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Support skin as it ages: a wide-brimmed straw hat, a tube of sunscreen without a label, a small glass jar of face cream and a sprig of green leaves on a sunlit wooden table

Skin & Hair

Skin Aging, Wrinkles and Uneven Skin Tone

Skin changes with time through natural aging and through a lifetime of sun exposure, and fine lines, age spots and uneven tone are common and usually harmless. This page sorts the evidence on what may slow or soften those changes (sun protection first) and when a changing spot needs a clinician; routines, dry skin, sun-protection details, texture and tone each have their own pages.

General information, not medical advice. Last updated October 31, 2026. Written by the AlternativeMed editorial team. Not medically reviewed.

Start here

  • Protect your skin from the sun every day: shade at midday, covering clothing, and a broad-spectrum sunscreen used as directed. It is the best-supported step for slowing skin aging.
  • If you smoke, know that smoking is a recognized risk factor for skin aging; ask a pharmacist or clinician about support to stop.
  • Check your skin from time to time, and see a doctor about any mole or spot that is new, changing, itchy, bleeding or crusty instead of treating it yourself.

Be careful with

  • Do not treat a new or changing dark spot with creams, lightening products or home remedies before a clinician has looked at it.
  • Prescription retinoid-type creams and some other active skin products can irritate and are not for everyone; the sources read for this page did not detail irritation rates or pregnancy safety, so ask a pharmacist or dermatologist, especially in pregnancy or breastfeeding.
  • Supplements sold for skin are not a substitute for sunscreen, and they can interact with medicines; check with a pharmacist first. Do not stop a prescribed medicine or skin treatment on your own.

Get help when

  • A mole that has changed size, shape or colour, or is painful, itchy, inflamed, bleeding or crusty.
  • A new or unusual mark on the skin that has not gone away after a few weeks, including on the palms of the hands or soles of the feet.
  • A dark area under a nail that was not caused by an injury.
  • Swelling of the lips or face, trouble breathing, or a rapidly spreading painful red rash after a product or medicine: treat this as an emergency and call your local emergency number.

About Skin Aging, Wrinkles and Uneven Skin Tone

What this goal means

This goal is about helping skin look and stay as healthy as possible as the years go by: fewer new lines, spots and roughness from sun and lifestyle, and sensible care for the changes that are already there. The FDA lists sunburn, skin cancer and early skin aging among the risks of overexposure to the sun.

A systematic review of skin aging risk factors identified age, gender, ethnicity, air pollution, nutrition, smoking and sun exposure. Some of these cannot be changed, but sun exposure and smoking can.

1,2

What it can feel like

Common experiences are fine lines and wrinkles, a loss of firmness, dull or uneven tone, dark spots (sun spots, also called lentigines) and a rougher feel. These are normal and usually harmless. They are a cosmetic concern, not a disease, and how much they matter is personal.

3,4

What can contribute

Natural aging (intrinsic) and environmental influences such as sun, smoking and air pollution (extrinsic) both play a part. In a randomized trial, people who used sunscreen daily showed less skin aging over 4.5 years than those who used it only when they chose to, which supports sun exposure as a contributor you can act on.

Diet and nutrition appear in the risk-factor review too, but the evidence on food and appearance is limited (see the food section).

2,5,6

Conditions that can look similar

Dark or changing marks can be harmless age spots, but a mole or spot that changes can be a sign of melanoma, so it needs to be examined. Rashes, dryness, itch and redness are separate topics: see the linked pages for dry skin, sensitive skin and rosacea instead of assuming they are part of aging.

7,8

Realistic expectations

Sun protection can slow further damage; creams and supplements that help usually produce modest changes over weeks to months, not a reversal. The tretinoin trials reviewed here reported improvement from as early as 1 month, and the vitamin C review said long-term use may be needed to see noticeable change.

Skin changes of age are normal. Good evidence supports protecting the skin you have, while claims of erasing wrinkles with a pill or a cream should be treated with caution.

