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Sesame Oil: Nutrients, What Research Shows and Safety

Sesame oil as a food: USDA fat values, sesame allergy and labeling, small trials on blood pressure and blood sugar, medicine cautions and what we could not verify.

Content last updated . This page has not been medically reviewed.

Close-up of sesame oil: nutrients, what research shows and safety

Sesame oil is pressed from the seeds of the sesame plant, Sesamum indicum (family Pedaliaceae). It is a liquid oil used in cooking, dressings and finishing dishes. The USDA item on this page is sesame oil for salad or cooking. [1] Toasted (dark) sesame oil is a different, stronger-flavored product, and we did not find nutrient data for it in the sources we read. Sesame is a major food allergen in the US, so this page spends time on that. It keeps the oil apart from the whole seed and from hype.

Read this first

  • Sesame is a major allergen. Since January 1, 2023, US law lists sesame as the ninth major food allergen. [2] Sesame allergy is increasing and usually lasts. [3] If you are allergic to sesame, ask your allergist before using sesame oil. For trouble breathing or swelling of the face or throat, call 911 (or your local emergency number).
  • Labels: highly refined oils are exempt from major-allergen labeling, and oils that are not highly refined must declare the allergen source. The source must always be in the oil's name. [4] The FDA sesame pages we read did not address oils. [2] [5]
  • It is pure fat and energy dense. USDA lists about 120 kcal in 1 tablespoon (13.6 g). [1]
  • Small trials suggest blood pressure and blood sugar effects, but they are weak. Most were small, open-label, or lacked a control group. [6] [7] [8] If you take medicines for blood pressure or diabetes, tell your clinician before making sesame oil your main oil.
  • Evidence in one line: swapping saturated fat for unsaturated oils lowers LDL cholesterol, [9] but sesame oil has no cholesterol advantage in the trials we read. [6]

What is in it (USDA values)

The values below are for sesame oil, salad or cooking, USDA FoodData Central item 171016, SR Legacy. [1] The serving column is the USDA household portion of 1 tablespoon, 13.6 g. [1]

NutrientPer 100 gPer 1 tbsp (13.6 g)% Daily Value per serving
Energy884 kcal120 kcalnot set
Total fat100 g13.6 g17%
Saturated fat14.2 g1.9 g10%
Monounsaturated fat39.7 g5.4 gno DV
Polyunsaturated fat41.7 g5.7 gno DV
Vitamin E (alpha-tocopherol)1.4 mg0.19 mg1%
Vitamin K13.6 mcg1.8 mcg2%
Phytosterols865 mg118 mgno DV
Cholesterol0 mg0 mg0%
Carbohydrate, protein, fiber0 g0 g0%
Sodium, potassium, phosphorus0 mg0 mg0%

% Daily Value uses the FDA 2016 Daily Values. Serving figures are the 100 g values multiplied by 0.136. USDA lists zero for the last three rows. [1] USDA also lists a vitamin D value for this item, but it looks like a database artifact for a plant oil, so we do not report it. USDA lists no trans fat value for this item.

Sesame oil is low in vitamin E compared with sunflower or safflower oil: USDA lists 1.4 mg per 100 g. [1] Plant compounds: USDA lists plant sterols at 865 mg per 100 g, higher than the other oils in this group that list it. [1] A 2026 review of sesame seeds describes bioactive compounds in the seed, but the compounds in the oil as eaten and their effect in people were not shown in the abstract we read. [10]

