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Green cardamom pods beside a small dropper bottle
Green cardamom pods; the essential oil comes from the seeds inside.

Essential Oils & Aromatherapy · Essential oil

Cardamom Oil

Elettaria cardamomum (L.) Maton · also called Green cardamom oil, true cardamom oil, cardamom seed oil

Cardamom oil is the sweet, spicy, slightly cool-smelling oil taken from the seeds of green cardamom. People use it in aromatherapy. In people, the research is two small nausea studies where the oil was breathed from a pad, one of them a four-oil blend. Everything else is lab or animal work. The main caution: never swallow the oil, never use it undiluted, and keep it away from the faces of young children and from pets.

General information, not medical advice. Last substantive update · Not medically reviewed. A named clinician has not signed off on this page. How this page is made

About Cardamom Oil

Cardamom oil is a sweet, spicy aromatherapy oil. In people, the research is one small trial of the oil alone (nausea around a cesarean section) and one trial of a four-oil blend (nausea after surgery); the rest is lab or animal work. Safety comes first: do not swallow it, do not use it undiluted, keep it away from young children's faces and from pets, and ask a doctor about pregnancy.

What cardamom oil is

Cardamom oil is the essential oil from the seeds of green cardamom, Elettaria cardamomum, a plant in the ginger family. GBIF lists the name as accepted.

The main compounds are 1,8-cineole and alpha-terpinyl acetate. In one oil, 1,8-cineole was 45.6% and alpha-terpinyl acetate 33.7%; in a CO2 extract, they were 21.4% and 42.3%. Another sample made with a new method had geranyl oleate and oleic acid among its main compounds. Oils differ with the method, and Poison Control says it can be hard to know what is in a bottle.

Black cardamom is a different plant, and the spice, tea and herb have their own pages.

5 12 11 2 17

What the human evidence shows

In a trial of 70 mothers having a cesarean section under spinal anesthesia, those who breathed cardamom oil from a gauze pad had fewer nausea episodes (37.1% against 65.7%), less retching (20% against 45.7%) and needed less anti-nausea medicine (37.1% against 65.7%) than those who breathed saline. Nausea scores fell in both groups.

In a trial of 301 adults with nausea after day surgery, a blend of ginger, spearmint, peppermint and cardamom oils reduced nausea more than saline, and so did ginger oil alone. That does not show what cardamom does by itself.

A review of inhaled aromatherapy for chemotherapy nausea included three studies that reduced nausea only, using chamomile, ginger or cardamom oil. The authors say small samples and many different methods mean the results cannot be generalised. A study of oil vapours for blood pressure tested cardamom among 23 oils, but its abstract gives no cardamom result.

We rate this low at best. The trials are small, the scent cannot be hidden well, and funding is not stated in the abstracts.

10 8 23 25

Lab and animal findings

In a 2026 dish test, cardamom oil was the strongest of twelve oils against a tooth-decay bacterium. It stopped growth at 2.5% oil and killed the bacteria at 5.0%. The bacteria's harm genes were turned up, which the authors read as a stress response. A second 2026 study tested water and ethanol extracts, not the oil, and found strong anti-inflammatory test results; the authors call it preliminary.

In mice, the oil gave negligible protection against seizures and caused movement problems at higher amounts. In rats, the highest single amount swallowed killed one of three, while lower amounts for 28 days caused no significant changes. Neither study gives a safe amount for people. None of this shows a benefit in people.

22 7 12 1

Oil, spice and extracts are different

A review of eight trials of cardamom eaten as food or supplement reports lower inflammation markers and lower blood pressure, with the authors urging caution because there are few studies. That is the spice, not the oil, and it does not support using the oil. Our pages on cardamom as a spice, herb and tea cover those.

6 7

At a glance

Traditional uses history, not proof

  • Cardamom is one of the world's best-known spices and is used in the traditional medicine of many cultures, as the authors of a 2026 lab paper say.
  • The oil itself has no traditional-use status that we could verify from the sources read.

Studied for research

  • Nausea during a cesarean section, oil breathed from a pad, low
  • Nausea after day surgery, four-oil blend including cardamom, low
  • Nausea with chemotherapy, inhaled aromatherapy review, insufficient
  • Blood pressure, inhaled vapours, no cardamom result, insufficient
  • Tooth-decay bacteria, lab dish only, very-low

Main compounds

  • 1,8-Cineole, a main component
  • alpha-Terpinyl acetate, a main component
  • Linalyl acetate, limonene, linalool and sabinene in smaller amounts

Common forms

  • Essential oil from the seeds (steam, water or CO2 extraction)
  • Gauze pad inhaled in nausea trials
  • Seed, powder and extracts (different products)

Research links: Poison Control: Essential oils · FDA: Aromatherapy · Cesarean nausea trial, abstract · Four-oil blend nausea trial, abstract · Tooth-bacteria lab study, abstract · EMA: Eucalyptus oil (a similar cineole-rich oil) · Research Library · Genes & Biomarkers Library

What it is and its history

Accepted scientific name
Elettaria cardamomum
Naming authority
(L.) Maton
Common names
Green cardamom (English); True cardamom (English); Cardamom (English)
Family or group
Zingiberaceae (ginger family), per GBIF.
Classification
Plantae > Tracheophyta > Liliopsida > Zingiberales > Zingiberaceae > Elettaria > Elettaria cardamomum
Native range
Not checked in a source we read.
Habitat
Not checked.
What it looks like
Part used: The oil is made from the seeds inside the pods (the seed oil in the 2026 studies). This page does not describe how to recognise the plant.
Look-alikes and adulterants
Name: Black cardamom; Note: A different plant sold as a spice, with its own page. Results for green cardamom oil do not carry over. We did not verify its species name for this page.
Sustainability and conservation
Not checked.

Traditional use and history history, not clinical proof

Tradition or eraDocumented useSource
Spice and traditional medicineThe authors of a 2026 lab paper call cardamom one of the world's most famous spices and say it is also applied in the traditional medicine of many cultures. This is the authors' statement; we did not check the history ourselves.Hitl 2026

Traditional use shows how it was used. It does not show that it works or is safe today.

What is inside, and how it may work

What it contains and how those compounds act in cells and animals. Laboratory and animal mechanisms are not proven effects in people.

Main compounds

CompoundFamilyWhere it is concentratedActivity studiedLevel of evidence
1,8-Cineole (eucalyptol)
PubChem 2758
monoterpene oxideSeed oil
45.6% in an oil used in a mouse study; 21.4% in a CO2 extract. Varies by sample.
Also the main compound of eucalyptus oil. The EU rule for young children and seizures is for eucalyptus oil; we apply it by caution only. 18 12 11 3Lab / regulatory (other oil)
alpha-Terpinyl acetate
PubChem 111037
monoterpene esterSeed oil
33.7% (mouse study oil); 42.3% (CO2 extract).
Main compound in several samples; no activity claimed here. 19 12 11 7Laboratory
Linalyl acetate
PubChem 8294
monoterpene esterSeed oil
8.2% of a CO2 extract.
No activity claimed. 20 11Laboratory
Sabinene
PubChem 18818
monoterpeneSeed oil
3.8% (mouse study oil).
No activity claimed. 21 12Laboratory
Limonene and linaloolmonoterpenesSeed oil
Limonene 5.6% and linalool 5.4% of a CO2 extract; linalool is also named among the compounds in the 2026 tooth-bacteria study.
No activity claimed here. PubChem CIDs not looked up. 11 22Laboratory

Mechanisms, receptors and pathways

Target or pathwayGene or receptorWhat was foundLevel
Streptococcus mutans growth and biofilmVirulence genes gtfB, gtfC, gtfD, ldh, gbpB, vicR measuredThe oil reduced growth, biofilm and viability in a dish; virulence genes were turned up, read by the authors as a stress response. 22Laboratory research
Seizure modelsNone namedNegligible protection in two mouse seizure models; movement toxicity at higher amounts. 12Animal research
How inhaled oil might ease nauseaNone namedNot explained in the trials read. 10Not assessed

Absorption, metabolism and elimination

Absorption
Not established in the sources read.
Distribution
Not established.
Metabolism
Not established.
Elimination
Not established.
Bioavailability
Not established.