3,4

Who this applies to

Adults noticing lines, spots or uneven tone, and younger adults who want to slow the process. Babies, children, pregnancy and people with skin conditions have extra needs; see the cautions below.

9

Related conditions and symptoms

Acne → Rosacea → Psoriasis → Eczema → Contact dermatitis →

A manageable starting plan

An educational starting point, not a personal prescription. Adjust it to your own situation and any advice from your clinician.

Your first actions

  • Make sun protection a daily habit: shade at midday, covering clothes, broad-spectrum sunscreen applied generously and reapplied.
  • If you smoke, ask for stop-smoking support.
  • Check your skin regularly and book a visit for any changing spot.
  • Add one gentle routine step (for example a moisturiser with sunscreen) before trying active products.

Optional additions

  • Try a non-prescription retinol or vitamin C product, introduced slowly after a patch test.
  • Ask a dermatologist about prescription options if lines or spots bother you.
  • If you try collagen or another supplement, treat it as an uncertain extra.

What to track

  • Photos in the same light every 4 to 6 weeks.
  • Any irritation, redness or new product you started.
  • Any mole or spot that changes.

When to reassess

Give a new skin-care product several weeks to months before judging it, and stop it if it irritates. See a clinician if you see no change from approaches you were advised, or at once for a changing mole.

When to seek professional support

  • See a GP or dermatologist for a changing mole, a non-healing spot or any concern.
  • Ask a pharmacist before combining active skin products or supplements with medicines.

What helps

Ordered by how well the research supports each step. Evidence strength is shown on every card; precautions sit next to the advice.

Start here

Daily sun protection (sunscreen, shade, clothing)

Moderate certainty

Addresses: Slows further sun-related skin aging

Why it may help: In a randomized trial of 903 adults under 55, skin aging was 24% less in the daily broad-spectrum sunscreen group than in the discretionary-use group over 4.5 years (relative odds 0.76, 95% CI 0.59 to 0.98). The authors noted some missing outcome data and modest power. The FDA advises limiting time in the sun when it is most intense, covering up, and using broad-spectrum sunscreen with SPF 15 or higher regularly and as directed. The NHS advises at least SPF 30 with at least 4-star UVA protection.

How to apply it: Use enough, apply before going out, and reapply at least every 2 hours and after swimming or sweating. Combine with shade and clothing instead of relying on sunscreen alone.

Who it may suit: Almost all adults; extra care if you burn easily, have many moles or a family history of skin cancer.

Precautions: Infants under 6 months should be kept out of direct sun and, per the FDA, sunscreen is not recommended for them. Ask a doctor before using sunscreen on a baby. Sunscreen details and reapplication have their own page.

5,1,9

Protect Your Skin From Sun Damage → Skin care basics →

Do not tan, and avoid sunbeds and sunlamps

High certainty

Addresses: Avoids avoidable UV damage

Why it may help: The NHS says there is no safe or healthy way to get a tan, and a tan does not protect the skin from the sun's harmful effects. Its mole guidance says not to use sunlamps or sunbeds because they use UV light.

How to apply it: Choose shade, covering clothing and sunglasses; if you like colour, ask a pharmacist about sunless options instead of exposure.

Who it may suit: Everyone, especially people with fair skin or many moles.

Precautions: Balance sun protection with vitamin D needs by talking to a clinician if you rarely go outdoors.

9,7

Do not smoke (or get support to stop)

Moderate certainty

Addresses: Removes a recognized skin aging risk factor

Why it may help: A systematic review and meta-analysis of skin aging risk factors listed smoking among seven notable factors (age, gender, ethnicity, air pollution, nutrition, smoking, sun exposure). The review summarizes associations; it does not say how fast skin recovers after stopping.

How to apply it: If you smoke, ask a pharmacist or clinician about stop-smoking support. Any quitting is worthwhile for health reasons beyond skin.

