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Violet-toothed polypore, a thin purple-edged bracket fungus on dead hardwood
Violet-toothed polypore grows on dead hardwood. We could not confirm any use as medicine in people.

Mushrooms · Wild polypore

Violet-toothed polypore

Trichaptum biforme (Pallidohirschioporus biformis) · also called Violet-pored bracket fungus, purple tooth

Violet-toothed polypore is a leathery, purple-edged bracket fungus that rots dead hardwood. We found no source describing it as a food and no supplement made from it. The research is a handful of laboratory studies and none in people, and turkey tail results do not apply to it. Do not use a wild fungus unless an expert has identified it.

General information, not medical advice. Last substantive update · Not medically reviewed. A named clinician has not signed off on this page. How this page is made

About Violet-toothed polypore

Violet-toothed polypore is a leathery, purple-edged bracket fungus that grows on dead hardwood. Human research does not exist. The little that is known comes from test-tube and cell-dish work on extracts and isolated molecules. We found no safety data, no identification guide and no product. Do not use a wild fungus without an expert.

What it is, and the naming

It is a white-rot, wood-decay fungus in the order Hymenochaetales. A 2026 paper calls it a common annual polypore of subtropical to temperate parts of the Northern Hemisphere. Wikipedia says it grows to 1 to 7.5 cm across, starts violet, and fades to white and brown with a violet margin for a time.

The scientific name is in flux. GBIF lists Trichaptum biforme as accepted, while recent papers call it Pallidohirschioporus biformis. Its genome was sequenced in 2025 and its mitochondrial genome in 2026, to study how it breaks down wood.

It is not turkey tail. Turkey tail research (PSK, PSP, trials in cancer care) concerns Trametes versicolor and does not transfer to this fungus.

1 10 8 11 9

What the research shows

Nothing has been tested in people. In a 2024 cell-dish study, a hot-water polysaccharide extract (78.18% polysaccharide by a sugar assay) raised IL-1 beta and TNF-alpha release from a human monocyte cell line and, with IL-2, increased natural killer cell activity.

In a 2026 test-tube study of wild fruiting bodies, extracts blocked hyaluronidase and butyrylcholinesterase but not acetylcholinesterase, and showed no antibacterial effect on seven bacteria. Compounds from lab cultures had negligible or weak effect on cancer cell lines, and a 2018 Russian screen did not list this fungus among the active ones.

These results show interesting chemistry. They cannot show a health effect, because test-tube and cell results often fail in people.

2 8 12 7

How strong is the evidence?

Every result is rated not enough evidence. It is laboratory work, mostly read from abstracts, on different material (an extract, wild fruiting bodies, lab cultures and mycelium). Much of the chemistry comes from lab cultures rather than the wild fruiting body, and the two can differ. One 1947 paper was read by title only.

2 8 12 6

Forms and products

We found no consumer product made from this fungus, so we cannot say what one would contain. The lab work used extracts and isolated molecules, which are not tea, powder or capsules. For medicinal mushrooms in general, the US National Cancer Institute says supplement ingredients may vary considerably from lot to lot. If a turkey tail product lists Trichaptum instead of Trametes versicolor, ask the seller for a certificate of analysis.

5 2

Rules and regulators

The US National Cancer Institute says the FDA has not approved medicinal mushrooms as a treatment for cancer or any other medical condition. Its page has no section on this fungus. We found no entry in LiverTox or LactMed, and we did not check EMA, NCCIH or MSK.

5 4

At a glance

Traditional uses history, not proof

  • No traditional medicinal or food use of violet-toothed polypore was found in the sources we read.

Studied for research

  • Immune-cell tests, not enough evidence (cell dish only)
  • Cancer cell-line tests, not enough evidence (mostly no effect)
  • Enzyme and antioxidant tests, not enough evidence (test tube only)
  • Germ-killing tests, not enough evidence (mixed lab results)
  • Any use in people, not enough evidence (nothing found)

Main compounds

  • Hot-water polysaccharides (long sugar chains)
  • Sterols such as ergosterol peroxide
  • Butenolides and betulin

Common forms

  • Hot-water and solvent extracts (laboratory only)
  • No consumer product was found

Research links: Phytochemical analysis and immune-modulatory potential of Trichaptum biforme polysaccharides (abstract) · Butenolides and triterpenoids from Pallidohirschioporus biformis (abstract) · Two new drimane sesquiterpenoids from Trichaptum biforme cultures (open access) · Antiproliferative activity of wood-destroying mushrooms from Russia (abstract) · NCI: Medicinal mushrooms (PDQ) · Research Library · Genes & Biomarkers Library

What it is and its history

Accepted scientific name
Trichaptum biforme
Naming authority
(Fr.) Ryvarden (GBIF)
Synonyms
Pallidohirschioporus biformis (the newer name used in 2025 and 2026 papers); Polyporus biformis (old name used in the 1947 paper)
Common names
Violet-toothed polypore (English); Violet-pored bracket fungus (English); Purple tooth (English)
Family or group
A fungus family, not a plant
Classification
Fungi > Basidiomycota > Agaricomycetes > Hymenochaetales > Trichaptaceae (per the 2026 mitochondrial genome paper title; GBIF returned no family) > Trichaptum (the 2026 paper uses Pallidohirschioporus) > Trichaptum biforme
Native range
Subtropical to temperate Northern Hemisphere (2026 paper); described as widely distributed (Wikipedia).
Habitat
White-rot wood-decay fungus on dead hardwood stumps and logs; recorded on at least 65 tree hosts and rarely on conifers (Wikipedia).
What it looks like
Fruiting body: Annual bracket 1 to 7.5 cm across; violet when young, fading to white and brown zones with violet kept at the margin for a time (Wikipedia). No other description was read from a source.
Cultivation
Not found in the sources read.
Harvest and processing
Not found in the sources read.
Look-alikes and adulterants
Name: Trichaptum abietinum, T. byssogenum, T. fuscoviolaceum, Skeletocutis lilacina; Note: Listed by Wikipedia as sometimes confused with this fungus; the first three grow mainly on conifers.; Name: Turkey tail (Trametes versicolor); Note: Sometimes compared because of a similar look; a different fungus with different chemistry and research.

Traditional use and history history, not clinical proof

Tradition or eraDocumented useSource
Traditional useNo traditional medicinal or food use was found in the sources read.p42358799
1947 laboratory screeningCultures (as Polyporus biformis) were screened for antibiotic substances; the 2026 paper says biformin was first reported then.p16588738

Traditional use shows how it was used. It does not show that it works or is safe today.

What is inside, and how it may work

What it contains and how those compounds act in cells and animals. Laboratory and animal mechanisms are not proven effects in people.