1

Isolated compounds versus whole extracts

Cardamom essential oil (volatile terpenes), cardamom seed or powder eaten as food, and water or ethanol extracts are different products. The nausea trials used the oil on a gauze pad; the blood pressure and inflammation meta-analysis (8 trials) is about cardamom eaten as food or supplement; the 2026 lab activity tests were on extracts. Results for one product do not carry over to another.

Nutritional composition

Cardamom oil is not a nutrient and has no nutritional role.

7benefits and uses looked at
25studies and sources checked
Low certaintybest evidence rating found
3lab markers tracked in trials

2 low certainty2 very low certainty2 not enough evidence1 evidence against

What is Cardamom Oil good for?

The uses people ask about and how strong the evidence is for each. Read the certainty label first: only two small trials in people involve cardamom oil, and one of them used a blend.

Nausea during and after cesarean section (breathing cardamom oil)Low certaintyIn one small Iranian trial of 70 mothers, those who breathed cardamom oil from a gauze pad had fewer nausea episodes, less retching and needed less anti-nausea medicine than mothers who breathed plain saline. Nausea in the recovery room (a four-oil blend that included cardamom)Low certaintyIn a trial of 301 adults who felt sick after day surgery, breathing a blend of ginger, spearmint, peppermint and cardamom oils reduced nausea more than a saline pad. Cardamom was one of four oils, so this does not show that cardamom oil alone helps. Nausea with chemotherapy (inhaled aromatherapy review)Not enough evidenceA review of 11 studies found promising results for breathing oils directly from a pad. Three studies reduced nausea only, using chamomile, ginger or cardamom oil. Filling a room with the scent, and use in children, did not help. Blood pressure (breathing oil vapours)Not enough evidenceA large Russian study tested vapours of 23 essential oils, including cardamom, on women with high blood pressure. The abstract names oils that lowered it, and oils that did not. Cardamom is on neither list. Slowing tooth-decay bacteria (lab dish only)Very low certaintyIn a 2026 lab study, cardamom oil was the strongest of twelve oils at stopping Streptococcus mutans, a main cavity bacterium, in a dish. It has not been tried in a mouth. Antioxidant and anti-inflammatory tests (lab; extracts, not the oil)Very low certaintyA 2026 lab study analysed the chemistry of cardamom oil but ran its activity tests on water and ethanol extracts of the seeds. Those showed strong results in anti-inflammatory tests and moderate antioxidant activity. This is not a test of the oil. Protection against seizures (mouse test)Evidence againstIn mice, cardamom oil gave only a negligible protection against induced seizures, and the oil and an extract both caused movement problems at higher amounts.

Benefits, one by one

Each card is a research question, not a promise. Tap a goal to filter. Open a card to see the studies, doses and limits.

Nausea during and after cesarean section (breathing cardamom oil)

Low certainty

In one small Iranian trial of 70 mothers, those who breathed cardamom oil from a gauze pad had fewer nausea episodes, less retching and needed less anti-nausea medicine than mothers who breathed plain saline.

1 studiesNot covered. This page gives no amounts and no ways of using the oil.

Studies, doses and limits

What the trials found

One single-blind randomized placebo-controlled trial, 70 mothers, spinal anesthesia, elective cesarean section.

Results

Nausea episodes 37.1% vs 65.7%, retching 20% vs 45.7%, anti-nausea medicine 37.1% vs 65.7%, cardamom oil vs saline placebo. Nausea scores fell in both groups, and fell more with cardamom after allowing for starting level.

Effect sizes as reported

Episodes P = .006, retching P = .028, medicine P = .009. No confidence intervals in the abstract.

Why this rating

One small trial at one site. A scent is hard to hide, so participants may have known which pad they had. Funding is not stated in the abstract and nobody has repeated it.

Form and dose studied

Not covered. This page gives no amounts and no ways of using the oil.

Who was studied

Mothers having a planned cesarean under spinal anesthesia in Iran.

Limits

Small; one centre; blinding limits; only the surgery period.

Why researchers looked

Nausea after surgery is common, and some people want a non-drug extra.

Traditional use

Not covered by the sources read.

Proposed mechanism Preliminary mechanism

Not established in the study read.

A proposed mechanism does not show that the effect happens in people.

The oil is breathed from a pad, not swallowed. Never swallow essential oil. See the Safety tab.

10

Nausea in the recovery room (a four-oil blend that included cardamom)

Low certainty

In a trial of 301 adults who felt sick after day surgery, breathing a blend of ginger, spearmint, peppermint and cardamom oils reduced nausea more than a saline pad. Cardamom was one of four oils, so this does not show that cardamom oil alone helps.

1 studiesNot covered.

Studies, doses and limits

What the trials found

One randomized trial with several groups, 303 enrolled and 301 analysed, one US surgery centre.

Results

Nausea fell more with the blend (P < 0.001) and with ginger oil alone (P = 0.002) than with saline. Alcohol did not help. Fewer anti-nausea medicines were requested after the blend or ginger.

Effect sizes as reported

P values only in the abstract.

Why this rating

A fairly large trial, but cardamom is one of four oils, ginger alone also worked, so cardamom's own part is unknown. One centre; funding not stated in the abstract.

Form and dose studied

Not covered.

Who was studied

Adults with nausea after ambulatory surgery in the US.

Limits

Blend, not cardamom alone; scent cannot be well hidden.

Why researchers looked

Anti-nausea drugs do not always prevent nausea after surgery.

Traditional use

Not covered by the sources read.

Proposed mechanism Preliminary mechanism

Not established in the study read.

A proposed mechanism does not show that the effect happens in people.

The trial used a blend of four oils. See the Safety tab.

8

Nausea with chemotherapy (inhaled aromatherapy review)

Not enough evidence

A review of 11 studies found promising results for breathing oils directly from a pad. Three studies reduced nausea only, using chamomile, ginger or cardamom oil. Filling a room with the scent, and use in children, did not help.

1 studiesNot covered.

Studies, doses and limits

What the trials found

A systematic review of 11 studies (9 adult, 2 child). The abstract does not say which study used cardamom or how big it was.

Results

Seven of nine adult studies were statistically significant. The authors say small samples and many different oils and methods mean the results cannot be generalised.

Effect sizes as reported

Not given in the abstract.

Why this rating

Cardamom is one of several oils in a few small studies that we could not identify from the abstract. The authors urge larger, better studies.

Form and dose studied

Not covered.

Who was studied

People having chemotherapy, mostly women with gynecologic cancers.

Limits

Mixed oils and methods; small samples; cardamom study not identified here.

Why researchers looked

Chemotherapy nausea affects many people despite modern drugs.

Traditional use

Not covered.

Proposed mechanism Preliminary mechanism

Not established.

A proposed mechanism does not show that the effect happens in people.

See the Safety tab.

23

Blood pressure (breathing oil vapours)

Not enough evidence

A large Russian study tested vapours of 23 essential oils, including cardamom, on women with high blood pressure. The abstract names oils that lowered it, and oils that did not. Cardamom is on neither list.

1 studiesNot covered.

Studies, doses and limits

What the trials found

849 women aged 55 to 89 with hypertension; vapours with a relaxation session against relaxation alone.

Results

No cardamom result is given in the abstract. Clove and coriander oils were among those that lowered pressure, and fennel was among those that did not.

Effect sizes as reported

Not given in the abstract.

Why this rating

The abstract does not report a cardamom result, and describes the study design only briefly. We do not claim any effect.

Form and dose studied

Not covered.

Who was studied

Older women with hypertension, Russia.

Limits

No cardamom result; design details thin; Russian-language paper.

Why researchers looked

People look for gentle ways to lower blood pressure.

Traditional use

Not covered.

Proposed mechanism Preliminary mechanism

Not established.

A proposed mechanism does not show that the effect happens in people.

See the Safety tab.

25

Slowing tooth-decay bacteria (lab dish only)

Very low certainty

In a 2026 lab study, cardamom oil was the strongest of twelve oils at stopping Streptococcus mutans, a main cavity bacterium, in a dish. It has not been tried in a mouth.

1 studiesNot covered. Essential oils are not safe to rinse with or swallow.

Studies, doses and limits

What the trials found

None.

Results

Growth stopped at 2.5% oil and bacteria were killed at 5.0% in the dish; biofilm and live cells fell by more than 75% at 5.0%.

