-10-22.
  21. Kean JD et al. A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations. Complement Ther Med 2016. Read 2026-10-22.
  22. Kean JD et al. A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations. Complement Ther Med 2016. Read 2026-10-22.
  23. Verma J et al. Comparative efficacy of Medhya Rasayana, Bacopa monnieri and Centella asiatica in enhancing memory and IQ of 8-10 year-old healthy boys: a prakriti-based randomized controlled trial. J Ayurveda Integr Med 2025 (PMC12270740). Read 2026-10-22.
  24. Verma J et al. Comparative efficacy of Medhya Rasayana, Bacopa monnieri and Centella asiatica in enhancing memory and IQ of 8-10 year-old healthy boys: a prakriti-based randomized controlled trial. J Ayurveda Integr Med 2025 (PMC12270740). Read 2026-10-22.
  25. Verma J et al. Comparative efficacy of Medhya Rasayana, Bacopa monnieri and Centella asiatica in enhancing memory and IQ of 8-10 year-old healthy boys: a prakriti-based randomized controlled trial. J Ayurveda Integr Med 2025 (PMC12270740). Read 2026-10-22.
  26. Gościniak A et al. Bacopa monnieri: preclinical and clinical evidence of neuroactive effects, safety of use and the search for improved bioavailability. Nutrients 2025 (review, PMC12158153). Read 2026-10-22.
  27. NCCIH, Ashwagandha: Usefulness and Safety (last updated March 2023), regulation. Read 2026-10-22.
  28. NCCIH, Ayurvedic Medicine: In Depth (last updated January 2019), safety. Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.