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Each record is a registered study, a systematic-review registration or a publication. A registered or ongoing study is not a finding, and animal or cell research does not show an effect in people. The same study can appear under more than one subject, so the number of records is not a count of independent studies. You can also search an exact DOI, PubMed ID, NCT or CRD number. How to read these records.
44 study records (showing up to 30 per record type)
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Registered trial NCT01754792 Completed (results not assessed here)Effects of Pinitol on Hidrocarbonated Metabolism Parameters in Diabetic, Impaired and Normal Fasting Glucose SubjectsCondition or outcome area: Type 2 Diabetes|Impaired Glucose Tolerance|Healthy2012-01 · Subject: Pinitol; (1R,2R,4R,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol; ZINC3978754; ZINC242463987; ononitol · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT01738763 Completed (results not assessed here)Effects of Different Doses of Pinitol on Carbohydrate Metabolism Parameters in Healthy SubjectsCondition or outcome area: Healthy|Insulin Sensitivity2011-07 · Subject: Pinitol; (1R,2R,4R,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol; ZINC3978754; ZINC242463987; ononitol · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT01708915 Phase 3 Completed (results not assessed here)Nonivamide/Nicoboxil Ointment in Acute Low Back PainCondition or outcome area: Acute Low Back Pain2012-10 · Subject: Nonivamide; nonyl vanillylamide; nonoyl vanillylamide; BRN 2144300; Nonivamida [INN-Spanish]; Spectrum_000311; Pelargonyl vanillylamide; 2444-46-4; Nonylic acid vanillylamide; Capsaicin synthetic · open the ingredient record · ClinicalTrials.gov
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Systematic review registration CRD42021230367 Registered protocol, no results here: Review OngoingThe efficacy of Shenghua Decoction supplementation after early medical abortion: a meta-analysis of randomized controlled trialsCondition or outcome area: Medical abortion, which recommended by the World Health Organization (WHO) using a combination of mifepristone followed by misoprostol, is increasingly being used to end an early pregnancy with approximately 98% effective, and considered as a safe, noninvasive, affordable and acceptable alternative worldwide over traditional dilatation and curettage. Despite excellent effectiveness and safety, incomplete abortion and excessive and prolonged uterine bleeding are among the major limitations in suc
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Systematic review registration CRD42020184465 Registered protocol, no results here: Review OngoingEffect of herbal medicine Shenghua decoction on uterine bleeding after early medical abortion: a protocol for a systematic review and meta-analysisCondition or outcome area: Unintended pregnancy is a problem that women encounter throughout their reproductive years. Medical termination of pregnancy has played a crucial role in providing access to safe, effective alternative worldwide by being noninvasive. However, the acceptability is not high as expected. Excessive and prolonged uterine bleeding is an important obstacle to get popularized. Herbal medicine Shenghua decoction is widely used throughout China and elsewhere in the world for the treating uterine bleeding
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Systematic review registration CRD42020209451 Registered protocol, no results here: Review OngoingA meta-analysis of effectiveness and safety of non-vitamin K oral anticoagulant compared to vitamin K antagonists in patients with left ventricular thrombosisCondition or outcome area: Left ventricular (LV) thrombi are associated with LV dysfunction. They can occur as a complication of acute myocardial infarction but may arise in nonischemic cardiomyopathies as well. Despite decades of study of LV thrombi, data of which we are aware regarding their treatment, particularly in the prevention of embolic events, are scarce. Non-vitamin K oral anticoagulant (NOACs) are highly selective direct factor Xa with oral bioavailability and rapid onset of action. They have predictable pharm2020-10-16 · Subject: Vitamin k; Vitamin K; 12001-79-5; 81818-54-4; Kephton; 2-methyl-3-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione; Vitamin K1(20); .alpha.-Phylloquinone; 2-methyl-3-(3,7,11,15-tetramethylhexadec-2-en-1-yl)naphthalene-1,4-dione; 2-methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)naphthalene-1,4-dione · open the ingredient record