Effect sizes as reported

Dish concentrations only. They are not a guide to use.

Why this rating

A dish test with one bacterium; no animal or human study. Dish strengths are not a safe guide for a mouth.

Form and dose studied

Not covered. Essential oils are not safe to rinse with or swallow.

Who was studied

None (bacteria).

Limits

Single species; no polymicrobial or living test.

Why researchers looked

Researchers look for cheap natural ways to prevent cavities.

Traditional use

Not covered.

Proposed mechanism Preliminary mechanism

The oil reduced growth and biofilm in the dish; genes linked to harm were turned up, which the authors read as a stress response.

A proposed mechanism does not show that the effect happens in people.

Bacteria in a dish; not a mouthwash. See the Safety tab.

22

Antioxidant and anti-inflammatory tests (lab; extracts, not the oil)

Very low certainty

A 2026 lab study analysed the chemistry of cardamom oil but ran its activity tests on water and ethanol extracts of the seeds. Those showed strong results in anti-inflammatory tests and moderate antioxidant activity. This is not a test of the oil.

1 studiesNot covered.

Studies, doses and limits

What the trials found

None.

Results

Oil: mostly monoterpenes, alpha-terpinyl acetate the main one. Extracts: low phenolic content, moderate antioxidant activity, strong anti-inflammatory test results, and effects on one starch-digesting enzyme.

Effect sizes as reported

Not given in the abstract.

Why this rating

Test tubes only, extracts rather than oil, and the authors call it preliminary.

Form and dose studied

Not covered.

Who was studied

None.

Limits

Not the oil; no living test.

Why researchers looked

Cardamom is a famous spice used in traditional medicine.

Traditional use

The authors describe cardamom as a spice also used in the traditional medicine of many cultures.

Proposed mechanism Preliminary mechanism

Test-tube assays only.

A proposed mechanism does not show that the effect happens in people.

Lab only.

7

Protection against seizures (mouse test)

Evidence against

In mice, cardamom oil gave only a negligible protection against induced seizures, and the oil and an extract both caused movement problems at higher amounts.

1 studiesNot covered.

Studies, doses and limits

What the trials found

None.

Results

The authors call the anticonvulsant effect negligible and note movement toxicity.

Effect sizes as reported

Not given in the abstract.

Why this rating

Animal study only; the effect was negligible and the oil caused movement problems.

Form and dose studied

Not covered.

Who was studied

Mice.

Limits

Animal study.

Why researchers looked

Compounds in cardamom were thought to have possible anticonvulsant activity.

Traditional use

Not covered.

Proposed mechanism Preliminary mechanism

Not established.

A proposed mechanism does not show that the effect happens in people.

The oil also caused movement problems in mice. See the Safety tab.

12

Connections to the rest of health

How Cardamom Oil connects to the rest of our health knowledge graph. Every link says what kind of connection it is. A safety link (for example to the liver) is a warning, not a benefit. A study that merely mentions a topic never creates a benefit link.

Explore every connection: goals, body systems, organs, symptoms, genes

A. Wellness goals

Connected toKind of connectionEvidence statusContextStudies
Digestive Support Low certainty Nausea during and after cesarean section (breathing cardamom oil): In one small Iranian trial of 70 mothers, those who breathed cardamom oil from a gauze pad had fewer nausea episodes, less retching and needed less anti-nausea medicine than mothers who breathed plain saline. Nausea in the recovery room (a four-oil blend that included cardamom): In a trial of 301 adults who felt sick after day surgery, breathing a blend of ginger, spearmint, peppermint and cardamom oils reduced nausea more than a saline pad. Cardamom was one of four oils, so this does not show that cardamom oil alone helps. 10 8
Digestive Support Not enough evidence Nausea with chemotherapy (inhaled aromatherapy review): A review of 11 studies found promising results for breathing oils directly from a pad. Three studies reduced nausea only, using chamomile, ginger or cardamom oil. Filling a room with the scent, and use in children, did not help. 23
Blood Pressure Support Not enough evidence Blood pressure (breathing oil vapours): A large Russian study tested vapours of 23 essential oils, including cardamom, on women with high blood pressure. The abstract names oils that lowered it, and oils that did not. Cardamom is on neither list. 25
Healthy Skin Very low certainty Slowing tooth-decay bacteria (lab dish only): In a 2026 lab study, cardamom oil was the strongest of twelve oils at stopping Streptococcus mutans, a main cavity bacterium, in a dish. It has not been tried in a mouth. 22
Inflammation Balance Very low certainty Antioxidant and anti-inflammatory tests (lab; extracts, not the oil): A 2026 lab study analysed the chemistry of cardamom oil but ran its activity tests on water and ethanol extracts of the seeds. Those showed strong results in anti-inflammatory tests and moderate antioxidant activity. This is not a test of the oil. 7
Calm Relaxation Evidence against Protection against seizures (mouse test): In mice, cardamom oil gave only a negligible protection against induced seizures, and the oil and an extract both caused movement problems at higher amounts. 12

B. Body systems

Connected toKind of connectionEvidence statusContextStudies
Digestive System Biological association Low certainty Studied for: Nausea during and after cesarean section (breathing cardamom oil) Studied for: Nausea in the recovery room (a four-oil blend that included cardamom) 10 8 23
Cardiovascular System Biological association Not enough evidence Studied for: Blood pressure (breathing oil vapours) 25
Immune System Biological association Very low certainty Studied for: Slowing tooth-decay bacteria (lab dish only) 22
Pain Inflammation Biological association Very low certainty Studied for: Antioxidant and anti-inflammatory tests (lab; extracts, not the oil) 7
Nervous System Biological association Evidence against Studied for: Protection against seizures (mouse test) 12

E. Health conditions

Connected toKind of connectionEvidence statusContextStudies
Contact dermatitis Adverse effect or risk Case report One allergy case and irritant powder reactions.
Preparation or compound: Cardamom seeds and powder (case report and patch tests); oil untested
14 13
Nausea Potential benefit Preliminary One small cesarean trial and one blend trial.
Preparation or compound: Cardamom oil inhaled; also in a four-oil blend
10 8
Childhood essential oil poisoning Documented risk Shows the risk with cineole-rich oils.
Preparation or compound: Eucalyptus and camphor oils (not cardamom)
4

I. Biomarkers

Connected toKind of connectionEvidence statusContextStudies
Nausea score (self-rated) Biological association Low certainty Measured in trials: decrease. A lab change is not the same as a health benefit. 10 8
Anti-nausea medicine used Biological association Low certainty Measured in trials: decrease. A lab change is not the same as a health benefit. 10 8
Blood pressure Biological association Not enough evidence Measured in trials: decrease. A lab change is not the same as a health benefit. 25

K. Biological pathways

Connected toKind of connectionEvidence statusContextStudies
Streptococcus mutans Preliminary mechanism In vitro Growth and biofilm reduced by the oil in a dish. 22

L. Active compounds

Connected toKind of connectionEvidence statusContextStudies
1,8-Cineole (eucalyptol) Biological association Lab / regulatory (other oil) Also the main compound of eucalyptus oil. The EU rule for young children and seizures is for eucalyptus oil; we apply it by caution only.
Preparation or compound: Seed oil
18 12 11 3
alpha-Terpinyl acetate Biological association Laboratory Main compound in several samples; no activity claimed here.
Preparation or compound: Seed oil
19 12 11 7
Linalyl acetate Biological association Laboratory No activity claimed.
Preparation or compound: Seed oil
20 11
Sabinene Biological association Laboratory No activity claimed.
Preparation or compound: Seed oil
21 12
Limonene and linalool Biological association Laboratory No activity claimed here. PubChem CIDs not looked up.
Preparation or compound: Seed oil
11 22

Each connection is stored with the ingredient, the connected record, the kind of connection, the evidence status, the supporting studies, the preparation or compound involved, and a review date (last reviewed October 25, 2026).

The evidence

The research centre for Cardamom Oil. Every record here was checked against PubMed or the publisher's page; we never list a study we have not verified.

Evidence by outcome

Bars show how many studies we found for each outcome, not how well it works. People are added up across trials only (reviews are not added, to avoid double counting).

How we rate evidence

High certainty

Several well-run trials or reviews agree; further research is unlikely to change the picture much.

