Herb Research & Evidence
How much research exists on herbs, what a PubMed count does and does not show, how to read herb studies, and the gaps. Includes an evidence snapshot for 26 herbs.
Content last updated . This page has not been medically reviewed.
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Evidence snapshot
Counts of PubMed records that mention each herb. A count shows how much has been published, not whether an herb works. Searches match title or abstract words, so they include lab, animal and food research, and curcumin and silymarin are counted with their plants.| Herb | Records tagged as randomized controlled trials | Records tagged as any clinical trial | All PubMed records that mention it | Check it yourself |
|---|---|---|---|---|
| Turmeric / curcumin | 597 | 705 | 31,898 | PubMed search |
| Elderberry | 18 | 29 | 1,372 | PubMed search |
| Milk thistle | 147 | 202 | 4,909 | PubMed search |
| Ginger | 277 | 312 | 6,632 | PubMed search |
| Green tea | 546 | 669 | 20,779 | PubMed search |
| Garlic | 223 | 281 | 9,502 | PubMed search |
| Echinacea | 69 | 93 | 1,546 | PubMed search |
| Chamomile | 101 | 116 | 1,843 | PubMed search |
| Saw palmetto | 85 | 103 | 669 | PubMed search |
| Valerian | 62 | 77 | 966 | PubMed search |
| Ginkgo | 337 | 413 | 5,886 | PubMed search |
| St. John's wort | 167 | 244 | 4,195 | PubMed search |
| Aloe vera | 128 | 148 | 2,944 | PubMed search |
| Cranberry | 155 | 182 | 2,233 | PubMed search |
| Black cohosh | 49 | 62 | 705 | PubMed search |
| Passionflower | 19 | 21 | 287 | PubMed search |
| Lemon balm | 51 | 56 | 898 | PubMed search |
| Cinnamon | 110 | 129 | 5,992 | PubMed search |
| Fenugreek | 50 | 59 | 2,051 | PubMed search |
| Feverfew | 9 | 14 | 442 | PubMed search |
| Hawthorn | 47 | 53 | 1,868 | PubMed search |
| Boswellia / frankincense | 87 | 101 | 1,358 | PubMed search |
| Kava | 38 | 42 | 884 | PubMed search |
| Nettle | 26 | 33 | 1,001 | PubMed search |
| Hibiscus | 41 | 52 | 2,209 | PubMed search |
| Moringa | 34 | 40 | 3,315 | PubMed search |
Counted 2026-10-22 using NCBI E-utilities. Counts include studies of extracts, blends and non-health topics, and a trial can find no effect. A higher count means more human research has been indexed, not that something works.
What the numbers can mislead about
- Turmeric has hundreds of randomized trials in PubMed, yet NIH says it does not know enough to conclude turmeric or curcumin helps any health purpose. [1]
- Ginkgo has many trials, and NIH says it has not been shown effective for any condition studied. [2]
- Elderberry has far fewer trials, and NIH calls the evidence preliminary. [3]
How to read herb studies
- Which herb, part and product? Extracts differ from foods and teas. [4]
- Human or lab? Laboratory findings do not show what an herb does in people.
- How many people, how long? NIH often notes small, short or poor-quality studies.
- Negative and mixed results count. Saw palmetto, ginkgo for dementia and echinacea for colds are examples of studies that did not support popular claims. [5]
- Who funded it? Check for independent funding.
Gaps
Long-term safety, interactions, best forms and doses are poorly studied for most herbs. See Safety.References
- National Center for Complementary and Integrative Health (NIH). Turmeric: Usefulness and Safety. Page last updated April 2025.
- National Center for Complementary and Integrative Health (NIH). Ginkgo: Usefulness and Safety. Page last updated February 2025.
- National Center for Complementary and Integrative Health (NIH). Elderberry: Usefulness and Safety. Page last updated November 2024.
- National Center for Complementary and Integrative Health (NIH). Ginger: Usefulness and Safety. Page last updated February 2025.
- National Center for Complementary and Integrative Health (NIH). Using Dietary Supplements Wisely. Page last updated January 2019.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.