Main compounds

CompoundFamilyWhere it is concentratedActivity studiedLevel of evidence
Hot-water polysaccharides (TBP)polysaccharideFruiting bodies, hot-water extract
78.18 +/- 0.81 % of the purified extract by phenol-sulfuric assay; this describes the extract, not the mushroom.
Raised IL-1 beta, TNF-alpha, and (with IL-2) NK-cell activity in cell culture. 2Laboratory research
Ergosterol peroxide, its glucoside, and 9,11-dehydroergosterol peroxidesterolFruiting bodies
Not given in the abstracts.
The glucoside gave 91% hyaluronidase inhibition in a test tube. 8 2Laboratory research
BetulintriterpeneFruiting bodies, methanol extract
Not given in the abstract.
Moderate hyaluronidase inhibition (32%) in a test tube. 8Laboratory research
Butenolides: biformolide (new), hydroxydihydrobovolide, schumannione, and a methoxy-furanone nonanoic acidbutenolideFruiting bodies, methanol extract
Not given in the abstract.
Hydroxydihydrobovolide was the main butyrylcholinesterase blocker in a test tube. 8Laboratory research
Drimane sesquiterpenoids (two new)sesquiterpenoidLaboratory cultures
Not given in the abstract.
Negligible cytotoxicity against five human cancer cell lines. 12Laboratory research
BiforminpolyacetyleneLaboratory cultures
Not stated.
Reported antibacterial in 1947, as cited by the 2026 paper; not re-read. 6 8Lab analysis

Mechanisms, receptors and pathways

Target or pathwayGene or receptorWhat was foundLevel
Immune messengers and natural killer cellsIL-1 beta, TNF-alpha, IFN-gammaA hot-water polysaccharide extract raised release of these messengers in cell culture. The route was not shown in the abstract. 2Laboratory research
HyaluronidaseExtracts and ergosterol peroxide glucoside inhibited the enzyme in a test tube. 8Laboratory research
ButyrylcholinesteraseMethanol and chloroform extracts inhibited it; acetylcholinesterase was not inhibited. 8Laboratory research

Absorption, metabolism and elimination

Absorption
Not found in the sources read.
Distribution
Not found in the sources read.
Metabolism
Not found in the sources read.
Elimination
Not found in the sources read.
Bioavailability
Not established.

Isolated compounds versus whole extracts

The activity data are for a purified hot-water polysaccharide extract, for solvent extracts and isolated molecules, and for mycelium extracts. None is a tea, powder or capsule, and no product comparison exists.

Nutritional composition

No food-composition data were found for this fungus. It is a leathery wood-decay bracket and we make no nutrition claim.

6benefits and uses looked at
12studies and sources checked
Not enough evidencebest evidence rating found
6lab markers tracked in trials

6 not enough evidence

What was looked at

The 6 benefits and uses checked for Violet-toothed polypore, each with how strong the evidence is. Tap one to open it.

Lab markers tracked in the studies

IL-1 beta and TNF-alpha release from THP-1 cellsNatural killer cell activity and IFN-gamma releaseGrowth of human cancer cell lines in a dishHyaluronidase inhibition in a test tubeAcetylcholinesterase and butyrylcholinesterase inhibitionBacterial growth (MIC) in a test tube

What is Violet-toothed polypore good for?

The uses people ask about and how strong the human evidence is for each. None is shown in people. Read this together with the Safety tab.

Benefits, one by one

Each card is a research question, not a promise. Tap a goal to filter. Open a card to see the studies, doses and limits.

Immune-cell tests (cell dish only)

Not enough evidence

A hot-water extract of the fungus made human immune-type cells in a dish release more inflammatory messengers, and boosted natural killer cell activity when IL-2 was added. Nothing was tested in animals or people, so this does not show an immune benefit.

1 studiesHot-water polysaccharide extract made in a laboratory. This is not a …

Studies, doses and limits

Results

In one 2024 study, a purified hot-water polysaccharide extract (78.18% polysaccharide by a sugar assay) significantly raised IL-1 beta and TNF-alpha release from a human monocyte cell line (THP-1) at 10 and 320 ug/mL (p < 0.01). Natural killer cells treated with the extract (320 ug/mL) plus IL-2 showed significantly more killing activity and IFN-gamma release than the control (p < 0.01).

Effect sizes as reported

Significant changes in cell culture; no size of effect given in the abstract

Why this rating

One abstract-only laboratory paper on one extract. Cell results often fail in animals and people. Raising inflammatory messengers is not automatically good.

Form and dose studied

Hot-water polysaccharide extract made in a laboratory. This is not a tea, powder or capsule, and no such product was found.

Who was studied

Human cell lines and cells in culture

Limits

Single paper; abstract only; repeats not stated; extract concentrations are lab concentrations, not doses.

Why researchers looked

Researchers screen fungal polysaccharides (long sugar chains) for immune effects because some other mushrooms have them.

Traditional use

No traditional medicinal or food use of violet-toothed polypore was found in the sources we read.

Proposed mechanism Laboratory research

The paper measured messenger release (IL-1 beta, TNF-alpha, IFN-gamma) and killing activity of natural killer cells in cell culture. How the extract acts on the cells was not shown in the abstract.

A proposed mechanism does not show that the effect happens in people.

No human safety data were found. See the Safety tab. Do not use a wild fungus unless an expert has identified it.

2

Cancer cell-line tests (mostly no effect)

Not enough evidence

Compounds grown in lab cultures of the fungus had negligible or weak effect on human cancer cells in a dish, and a screen of six wood-decay fungi did not list this one among the active ones. This does not show any anticancer use.

3 studiesCompounds isolated from lab cultures and mycelium extracts; none is a…

Studies, doses and limits

Results

Two new drimane sesquiterpenoids from cultures had negligible cytotoxicity against five human cancer cell lines (2013). The 2026 paper says earlier cadinane sesquiterpenes and 13-carbon lactones from cultures had no significant activity, and one (trichapargin A) was weakly active on one cell line. In a 2018 Russian screen of six wood-decay fungi, five species (not this one) were reported to have cytotoxic or growth-inhibiting effects; the abstract gives no separate result for this fungus.

Effect sizes as reported

No meaningful activity reported

Why this rating

Lab-only and mostly null. The 2018 result for this species is inferred from its absence in the list of active species.

Form and dose studied

Compounds isolated from lab cultures and mycelium extracts; none is a product.

Who was studied

Human cancer cell lines in culture

Limits

Cultures may differ from the wild fruiting body. The 2024 immune paper frames its work as relevant to cancer, but it did not test killing of cancer cells directly in the abstract.

Why researchers looked

Natural product chemists test new compounds on cancer cell lines as a routine first screen.

Traditional use

No traditional medicinal or food use of violet-toothed polypore was found in the sources we read.

Proposed mechanism Laboratory research

Not applicable: the tests found little or no activity.

A proposed mechanism does not show that the effect happens in people.