Moderate certainty

Good trials point the same way, but some doubt remains.

Low certainty

Small, short or inconsistent trials. The finding could change with better research.

Very low certainty

Very little or very weak human data. Treat as a possibility only.

Mixed findings

Trials or reviews disagree with each other.

Not enough evidence

Not enough human research to say either way.

Evidence against

Good research found no benefit, or found harm.

We take the reviewers' own risk-of-bias and GRADE statements where they exist, and otherwise judge from study size, design, consistency, directness and whether a product matches what is sold. Many publications do not make evidence high. Method note: We read the abstracts of 15 PubMed papers and the Poison Control, Pet Poison Helpline, FDA, NCCIH and EMA pages, and checked the plant name in GBIF and compound names in PubChem. We did not find or read a LiverTox, LactMed or cardamom-oil regulator statement.

Study library: every study we checked 25
StudyDesignPeopleProduct, dose, lengthResult
Auti 2025
Effect of Cardamom Oil After Acute and Repeated Administration in Albino Wistar Rats.
Cureus · PMID 41487820 · DOI
Animal toxicity study (rats, OECD style)
rat
Female Wistar rats Cardamom oil given by mouth
essential oil Three amounts for 28 days and two single amounts (not repeated here) Single dose with 14 days of watching; 28 days repeated · vs Control group
At the highest single amount one animal died and two showed mild signs of toxicity, so the lethal dose was above that amount. In the 28-day test at three lower amounts there were no significant changes in weight, blood, kidney tests or organ tissue.
No harm seen in rats at the lower repeated amounts; one death at the highest single amount
Methods, limits and funding

Outcomes: Deaths, behaviour, body weight, blood and organ tests

Limitations: Rats given the oil by mouth; this does not tell us any safe amount for people.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Castillo 2023
Antioxidant Activity and GC-MS Profile of Cardamom (Elettaria cardamomum) Essential Oil Obtained by a Combined Extraction Method-Instant Controlled Pressure Drop Technology Coupled with Sonication.
Molecules · PMID 36770758 · DOI
Laboratory chemistry
none (chemistry)
Cardamom seeds Cardamom essential oil made with different pressure-drop and ultrasound treatments
seed n/a n/a · vs Untreated seeds
Yield rose with the new method. GC-MS found 28 compounds, with alpha-terpinyl acetate, geranyl oleate and oleic acid the most abundant in this sample, a different profile from other studies.
Profile depends on the method
Methods, limits and funding

Outcomes: Oil yield, antioxidant test, GC-MS profile

Limitations: Lab chemistry; shows how much oils differ by method.

Funding and conflicts: Not stated in the abstract.

Read: abstract

European Medicines Agency 2025
EMA: Eucalypti aetheroleum - herbal medicinal product (public summary)
n/a · Source
Regulator or reference page
n/a
n/a n/a
n/a n/a n/a · vs n/a
Page read 2026-10-25. This is about eucalyptus oil, a different oil that is rich in 1,8-cineole (the main compound of cardamom oil too). The EU herbal committee says these medicines must not be given to children under 30 months of age because of a risk of spasm of the larynx, and not to children with a history of seizures. Oral forms are for adults and adolescents from 12; inhaled, skin and bath forms from 4. Current monograph first published 28/02/2025. Not about cardamom.
Methods, limits and funding

Outcomes: Cineole-rich oil, children

Read: full-text

Flaman 2001
Unintentional exposure of young children to camphor and eucalyptus oils.
Paediatr Child Health · PMID 20084213 · DOI
Poison centre chart review and literature search
251
Children reported to a Toronto poison centre, Dec 1995 to Mar 1997
Swallowing of eucalyptus oil, camphorated oil and vapour products
eucalyptus and camphor (not cardamom) n/a n/a · vs n/a
251 children swallowed an essential oil product (50 eucalyptus oil). Common symptoms were cough and vomiting; two children had seizures and recovered. The literature search found 18 reports with vomiting, lethargy, coma and seizures, and one death. The authors say essential oils can be harmful, even life-threatening, if children swallow them.
Child poisonings with cineole-rich eucalyptus oil and camphor oils
Methods, limits and funding

Outcomes: Symptoms after swallowing

Limitations: About eucalyptus and camphor oils, not cardamom; shows what swallowing cineole-rich oils can do; older data.

Funding and conflicts: Not stated in the abstract.

Read: abstract

GBIF 2026
GBIF match: Elettaria cardamomum (L.) Maton
n/a · Source
Regulator or reference page
n/a
n/a n/a
n/a n/a n/a · vs n/a
API read 2026-10-25: exact match, status ACCEPTED, species key 2759871, family Zingiberaceae, order Zingiberales, kingdom Plantae.
Methods, limits and funding

Outcomes: Accepted name

Read: full-text

Heydarian 2024
Effect of cardamom consumption on inflammation and blood pressure in adults: A systematic review and meta-analysis of randomized clinical trials.
Food Sci Nutr · PMID 38268891 · DOI
Systematic review and meta analysis
Adults in 8 randomized trials of cardamom consumption Cardamom eaten as a food or supplement (not the essential oil)
spice/seed (not the oil) Varied Varied · vs Control
The authors report lower inflammation markers and lower blood pressure with cardamom, and say that because the number of studies is limited the results need cautious reading. This is about cardamom taken as food or supplement, not the essential oil.
Small average changes reported; does not apply to the oil
Methods, limits and funding

Outcomes: Inflammation markers and blood pressure

Limitations: Eight studies; findings between trials inconsistent per the authors; some units in the abstract look misprinted, so no figures are repeated here.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Hitl 2026
Queen of Spices, Cardamom (Elettaria cardamomum (L.) Maton, Zingiberaceae)-In Vitro Assessment of Biological Potential.
Molecules · PMID 42513114 · DOI
Laboratory study (in vitro)
in vitro
Cardamom seed oil and extracts in test tubes GC-MS of the essential oil; water and ethanol extracts for activity tests
seed n/a Lab assays · vs n/a
The oil was rich in monoterpenes with alpha-terpinyl acetate the main compound. Activity tests were done on the water and ethanol extracts, not the oil: moderate antioxidant activity, strong activity in anti-inflammatory tests, and effects on one starch-digesting enzyme. Microbe growth was reduced only at high concentrations. The authors call it preliminary.
Extract lab results; oil only analysed for chemistry
Methods, limits and funding

Outcomes: Oil chemistry; extract antioxidant, anti-inflammatory, sugar-enzyme and microbe tests

Limitations: Extracts, not oil, were tested for activity; test tubes only.

Funding and conflicts: Provincial research funding (Vojvodina) named in the record; not industry.

Read: abstract

Hunt 2013
Aromatherapy as treatment for postoperative nausea: a randomized trial.
Anesth Analg · PMID 22392970 · DOI
Randomized trial
301
Adults with nausea in the recovery room after ambulatory surgery at one US centre (303 enrolled, 301 analysed)
Inhaled gauze pad with (1) ginger oil, (2) a blend of ginger, spearmint, peppermint and cardamom oils, (3) isopropyl alcohol, or (4) saline placebo
essential oils (plant parts not stated in abstract) Not reported here Three deep breaths; nausea re-checked after 5 minutes · vs Saline gauze
Nausea fell more with the four-oil blend (P < 0.001) and with ginger (P = 0.002) than with saline, but not with alcohol. Fewer anti-nausea medicines were requested after ginger (P = 0.002) or the blend (P < 0.001) than saline.
Blend and ginger beat saline; alcohol did not
Methods, limits and funding

Outcomes: Nausea (0-3 scale) and anti-nausea medicines requested

Limitations: Cardamom was one of four oils in the blend, so its own effect cannot be separated; one centre; a scent is hard to hide; funding not stated in the abstract.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Khan 2014
Concentrated tea tree oil toxicosis in dogs and cats: 443 cases (2002-2012).
J Am Vet Med Assoc · PMID 24344857 · DOI
Retrospective case series
dog and cat
443
337 dogs and 106 cats exposed to 100% tea tree oil, US and Canada
100% tea tree oil on skin and/or by mouth
essential oil (tea tree, not cardamom) 0.1 to 85 mL used Signs within 2-12 hours, up to 72 hours · vs n/a
Serious signs (drooling, depression, weakness, wobbling, tremors) within hours and lasting up to 3 days; younger and lighter cats had a higher chance of major illness.
Shows cats can be badly affected by concentrated oil
Methods, limits and funding