Who it may suit: Smokers and people around heavy smoke.

Precautions: Do not stop or change a prescribed medicine for this reason without advice.

2

Regular skin checks

High certainty

Addresses: Finds changing spots early

Why it may help: The NHS says to check moles regularly for changes, to use a mirror or ask someone to check areas you cannot see, and that finding a melanoma early can make it easier to treat.

How to apply it: Look for uneven shape or edges, a mix of colours, size (often more than 6 mm), and any change over time; also swollen, sore, bleeding, itchy or crusty spots.

Who it may suit: Everyone, especially with many moles or a family history of skin cancer.

Precautions: This is not a self-diagnosis; a clinician decides what a mark is.

8,7

Skin and hair safety →

Additional options

Over-the-counter retinol

Moderate certainty

Addresses: May soften lines and improve skin appearance

Why it may help: A systematic review of 32 studies (1,236 patients; 20 randomized trials) gave retinol and vitamin C a Grade A recommendation for anti-aging, and reported favorable safety profiles with few significant adverse events. The reviewers noted a limited number of randomized trials and a need for long-term data.

How to apply it: Cosmetic retinol products are used on the skin in the evening in many routines; follow the label and introduce slowly.

Who it may suit: Adults with fine lines who accept a slow, modest effect.

Precautions: Pregnancy and breastfeeding: the sources read did not detail retinoid safety there, so ask a pharmacist or dermatologist first. Can irritate; always use sunscreen by day.

10

Natural skin-care ingredients → Pregnancy and breastfeeding safety →

Topical vitamin C

Low certainty

Addresses: May lighten spots and smooth skin

Why it may help: A systematic review of 7 publications (139 volunteers) found treated skin appeared smoother and less wrinkled, with significant lightening on objective pigment measures; hydration improved equally with vitamin C and placebo. The authors said more studies are needed to confirm results and the ideal concentration.

How to apply it: Used as a serum or cream; the review suggests long-term use may be needed for noticeable change.

Who it may suit: Adults with uneven tone or mild sun damage.

Precautions: Can sting or irritate; patch-test first on a small area.

4,10

Vitamin C →

Prescription topical retinoid (clinician-led)

Moderate certainty

Addresses: Improves wrinkling, mottled colour and sun spots

Why it may help: A systematic review of 7 randomized trials found topical tretinoin consistently improved wrinkling, mottled hyperpigmentation, sallowness and lentigines, as early as 1 month, lasting to 24 months in some studies. The reviewers noted different formulas and outcome measures made the evidence uneven.

How to apply it: This is a prescription medicine; a clinician decides whether it suits you and how to use it.

Who it may suit: Adults with photoaging who want a medical option.

Precautions: Prescription-only; ask a clinician about irritation, sun sensitivity and pregnancy, which the sources read did not detail.

3

Natural skin-care ingredients →

Still being studied

Oral polyphenol, carotenoid and Polypodium leucotomos supplements

Low certainty

Addresses: May add a little sun-damage protection

Why it may help: A review of 47 human studies found the greatest evidence of photoprotection for polyphenols, carotenoid-based supplements and Polypodium leucotomos, and the weakest for isolated vitamins or coenzyme Q. The reviewers said evidence is limited by small samples and short duration.

How to apply it: Not a replacement for sunscreen; no dose is given here because the review said optimal dosing is not established.

Who it may suit: Adults who already protect their skin and are curious about extras.

Precautions: Check with a pharmacist if you take medicines; supplements vary by product. Pregnancy and children: ask first.

11

Antioxidants and skin aging → Coenzyme Q10 →

Collagen supplements

Mixed findings

Addresses: Small, uncertain gains in skin hydration and elasticity

Why it may help: A 2021 meta-analysis of 19 randomized trials (1,125 participants, 95% women) favored hydrolyzed collagen for hydration, elasticity and wrinkles. A later meta-analysis of 23 trials (1,474 participants) found benefit overall, but not in trials without pharmaceutical funding or in high-quality trials, and concluded there is currently no clinical evidence to support collagen supplements for preventing or treating skin aging.