No human safety data were found. See the Safety tab. Do not use a wild fungus unless an expert has identified it.

7 12 8

Any use in people

Not enough evidence

We found no human trial, case report, animal study of a health outcome, or safety study of violet-toothed polypore. For every health claim the honest answer is: not enough evidence. Turkey tail findings do not carry over to it.

2 studiesNo consumer product was found.

Studies, doses and limits

Results

No human results to report.

Why this rating

No human study exists in the sources we searched.

Form and dose studied

No consumer product was found.

Limits

Absence of evidence is not evidence of safety or of benefit.

Why researchers looked

Readers ask whether it is a medicinal mushroom like turkey tail because it looks similar. For this fungus the research is not there.

Traditional use

No traditional medicinal or food use of violet-toothed polypore was found in the sources we read.

Proposed mechanism None

Not applicable.

A proposed mechanism does not show that the effect happens in people.

No human safety data were found. See the Safety tab. Do not use a wild fungus unless an expert has identified it.

8 2

Enzyme and antioxidant tests of extracts (test tube only)

Not enough evidence

Extracts of wild fruiting bodies blocked the enzyme hyaluronidase in a test tube, and blocked butyrylcholinesterase but not acetylcholinesterase. These are chemistry results, not effects on skin, memory or any condition.

1 studiesSolvent extracts and isolated molecules, not a food or supplement.

Studies, doses and limits

Results

Wild fruiting body extracts (methanol, chloroform, n-hexane) were tested in 2026. Hyaluronidase looked like the main target: the chloroform extract gave 47% inhibition at 5 mg/mL, and the chloroform and methanol extracts 79 to 97% at 10 and 20 mg/mL. The methanol and chloroform extracts blocked butyrylcholinesterase (about 51% at 40 mg/mL) but showed no acetylcholinesterase inhibition. The alpha-glucosidase and tyrosinase tests and an antioxidant (ABTS) test were also run; the abstract gives no numbers for them. A figure caption says methanol and chloroform extracts generally did better than hexane in the antioxidant test, below the vitamin C reference.

Effect sizes as reported

Test-tube percentages; the concentrations are very high and are not doses

Why this rating

Single laboratory paper on one batch of wild fungus; the enzyme results do not show any effect in a body.

Form and dose studied

Solvent extracts and isolated molecules, not a food or supplement.

Who was studied

Enzymes in a test tube

Limits

One paper; some numbers come from the full text and from figure captions; bar-chart values were not extracted; the authors say comparisons with other species are limited.

Why researchers looked

Researchers run enzyme tests on many fungi to find which ones have interesting chemistry. Hyaluronidase breaks down hyaluronic acid; butyrylcholinesterase is a brain-related enzyme.

Traditional use

No traditional medicinal or food use of violet-toothed polypore was found in the sources we read.

Proposed mechanism Laboratory research

Pure compounds in the extract were the active part: ergosterol peroxide glucoside (91% hyaluronidase inhibition), betulin (32%) and hydroxydihydrobovolide (the main butyrylcholinesterase blocker).

A proposed mechanism does not show that the effect happens in people.

No human safety data were found. See the Safety tab. Do not use a wild fungus unless an expert has identified it.

8

Germ-killing tests (mixed lab results)

Not enough evidence

A 1947 culture study is said to have found an antibacterial compound called biformin, but a 2026 test of extracts from wild fruiting bodies found no antibacterial effect on seven bacteria. Neither shows that it treats any infection.

2 studiesLaboratory culture compound; solvent extracts. No product.

Studies, doses and limits

Results

The 2026 paper reports that the fungal extracts did not show antibacterial properties against seven bacterial strains (MIC above 400 ug/mL). It also says Robbins and colleagues first reported biformin from cultures in 1947 with antibacterial activity; we could read only the 1947 paper's title, not its content.

Effect sizes as reported

No antibacterial effect from the 2026 extracts; the 1947 effect is unquantified here

Why this rating

The two reports disagree, use different material (culture versus wild fruiting body extract), and one was only read second-hand.

Form and dose studied

Laboratory culture compound; solvent extracts. No product.

Who was studied

Bacteria in test tubes

Limits

The 1947 abstract is not available. Different material in each paper.

Why researchers looked

Antibiotic discovery programmes screened many fungi in the 1940s, and chemists still run antibacterial tests today.

Traditional use

No traditional medicinal or food use of violet-toothed polypore was found in the sources we read.

Proposed mechanism Laboratory research

Biformin is a polyacetylene (a chain-like molecule) said to come from cultures of the fungus.

A proposed mechanism does not show that the effect happens in people.

No human safety data were found. See the Safety tab. Do not use a wild fungus unless an expert has identified it.

8 6

As a food (nutrition)

Not enough evidence

We found no source that describes violet-toothed polypore as a food and no nutrient data. A general encyclopedia calls it inedible. It is a leathery wood-decay bracket.

2 studiesNot a food product.

Studies, doses and limits

Results

No food-composition data were found. Element content of wild fruiting bodies was measured in a 2021 Turkish study that included this species, but the abstract gives only ranges across all 20 species, not a value for this one.

Why this rating

No nutrient or food-safety data for this species in the sources we read.

Form and dose studied

Not a food product.

Limits

Wikipedia's 'inedible' is a general-source statement, not a toxicology finding.

Why researchers looked

Readers ask whether it can be eaten like a mushroom.

Traditional use

No traditional medicinal or food use of violet-toothed polypore was found in the sources we read.

Proposed mechanism None

Not applicable.

A proposed mechanism does not show that the effect happens in people.

No human safety data were found. See the Safety tab. Do not use a wild fungus unless an expert has identified it.

3 10

Connections to the rest of health

How Violet-toothed polypore connects to the rest of our health knowledge graph. Every link says what kind of connection it is. A safety link (for example to the liver) is a warning, not a benefit. A study that merely mentions a topic never creates a benefit link.