Outcomes: Clinical signs and severity

Limitations: About tea tree oil, not cardamom; cited only to show the risk to cats from concentrated oils in general.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Khatiban 2022
Effect of Cardamom Inhalation Therapy on Intra-and Postoperative Nausea and Vomiting of Mothers Undergoing Spinal Anesthesia for Elective Cesarean Section.
J Perianesth Nurs · PMID 35581106 · DOI
Single blind randomized placebo controlled trial
70
Mothers having an elective cesarean section under spinal anesthesia, Hamadan, Iran (35 per group)
Cardamom essential oil on gauze in saline, inhaled from a plastic bag
essential oil (plant part not stated in abstract) Not reported here Inhaled at the first episode of nausea · vs Gauze in normal saline without oil
Nausea scores fell in both groups (placebo 25.28 +/- 32.38 and cardamom 13.14 +/- 19.96, P < .001); after allowing for starting nausea the fall was larger with cardamom. Nausea episodes 37.1% vs 65.7% (P = .006), retching 20% vs 45.7% (P = .028), anti-nausea medicine given 37.1% vs 65.7% (P = .009), cardamom vs placebo.
Fewer nausea episodes, less retching and less anti-nausea medicine with cardamom oil than saline
Methods, limits and funding

Outcomes: Nausea (100 mm visual scale), retching and nausea episodes, anti-nausea medicine use

Limitations: Small single-centre trial; the scent is hard to hide from participants; who was blinded is not detailed in the abstract; funding not stated in the abstract; the abstract gives no follow-up beyond the surgery period.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Marongiu 2004
Comparative analysis of the oil and supercritical CO2 extract of Elettaria cardamomum (L.) Maton.
J Agric Food Chem · PMID 15453700 · DOI
Laboratory chemistry
none (chemistry)
Cardamom seeds Cardamom seed oil by supercritical CO2 extraction, compared with steam-distilled oil and a hexane extract
seed n/a n/a · vs Hydrodistilled oil, hexane extract
CO2 oil: alpha-terpinyl acetate 42.3%, 1,8-cineole 21.4%, linalyl acetate 8.2%, limonene 5.6%, linalool 5.4%. The hydrodistilled oil showed no consistent difference; the hexane extract was very different (limonene 36.4%, 1,8-cineole 23.5%).
Composition depends on method
Methods, limits and funding

Outcomes: Oil yield and composition

Limitations: One sample set; shop oils may differ.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Masoumi-Ardakani 2016
Chemical Composition, Anticonvulsant Activity, and Toxicity of Essential Oil and Methanolic Extract of Elettaria cardamomum.
Planta Med · PMID 27433883 · DOI
Animal study (mice)
mouse
Mice with induced seizures Elettaria cardamomum essential oil and a methanol extract
essential oil Injected amounts (not repeated here) Single dose · vs Untreated
The oil contained 1,8-cineole (45.6%), alpha-terpinyl acetate (33.7%), sabinene (3.8%), terpinen-4-ol (2.4%) and myrcene (2.2%). The oil protected against seizures in two mouse models but the authors call the effect negligible. The oil and the extract both caused movement problems (rotarod) at the higher doses; no deaths at the doses tested.
Negligible anticonvulsant effect; movement toxicity in mice
Methods, limits and funding

Outcomes: Seizure protection, movement (rotarod) toxicity, deaths, oil composition

Limitations: Mouse study only; route and exact doses not stated in the abstract.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Meding 1993
Skin symptoms among workers in a spice factory.
Contact Dermatitis · PMID 8281784 · DOI
Survey and patch/prick testing
93
70 spice factory workers and 23 office workers, Sweden
Powders of spices including cardamom, paprika and white pepper (patch tests)
spice powders (not the oil) n/a Occupational · vs Office workers (questionnaire)
Half of factory workers reported skin symptoms, mostly with cinnamon. Irritant patch test reactions were seen to powders of cardamom, paprika and white pepper. The author says patch testing spices is difficult.
Irritant reactions to cardamom powder
Methods, limits and funding

Outcomes: Skin symptoms; patch and prick tests

Limitations: Powder, not oil; 1993; difficult to interpret.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Mobacken 1975
Allergic contact dermatitis from cardamom.
Contact Dermatitis · PMID 138507 · DOI
Case report
1
A confectioner with chronic hand dermatitis
Skin contact with dried cardamom seeds; patch tests with cardamom and terpene compounds from the seeds
seed (not the oil) n/a Occupational · vs n/a
Positive patch tests to cardamom and to certain terpenoid compounds in the seeds; the authors say it was the first such report they knew of and attribute it to terpenes in the seeds.
One allergic case
Methods, limits and funding

Outcomes: Patch test reactions

Limitations: One case, 1975; seeds, not oil.

Funding and conflicts: Not stated.

Read: abstract

National Center for Complementary and Integrative Health (NIH) 2020
NCCIH: Aromatherapy
n/a · Source
Regulator or reference page
n/a
n/a n/a
n/a n/a n/a · vs n/a
Page read 2026-10-25 (last updated January 2020). Essential oils are most often used by inhaling them or by applying a diluted form to the skin. The page says evidence for insomnia is lacking. It gives no cardamom-specific statement and no detailed safety section.
Methods, limits and funding

Outcomes: Aromatherapy overview

Read: full-text

Pet Poison Helpline 2026
Pet Poison Helpline: Essential Oils
n/a · Source
Regulator or reference page
n/a
n/a n/a
n/a n/a n/a · vs n/a
Page read 2026-10-25. Essential oil toxicosis can affect all species, but cats and birds are at the greatest risk. Swallowing carries the highest risk, then skin contact, then breathing the vapour. The page lists named oils (for example citrus, clove, eucalyptus, tea tree, pine, sage) and does not mention cardamom, which does not mean cardamom oil is safe for pets.
Methods, limits and funding

Outcomes: Pets and essential oils

Read: full-text

Poison Control (America's Poison Centers) 2026
Poison Control: Essential oils: Poisonous when misused
n/a · Source
Regulator or reference page
n/a
n/a n/a
n/a n/a n/a · vs n/a
Page read 2026-10-25. Pure oils are potent; diluting in a carrier oil is the best way to avoid a bad skin reaction; not all oils suit skin; do not use on damaged skin; stop and wash off if a rash appears. Many oils can cause rashes and some are poisonous if absorbed through the skin or swallowed. Breathing an oil into the lungs (for example while choking) can cause pneumonia. Children have thinner skin and may be more vulnerable. Sage oil and eucalyptus oil have caused seizures when swallowed. Oils may interact with medicines. Allergy is possible; any allergic reaction with trouble breathing is a medical emergency. Keep oils locked up, out of reach of children and pets. If someone swallows an essential oil, call the poison center (US 1-800-222-1222). The page does not mention cardamom and does not address pregnancy.
Methods, limits and funding

Outcomes: General essential-oil safety

Read: full-text

PubChem 2026
PubChem: 1,8-Cineole (CID 2758)
n/a · Source
Regulator or reference page
n/a
n/a n/a
n/a n/a n/a · vs n/a
API read 2026-10-25: name 1,8-Cineole, formula C10H18O, CID 2758.
Methods, limits and funding

Outcomes: Compound identity

Read: full-text

PubChem 2026
PubChem: alpha-Terpinyl acetate (CID 111037)
n/a · Source
Regulator or reference page
n/a
n/a n/a
n/a n/a n/a · vs n/a
API read 2026-10-25: alpha-Terpinyl acetate, formula C12H20O2, CID 111037.
Methods, limits and funding

Outcomes: Compound identity

Read: full-text

PubChem 2026
PubChem: Linalyl acetate (CID 8294)
n/a · Source
Regulator or reference page
n/a
n/a n/a
n/a n/a n/a · vs n/a
API read 2026-10-25: Linalyl Acetate, formula C12H20O2, CID 8294.
Methods, limits and funding

Outcomes: Compound identity

Read: full-text

PubChem 2026
PubChem: Sabinene (CID 18818)
n/a · Source
Regulator or reference page
n/a
n/a n/a
n/a n/a n/a · vs n/a
API read 2026-10-25: Sabinene, formula C10H16, CID 18818.
Methods, limits and funding

