Habits for Immune Health: Sleep, Activity, Nutrition, Smoking and Alcohol
What research and health agencies say about sleep, physical activity, nutrition, smoking, alcohol and handwashing for immune health, with the strength of evidence for each.
Content last updated . This page has not been medically reviewed.
Overview
Everyday habits cannot make you immune to infections, but several are linked to how the body copes with them. This page sorts what is well supported from what is only suggestive. Labels: established recommendation, promising but limited, mixed, insufficient evidence.At a glance
| Habit | What the sources found | Strength of evidence |
|---|---|---|
| Sleep | Shorter sleep before virus exposure was associated with more colds [1] | Promising but limited |
| Physical activity | No change in number of infections, but possibly milder symptoms [2] | Mixed |
| Not smoking | Smokers had higher odds of hospital admission after influenza [3] | Observational, consistent |
| Limiting alcohol | Alcohol affects immune responses; chronic heavy use raises infection susceptibility [4] | Review; strongest for heavy use |
| Handwashing | Protects you and others from illnesses such as flu [5] | Established recommendation |
| Enough food and protein | Malnutrition can cause acquired immunodeficiency [6] | Established for severe shortage |
Sleep
In a study of 164 healthy adults who were given a cold virus, those sleeping less than 5 hours or 5 to 6 hours a night (measured by wrist monitor) were more likely to develop a clinical cold than those sleeping more than 7 hours. Sleep broken into pieces was not linked to cold risk. [1] This was one study and shows association, not proof that sleeping more prevents colds. For sleep routines, see the NHS tips: a regular schedule, relaxing before bed and avoiding alcohol and nicotine 1 to 2 hours before bed. [7] More in Better Sleep.Physical activity
A Cochrane review of 14 trials in 1,377 adults found no difference between exercise and no exercise in the number of respiratory infections, though exercise reduced symptom severity and the number of symptom days in a few studies. The authors rate certainty as low because of small studies and bias. [2] The NHS general guideline for adults is at least 150 minutes of moderate activity or 75 minutes of vigorous activity a week, plus strengthening on 2 days. [8] Label: mixed for infections; the guideline stands for general health. When you are ill with a cold or flu, the NHS advises rest. [9][10]Nutrition
MedlinePlus lists malnutrition, especially too little protein, as a cause of acquired immunodeficiency. [6] The NHS says you should be able to get the vitamin C and zinc you need from a varied, balanced diet. [11][12] For supplements, see vitamin C, vitamin D and zinc. For food guides, see functional foods by wellness goal. We did not find solid evidence that any single food "boosts" immunity: proper evidence not found in the sources we read.Smoking
A meta-analysis of 12 observational studies found ever-active smokers had higher odds of hospital admission (odds ratio 1.5) and intensive-care admission (2.2) after influenza than never-smokers, with no clear link to deaths. Secondhand smoke was linked to admissions only in children under 15. [3] The NHS says smoking can make cold symptoms worse. [9] If you want to quit, your clinician or national quitline can help.Alcohol
A review says even moderate alcohol can influence immune responses, though often the effect is a subclinical weakening that matters only after an infection or injury. Chronic heavy drinking interferes with both innate and adaptive immunity and raises susceptibility to viral and bacterial infections. [4] We did not find a source in this review that sets a safe amount for immunity.Handwashing and hygiene
Washing with soap and water for about 20 seconds, especially after coughing, sneezing, using the toilet and before eating, helps stop infections spreading. [5] Details in vaccines and infection prevention.When to get help
Habits do not replace medical care. If you get repeated or severe infections, see a clinician: getting sick often. If sleep trouble is a problem, see insomnia. For stress, see Stress and Relaxation. Emergency signs such as severe trouble breathing: use your local emergency number (911 in the US).Frequently asked questions
Does lack of sleep make you more likely to catch a cold?
In one study of 164 healthy adults, sleeping under 6 hours was associated with a higher chance of developing a cold after virus exposure. [1]
Does exercise prevent colds?
A Cochrane review found no difference in number of infections, but exercise may reduce symptom severity. Certainty was low. [2]
Does smoking weaken immunity?
Smokers had higher odds of hospital admission after influenza in a meta-analysis. [3]
Does alcohol affect the immune system?
Yes, even moderate amounts can influence immune responses, and chronic heavy use raises susceptibility to infection. [4]
References
- Prather AA, et al. Behaviorally assessed sleep and susceptibility to the common cold. Sleep. 2015. PubMed record read 2026-10-22.
- Cochrane review. Exercise versus no exercise for the occurrence, severity, and duration of acute respiratory infections. Cochrane Database Syst Rev. 2020. PubMed record read 2026-10-22.
- Smoking and influenza-associated morbidity and mortality: a systematic review and meta-analysis. Epidemiology. 2019. PubMed record read 2026-10-22.
- Szabo G, Saha B. Alcohol's effect on host defense. Alcohol Res. 2015. PubMed record read 2026-10-22.
- NHS. How to wash your hands. Read 2026-10-22.
- MedlinePlus Medical Encyclopedia. Immunodeficiency diseases. Read 2026-10-22.
- NHS. How to fall asleep faster and sleep better. Read 2026-10-22.
- NHS. Physical activity guidelines for adults aged 19 to 64. Read 2026-10-22.
- NHS. Common cold. Read 2026-10-22.
- NHS. Flu. Read 2026-10-22.
- NHS. Vitamin C (page last reviewed 3 August 2020). Read 2026-10-22.
- NHS. Other vitamins and minerals, including zinc (page last reviewed 3 August 2020). Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.