Explore every connection: goals, body systems, organs, symptoms, genes

A. Wellness goals

Connected toKind of connectionEvidence statusContextStudies
Immune Health Preliminary mechanism Not enough evidence Immune-cell tests (cell dish only): A hot-water extract of the fungus made human immune-type cells in a dish release more inflammatory messengers, and boosted natural killer cell activity when IL-2 was added. Nothing was tested in animals or people, so this does not show an immune benefit. Germ-killing tests (mixed lab results): A 1947 culture study is said to have found an antibacterial compound called biformin, but a 2026 test of extracts from wild fruiting bodies found no antibacterial effect on seven bacteria. Neither shows that it treats any infection. 2 8 6
Cancer Support Not enough evidence Cancer cell-line tests (mostly no effect): Compounds grown in lab cultures of the fungus had negligible or weak effect on human cancer cells in a dish, and a screen of six wood-decay fungi did not list this one among the active ones. This does not show any anticancer use. 7 12 8
Healthy Aging Preliminary mechanism Not enough evidence Enzyme and antioxidant tests of extracts (test tube only): Extracts of wild fruiting bodies blocked the enzyme hyaluronidase in a test tube, and blocked butyrylcholinesterase but not acetylcholinesterase. These are chemistry results, not effects on skin, memory or any condition. 8
Nutrition Not enough evidence As a food (nutrition): We found no source that describes violet-toothed polypore as a food and no nutrient data. A general encyclopedia calls it inedible. It is a leathery wood-decay bracket. 3 10

B. Body systems

Connected toKind of connectionEvidence statusContextStudies
Immune System Biological association Not enough evidence Studied for: Immune-cell tests (cell dish only) Studied for: Cancer cell-line tests (mostly no effect) 2 7 12 8 6
Cellular Protection Biological association Not enough evidence Studied for: Enzyme and antioxidant tests of extracts (test tube only) 8
Digestive System Biological association Not enough evidence Studied for: As a food (nutrition) 3 10

E. Health conditions

Connected toKind of connectionEvidence statusContextStudies
Pregnancy and breastfeeding Contraindication Not enough evidence No safety data found.
Preparation or compound: All violet-toothed polypore products
4

I. Biomarkers

Connected toKind of connectionEvidence statusContextStudies
IL-1 beta and TNF-alpha release from THP-1 cells Biological association Not enough evidence Measured in trials: increased. A lab change is not the same as a health benefit. 2
Natural killer cell activity and IFN-gamma release Biological association Not enough evidence Measured in trials: increased. A lab change is not the same as a health benefit. 2
Growth of human cancer cell lines in a dish Biological association Not enough evidence Measured in trials: no change. A lab change is not the same as a health benefit. 12 7
Hyaluronidase inhibition in a test tube Biological association Not enough evidence Measured in trials: inhibited. A lab change is not the same as a health benefit. 8
Acetylcholinesterase and butyrylcholinesterase inhibition Biological association Not enough evidence Measured in trials: mixed. A lab change is not the same as a health benefit. 8
Bacterial growth (MIC) in a test tube Biological association Not enough evidence Measured in trials: no change. A lab change is not the same as a health benefit. 8

L. Active compounds

Connected toKind of connectionEvidence statusContextStudies
Hot-water polysaccharides (TBP) Biological association In vitro Raised IL-1 beta, TNF-alpha, and (with IL-2) NK-cell activity in cell culture.
Preparation or compound: Fruiting bodies, hot-water extract
2
Ergosterol peroxide, its glucoside, and 9,11-dehydroergosterol peroxide Biological association In vitro The glucoside gave 91% hyaluronidase inhibition in a test tube.
Preparation or compound: Fruiting bodies
8 2
Betulin Biological association In vitro Moderate hyaluronidase inhibition (32%) in a test tube.
Preparation or compound: Fruiting bodies, methanol extract
8
Butenolides: biformolide (new), hydroxydihydrobovolide, schumannione, and a methoxy-furanone nonanoic acid Biological association In vitro Hydroxydihydrobovolide was the main butyrylcholinesterase blocker in a test tube.
Preparation or compound: Fruiting bodies, methanol extract
8
Drimane sesquiterpenoids (two new) Biological association In vitro Negligible cytotoxicity against five human cancer cell lines.
Preparation or compound: Laboratory cultures
12
Biformin Biological association Lab analysis Reported antibacterial in 1947, as cited by the 2026 paper; not re-read.
Preparation or compound: Laboratory cultures
6 8

Each connection is stored with the ingredient, the connected record, the kind of connection, the evidence status, the supporting studies, the preparation or compound involved, and a review date (last reviewed October 25, 2026).

Evidence at a glance: what changed in 1 lab markers

Tap a number to show only those markers. Counts are markers, not people.

The evidence

The research centre for Violet-toothed polypore. Every record here was checked against PubMed or the publisher's page; we never list a study we have not verified.

Evidence by outcome

Bars show how many studies we found for each outcome, not how well it works. People are added up across trials only (reviews are not added, to avoid double counting).

How we rate evidence

High certainty

Several well-run trials or reviews agree; further research is unlikely to change the picture much.

Moderate certainty

Good trials point the same way, but some doubt remains.

Low certainty

Small, short or inconsistent trials. The finding could change with better research.

Very low certainty

Very little or very weak human data. Treat as a possibility only.

Mixed findings

Trials or reviews disagree with each other.

Not enough evidence

Not enough human research to say either way.

Evidence against

Good research found no benefit, or found harm.

We take the reviewers' own risk-of-bias and GRADE statements where they exist, and otherwise judge from study size, design, consistency, directness and whether a product matches what is sold. Many publications do not make evidence high. Method note: We read PubMed records and abstracts for 7 papers on this fungus (immune cells, enzymes, cancer cell lines, chemistry, two genome papers) plus a 1947 record by title, parts of the open-access 2026 full text, the open-access 2013 chemistry abstract and a 2021 element study that included the species. We checked the name in GBIF, read a Wikipedia extract for description and look-alikes, read the National Cancer Institute medicinal mushrooms page, and searched NCBI Books for LiverTox and LactMed entries. Certainty ratings are the compiler's own reading.

Study library: every study we checked 12
StudyDesignPeopleProduct, dose, lengthResult
GBIF 2026
GBIF Backbone Taxonomy: Trichaptum biforme
GBIF · Source
Database record
n/a
n/a n/a
On 2026-10-25 the GBIF match API gave Trichaptum biforme (Fr.) Ryvarden as ACCEPTED (key 5247228), kingdom Fungi, phylum Basidiomycota, class Agaricomycetes, order Hymenochaetales. The match returned no family. A search for Pallidohirschioporus biformis matched only the kingdom, so GBIF did not recognise the newer name on that date.
Name check
Methods, limits and funding

Outcomes: Name check

Limitations: Index Fungorum was not checked, so the newer name could not be confirmed there.