Outcomes: Compound identity

Read: full-text

Singh 2026
In vitro inhibition of Streptococcus mutans by cardamom essential oil.
Front Oral Health · PMID 42199993 · DOI
Laboratory study (in vitro)
bacteria
Streptococcus mutans bacteria in a dish Cardamom essential oil
essential oil MIC 2.5% and MBC 5.0% (v/v) in the dish Lab assays · vs Twelve other essential oils
The lowest strength that stopped growth was 2.5% and killed the bacteria 5.0%. At 5.0%, biofilm and cell viability fell by more than 75% while virulence genes were turned up, which the authors read as a stress response. Of twelve oils tested, cardamom oil was the strongest. The authors call for tests in living models.
Strongest of 12 oils in a dish
Methods, limits and funding

Outcomes: Growth, biofilm, cell viability, virulence genes

Limitations: Bacteria in a dish only; not a mouthwash and not tested in people.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Toniolo 2021
Effectiveness of Inhaled Aromatherapy on Chemotherapy-Induced Nausea and Vomiting: A Systematic Review.
J Altern Complement Med · PMID 34283916 · DOI
Systematic review
11 studies (9 in adults, 2 in children) of inhaled aromatherapy for chemotherapy nausea Inhaled aromatherapy (peppermint, ginger, chamomile or cardamom oils, among others)
essential oils Varied Varied · vs Standard care
Seven of nine adult studies showed significant results. Three reduced nausea only, with chamomile, ginger or cardamom oil. Diffusing into the room and use in children showed no benefit. The authors say small samples and the wide variety of oils and methods make it impossible to generalise.
Promising but not generalisable, per the authors
Methods, limits and funding

Outcomes: Nausea and vomiting with chemotherapy

Limitations: The abstract does not say which study used cardamom or how large it was; mostly women with gynecologic cancers; methodological limits and small samples, per the authors.

Funding and conflicts: Not stated in the abstract.

Read: abstract

U.S. Food and Drug Administration 2023
FDA: Aromatherapy
n/a · Source
Regulator or reference page
n/a
n/a n/a
n/a n/a n/a · vs n/a
Page read 2026-10-25 (content current as of 09/08/2023). Whether an aromatherapy product is a cosmetic or a drug depends on its intended use and claims. Products with therapeutic claims (for example relieving pain, treating anxiety, aiding sleep) are drugs and need approval. 'Natural' does not mean safe: plant materials can be toxic, irritating or allergenic on skin; the page gives cumin oil (can blister skin) and some citrus oils (harm on sun-exposed skin) as examples. The page does not mention cardamom.
Methods, limits and funding

Outcomes: Regulatory status of aromatherapy

Read: full-text

Yarosh 2023
[Impact of essential oil vapors inhalation on blood pressure in patients with hypertension].
Vopr Kurortol Fizioter Lech Fiz Kult · PMID 37141519 · DOI
Comparative study with control group (design details limited in abstract)
849
Women aged 55-89 with hypertension, Russia
Inhaled vapours of 23 essential oils, including cardamom, with a relaxation procedure
essential oils 1 mg/m3 in air 10- or 20-minute sessions · vs Relaxation procedure alone
The abstract names 11 oils with a blood-pressure-lowering effect and a second list of 10 with none. Cardamom was among the oils tested but is in neither list, so the abstract gives no cardamom result.
No cardamom-specific result stated
Methods, limits and funding

Outcomes: Blood pressure, heart rate

Limitations: Abstract does not report cardamom; design (randomization, blinding) not described in the abstract; Russian-language paper, English abstract read.

Funding and conflicts: Not stated in the abstract.

Read: abstract

What we do not know yet

  • What the evidence supports: the human results are low or insufficient, from two small nausea trials and a review; lab findings are very-low.
  • Only one trial tested cardamom oil alone, and it was small.
  • No poisoning, patch-test, pet, asthma or seizure source for cardamom oil itself.
  • The child and seizure cautions come from a similar oil (eucalyptus), not from cardamom oil.
  • No study of the oil in pregnancy, breastfeeding or children.
  • No verified dilution figure; we give none.

How new research is added

New studies are found by a saved PubMed search and are placed in a review queue. A person reads each one before it is added.

Lab markers

What changed in blood or saliva tests during trials. A changed number is not the same as feeling or being healthier, and we give no "normal ranges".

Other 3

●

Nausea score (self-rated)

Decrease in trials

A rating of how sick the person feels, on a 100 mm line or a 0 to 3 scale.

Low certainty
Results and what it means

Why it was measured

The main outcome in both surgery trials.

Statistical vs. clinical meaning

A feeling score, not a lab test; a scent is hard to hide from participants.

Safety implication

A lower score does not show the oil is safe for everyone.

StudyResultPeopleProduct
10Scores fell in both groups; the fall was larger with cardamom oil than with saline after allowing for the starting level.
8Nausea fell more with the four-oil blend than with saline (P < 0.001).

10 8

●

Anti-nausea medicine used

Decrease in trials

How many people needed or asked for an anti-nausea drug.

Low certainty
Results and what it means

Why it was measured

A practical sign that nausea was still a problem.

Statistical vs. clinical meaning

Staff may have known what the patient was given, which can affect when drugs are offered.

Safety implication

None found in the abstracts.

StudyResultPeopleProduct
1037.1% with cardamom oil vs 65.7% with saline (P = .009).
8Fewer requests after the blend or ginger than saline (P < 0.001 and P = 0.002).

10 8

●

Blood pressure

Decrease in trials

Pressure of blood in the arteries, measured in mmHg.

Not enough evidence
Results and what it means

Why it was measured

The outcome of the inhaled-vapour study.

Statistical vs. clinical meaning

We make no claim for cardamom oil.

Safety implication

Anyone on blood pressure medicine should ask a doctor before using essential oils.

StudyResultPeopleProduct
25No cardamom-specific result is stated in the abstract.

25

Safety

What studies and official sources say about side effects, medicines and who should check first. Each point shows what kind of evidence it comes from.

Main points to know 5
  • Do not swallow cardamom essential oil.. Poison Control says many essential oils are poisonous if swallowed, that breathing an oil into the lungs while choking can cause pneumonia, and that sage and eucalyptus oils have caused seizures when swallowed. A Toronto poison-centre review of eucalyptus and camphor oils, which are also rich in 1,8-cineole, found cough, vomiting, seizures in two children and, in the literature, one death. We found no poisoning report for cardamom oil itself, so its risk is unmeasured, not shown to be small. Keep bottles locked away from children and pets. Regulatory 17 4
  • Do not put it on skin undiluted.. Poison Control says pure oils are potent and that diluting in a carrier oil is the best way to avoid a bad skin reaction, and not to use oils on damaged skin. Cardamom itself has caused allergic contact dermatitis in a case report (seeds) and irritant patch-test reactions to the powder in a spice factory study. No skin study of cardamom oil was found. We give no dilution figure because we could not verify one. Regulatory 17 14 13
  • Keep it off the faces of babies and young children.. Cardamom oil is about a fifth to a half 1,8-cineole in the samples tested. For a cineole-rich oil, eucalyptus, the EU herbal committee says medicines must not be given to children under 30 months because of a risk of spasm of the larynx, and not to children with a history of seizures. That is a different oil and a medicine rule, not a cardamom-oil rule, but the main compound is shared. We advise keeping cardamom oil away from young children's faces and noses and from children who have had seizures. Regulatory 3 12 11
  • Pets, especially cats and birds, are at risk.. Pet Poison Helpline says essential oil poisoning can affect all species, but cats and birds are at the greatest risk, and swallowing is the riskiest route. Cardamom is not named on its list, which does not make it safe. A US case series of concentrated tea tree oil, a different oil, found serious signs in dogs and cats within hours. Regulatory 16 9
  • Pregnancy: no cardamom-oil study was found.. We found no study of cardamom oil in pregnancy or breastfeeding, and Poison Control does not address pregnancy. We advise asking a midwife or doctor before using it. The nausea trial in mothers was done at a cesarean section, not in pregnancy. Theoretical 17 10
Side effects 6
EffectHow oftenSeverity and recoveryEvidence
Allergic contact dermatitis from cardamom
One 1975 case in a confectioner, patch tests positive to cardamom and its terpenes. Seeds, not oil.
Not establishedHand eczema in one worker
Not stated
Case_report 14
Skin irritation from cardamom powder
Swedish spice-factory study; powder not oil; the author says spice patch tests are hard to interpret.
Not establishedIrritant patch-test reactions
Not stated
Observational 13
Poisoning if swallowed
Evidence is for other cineole-rich and camphor oils, not cardamom.
Not establishedCough, vomiting, seizures reported with eucalyptus and camphor oils in children
Most recovered; one death in the literature (other oils)
Observational 4 17
Movement problems and sedation-like effects in mice
Mouse study; no deaths at the doses tested.
Not establishedMovement toxicity (rotarod) at higher amounts
Not stated
Animal research 12
Deaths at a very high swallowed amount in rats
In rats, no harm seen at lower repeated amounts for 28 days. This is not a safe amount for people.
Not establishedOne of three rats died at the highest single amount tested
n/a
Animal research 1
Nausea trial side effects
Neither abstract reports adverse effects.
Not establishedNot described in the abstracts
Not stated
Controlled trial 10 8
Liver