How to apply it: If you try it, judge it after a few months and do not expect wrinkle removal.

Who it may suit: Adults who accept uncertain benefit.

Precautions: Products vary; check allergy sources (marine, bovine) and medicines with a pharmacist.

12,13

Collagen, biotin and beauty supplements → Collagen →

Food & nutrition

What food can and cannot do for ageing skin

A systematic review of 27 studies of dietary intake and appearance found that observational studies showed associations between diet and skin colour and aging, and that most intervention studies tested supplements rather than food; only one examined actual food intake. The authors called for higher-quality randomized trials. This means no particular food has been shown to reverse skin aging.

A balanced diet supports health generally. In the sunscreen trial, beta-carotene supplements had no overall effect on skin aging. See the nutrition page for skin, hair and nails for deficiency checks.

Carotenoid- and polyphenol-rich foods (colourful fruit and vegetables, green tea)

Very low certainty

Addresses: Possible small contribution to sun resilience

Why it may help: The supplement review found the best photoprotective evidence for polyphenols and carotenoids, but in supplement form and in small, short studies; the sources read did not test whether food gives the same effect.

How to apply it: Eat a varied diet with plenty of colourful plants; this is a general habit, not a skin treatment.

Who it may suit: Most adults.

Precautions: Do not use food as a substitute for sunscreen; green tea extract products can interact with medicines, so ask a pharmacist.

11

Green tea → Nutrition for skin and hair →

6,5

Remedies & supplements

Traditional use, laboratory findings and human trials are kept apart. "Natural" does not mean safe.

Retinol (non-prescription topical)

Moderate certainty

Studied form and route: Cosmetic cream or serum

Intended outcome: Finer lines and smoother skin

Human evidence: Retinol received a Grade A recommendation for anti-aging in a systematic review of 32 studies; bakuchiol and some other ingredients received Grade C and the rest were inconclusive.

Traditional use: Not a traditional remedy; a modern cosmetic ingredient.

Laboratory findings: The tretinoin review noted that retinoids regulate skin cell growth and induce new collagen formation, a mechanism claim rather than proof of benefit.

Limits: Few randomized trials; long-term data are needed.

Interactions and precautions: May irritate; use sunscreen by day. Pregnancy and breastfeeding: ask a clinician or pharmacist.

10,3

Natural skin-care ingredients →

Topical vitamin C

Low certainty

Studied form and route: Serum or cream

Intended outcome: Smoother skin and lighter spots

Human evidence: A review of 7 trials (139 volunteers) reported smoother, less wrinkled skin and measurable lightening; hydration did not differ from placebo.

Traditional use: None relevant.

Laboratory findings: Vitamin C is present in high concentrations in normal skin and is described as regulating collagen production; this is background, not proof of effect.

Limits: Small studies; ideal concentration unknown.

Interactions and precautions: Patch-test; can sting.

4,10

Vitamin C →

Collagen peptides

Mixed findings

Studied form and route: Oral powder or capsule

Intended outcome: Skin hydration and elasticity

Human evidence: One meta-analysis of 19 trials favored collagen; a later one of 23 trials found no effect in non-industry-funded and high-quality trials.

Traditional use: Bone broth and gelatin foods are traditional, but the studies here tested hydrolyzed collagen products.

Laboratory findings: Not covered in the sources read.

Limits: Funding bias and study quality drive the result.

Interactions and precautions: Check source allergies and medicines with a pharmacist.

12,13

Collagen → Collagen, biotin and beauty supplements →

Polypodium leucotomos, carotenoids and polyphenols

Low certainty

Studied form and route: Oral supplements

Intended outcome: Photoprotection (less sun damage)

Human evidence: A review of 47 human studies found the greatest evidence for these three, the weakest for isolated vitamins and coenzyme Q; studies were small and short.