Funding and conflicts: Not applicable

Read: database record

Habibi 2024
Phytochemical analysis and immune-modulatory potential of Trichaptum biforme polysaccharides: Implications for cancer.
International Journal of Biological Macromolecules · PMID 39284468 · DOI
Laboratory study
Trichaptum biforme
Cell cultures: a human monocyte cell line (THP-1) and natural killer (NK) cells; chemical assays Hot-water polysaccharide extract (TBP) from the fungus; three sterol derivatives from the n-hexane fraction
Fruiting bodies (the abstract says "T. biforme"; the part is not spelled out)
TBP made up 78.18 +/- 0.81 % of the purified hot-water extract by the phenol-sulfuric acid assay (an extract purity figure, not a content value for the mushroom). In THP-1 cells it significantly raised IL-1 beta and TNF-alpha release at 10 and 320 ug/mL (p < 0.01). NK cells treated with the extract (320 ug/mL) plus IL-2 showed significantly higher cytotoxic activity and IFN-gamma release than the control (p < 0.01). A sterol, 9,11-dehydroergosterol peroxide, was identified in this fungus for the first time. The abstract says antioxidant activity was assessed (DPPH and FRAP) but gives no result.
Immune messenger release and NK-cell activity in cell culture; chemistry of the extract
Methods, limits and funding

Outcomes: Immune messenger release and NK-cell activity in cell culture; chemistry of the extract

Limitations: Cell-dish work only. Abstract read, not the full text. Number of repeats is not given in the abstract. IL-1 beta and TNF-alpha are inflammatory messengers, so a rise is not automatically a benefit. The authors' conclusion that it is a candidate for "bolstering anticancer immune responses" goes beyond a cell-culture result.

Funding and conflicts: The authors declare no competing financial interests (abstract).

Read: abstract

Keskin 2021
Element concentration, daily intake of elements, and health risk indices of wild mushrooms collected from Belgrad Forest and Ilgaz Mountain National Park (Turkey).
Environmental Science and Pollution Research · PMID 33982259 · DOI
Chemical analysis
20 wild mushroom species incl. Trichaptum biforme
Wild mushrooms from two Turkish forests; 20 species including Trichaptum biforme Wild fruiting bodies, element analysis
Fruiting bodies
The abstract gives element ranges across all 20 species together (for example mercury 14.03 to 37.81 and cadmium 0.09 to 2.4 mg/kg dry weight) and does not give a value for T. biforme. Intake and risk indices were worked out for edible species only, and some of those (not T. biforme) exceeded legal limits. The authors say the species should be eaten in a controlled manner.
Element (metal and mineral) content
Methods, limits and funding

Outcomes: Element (metal and mineral) content

Limitations: No T. biforme value in the abstract. It shows that wild mushrooms in general can contain metals, not what this species contains.

Funding and conflicts: Not stated in the abstract

Read: abstract

NCBI Bookshelf 2026
NCBI Books search for LiverTox and LactMed entries (Trichaptum, Pallidohirschioporus)
NCBI Bookshelf · Source
Database search
n/a
n/a n/a
Searches of NCBI Books on 2026-10-25 for "Trichaptum" and for "Pallidohirschioporus" each returned zero results. No LiverTox or LactMed entry for this fungus was found.
No entry found
Methods, limits and funding

Outcomes: No entry found

Limitations: A search for a name is not a full review. EMA and NCCIH pages were not checked.

Funding and conflicts: Not applicable

Read: search result

National Cancer Institute 2024
NCI PDQ: Medicinal Mushrooms (health professional version)
National Cancer Institute · Source
Authoritative guidance
n/a
n/a n/a
Page text read on 2026-10-25. It says supplement ingredients may vary considerably from lot to lot with no guarantee that label ingredients are present, and that the FDA has not approved medicinal mushrooms as a treatment for cancer or any other medical condition. It has no section on violet-toothed polypore.
General regulatory caution
Methods, limits and funding

Outcomes: General regulatory caution

Limitations: Not about this fungus; applies by analogy only.

Funding and conflicts: Not applicable

Read: page text

Robbins 1947
Antibiotics from Basidiomycetes: II. Polyporus biformis.
Proceedings of the National Academy of Sciences USA · PMID 16588738 · DOI
Laboratory study (historical)
Polyporus biformis (old name for Trichaptum biforme)
Not stated (PubMed record has no abstract) Culture of Polyporus biformis (old name for this fungus)
Laboratory culture
The PubMed record has a title but no abstract. The 2026 paper (Suratno et al.) says this 1947 work first reported biformin, a polyacetylene from cultures with antibacterial activity.
Title only: antibiotic substances from this fungus
Methods, limits and funding

Outcomes: Title only: antibiotic substances from this fungus

Limitations: Only the title was read. The antibacterial claim is as cited by the 2026 paper, not read in the original. A 1947 culture result says nothing about people.

Funding and conflicts: Not stated

Read: title only (PubMed record)

Shnyreva 2018
Antiproliferative Activity and Cytotoxicity of Some Medicinal Wood-Destroying Mushrooms from Russia.
International Journal of Medicinal Mushrooms · PMID 29604909 · DOI
Laboratory study
Trichaptum biforme (mycelium) among six species
Leukemia and solid-tumour cell lines in culture; six wood-decay fungi from Central Russia Hot-water extracts and methanol-chloroform extracts of mycelial biomass
Mycelium grown from wild-collected strains
The authors screened six fungi including Trichaptum biforme. They report cytotoxic and growth-inhibiting effects of hot-water extracts for five species (Trametes versicolor, Coniophora puteana, Fomes fomentarius, Fomitopsis pinicola, Inonotus obliquus). T. biforme is not among the five named. The most effective extract was a methanol extract of T. versicolor. The abstract gives no separate result for T. biforme.
Cell growth inhibition
Methods, limits and funding

Outcomes: Cell growth inhibition

Limitations: Cell-dish work on mycelium, not fruiting bodies. The result for T. biforme is inferred from its absence in the list of active species; the abstract does not state it directly.

Funding and conflicts: Not stated in the abstract

Read: abstract

Suratno 2026
Butenolides and triterpenoids from the fungus Pallidohirschioporus biformis (syn. Trichaptum biforme): isolation, structure determination and bioactivity profile.
Frontiers in Fungal Biology · PMID 42358799 · DOI
Laboratory study (chemistry and enzyme tests)
Pallidohirschioporus biformis (Trichaptum biforme), wild fruiting bodies
Test-tube assays (enzymes, seven bacterial strains, antioxidant test) on extracts and eight isolated compounds Methanol, chloroform and n-hexane extracts of the fungus; eight isolated compounds
Wild-growing fruiting bodies (sporocarps)
Eight compounds were isolated from the methanol extract; biformolide is new and one other butenolide was reported from natural sources for the first time. Hyaluronidase looked like the main enzyme target of the extracts. Ergosterol peroxide glucoside gave 91% hyaluronidase inhibition and betulin 32%; the other compounds had little or none. The methanol and chloroform extracts blocked butyrylcholinesterase (about 51% at 40 mg/mL, from the full text) but showed no inhibition of acetylcholinesterase; hydroxydihydrobovolide was the main active compound. The full text states that the extracts showed no antibacterial effect on seven bacterial strains (MIC above 400 ug/mL). A figure caption says methanol and chloroform extracts generally did better than the hexane extract in the hyaluronidase and antioxidant (ABTS) tests, below the reference standards.
Enzyme-inhibition and antioxidant tests; antibacterial tests; chemistry
Methods, limits and funding

Outcomes: Enzyme-inhibition and antioxidant tests; antibacterial tests; chemistry

Limitations: Test-tube work. Abstract and parts of the open-access full text read (introduction, methods, parts of results); the bar-chart values were not extracted. Concentrations used (mg/mL) are far above anything a person could reach, so these are not doses. The authors say direct comparisons with other species are limited.