We found no liver injury report for cardamom essential oil and no LiverTox record was read, so none is claimed. In the rat toxicity study, liver tests did not change at the lower amounts given for 28 days. 1

How often. Not established.

Monitoring. Not applicable.

This is a safety connection. It is not evidence that Cardamom Oil supports liver health.

Medicines and supplements 3
WithWhy it mattersImportanceEvidenceWhat to do
Prescription and over-the-counter medicines
medicines in general
Poison Control says essential oils may interact with medications. No cardamom-oil interaction was found in the sources read.Unknown for cardamom oil.Theoretical Not enough evidence 17If you take regular medicines, ask a pharmacist before using any essential oil product.
Medicines for epilepsy
anti-seizure and nerve-active medicines
1,8-cineole-rich oils have been linked to seizures in children when swallowed, and cardamom oil caused movement problems in mice. No human interaction study was found.Not known; caution only.Theoretical Not enough evidence 17 12People with epilepsy should ask their doctor before using any essential oil.
Blood pressure medicines
blood pressure medicines
A study of inhaled vapours looked at blood pressure, but the abstract gives no cardamom result.No interaction shown.Theoretical Not enough evidence 25Mention essential oil use to your doctor if you are treated for high blood pressure.
Who should check first 6
SituationAdviceEvidence
Swallowing the oil, especially by or near childrenDo not swallow. If a child or pet may have swallowed any essential oil, call poison control (US: 1-800-222-1222) or your emergency number.Regulatory 17 4
Babies and young children (face and nose)Avoid. A cineole-rich oil carries an EU warning for children under 30 months because of laryngeal spasm risk.Regulatory 3
A history of seizuresAvoid unless a doctor says otherwise: cineole-rich oils carry an EU warning for children with seizure history, and the mouse study showed movement toxicity.Regulatory 3 12
Known allergy to cardamom or to essential oilsAvoid. Stop and wash off if a rash appears.Case_report 14 17
Damaged or broken skinDo not use essential oils on damaged skin (Poison Control).Regulatory 17
Pets in the home, especially cats and birdsKeep oils locked up and do not use them on pets.Regulatory 16
Overdose, product quality and regulators

Summary. No poisoning case and no lethal amount for people were found. In rats, the highest single amount killed one of three animals and the lower repeated amounts for 28 days caused no significant changes. In mice, the oil caused movement problems.

Amounts. No safe amount is established, and this page gives none.

Onset and course. Not described for cardamom oil.

Repeated use. Rat study of 28 days showed no significant changes at three lower amounts. Not studied in people.

Animal data. Rat: one death at the highest single oral amount and mild signs in the other two; no significant change in weight, blood, kidney tests or organ tissue after 28 days at lower amounts. Mouse: movement toxicity at higher amounts; no deaths at the doses tested.

Toxic parts. The oil is the concentrated volatile part of the seed. Main compounds were 1,8-cineole and alpha-terpinyl acetate; neither was tested alone here.

Not read. No LiverTox, LactMed, patch-test rate for the oil, pet case, asthma or sun-sensitivity source was found for cardamom oil. Absence is not proof of safety.

Essential oils are not tightly regulated, and what is in the bottle can differ from the label. Cardamom oil also differs by how it is made.

Unknown species, strength and contaminants. Poison Control says it can be hard to know what species, concentration or contaminants are in an essential oil bottle. 17

Composition varies by method and sample. 1,8-cineole was 45.6% of the oil in a mouse study but 21.4% in a CO2 extract; alpha-terpinyl acetate was 33.7% and 42.3%. A 2023 sample made with a new method had geranyl oleate and oleic acid among its main compounds. A result for one oil does not carry over to another. 12 11 2

Not a drug claim. FDA says aromatherapy products with therapeutic claims are drugs and that natural does not mean safe. 24

BodyActionDate
FDA (US) (United States)Aromatherapy products are regulated as cosmetics or drugs depending on intended use; products making therapeutic claims are drugs. Natural does not mean safe; plant oils can be toxic, irritating or allergenic. No cardamom-specific statement on that page. source2023-09-08
Poison Control (America's Poison Centers) (United States)Misused essential oils can cause serious poisoning; dilute for skin, do not use on damaged skin, keep locked away; call 1-800-222-1222 if swallowed. source2026
EMA Committee on Herbal Medicinal Products (HMPC), eucalyptus oil monograph (a different, cineole-rich oil) (European Union)Medicines must not be given to children under 30 months (laryngeal spasm risk) or to children with a seizure history. Not a cardamom statement. source2025-02-28
NCCIH (NIH) (United States)Aromatherapy overview; says oils are most often inhaled or applied diluted to skin. No cardamom statement. source2020-01
When to get medical help
  • If a child or pet may have swallowed any essential oil, call poison control straight away (US: 1-800-222-1222) or your local emergency number. Do not wait for symptoms.
  • Trouble breathing, a swollen face or throat, or hives after using any essential oil: treat as an emergency (Poison Control).
  • A rash or burning on the skin: stop, and gently wash the oil off with soap and water (Poison Control).
  • A seizure, or a child struggling to breathe after contact with an essential oil: get emergency help.
  • Pregnant and unwell after using an oil: contact your midwife or doctor.

Stop using the product and contact a clinician or emergency service. In the US, Poison Control is 1-800-222-1222.

General information only, not medical advice. Ask a clinician or pharmacist before use, especially with medicines, in pregnancy or with a health condition. See the Natural Remedy Safety guide.

Frequently asked questions

Is cardamom oil safe to swallow?

No. We do not advise swallowing essential oil. Poison Control says many essential oils are poisonous if swallowed and that sage and eucalyptus oils have caused seizures that way. We found no poisoning report for cardamom oil, so the risk is unmeasured, not shown to be small. If a child or pet may have swallowed any essential oil, call poison control (US: 1-800-222-1222) or your emergency number.

17 4

Can cardamom oil go on the skin?

Be careful. Poison Control says pure oils are potent, diluting in a carrier oil is the best way to avoid a bad reaction, and oils should not go on damaged skin. Cardamom seeds caused allergic hand eczema in a case report. We give no dilution figure because we could not verify one. If you get a rash, stop and wash the oil off.

17 14 13

Is cardamom oil safe for babies and young children?

Keep it away. Cardamom oil is rich in 1,8-cineole, also the main part of eucalyptus oil. For eucalyptus medicines, the EU herbal committee says not under 30 months because of a risk of throat spasm, and not for children with seizures. This is a rule for another oil, so we apply it as a caution. We found no safety study of cardamom oil in children.

3 12 11

Is cardamom oil safe in pregnancy?

We found no study of cardamom oil in pregnancy or breastfeeding. We advise asking a midwife or doctor before using it. The nausea trial was in mothers having a cesarean section, not in pregnancy.

17 10

Is cardamom oil safe for cats and dogs?

Be careful. Pet Poison Helpline says essential oil poisoning can affect all species, but cats and birds are at greatest risk. Cardamom is not named on its list, which does not mean it is safe. Keep oils locked away and do not put them on pets.

16 9

Does cardamom oil help with nausea?