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Systematic review registration CRD42020169620 Registered protocol, no results here: status not recordedEffects of resveratrol supplementation on vascular function: a systematic review and meta-analysisCondition or outcome area: Vascular function is regulated by many cell components, including vascular smooth muscle cells, endothelial cells, and adventitial tissues with infammatory cells, autonomic nervous system, and vasa vasorum. Changes in vascular function such as endothelial dysfunction and arterial stifness are key early features in the development of cardiovascular disease (CVD). Several noninvasive methods to assess vascular function have been developed, and two of them may be highlighted: fow-mediated dilationSubject: Trans-resveratrol; Resveratrol; resveratrol; 501-36-0; 3,4',5-Trihydroxystilbene; (E)-5-(4-Hydroxystyryl)benzene-1,3-diol; 3,5,4'-Trihydroxystilbene; (E)-resveratrol; Resvida; 3,4',5-Stilbenetriol · open the ingredient record
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Systematic review registration CRD42022314774 Registered protocol, no results here: Review OngoingIsosorbide Mononitrate Combined with Compound Danshen Dripping Pills in the Treatment of Coronary Heart Disease Angina Pectoris: A Systematic Review and Meta-analysisCondition or outcome area: 1.Coronary atherosclerotic heart disease refers to heart disease caused by myocardial ischemia, hypoxia or necrosis caused by coronary atherosclerosis that narrows, spasms or blocks the lumen of the coronary artery. According to the China Cardiovascular Health and Disease Report 2020:The prevalence of coronary heart disease in the population aged 15 and over is 12.3‰. The common clinical manifestations of coronary heart disease are angina pectoris (37.8%) and myocardial infarction (14.9%) .The m2022-04-07 · Subject: Isosorbide; 652-67-5; Isobide; Ismotic; Devicoran; Hydronol; Sorbid; (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol; (+)-D-Isosorbide; 1,4:3,6-Dianhydro-D-glucitol · open the ingredient record
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Systematic review registration CRD42018107227 Registered protocol, no results here: Review OngoingComparative efficacy and safety of dinoprostone, misoprostol and isosorbide mononitrate (IMN) for cervical ripening in outpatient settings: a systematic review and network meta-analysisCondition or outcome area: Try to find the best treatment for cervical ripening in outpatient setting.2018-08-28 · Subject: Isosorbide; 652-67-5; Isobide; Ismotic; Devicoran; Hydronol; Sorbid; (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol; (+)-D-Isosorbide; 1,4:3,6-Dianhydro-D-glucitol · open the ingredient record
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Systematic review registration CRD42016045587 Registered protocol, no results here: Review OngoingBeta-blockers alone or in combination with isosorbide mononitrate for secondary prevention of bleeding from gastro-esophageal varices in adults with cirrhosis and gastro-oesophageal varices [Cochrane Protocol]Condition or outcome area: The Cochrane Hepato-Biliary Group2016-08-09 · Subject: Isosorbide; 652-67-5; Isobide; Ismotic; Devicoran; Hydronol; Sorbid; (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol; (+)-D-Isosorbide; 1,4:3,6-Dianhydro-D-glucitol · open the ingredient record