What research says

Health goalWhat the sources foundStrength of evidenceWhat was studied
Blood pressureIn 50 people aged 35 to 60 with high blood pressure who took diuretics or beta-blockers, using sesame oil as the only edible oil for 45 days brought blood pressure down to normal, and it rose again when sesame oil was stopped. The abstract describes no separate control group. [6]Promising but limited (small, no control group described)Sesame oil as the only cooking oil, people on blood pressure medicines
Blood vessel functionIn 30 men with high blood pressure, 35 g a day of sesame oil for 2 months improved flow-mediated dilation (a test of artery widening) and lowered one adhesion marker, while a control oil did not. [8]Promising but limited (small, markers)Sesame oil vs a control oil, men with hypertension
Blood sugar in type 2 diabetesIn an open-label study of 60 people, about 35 g a day of sesame oil plus the diabetes drug glibenclamide lowered blood glucose more than either alone (a 36% fall with the combination). [7]Promising but limited (open label, no blinding, short)Sesame oil with a diabetes medicine
CholesterolIn the 45-day blood pressure study, lipids did not change significantly except triglycerides. [6]Insufficient evidenceSesame oil as only edible oil
Overview of oilsAn umbrella review of 48 studies found that sesame oil, olive oil and coconut oil might improve blood sugar control (very low certainty), and that canola and sesame oil might reduce body weight (moderate to very low certainty). [11]Insufficient evidence (very low certainty)Systematic reviews of vegetable oils
LDL cholesterol (replacing saturated fat)The American Heart Association advisory said replacing saturated fat with unsaturated fats lowers LDL. [9] Sesame oil is about 14% saturated fat by USDA. [1]Established for the swap in generalMixed vegetable oils

Eaten as food vs other forms. The trials above used sesame oil as a cooking or salad oil, about 35 g a day, which is more than 2 tablespoons. That is a trial amount, not advice. [8] [7] We did not read trials of sesame oil capsules or sesame lignan supplements.

How much is a normal serving

The USDA household portion is 1 tablespoon (13.6 g), with about 120 kcal. [1] That is information from USDA data, not a prescription. The 2025-2030 Dietary Guidelines say saturated fat should in general stay under 10% of daily calories and name olive oil, butter and beef tallow as cooking fat options; sesame oil is not named in the pages we read. [12] The NHS says men should have no more than 30 g and women no more than 20 g of saturated fat a day. [13] USDA lists 1.9 g saturated fat in a tablespoon of sesame oil. [1]

Safety, allergy and medicines

  • Sesame allergy: sesame is a major US allergen since 2023. [2] Sesame allergy has risen worldwide and typically persists; diagnosis uses a careful history and an oral food challenge. [3] A 2026 review puts IgE-mediated reactions at about 0.1-0.2% of the population. [10] The FDA says to check labels every time because ingredients can change. [5] We did not find a source we could read that says how much sesame protein remains in sesame oil, or whether refined sesame oil triggers reactions. Ask your allergist.
  • Emergency: trouble breathing or swelling of the face or throat after eating is an emergency. Call 911 (or your local emergency number).
  • Blood pressure medicines: in the sesame oil blood pressure study, people were on diuretics or beta-blockers and their pressure fell further to normal. [6] If you take blood pressure medicines, mention a big change in your cooking oil to your clinician.
  • Diabetes medicines: in an open-label study, sesame oil plus glibenclamide lowered glucose more than either alone. [7] That could matter for low blood sugar; ask your care team. This is one small study.
  • Heating and frying: we did not read a study of heated sesame oil. Proper evidence not found in the sources we read.
  • Vitamin K: USDA lists 13.6 mcg per 100 g, about 1.9 mcg a tablespoon (2% of the Daily Value), small compared with soybean oil. [1]
  • Pregnancy, children, kidney disease: we did not find official advice restricting culinary sesame oil in these groups apart from allergy. USDA lists zero potassium, phosphorus and sodium. [1] See foods in pregnancy, food allergy basics and kidney disease and foods.

Choosing, storing and food safety

  • If you must avoid sesame, read every label, and remember a "toasted", "cold-pressed" or "unrefined" oil may not be highly refined. [4]
  • Sesame can be hidden in spice mixes; the FDA guidance says sesame must be declared in a "Contains" statement or in parentheses after "spice". [4]
  • We did not read a source on storage or smoke point for sesame oil. See smoke points and cooking with oil.

