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Herb Research & Evidence

How much research exists on herbs, what a PubMed count does and does not show, how to read herb studies, and the gaps. Includes an evidence snapshot for 26 herbs.

Content last updated . This page has not been medically reviewed.

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Evidence snapshot

Counts of PubMed records that mention each herb. A count shows how much has been published, not whether an herb works. Searches match title or abstract words, so they include lab, animal and food research, and curcumin and silymarin are counted with their plants.
HerbRecords tagged as randomized controlled trialsRecords tagged as any clinical trialAll PubMed records that mention itCheck it yourself
Turmeric / curcumin59770531,898PubMed search
Elderberry18291,372PubMed search
Milk thistle1472024,909PubMed search
Ginger2773126,632PubMed search
Green tea54666920,779PubMed search
Garlic2232819,502PubMed search
Echinacea69931,546PubMed search
Chamomile1011161,843PubMed search
Saw palmetto85103669PubMed search
Valerian6277966PubMed search
Ginkgo3374135,886PubMed search
St. John's wort1672444,195PubMed search
Aloe vera1281482,944PubMed search
Cranberry1551822,233PubMed search
Black cohosh4962705PubMed search
Passionflower1921287PubMed search
Lemon balm5156898PubMed search
Cinnamon1101295,992PubMed search
Fenugreek50592,051PubMed search
Feverfew914442PubMed search
Hawthorn47531,868PubMed search
Boswellia / frankincense871011,358PubMed search
Kava3842884PubMed search
Nettle26331,001PubMed search
Hibiscus41522,209PubMed search
Moringa34403,315PubMed search

Counted 2026-10-22 using NCBI E-utilities. Counts include studies of extracts, blends and non-health topics, and a trial can find no effect. A higher count means more human research has been indexed, not that something works.

What the numbers can mislead about

  • Turmeric has hundreds of randomized trials in PubMed, yet NIH says it does not know enough to conclude turmeric or curcumin helps any health purpose. [1]
  • Ginkgo has many trials, and NIH says it has not been shown effective for any condition studied. [2]
  • Elderberry has far fewer trials, and NIH calls the evidence preliminary. [3]

How to read herb studies

  • Which herb, part and product? Extracts differ from foods and teas. [4]
  • Human or lab? Laboratory findings do not show what an herb does in people.
  • How many people, how long? NIH often notes small, short or poor-quality studies.
  • Negative and mixed results count. Saw palmetto, ginkgo for dementia and echinacea for colds are examples of studies that did not support popular claims. [5]
  • Who funded it? Check for independent funding.

Gaps

Long-term safety, interactions, best forms and doses are poorly studied for most herbs. See Safety.

References

  1. National Center for Complementary and Integrative Health (NIH). Turmeric: Usefulness and Safety. Page last updated April 2025.
  2. National Center for Complementary and Integrative Health (NIH). Ginkgo: Usefulness and Safety. Page last updated February 2025.
  3. National Center for Complementary and Integrative Health (NIH). Elderberry: Usefulness and Safety. Page last updated November 2024.
  4. National Center for Complementary and Integrative Health (NIH). Ginger: Usefulness and Safety. Page last updated February 2025.
  5. National Center for Complementary and Integrative Health (NIH). Using Dietary Supplements Wisely. Page last updated January 2019.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.