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Systematic review registration CRD42015026556 Registered protocol, no results here: Review OngoingBeta-blockers alone or with isosorbide mononitrate for primary prevention in adults with cirrhosis and gastro-oesophageal varices [Cochrane Protocol]Condition or outcome area: The Cochrane Hepato-Biliary Group2015-09-24 · Subject: Isosorbide; 652-67-5; Isobide; Ismotic; Devicoran; Hydronol; Sorbid; (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol; (+)-D-Isosorbide; 1,4:3,6-Dianhydro-D-glucitol · open the ingredient record
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Systematic review registration CRD42022353413 Registered protocol, no results here: Review OngoingThe Hepatoprotective Potential of Mangiferin in Liver Diseases: a Meta Analysis2022-10-04 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record
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Systematic review registration CRD42021267839 Registered protocol, no results here: Review OngoingA systematic review of cannabidiol utilization for treatment in neurodevelopmental disordersCondition or outcome area: Cannabidiol (CBD) is a nonintoxicating phyto-cannabinoid present in the Cannabis sativa plant (VanDolah et al., 2019). A mounting body of evidence indicates that CBD can treat cognitive, social, communication, and behavioural symptoms observed in neurodevelopmental disorders. The endocannabinoid system has been linked to phenotypic features observed in neurodevelopmental disorders, including autism spectrum disorders (ASD), attention deficit hyperactivity disorder (ADHD), and Tourette’s syndrome2021-08-13 · Subject: Cannabidiol; 13956-29-1; (-)-Cannabidiol; (-)-trans-Cannabidiol; Epidiolex; CBD; (-)-CBD; GWP42003-P; CARDIOLRX; Cannabidiol [USAN] · open the ingredient record
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Systematic review registration CRD42020151001 Registered protocol, no results here: Review Completed publishedBerberine for diarrhea: a systematic review and meta-analysisCondition or outcome area: Diarrhea is defined as the passage of three or more loose or liquid stools per day (or more frequent passage than is normal for the individual). Diarrhea is a common symptom of intestinal tract infections and noninfectious problems. It can be caused by a variety of bacterial, viral parasitic organisms, improper diet and allergy, etc. The etiological diagnosis of diarrhea is based on medical history, symptoms, and routine testing (especially stool testing). Continued diarrhea leads to loss of flu2020-02-21 · Subject: Berberime; Berberine; berberine; 2086-83-1; Umbellatine; Berberin; Berbericine; Majarine; Thalsine; Umbellatin · open the ingredient record
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Publication PMID 34025405 Research model: Animal ExperimentBYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF-κB Pathway During ICH RecoveryCondition or outcome area: stroke; cerebral edema; Intracerebral hemorrhage; chronic inflammationFront Pharmacol · 2021 · Subject: Bu Yang Hai Wu Tang; 补阳还五汤; Bu Yang Huan Wu Decoction · open the formula record · DOI 10.3389/fphar.2021.632407
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Publication PMID 36290645 Research model: Animal & Cell ExperimentMaltol, a Natural Flavor Enhancer, Inhibits NLRP3 and Non-Canonical Inflammasome ActivationCondition or outcome area: inflammatory diseasesAntioxidants (Basel) · 2022 · Subject: Vetol; Maltol; MALTOL; 118-71-8; 3-Hydroxy-2-methyl-4-pyrone; 3-Hydroxy-2-methyl-4H-pyran-4-one; Larixinic acid; Palatone; Talmon; Larixic acid · open the ingredient record · DOI 10.3390/antiox11101923
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Publication PMID 35708264 Research model: Cell ExperimentUrsolic acid inhibits the activation of smoothened-independent non-canonical hedgehog pathway in colorectal cancer by suppressing AKT signaling cascadeCondition or outcome area: multiple malignancies; colorectal cancer; cancersPhytother Res · 2022 · Subject: Ursolic acid; Ursolic Acid; 77-52-1; Prunol; Malol; Urson; 3beta-Hydroxyurs-12-en-28-oic acid; Micromerol; (3beta)-3-Hydroxyurs-12-en-28-oic acid; (+)-Ursolic acid · open the ingredient record · DOI 10.1002/ptr.7523