Related pages

Oil or fatSesamum indicum (oil)

Health connections for Sesame Oil

What research links to eating or drinking this food, and how strong the evidence is. Many studies are observational or use juice, powder, oil or extracts rather than the food as eaten; each card says which.

Sesame oil and blood pressure

Preliminary or mixed

In 50 people with high blood pressure on diuretics or beta-blockers, sesame oil as the only cooking oil for 45 days lowered blood pressure to normal, and it rose when stopped. No separate control group was described.

Supplements: Cooking oil at trial amounts.

Sesame oil and blood vessel function

Preliminary or mixed

In 30 men with hypertension, 35 g a day of sesame oil improved flow-mediated dilation and lowered one adhesion marker compared with a control oil.

Supplements: Cooking oil at trial amounts.

Sesame oil and blood sugar with diabetes medicine

Preliminary or mixed

In an open-label study of 60 people with type 2 diabetes, sesame oil plus glibenclamide lowered glucose more than either alone.

Supplements: Cooking oil at about 35 g a day.

Sesame oil in reviews of vegetable oils

Preliminary or mixed

An umbrella review found very low certainty evidence that sesame oil improves blood sugar control and moderate to very low certainty that it reduces body weight.

Supplements: Systematic reviews.

Sesame oil in place of saturated fat and LDL cholesterol

Preliminary or mixed

Replacing saturated fat with unsaturated fat lowers LDL. Sesame oil is about 14% saturated; in one trial lipids did not change except triglycerides.

Supplements: Food-oil swap.

Plant sterols and vitamin K in sesame oil

Established role

USDA lists 865 mg plant sterols per 100 g and a small amount of vitamin K (about 1.9 mcg a tablespoon).

Supplements: Dietary role only.

Calories and energy density

Established role

One tablespoon has about 120 kcal and no carbohydrate, protein or fiber.

Supplements: Not applicable.

Connected topics

Open a group to see how each topic connects and how strong the evidence is.

Health goals (2)
  • Blood Pressure SupportPreliminary or mixed

    Small studies in people with hypertension found lower blood pressure or better artery function with about 35 g a day; not enough to recommend.

  • Blood Sugar BalancePreliminary or mixed

    An open-label study found stronger glucose lowering when sesame oil was added to a diabetes medicine; an umbrella review rated the evidence very low.

Body systems (4)
  • Immune SystemDocumented risk

    Sesame is a major food allergen; the sources read did not say whether refined sesame oil triggers reactions.

  • Blood Sugar SupportPreliminary or mixed

    One open-label study with glibenclamide; review certainty very low.

  • Cardiovascular SystemPreliminary or mixed

    Same evidence as heart and circulation.

  • Heart & CirculationPreliminary or mixed

    Small trials found lower blood pressure and better endothelial function in hypertensive people.

Body parts (2)
  • Immune SystemDocumented risk

    Sesame allergy is rising and usually persists.

  • Blood VesselsPreliminary or mixed

    Flow-mediated dilation improved in 30 hypertensive men after 2 months.

Habits (1)
  • Balanced NutritionPreliminary or mixed

    Fits advice to swap saturated for unsaturated fat; a calorie-dense food.

Conditions & symptoms (3)
  • Food AllergyDocumented risk

    Sesame is a major US allergen; whether refined sesame oil triggers reactions was not shown in the sources read.

  • Essential HypertensionPreliminary or mixed

    Small studies in people with hypertension found lower blood pressure or better artery function with sesame oil as the main oil; the first had no control group described.

  • An open-label study found stronger glucose lowering when sesame oil was combined with glibenclamide; reviews rate the evidence very low.