Funding and conflicts: The authors declared no commercial or financial relationships (abstract).

Read: abstract and open-access full text (parts)

Wei 2026
The first complete mitochondrial genome of Trichaptum biforme (Fr.) Ryvarden 1972 within the family Trichaptaceae, Hymenochaetales.
Mitochondrial DNA Part B · PMID 42205523 · DOI
Genome sequencing
Trichaptum biforme
One specimen from the Qinling Mountains, Shaanxi, China n/a
The mitochondrial genome is 55,598 base pairs long. The paper places the fungus in the family Trichaptaceae, order Hymenochaetales.
Mitochondrial genome
Methods, limits and funding

Outcomes: Mitochondrial genome

Limitations: Genetics only; nothing on health, food or safety.

Funding and conflicts: No potential conflict of interest reported (abstract).

Read: abstract

Wikipedia 2026
Wikipedia: Trichaptum biforme
Wikipedia · Source
Encyclopedia
n/a
n/a n/a
The article gives the common names violet-pored bracket fungus, purple tooth and violet-toothed polypore. It says the cap grows to 1 to 7.5 cm across, starts violet and fades to white and brown with violet kept at the margin for a time. It is a saprobe on hardwood stumps and logs, recorded on at least 65 tree hosts, rarely on conifers. It says the fungus is sometimes confused with Trichaptum abietinum (nearly always on conifers), T. byssogenum, T. fuscoviolaceum and Skeletocutis lilacina, and that it is inedible.
Description and look-alikes
Methods, limits and funding

Outcomes: Description and look-alikes

Limitations: A general encyclopedia read on 2026-10-25; its edibility and look-alike statements were not checked against a field guide. Not an identification guide.

Funding and conflicts: Not applicable

Read: article text (extract)

Xie 2025
Trichaptum biforme (Pallidohirschioporus biformis) genome decoding provides insights into carbohydrate degradation and polysaccharide synthesis.
Genomics · PMID 40349991 · DOI
Genome sequencing
Trichaptum biforme
The fungus T. biforme (genome) n/a
The genome is 50.71 Mb in 13 chromosome-level pieces and encodes 15,302 predicted genes. 375 genes were predicted to make carbohydrate-active enzymes. The authors link this to its ability to break down wood (lignocellulose). The fungus is described as a white-rot fungus.
Genome size and gene content
Methods, limits and funding

Outcomes: Genome size and gene content

Limitations: Genetics only; nothing on health, food or safety.

Funding and conflicts: The authors declare no competing financial interests (abstract).

Read: abstract

Yang 2013
Two new drimane sesquiterpenoids from cultures of the basidiomycete Trichaptum biforme.
Natural Products and Bioprospecting · Source · DOI
Laboratory study (chemistry and cell lines)
Trichaptum biforme (culture)
Five human cancer cell lines in culture Two new drimane sesquiterpenoids and five known compounds from laboratory cultures
Laboratory culture (not wild fruiting bodies)
Two new drimane sesquiterpenoids (1 and 2) and five known compounds were isolated from the fungus. Compounds 1 and 2 had negligible cytotoxicity against five human cancer cell lines.
Structures; cytotoxicity against five human cancer cell lines
Methods, limits and funding

Outcomes: Structures; cytotoxicity against five human cancer cell lines

Limitations: Abstract read from the open-access PMC record (PMC4131575); it is not in PubMed. Culture compounds may differ from those in the wild fruiting body.

Funding and conflicts: Not stated in the abstract

Read: abstract (PMC record)

What we do not know yet

  • No human trial, case report or safety study of violet-toothed polypore was found.
  • No animal study of any health outcome was found.
  • The immune result comes from one extract in one paper; the 1947 antibiotic paper was read by title only.
  • No identification, edibility or toxicology report was read, and no metal value for this species was in the abstract we read.
  • LiverTox and LactMed entries were not found; EMA, NCCIH and MSK pages were not checked.

How new research is added

New studies are found by a saved PubMed search and placed in a review queue. A person reads each one before it changes any evidence rating or safety wording. New publications never change ratings automatically.

Lab markers

What changed in blood or saliva tests during trials. A changed number is not the same as feeling or being healthier, and we give no "normal ranges".

Other 6

●

IL-1 beta and TNF-alpha release from THP-1 cells

Increased in trials

Amounts of two inflammatory messenger proteins released by a human immune-type cell line in a dish.

Not enough evidence
Results and what it means

Why it was measured

A first look at whether an extract activates immune cells.

Statistical vs. clinical meaning

Cell-dish result only.

Safety implication

More inflammatory messengers is not a measure of benefit or safety.

StudyResultPeopleProduct
2The hot-water polysaccharide extract significantly raised both messengers at 10 and 320 ug/mL (p < 0.01).THP-1 cell lineHot-water polysaccharide extract (TBP)

2

●

Natural killer cell activity and IFN-gamma release

Increased in trials

How strongly natural killer cells kill target cells and release IFN-gamma in culture.

Not enough evidence
Results and what it means

Why it was measured

Natural killer cells are part of the body's first-line immune defence.

Statistical vs. clinical meaning

Cell-dish result only; combined with IL-2, so the extract alone is not shown to do this.

Safety implication

Not a measure of safety.

StudyResultPeopleProduct
2Extract (320 ug/mL) plus IL-2 significantly increased killing activity and IFN-gamma release versus control (p < 0.01).NK cells in cultureHot-water polysaccharide extract with IL-2

2

●

Growth of human cancer cell lines in a dish

No change in trials

Whether cancer cells grow more slowly or die when a compound or extract is added.

Not enough evidence
Results and what it means

Why it was measured

A routine first screen for new molecules.

Statistical vs. clinical meaning

Mostly null lab results.

Safety implication

Not a measure of safety or of treating cancer.

StudyResultPeopleProduct
12Two new drimane sesquiterpenoids had negligible cytotoxicity against five cancer cell lines.Human cancer cell linesCompounds from lab cultures
7Five of six fungi tested were reported active; T. biforme was not among the five named.Leukemia and solid-tumour cell linesHot-water and methanol-chloroform extracts of mycelium

12 7

●

Hyaluronidase inhibition in a test tube

Inhibited in trials

How much an extract or compound slows an enzyme that breaks down hyaluronic acid.

Not enough evidence
Results and what it means

Why it was measured

A common first screen for anti-inflammatory and skin-related chemistry.

Statistical vs. clinical meaning

Lab screening result only.

Safety implication

Says nothing about safety or effects in people.