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Publication PMID 34417574 Research model: Animal ExperimentTetrandrine alleviates silicosis by inhibiting canonical and non-canonical NLRP3 inflammasome activation in lung macrophagesCondition or outcome area: attenuated silicosis; inflammation; silicosis; Silicosis; silicosis-associated inflammation; fibrosisActa Pharmacol Sin · 2021 · Subject: Tetrandrine; 518-34-3; D-Tetrandrine; (+)-Tetrandrine; Tetrandrin; Fanchinine; Sinomenine A; (S,S)-Tetrandrine; hanjisong; DL-Tetrandine · open the ingredient record · DOI 10.1038/s41401-021-00693-6
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Publication PMID 31678492 Research model: Cell ExperimentInduction of an MLKL mediated non-canonical necroptosis through reactive oxygen species by tanshinol A in lung cancer cellsCondition or outcome area: ferroptosis; lung cancer; programmed necrosis; pyroptosis; necroptosisBiochem Pharmacol · 2020 · Subject: Tanshinol a; Tanshinol A; 6-(Hydroxymethyl)-1-methylphenanthro[1,2-b]furan-10,11-dione; 189290-28-6 · open the ingredient record · DOI 10.1016/j.bcp.2019.113684
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Publication PMID 36559338 Research model: Cell ExperimentEffects of Mangiferin on LPS-Induced Inflammation and SARS-CoV-2 Viral Adsorption in Human Lung CellsCondition or outcome area: mitochondrial dysfunction; COVID-19 infectionPharmaceutics · 2022 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.3390/pharmaceutics14122845
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Publication PMID 36499655 Research model: Animal ExperimentMangiferin Ameliorates Obesity-Associated Inflammation and Autophagy in High-Fat-Diet-Fed Mice: In Silico and In Vivo ApproachesCondition or outcome area: obesity; metabolic diseases; metabolic syndrome; tumor; high-fat-diet; obese; metabolic disordersInt J Mol Sci · 2022 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.3390/ijms232315329
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Publication PMID 36408274 Research model: Animal ExperimentMangiferin promotes osteogenic differentiation and alleviates osteoporosis in the ovariectomized mouse via the AXL/ERK5 pathwayCondition or outcome area: osteoporosisFront Pharmacol · 2022 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.3389/fphar.2022.1028932
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Publication PMID 36332683 Research model: Cell ExperimentMangiferin alleviates hyperglycemia-induced endothelial impairment via Nrf2 signaling pathwayEur J Pharmacol · 2022 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.1016/j.ejphar.2022.175359
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Publication PMID 36077522 Research model: Cell ExperimentAnti-Inflammation and Anti-Pyroptosis Activities of Mangiferin via Suppressing NF-κB/NLRP3/GSDMD Signaling CascadesCondition or outcome area: pyroptosisInt J Mol Sci · 2022 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.3390/ijms231710124
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Publication PMID 35778992 Research model: Cell ExperimentMangiferin prevents hepatocyte epithelial-mesenchymal transition in liver fibrosis via targeting HSP27-mediated JAK2/STAT3 and TGF-β1/Smad pathwayCondition or outcome area: fibrosis; liver injury; liver fibrosis; hepatic fibrosis; liver cirrhosisPhytother Res · 2022 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.1002/ptr.7549
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Publication PMID 35752080 Research model: Animal ExperimentMangiferin, a natural glucoxilxanthone, inhibits mitochondrial dynamin-related protein 1 and relieves aberrant mitophagic proteins in mice model of Parkinson's diseaseCondition or outcome area: motor deficiency; neurodegenerative disease; Parkinson's disease; mitochondrial dysfunctionPhytomedicine · 2022 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.1016/j.phymed.2022.154281
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Publication PMID 35721155 Research model: Cell ExperimentMangiferin Alleviates Postpartum Depression-Like Behaviors by Inhibiting MAPK Signaling in MicrogliaCondition or outcome area: mental health disorder; Postpartum depressionFront Pharmacol · 2022 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.3389/fphar.2022.840567