Documented risks and interactions (2)
  • Sesame oil and sesame allergy. Sesame is the ninth major US allergen since 2023. Highly refined oils are exempt from major-allergen labeling but oils that are not highly refined must declare sesame. We found no source on whether refined sesame oil triggers reactions.
  • Sesame oil and medicines. Sesame oil was tested in people already on blood pressure medicines (further drop) and with glibenclamide (stronger glucose lowering). Mention big changes in your cooking oil to your clinician.

Explore all 24 oils and fats

Frequently asked questions

Can sesame oil lower blood pressure?

In a 45-day study of 50 people with high blood pressure on medicines, using sesame oil as the only cooking oil brought pressure down, with no separate control group described. [6] A second small trial found better artery function. [8] This is promising but not strong enough to recommend it as a treatment.

Is sesame oil safe with diabetes medicines?

In an open-label study of 60 people, sesame oil plus glibenclamide lowered glucose more than either alone. [7] Tell your care team before changing your oil, in case your medicine needs adjusting.

Is sesame oil an allergen?

Sesame is a major US food allergen, [2] and the oil comes from sesame seeds. Highly refined oils are exempt from major-allergen labeling, but oils that are not highly refined must declare sesame. [4] If you are allergic, ask your allergist.

Is toasted sesame oil the same as sesame oil?

Not exactly. The USDA data on this page are for sesame oil for salad or cooking. [1] We did not find nutrient data for toasted sesame oil in the sources we read.

Does sesame oil lower cholesterol?

Not in the trials we read: lipids did not change except triglycerides in one study. [6] Replacing saturated fat with unsaturated fat lowers LDL in general. [9]

References
  1. U.S. Department of Agriculture. FoodData Central: Oil, sesame, salad or cooking (SR Legacy, FDC 171016). 2018. Read 2026-10-24.
  2. U.S. Food and Drug Administration. The FASTER Act: Sesame Is the Ninth Major Food Allergen. Read 2026-10-24.
  3. J Food Allergy (Kaman K, Factor JM). A practical focus on sesame allergy and a brief review of other seed allergies. 2022 (abstract read via Europe PMC). Read 2026-10-24.
  4. U.S. Food and Drug Administration. Questions and Answers Regarding Food Allergens, including the Food Allergen Labeling Requirements (guidance for industry, question D.9 on labeling oils). Edition 5, January 2025. Read 2026-10-24.
  5. U.S. Food and Drug Administration. An Update on Sesame Allergen Labeling on Food Packages (FDA Voices). 2023. Read 2026-10-24.
  6. Yale J Biol Med (Sankar D et al.). Effect of sesame oil on diuretics or Beta-blockers in the modulation of blood pressure, anthropometry, lipid profile, and redox status. 2006 (abstract read via Europe PMC). Read 2026-10-24.
  7. Clinical Nutrition (Sankar D et al.). Sesame oil exhibits synergistic effect with anti-diabetic medication in patients with type 2 diabetes mellitus. 2011 (abstract read via Europe PMC). Read 2026-10-24.
  8. Eur J Prev Cardiol (Karatzi K et al.). Sesame oil consumption exerts a beneficial effect on endothelial function in hypertensive men. 2013 (abstract read via Europe PMC). Read 2026-10-24.
  9. American Heart Association (Sacks FM et al.). Dietary Fats and Cardiovascular Disease: A Presidential Advisory. 2017 (abstract read via Europe PMC). Read 2026-10-24.
  10. Food Chemistry (Zhao J et al.). A systematic review on the nutrition, health benefits, and allergy risks of sesame seeds. 2026 (abstract read via Europe PMC). Read 2026-10-24.
  11. Advances in Nutrition (Voon PT et al.). Health Effects of Various Edible Vegetable Oil: An Umbrella Review. 2024 (abstract read via Europe PMC). Read 2026-10-24.
  12. U.S. Department of Health and Human Services and USDA. Dietary Guidelines for Americans 2025-2030 (consumer summary pages). 2025-2030 edition. Read 2026-10-24.
  13. NHS. Fat: the facts (different fats in our diet). Read 2026-10-24.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.