Maybe a little, but the evidence is low. One small trial of 70 mothers found less nausea and retching with cardamom oil than with saline. A larger trial used a four-oil blend that included cardamom, so cardamom's own part is unknown. A review calls results promising but says they cannot be generalised.

10 8 23

Does cardamom oil lower blood pressure?

We cannot say. A study of vapours of 23 oils on women with high blood pressure tested cardamom, but its abstract gives no cardamom result. Reports of lower blood pressure with cardamom are about eating the spice, not the oil.

25 6

Can cardamom oil fight tooth decay?

Only in a dish so far. In a 2026 lab study it was the strongest of twelve oils against a cavity bacterium. It has not been tested in a mouth, and essential oils are not safe to swallow, so this is not a mouthwash.

22

Is cardamom oil the same as cardamom spice?

No. The oil is the concentrated volatile part of the seed. Studies of cardamom eaten as food or supplement do not tell us about the oil, and the reverse. Black cardamom is a different plant again.

6 7

What is in cardamom oil?

Mainly 1,8-cineole and alpha-terpinyl acetate, with linalyl acetate, limonene, linalool and sabinene in smaller amounts. The proportions differ with how the oil is made.

12 11 2

Does cardamom oil interact with medicines?

Poison Control says essential oils may interact with medicines. We found no cardamom-specific interaction, which is not proof of none. If you take regular medicines, or have epilepsy or high blood pressure, ask a pharmacist or doctor.

17 12

Is cardamom oil a treatment for anything?

No. The research is too small to call it a treatment, and the FDA says aromatherapy products with therapeutic claims are drugs. Natural does not mean safe. Talk to a doctor about nausea or other health problems.

24 10

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Editorial transparency
Written by
AlternativeMed editorial team. Research compiled with AI assistance, then checked against PubMed records.
Medical review
None. This page has not been reviewed by a physician or pharmacist.
First published
2026-10-25
Last substantive update
2026-10-25
How we research
We read the abstracts of 15 PubMed papers and the Poison Control, Pet Poison Helpline, FDA, NCCIH and EMA pages, and checked the plant name in GBIF and compound names in PubChem. We did not find or read a LiverTox, LactMed or cardamom-oil regulator statement.
How we rate evidence
See "How we rate evidence" in the Evidence tab.
Independence
No product is promoted on this page. No affiliate links are shown.
Sources 25

Each source was opened and checked. Where we read only the abstract, it says so. The small numbers in the text point here.

  1. Auti S, Kulkarni YA. Effect of Cardamom Oil After Acute and Repeated Administration in Albino Wistar Rats.. Cureus. 2025. PMID 41487820. DOI 10.7759/cureus.98295. (abstract)
  2. Castillo NE, Torres NET, Teresa-Martinez GD, Alonzo-Macias M, Tellez-Perez C, Rodriguez-Rodriguez J, Sosa-Hernandez JE, Parra-Saldivar R, Melchor-Martinez EM, Cardador-Martinez A. Antioxidant Activity and GC-MS Profile of Cardamom (Elettaria cardamomum) Essential Oil Obtained by a Combined Extraction Method-Instant Controlled Pressure Drop Technology Coupled with Sonication.. Molecules. 2023. PMID 36770758. DOI 10.3390/molecules28031093. (abstract)
  3. European Medicines Agency. EMA: Eucalypti aetheroleum - herbal medicinal product (public summary). n/a. 2025. (full-text)
  4. Flaman Z, Pellechia-Clarke S, Bailey B, McGuigan M. Unintentional exposure of young children to camphor and eucalyptus oils.. Paediatr Child Health. 2001. PMID 20084213. DOI 10.1093/pch/6.2.80. (abstract)
  5. GBIF. GBIF match: Elettaria cardamomum (L.) Maton. n/a. 2026. (full-text)
  6. Heydarian A, Tahvilian N, Shahinfar H, Abbas-Hashemi SA, Daryabeygi-Khotbehsara R, Aryaeian N. Effect of cardamom consumption on inflammation and blood pressure in adults: A systematic review and meta-analysis of randomized clinical trials.. Food Sci Nutr. 2024. PMID 38268891. DOI 10.1002/fsn3.3738. (abstract)
  7. Hitl M, Radovanovic K, Urumovic K, Prpa B, Kladar N. Queen of Spices, Cardamom (Elettaria cardamomum (L.) Maton, Zingiberaceae)-In Vitro Assessment of Biological Potential.. Molecules. 2026. PMID 42513114. DOI 10.3390/molecules31142430. (abstract)
  8. Hunt R, Dienemann J, Norton HJ, Hartley W, Hudgens A, Stern T, Divine G. Aromatherapy as treatment for postoperative nausea: a randomized trial.. Anesth Analg. 2013. PMID 22392970. DOI 10.1213/ANE.0b013e31824a0b1c. (abstract)
  9. Khan SA, McLean MK, Slater MR. Concentrated tea tree oil toxicosis in dogs and cats: 443 cases (2002-2012).. J Am Vet Med Assoc. 2014. PMID 24344857. DOI 10.2460/javma.244.1.95. (abstract)
  10. Khatiban M, Mirzaie M, Fazeli A, Tapak L, Khalili Z. Effect of Cardamom Inhalation Therapy on Intra-and Postoperative Nausea and Vomiting of Mothers Undergoing Spinal Anesthesia for Elective Cesarean Section.. J Perianesth Nurs. 2022. PMID 35581106. DOI 10.1016/j.jopan.2021.09.008. (abstract)
  11. Marongiu B, Piras A, Porcedda S. Comparative analysis of the oil and supercritical CO2 extract of Elettaria cardamomum (L.) Maton.. J Agric Food Chem. 2004. PMID 15453700. DOI 10.1021/jf034819i. (abstract)
  12. Masoumi-Ardakani Y, Mandegary A, Esmaeilpour K, Najafipour H, Sharififar F, Pakravanan M, Ghazvini H. Chemical Composition, Anticonvulsant Activity, and Toxicity of Essential Oil and Methanolic Extract of Elettaria cardamomum.. Planta Med. 2016. PMID 27433883. DOI 10.1055/s-0042-106971. (abstract)
  13. Meding B. Skin symptoms among workers in a spice factory.. Contact Dermatitis. 1993. PMID 8281784. DOI 10.1111/j.1600-0536.1993.tb03538.x. (abstract)
  14. Mobacken H, Fregert S. Allergic contact dermatitis from cardamom.. Contact Dermatitis. 1975. PMID 138507. DOI 10.1111/j.1600-0536.1975.tb05361.x. (abstract)
  15. National Center for Complementary and Integrative Health (NIH). NCCIH: Aromatherapy. n/a. 2020. (full-text)
  16. Pet Poison Helpline. Pet Poison Helpline: Essential Oils. n/a. 2026. (full-text)
  17. Poison Control (America's Poison Centers). Poison Control: Essential oils: Poisonous when misused. n/a. 2026. (full-text)
  18. PubChem. PubChem: 1,8-Cineole (CID 2758). n/a. 2026. (full-text)
  19. PubChem. PubChem: alpha-Terpinyl acetate (CID 111037). n/a. 2026. (full-text)
  20. PubChem. PubChem: Linalyl acetate (CID 8294). n/a. 2026. (full-text)
  21. PubChem. PubChem: Sabinene (CID 18818). n/a. 2026. (full-text)
  22. Singh NJ, Kezer G, Horn MA, Hillebrand S, Esatbeyoglu T. In vitro inhibition of Streptococcus mutans by cardamom essential oil.. Front Oral Health. 2026. PMID 42199993. DOI 10.3389/froh.2026.1796712. (abstract)
  23. Toniolo J, Delaide V, Beloni P. Effectiveness of Inhaled Aromatherapy on Chemotherapy-Induced Nausea and Vomiting: A Systematic Review.. J Altern Complement Med. 2021. PMID 34283916. DOI 10.1089/acm.2021.0067. (abstract)
  24. U.S. Food and Drug Administration. FDA: Aromatherapy. n/a. 2023. (full-text)
  25. Yarosh AM, Tonkovtseva VV, Grigoriev PE, Batura IA. [Impact of essential oil vapors inhalation on blood pressure in patients with hypertension].. Vopr Kurortol Fizioter Lech Fiz Kult. 2023. PMID 37141519. DOI 10.17116/kurort202310002122. (abstract)
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.