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Publication PMID 33923922 Research model: Cell ExperimentMangiferin Inhibits Apoptosis in Doxorubicin-Induced Vascular Endothelial Cells via the Nrf2 Signaling PathwayInt J Mol Sci · 2021 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.3390/ijms22084259
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Publication PMID 33523605 Research model: Animal & Cell ExperimentMangiferin prevents myocardial infarction-induced apoptosis and heart failure in mice by activating the Sirt1/FoxO3a pathwayCondition or outcome area: Myocardial infarction; heart failure; cardiovascular diseasesJ Cell Mol Med · 2021 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.1111/jcmm.16329
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Publication PMID 32969440 Research model: Animal & Cell ExperimentMangiferin protects against alcoholic liver injury via suppression of inflammation-induced adipose hyperlipolysisCondition or outcome area: alcoholic liver disease; alcoholic liver injury; ethanol-induced liver injury; Adipose dysfunction; liver injuryFood Funct · 2020 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.1039/d0fo01436b
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Publication PMID 32417366 Research model: Cell ExperimentMangiferin induces the expression of a thermogenic signature via AMPK signaling during brown-adipocyte differentiationCondition or outcome area: obesityFood Chem Toxicol · 2020 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.1016/j.fct.2020.111415
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Publication PMID 32408566 Research model: Animal ExperimentMangiferin Alleviates Ovalbumin-Induced Allergic Rhinitis via Nrf2/HO-1/NF-κB Signaling PathwaysCondition or outcome area: nasal mucosa inflammation; nasal mucosal inflammation; allergic rhinitisInt J Mol Sci · 2020 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.3390/ijms21103415
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Publication PMID 32353588 Research model: Animal ExperimentMangiferin activates Nrf2 to attenuate cardiac fibrosis via redistributing glutaminolysis-derived glutamateCondition or outcome area: metabolic disorders; Cardiac injury; impaired heart function; transverse aortic constriction; myocardial systolic and diastolic dysfunction; cardiac fibrosis; fibrosisPharmacol Res · 2020 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.1016/j.phrs.2020.104845
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Publication PMID 32289346 Research model: Cell ExperimentPINK1-PRKN mitophagy suppression by mangiferin promotes a brown-fat-phenotype via PKA-p38 MAPK signalling in murine C3H10T1/2 mesenchymal stem cellsCondition or outcome area: obesity; diabetes; cancerMetabolism · 2020 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.1016/j.metabol.2020.154228
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Publication PMID 32158448 Research model: Animal & Cell ExperimentMangiferin Attenuates LPS/D-GalN-Induced Acute Liver Injury by Promoting HO-1 in Kupffer CellsCondition or outcome area: hepatic encephalopathy; hepatic failure; Acute liver injury; acute liver injury; inflammatory response syndrome; multiorgan failureFront Immunol · 2020 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.3389/fimmu.2020.00285
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Publication PMID 32119962 Research model: Animal ExperimentMangiferin exert cardioprotective and anti-apoptotic effects in heart failure induced ratsCondition or outcome area: heart failureLife Sci · 2020 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.1016/j.lfs.2020.117476
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Publication PMID 32116724 Research model: Animal ExperimentMangiferin Ameliorates Hyperuricemic Nephropathy Which Is Associated With Downregulation of AQP2 and Increased Urinary Uric Acid ExcretionCondition or outcome area: hyperuricemic nephropathy; Hyperuricemia; inflammation; renal inflammation; endothelial dysfunction; renal dysfunction; fibrosis; kidney injuryFront Pharmacol · 2020 · Subject: Mangiferin; 4773-96-0; Chinonin; Alpizarin; Hedysarid; Aphloiol; Chinomin; Alpizarine; UNII-1M84LD0UMD; 1M84LD0UMD · open the ingredient record · DOI 10.3389/fphar.2020.00049