Traditional use: Polypodium is a fern used in traditional medicine; the sources read did not describe that history.

Laboratory findings: Photoprotective effects have been shown in animal and in vitro studies.

Limits: Optimal dose and duration are not established.

Interactions and precautions: Not a sunscreen substitute; check medicines with a pharmacist.

11

Antioxidants and skin aging →

Therapies & care

For wrinkles, spots and tone, established professional care is led by a GP or dermatologist, who can examine a changing spot, discuss prescription creams or other in-clinic options, and advise on pregnancy and medicines. This page does not recommend medicines or doses, and you should not stop a prescribed treatment on your own.

Dermatologist or GP skin check

High certainty

Professional care A clinician examines a mole or spot, asks about family history and may take a photo for a specialist; a referral can follow if melanoma is suspected.

Who it may suit: Anyone with a new or changing mole or mark.

Precautions: Do not delay for creams or home remedies.

8,7

Skin and hair safety →

Prescription topical retinoid

Moderate certainty

Medical treatment A clinician-prescribed vitamin A-derived cream; a review of 7 randomized trials of topical tretinoin reported improved wrinkling, mottled hyperpigmentation and sun spots.

Who it may suit: Adults whose photoaging bothers them and who want medical treatment.

Precautions: Ask about irritation, sun sensitivity and pregnancy.

3

What to avoid

Habits, products and claims that can get in the way. Never stop a prescribed medicine without talking to the professional who prescribed it.

Risks that apply to most people

Sunburn and deliberate tanning

High certainty

Why: The NHS says sunburn increases skin cancer risk, and that a tan does not protect your skin from harmful effects of the sun. The FDA lists early skin aging among the risks of overexposure.

Who it applies to: Everyone; fair skin and many moles raise the stakes.

Try instead: Use shade, clothing, sunglasses and sunscreen, and never burn.

9,1

Sunbeds and sunlamps

High certainty

Why: The NHS mole guidance says not to use sunlamps or sunbeds, because they use UV light, which can increase the chance of a mole becoming cancerous.

Who it applies to: Anyone.

Try instead: Choose shade and covering clothing.

7

Smoking

Moderate certainty

Why: Smoking is listed as one of seven notable risk factors for skin aging in a systematic review.

Who it applies to: Smokers.

Try instead: Ask for support to stop smoking.

2

Personal triggers to check

Midday sun

Moderate certainty

Why: The FDA says rays are most intense between 10 a.m. and 2 p.m.; the NHS says 11am to 3pm in the UK from March to October.

Who it applies to: People outdoors at midday, including on cloudy days.

Try instead: Seek shade and cover up when the sun is strongest.

1,9

Products that need caution

Sunscreen that is not broad spectrum or has low SPF

High certainty

Why: The FDA says sunscreens that are not broad spectrum or have an SPF below 15 carry a warning that they have been shown only to help prevent sunburn, not skin cancer or early skin aging.

Who it applies to: Anyone choosing a sunscreen.

Try instead: Choose broad-spectrum SPF 15 or higher (FDA) or SPF 30 with 4-star UVA (NHS) and use enough.

1,9

Skincare actives used without a patch test

Low certainty

Why: Active creams can irritate, and the sources read for this page did not detail irritation rates for retinoid-type products.

Who it applies to: People with sensitive or reactive skin.

Try instead: Patch-test, introduce one product at a time and ask a pharmacist or dermatologist.

10,3

Care for Sensitive Skin →

Unsupported claims

"Collagen pills erase wrinkles"

Evidence against

Why: A later meta-analysis found no significant effect in non-industry-funded or high-quality trials and concluded there is no clinical evidence to support collagen supplements for skin aging.

Who it applies to: Anyone considering beauty supplements.

Try instead: Rely on sun protection and treatments with better evidence; treat collagen as an uncertain extra.