StudyResultPeopleProduct
8Ergosterol peroxide glucoside 91%, betulin 32%; chloroform extract 47% at 5 mg/mL and 79 to 97% for chloroform and methanol extracts at 10 and 20 mg/mL.Enzyme assayExtracts and isolated compounds from wild fruiting bodies

8

↕

Acetylcholinesterase and butyrylcholinesterase inhibition

Mixed results in trials

How much an extract slows two enzymes that break down acetylcholine and related esters.

Not enough evidence
Results and what it means

Why it was measured

A routine screen related to memory research chemistry.

Statistical vs. clinical meaning

Lab screening result only; not a memory or brain outcome.

Safety implication

Not a measure of safety.

StudyResultPeopleProduct
8Methanol and chloroform extracts blocked butyrylcholinesterase (about 51% at 40 mg/mL) but not acetylcholinesterase; hydroxydihydrobovolide was the main active compound.Enzyme assayExtracts of wild fruiting bodies

8

●

Bacterial growth (MIC) in a test tube

No change in trials

The lowest amount of extract that stops visible bacterial growth.

Not enough evidence
Results and what it means

Why it was measured

A first screen for germ-killing chemistry.

Statistical vs. clinical meaning

Null lab result.

Safety implication

Not a measure of safety or of treating infection.

StudyResultPeopleProduct
8No antibacterial effect on seven bacterial strains (MIC above 400 ug/mL) for the three fungal extracts.Seven bacterial strainsMethanol, chloroform and hexane extracts of wild fruiting bodies

8

Safety

What studies and official sources say about side effects, medicines and who should check first. Each point shows what kind of evidence it comes from.

Main points to know 5
  • Wild fungus: do not eat or use it on a guess. Violet-toothed polypore is a wild, leathery bracket on dead wood. Wikipedia lists look-alikes (Trichaptum abietinum, T. byssogenum, T. fuscoviolaceum and Skeletocutis lilacina) and calls this fungus inedible. We found no field guide or toxicology report, so this page gives no identification help and no advice to eat, brew or apply it. If someone ate a wild fungus and you are unsure what it was, call your local poison centre (in the US, Poison Help at 1-800-222-1222). Identification caution 10
  • No human safety data were found. We found no clinical trial, case report or poison-centre report for this fungus. That means the risks are unknown, not that there are none. Nothing here is a safety all-clear. None 8 4
  • Not a turkey tail substitute. It is sometimes compared with turkey tail (Trametes versicolor) because of the similar look and shared habitat. Turkey tail's research (PSK, PSP, trials in cancer care) concerns a different fungus and does not transfer. The only polysaccharide work on this fungus is a cell-dish study. Naming 2 7
  • The name has changed. Recent papers call it Pallidohirschioporus biformis (syn. Trichaptum biforme). GBIF still lists Trichaptum biforme as the accepted name and did not match the newer one on 2026-10-25. Check the Latin name on anything you read or buy. Naming 1 8
  • No known consumer product, so label quality cannot be judged. We found no supplement made from this fungus. For medicinal mushrooms in general, the US National Cancer Institute says ingredients may vary considerably from lot to lot and there is no guarantee that label ingredients are present. Authoritative guidance 5
Side effects 1
EffectHow oftenSeverity and recoveryEvidence
No adverse effects have been reported, but none have been looked for in people
Absence of reports in the sources we read is not proof of safety.
Unknownunknown
Not applicable
None
Liver

We found no case report or trial linking this fungus to liver injury. NCBI Books searches on 2026-10-25 for Trichaptum and for Pallidohirschioporus returned no LiverTox entry. 4

How often. No liver reports found; this is not proof of liver safety.

Monitoring. No agency monitoring advice exists in the sources we read. People with liver disease should ask a doctor before using any medicinal fungus.

This is a safety connection. It is not evidence that Violet-toothed polypore supports liver health.

Medicines and supplements 3
WithWhy it mattersImportanceEvidenceWhat to do
Any medicine, including blood thinners and immune-suppressing medicines
prescription
Unknown. No interaction study or case report was found. The only immune work is a cell-dish study.None Not enough evidence Ask your prescriber or pharmacist before using any medicinal fungus.
Herbal products and other supplements
supplement
Unknown.None Not enough evidence Tell your pharmacist about every product you use.
Food and alcohol
food
Unknown. It is not a food.None Not enough evidence Not applicable.
Who should check first 4
SituationAdviceEvidence
Pregnancy and breastfeedingNo safety data were found, so it is not known whether it is safe. Ask a doctor. Our NCBI Books search found no LactMed entry.None 4
Children and babiesNo safety data were found. Ask a doctor before giving any medicinal fungus to a child.None
Mushroom allergy, asthma or a history of reactions to fungi or mouldsAllergy to this fungus has not been studied. Take extra care and ask a doctor. This is general caution, not from a source on this fungus.General caution
Before surgery, or with immune disease or an organ transplantNothing is known. Ask your doctor before using any medicinal fungus.None
Overdose, product quality and regulators

Summary. No toxicity study in people or animals was found.

Human doses studied. No human study. This page gives no amounts and none are advised.

Overdose response. No description was found. If someone becomes unwell after eating any wild fungus, seek medical help or call poison control and keep a sample if you can.

Toxic parts. Not described in the sources read.

A 2021 Turkish study measured metals and minerals in 20 wild mushroom species that included this one, but its abstract gives only ranges across all species, not a value for this fungus. Wild fungi can take up substances from their wood and surroundings.

Metals in wild mushrooms. Across the 20 species, mercury ranged from 14.03 to 37.81 and cadmium from 0.09 to 2.4 mg/kg dry weight; some edible species (not this one) exceeded legal intake limits. The authors advise controlled consumption. No separate figure for this fungus is in the abstract. 3

BodyActionDate
US National Cancer Institute (PDQ) (United States)States that the FDA has not approved medicinal mushrooms as a treatment for cancer or any other medical condition, and that supplement ingredients may vary considerably from lot to lot. The page has no section on this fungus. source
LiverTox / LactMed (US NIH) (United States)No entry found for Trichaptum or Pallidohirschioporus by NCBI Books search. source2026-10-25
When to get medical help
  • Itching, hives, swelling of the lips, tongue or face, wheeze or trouble breathing after eating, handling or inhaling a fungus: get emergency help now (general advice, not from a source on this fungus).
  • Repeated vomiting, severe stomach pain, diarrhoea, confusion or yellow skin or eyes after eating any wild fungus: get medical help now and call your local poison control number. Keep a sample of the fungus if you can.
  • A wound that bleeds heavily, looks infected, or does not heal: do not rely on any fungus; get medical care.

If someone may be poisoned or in a crisis, contact a clinician or emergency service straight away. In the US, Poison Control is 1-800-222-1222.