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Publication PMID 30412793 Research model: Cell ExperimentFerutinin directs dental pulp-derived stem cells towards the osteogenic lineage by epigenetically regulating canonical Wnt signalingCondition or outcome area: bone deterioration; systemic disease; Osteoporosis; osteoporosisBiochim Biophys Acta Mol Basis Dis · 2020 · Subject: Ferutinin; Ferutinine; 41743-44-6; Jaeschkeanadiol p-hydroxybenzoate; 4-Oxy-6-(4-oxybezoyloxy)dauc-8,9-en; [(3R,3aS,4S,8aR)-3-hydroxy-6,8a-dimethyl-3-propan-2-yl-1,2,3a,4,5,8-hexahydroazulen-4-yl] 4-hydroxybenzoate; Tefestrol; Benzoic acid, 4-hydroxy-, (3R,3aS,4S,8aR)-1,2,3,3a,4,5,8,8a-octahydro-3-hydroxy-6,8a-dimethyl-3-(1-methylethyl)-4-azulenyl ester; Benzoic acid, 4-hydroxy-, 1,2,3,3a,4,5,8,8a-octahydro-3-hydroxy-6,8a-dimethyl-3-(1-methylethyl)-4-azulenyl ester, (3R-(3alpha,3abeta,4beta,8aal · open the ingredient record · DOI 10.1016/j.bbadis.2018.10.032
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Publication PMID 35766262 Research model: Animal ExperimentColchicine Ameliorates Dilated Cardiomyopathy Via SIRT2-Mediated Suppression of NLRP3 Inflammasome ActivationCondition or outcome area: heart failure; Dilated cardiomyopathy; fibrosis; dilated cardiomyopathy; nonischemic heart failureJ Am Heart Assoc · 2022 · Subject: Colchicine; 64-86-8; Colchisol; Colchicinum; Colchicin; Colchicina; Colchineos; Condylon; Colcin; Colsaloid · open the ingredient record · DOI 10.1161/JAHA.122.025266
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Publication PMID 35912256 Research model: Cell ExperimentOnonin Shows Anticancer Activity Against Laryngeal Cancer via the Inhibition of ERK/JNK/p38 Signaling PathwayCondition or outcome area: laryngeal cancer; laryngeal cancer Hep-2; head and neck tumor; Laryngeal cancerFront Oncol · 2022 · Subject: Ononin; 486-62-4; Formononetin glucoside; Formononetin 7-O-glucoside; formononetin-7-O-glucoside; Ononoside; 4'-Methoxyisoflavone-7-O-beta-D-glucopyranoside; Formononetin-7-O-beta-D-glucopyranoside; CHEBI:7775; UNII-Z0Z637970U · open the ingredient record · DOI 10.3389/fonc.2022.939646
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Publication PMID 33734250 Research model: Cell ExperimentImmunomodulatory effect of Noni fruit and its isolates: insights into cell-mediated immune response and inhibition of LPS-induced THP-1 macrophage inflammationCondition or outcome area: paw edemaFood Funct · 2021 · Subject: Hai Bin Mu Ba Ji; 海滨木巴戟; Indianmulberry; Morinda Citrifolia · open the herb record · DOI 10.1039/d0fo03402a
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Publication PMID 33182564 Research model: Animal ExperimentTherapeutic Effects of Morinda citrifolia Linn. (Noni) Aqueous Fruit Extract on the Glucose and Lipid Metabolism in High-Fat/High-Fructose-Fed Swiss MiceNutrients · 2020 · Subject: Hai Bin Mu Ba Ji; 海滨木巴戟; Indianmulberry; Morinda Citrifolia · open the herb record · DOI 10.3390/nu12113439
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Publication PMID 32298014 Research model: Animal ExperimentMorinda citrifolia (Noni) fruit juice promotes vascular endothelium function in hypertension via glucagon-like peptide-1 receptor-CaMKKβ-AMPK-eNOS pathwayCondition or outcome area: hypertensionPhytother Res · 2020 · Subject: Hai Bin Mu Ba Ji; 海滨木巴戟; Indianmulberry; Morinda Citrifolia · open the herb record · DOI 10.1002/ptr.6685
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Publication PMID 31963703 Research model: Animal ExperimentFermented Morinda citrifolia (Noni) Alleviates DNCB-Induced Atopic Dermatitis in NC/Nga Mice through Modulating Immune Balance and Skin Barrier FunctionCondition or outcome area: AD lesions; inflammatory diseases; AD-like skin lesions; atopic dermatitis; dermatitisNutrients · 2020 · Subject: Hai Bin Mu Ba Ji; 海滨木巴戟; Indianmulberry; Morinda Citrifolia · open the herb record · DOI 10.3390/nu12010249