13

"Higher SPF means you can stay in the sun for longer"

High certainty

Why: The FDA says SPF is not directly related to time in the sun but to the amount of solar exposure, and all sunscreens wash off. The NHS says not to spend longer in the sun than you would without sunscreen.

Who it applies to: Sunscreen users.

Try instead: Reapply at least every two hours and keep using shade and clothing.

1,9

"Antioxidant pills replace sunscreen"

Low certainty

Why: A supplement review found the weakest evidence for isolated vitamins or coenzyme Q and said evidence is limited by small, short studies; in the sunscreen trial, beta-carotene had no overall effect on skin aging.

Who it applies to: Supplement users.

Try instead: Keep sunscreen first; treat supplements as optional.

11,5

Common mistakes

Self-treating a new or changing dark spot

High certainty

Why: The NHS lists spots that change, itch, bleed or crust as reasons to see a GP, and says finding melanoma early can make it easier to treat.

Who it applies to: Anyone with a new or changing spot.

Try instead: Have it examined before using any cream or home remedy.

7,8

Using too little sunscreen

Moderate certainty

Why: The NHS says most people do not apply enough and gives a guide of around 6 to 8 teaspoons for the whole body; the FDA says an adult needs at least one ounce.

Who it applies to: Most sunscreen users.

Try instead: Apply generously to all exposed skin including ears, neck and the backs of hands.

9,1

Evidence & safety

What the research shows

The best-supported step is sun protection: a randomized trial found less skin aging with daily sunscreen, and agencies recommend shade, clothing and broad-spectrum sunscreen. Prescription topical tretinoin has seven trials behind it, and retinol and vitamin C have promising but limited evidence. Oral supplements for sun damage and collagen have weaker, small or mixed evidence and do not replace sunscreen.

Limits of the evidence

  • The sunscreen trial had some missing outcome data and modest power.
  • The retinoid trials used different formulas and outcome measures.
  • The cosmeceutical, vitamin C and supplement reviews cite few randomized trials and small, short studies.
  • Collagen results depend on funding source and study quality.
  • The sources read did not detail irritation rates or pregnancy safety for retinoid-type products.

Precautions and interactions

  • Patch-test new products and introduce one at a time.
  • Check supplements and active creams with a pharmacist if you take medicines.
  • Never stop a prescribed medicine or treatment because of a skin-care product.

Life-stage considerations

  • Pregnancy and breastfeeding: ask a pharmacist or dermatologist before retinoid-type products or supplements; see the pregnancy safety page.
  • Babies and children: the NHS advises keeping babies under 6 months out of direct sunlight; the FDA does not recommend sunscreen under 6 months. Children's skin is more sensitive.
  • Older adults and darker skin: darker skin has some natural protection, but sun protection and skin checks still apply; ask a clinician about spots that change.

Warning signs

  • A mole that changes size, shape or colour, or is painful, itchy, inflamed, bleeding or crusty.
  • A new or unusual mark that has not gone away after a few weeks.
  • A dark area under a nail not caused by injury.
  • Swelling of the lips or face or trouble breathing after a product: seek emergency care.

Claim checks

Daily sunscreen slows skin aging

Moderate certainty

Supported by one well-designed randomized trial: 24% less skin aging over 4.5 years versus discretionary use.

5

Collagen supplements prevent or reverse wrinkles

Mixed findings

Mixed to against: positive overall, but no significant effect in non-industry-funded or high-quality trials.

12,13

Antioxidant supplements protect against sun damage

Low certainty

Limited: some evidence for polyphenols, carotenoids and Polypodium leucotomos in small, short studies; weakest for isolated vitamins or coenzyme Q. Beta-carotene had no overall effect on skin aging in the sunscreen trial.

11,5

A tan protects your skin

Evidence against

Against: the NHS says there is no safe or healthy way to get a tan and a tan does not protect skin from the sun's harmful effects.