General information only, not medical advice. Ask a clinician or pharmacist before use, especially with medicines, in pregnancy or with a health condition. See the Natural Remedy Safety guide.

Frequently asked questions

What is violet-toothed polypore?

It is a leathery, purple-edged bracket fungus that rots dead hardwood. Its scientific name is Trichaptum biforme, and recent papers call it Pallidohirschioporus biformis. We found no human research on it.

1 8

Is violet-toothed polypore edible?

We found no source that describes it as food and no nutrition data, and Wikipedia calls it inedible. We give no advice to eat it. Never eat a wild fungus because of a description.

10

Is it the same as turkey tail?

No. Turkey tail is Trametes versicolor, with decades of research on PSK and PSP. Violet-toothed polypore has only laboratory studies, and turkey tail findings do not apply to it.

7 2

Does it have proven health benefits?

No. The research is a few laboratory papers. A hot-water extract changed immune messengers in a cell dish. That does not show a benefit in people.

2

Does it help the immune system?

Not shown. In a cell dish, a hot-water polysaccharide extract raised some immune messengers and, with IL-2, natural killer cell activity. It was not tested in animals or people.

2

Does it fight cancer?

No evidence. Compounds from lab cultures had negligible or weak effect on human cancer cell lines, and a 2018 screen of six wood-decay fungi did not list this one among the active ones.

12 7

Does it fight germs or infections?

Not shown. A 2026 test of extracts from wild fruiting bodies found no antibacterial effect on seven bacteria. A 1947 report of an antibacterial compound from cultures was not available to read in full.

8 6

Is it safe?

Not known. We found no safety study in people, no case reports and no data for pregnancy, breastfeeding or children. Ask a doctor or pharmacist first.

4 5

Can I tell it from look-alikes myself?

No. Wikipedia lists several similar wood fungi, and wild fungi cannot be safely identified from a description, a photo or an app. Ask a trained local expert.

10

Has the name changed?

Recent papers call it Pallidohirschioporus biformis. GBIF still lists Trichaptum biforme as accepted and did not match the newer name when we checked.

1 8

Does it interact with medicines?

Unknown. No interaction study or case report was found. Ask a pharmacist before using any medicinal fungus.

4

Can I buy a violet-toothed polypore supplement?

We found no consumer product made from it. For mushroom supplements in general the US National Cancer Institute says label contents are not guaranteed, so check the Latin name on any turkey tail label.

5

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Editorial transparency
Written by
AlternativeMed editorial team. Research compiled with AI assistance, then checked against PubMed records.
Medical review
None. This page has not been reviewed by a physician or pharmacist.
First published
2026-10-25
Last substantive update
2026-10-25
How we research
We read PubMed records and abstracts for 7 papers on this fungus (immune cells, enzymes, cancer cell lines, chemistry, two genome papers) plus a 1947 record by title, parts of the open-access 2026 full text, the open-access 2013 chemistry abstract and a 2021 element study that included the species. We checked the name in GBIF, read a Wikipedia extract for description and look-alikes, read the National Cancer Institute medicinal mushrooms page, and searched NCBI Books for LiverTox and LactMed entries. Certainty ratings are the compiler's own reading.
How we rate evidence
See "How we rate evidence" in the Evidence tab.
Independence
No product is promoted on this page. No affiliate links are shown. This page is information, not a recommendation to use violet-toothed polypore.
Sources 12

Each source was opened and checked. Where we read only the abstract, it says so. The small numbers in the text point here.

  1. GBIF. GBIF Backbone Taxonomy: Trichaptum biforme. GBIF. 2026. (database record)
  2. Habibi E, Hemmati P, Arabnozari H, Khalili HA, Sharifianjazi F, Enderami SE, Sarker SD, Hassannia H, Nahar L. Phytochemical analysis and immune-modulatory potential of Trichaptum biforme polysaccharides: Implications for cancer.. International Journal of Biological Macromolecules. 2024. PMID 39284468. DOI 10.1016/j.ijbiomac.2024.135691. (abstract)
  3. Keskin F, Sarikurkcu C, Akata I, Tepe B. Element concentration, daily intake of elements, and health risk indices of wild mushrooms collected from Belgrad Forest and Ilgaz Mountain National Park (Turkey).. Environmental Science and Pollution Research. 2021. PMID 33982259. DOI 10.1007/s11356-021-14376-6. (abstract)
  4. National Cancer Institute. NCI PDQ: Medicinal Mushrooms (health professional version). National Cancer Institute. 2024. (page text)
  5. Robbins WJ, Kavanagh F, Hervey A. Antibiotics from Basidiomycetes: II. Polyporus biformis.. Proceedings of the National Academy of Sciences USA. 1947. PMID 16588738. DOI 10.1073/pnas.33.6.176. (title only (PubMed record))
  6. Shnyreva AV, Shnyreva AA, Espinoza C, Padron JM, Trigos A. Antiproliferative Activity and Cytotoxicity of Some Medicinal Wood-Destroying Mushrooms from Russia.. International Journal of Medicinal Mushrooms. 2018. PMID 29604909. DOI 10.1615/IntJMedMushrooms.2018025250. (abstract)
  7. Suratno S, Felegyi-Toth CA, Studzinska-Sroka E, Papp V, Boldizsar I, Kincses A, Gati T, Zalewski P, Beni S, Vanyolos A. Butenolides and triterpenoids from the fungus Pallidohirschioporus biformis (syn. Trichaptum biforme): isolation, structure determination and bioactivity profile.. Frontiers in Fungal Biology. 2026. PMID 42358799. DOI 10.3389/ffunb.2026.1737900. (abstract and open-access full text (parts))
  8. Wei J, Jiang JQ, Tang D, Hu XS, Li HW, Qi J. The first complete mitochondrial genome of Trichaptum biforme (Fr.) Ryvarden 1972 within the family Trichaptaceae, Hymenochaetales.. Mitochondrial DNA Part B. 2026. PMID 42205523. DOI 10.1080/23802359.2026.2677956. (abstract)
  9. Wikipedia. Wikipedia: Trichaptum biforme. Wikipedia. 2026. (article text (extract))
  10. Xie X, Chen RX, Song Y, Lin C, Zhang M, Li M, Qi J. Trichaptum biforme (Pallidohirschioporus biformis) genome decoding provides insights into carbohydrate degradation and polysaccharide synthesis.. Genomics. 2025. PMID 40349991. DOI 10.1016/j.ygeno.2025.111057. (abstract)
  11. Yang XY, Feng T, Ding JH, Li ZH, Li Y, Fan QY, Liu JK. Two new drimane sesquiterpenoids from cultures of the basidiomycete Trichaptum biforme.. Natural Products and Bioprospecting. 2013. DOI 10.1007/s13659-013-0030-y. (abstract (PMC record))
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.