9

Questions people ask

What is the best thing for wrinkles?

The research best supports sun protection and prescription tretinoin; retinol and vitamin C have promising evidence. See the evidence labels above.

Does daily sunscreen really slow aging?

In a randomized trial of 903 adults under 55, skin aging was 24% less in the daily sunscreen group than in the discretionary group over 4.5 years.

Do anti-aging supplements work?

For sun-related skin damage the evidence is limited and mostly small and short-term; they do not replace sunscreen.

Does collagen work for wrinkles?

Results are mixed. One meta-analysis favored it, but a later one found no significant effect in non-industry-funded or high-quality trials.

Is a new dark spot normal?

Many are harmless, but a spot that is new, changing, bleeding or itchy should be checked by a clinician.

Which SPF should I use?

The FDA says broad spectrum with SPF 15 or higher; the NHS says at least SPF 30 with at least 4-star UVA protection. Use enough and reapply.

How often should I reapply sunscreen?

At least every two hours, and after swimming, sweating or towel drying.

Is it safe to use retinol in pregnancy?

The sources read did not detail pregnancy safety for retinoid-type products, so ask a pharmacist or dermatologist first.

Does smoking age the skin?

A systematic review listed smoking among seven notable risk factors for skin aging.

When should I see a doctor about a spot?

See a GP for a mole that has changed, is painful, itchy, inflamed, bleeding or crusty, or a new unusual mark that has not gone away after a few weeks.

References

  1. FDA. Sunscreen: how to help protect your skin from the sun. Read 2026-10-31. source
  2. Defining skin aging and its risk factors: a systematic review and meta-analysis. Sci Rep 2021. PMID 34764376. Read 2026-10-31. source
  3. Sitohang IBS et al. Topical tretinoin for treating photoaging: a systematic review of randomized controlled trials. Int J Womens Dermatol 2022. PMID 35620028. Read 2026-10-31. source
  4. Correia G, Magina S. Efficacy of topical vitamin C in melasma and photoaging: a systematic review. J Cosmet Dermatol 2023. PMID 37128827. Read 2026-10-31. source
  5. Hughes MC et al. Sunscreen and prevention of skin aging: a randomized trial. Ann Intern Med 2013. PMID 23732711. Read 2026-10-31. source
  6. Can dietary intake influence perception of and measured appearance? A systematic review. Nutr Res 2015. PMID 25600848. Read 2026-10-31. source
  7. NHS. Moles. Read 2026-10-31. source
  8. NHS. Symptoms of melanoma skin cancer. Read 2026-10-31. source
  9. NHS. Sunscreen and sun safety. Read 2026-10-31. source
  10. Lau M et al. Cosmeceuticals for antiaging: a systematic review of safety and efficacy. Arch Dermatol Res 2024. PMID 38758222. Read 2026-10-31. source
  11. Natarelli N et al. Oral supplements and photoprotection: a systematic review. J Med Food 2025. PMID 39804624. Read 2026-10-31. source
  12. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. Int J Dermatol 2021. PMID 33742704. Read 2026-10-31. source
  13. Effects of collagen supplements on skin aging: a systematic review and meta-analysis of randomized controlled trials. Am J Med 2025. PMID 40324552. Read 2026-10-31. source

Related on AlternativeMed

Related goals

Protect Your Skin From Sun Damage → Improve Uneven Skin Tone → Improve Skin Texture → Build a Simple Skin-Care Routine → Relieve Dry Skin → Support Your Skin Barrier →

Ingredients, foods and supplements

Vitamin C → Vitamin E → Collagen → Astaxanthin → Coenzyme Q10 → Green tea → Aloe vera →

Research, safety and claim-check resources

Collagen, biotin and beauty supplements → Natural skin-care ingredients → Skin and hair safety → Skin and hair research and evidence → Nutrition for skin and hair → Pregnancy and breastfeeding safety → Supplements for healthy aging →