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Lemongrass stalks and leaves, the plant the oil is distilled from
Lemongrass (Cymbopogon); the oil is distilled from the leaves.

Essential Oils & Aromatherapy · Essential oil

Lemongrass Oil

Cymbopogon citratus and Cymbopogon flexuosus · also called Lemongrass essential oil, West Indian lemongrass oil, East Indian lemongrass oil, citral-rich oil

Lemongrass oil is the strong, lemony oil distilled from the leaves of lemongrass grasses. It is used as a scent, in hair and mouth products and in some insect repellents. The research is small: a few trials on scent and anxiety, dandruff and mouth rinses, with limited and mixed results. The main caution: the oil is a known skin allergen, it should not be swallowed, and it can harm pets.

General information, not medical advice. Last substantive update · Not medically reviewed. A named clinician has not signed off on this page. How this page is made

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About Lemongrass Oil

Lemongrass oil is a strongly scented oil with a few small studies behind its uses. Safety comes first: it is a known skin allergen, it should not be swallowed, and essential oils can harm pets, especially cats and birds. The evidence for benefit is limited, mostly from small trials of made products rather than plain oil.

What lemongrass oil is

Lemongrass oil is distilled from the leaves of lemongrass grasses. Two species are used: Cymbopogon citratus (West Indian lemongrass) and Cymbopogon flexuosus (East Indian lemongrass). Several trials used C. flexuosus, and a result for one species or product does not carry over to another.

Citral is the main compound, about 65 to 85% of the oil by one review. Citral is also the compound behind the skin allergy and it breaks down in air. Citronella grasses are different species with different oil.

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What people use it for, and how strong the evidence is

For anxiety, two small trials found lower scores while people breathed the oil during dental treatment or a lab stress test. Neither used a comparison scent that hid the oil from the person, so expectation could not be separated from the oil. Certainty is very low.

For dandruff, one small Thai trial of a hair tonic with the oil (C. flexuosus) reported about half the dandruff score or less after two weeks. For a yeast skin infection, a pilot of an oil shampoo and cream cleared about 60% of those who finished, and the standard drug did better. For mouth care, small trials of mouth rinses had mixed results. Certainty is low to very low.

For mosquitoes, a 2026 review said oil-based repellents usually protect two to four hours, less than DEET, while a 2002 test found most botanical repellents protected under 20 minutes. The CDC recommends registered repellents where mosquito-borne illness is a risk.

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The research in one view

Most trials are small, short and run by regional groups. Several used made products with other ingredients, not plain oil. Animal and cell findings (calming effects, inflammation, blood sugar) have not been tested in people. A single 2026 report on a nicotine inhaler has surprising results and no repeat.

Nothing here shows that lemongrass oil treats a disease.

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Oil, tea and herb are different things

Lemongrass leaf tea is a water extract with little oil, and the kidney and other findings from tea studies do not describe the oil. The herb and tea have their own pages. Do not use tea results to judge the oil, or the other way round.

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What regulators say

We found no EMA monograph, no NCCIH lemongrass entry and no FDA approval of the oil as a medicine. EFSA treats the oil as a skin and respiratory sensitiser. LactMed says no valid trials support lemongrass for milk supply, and relays that the FDA treats the oil as GRAS in foods. An industry panel (FEMA) affirmed it as GRAS for flavour use only.

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At a glance

Traditional uses history, not proof

  • Scent in aromatherapy, perfumes and cosmetics.
  • Flavouring in food (an industry panel affirmed it as GRAS for flavour use; FDA status relayed by LactMed).
  • Plant-based insect repellent, often alongside citronella oil.

Studied for research

  • Anxiety around dental work, scent, very low
  • Dandruff, hair tonic with the oil, low
  • Pityriasis versicolor (yeast skin infection), oil shampoo and cream, low
  • Mosquito repellency, in products, low
  • Bad breath and gum inflammation, mouth rinses, very low
  • Menopausal symptoms, scent sessions, insufficient
  • Nicotine dependence, inhaler, insufficient

Main compounds

  • Citral (geranial and neral), the main compounds and the main allergen
  • Geraniol
  • Myrcene and limonene, named by LactMed

Common forms

  • Essential oil (distilled from the leaves)
  • Scent: diffuser or inhaler blends
  • Made products: hair tonic, shampoo and cream, mouth rinse, repellents
  • Lemongrass herb and tea (different products)

Research links: EFSA: Lemongrass oil opinion (abstract) · Poison Control: Essential oils · Pet Poison Helpline: Essential oils · ASPCA: Lemon grass (plant) · NCCIH: Aromatherapy · Skin allergy to essential oils, IVDK data (abstract) · Research Library · Genes & Biomarkers Library

What it is and its history

Accepted scientific name
Cymbopogon citratus (DC.) Stapf; the oil also comes from Cymbopogon flexuosus (Nees ex Steud.) W.Watson
Naming authority
(DC.) Stapf, Bulletin of Miscellaneous Information, Kew 1906: 322 (GBIF)
Synonyms
Andropogon citratus DC.; Andropogon citratus DC. ex Nees; Andropogon citriodorus Desf.; Andropogon cerifer Hack.; Andropogon roxburghii Nees ex Steud.
Common names
Lemongrass oil (English); Lemongrass essential oil (English); West Indian lemongrass (C. citratus) (English); East Indian lemongrass (C. flexuosus) (English)
Family or group
Poaceae (grass family). Cymbopogon is the lemongrass and citronella genus.
Classification
Plantae > Tracheophyta > Liliopsida > Poales > Poaceae > Cymbopogon > Cymbopogon citratus
Native range
NOT verified from a primary source. Commonly described as a tropical grass of Asia grown widely in the tropics (general knowledge).
Habitat
NOT verified.
What it looks like
Part used: The oil comes from the leaves or aerial parts. Blanco 2009 distilled fresh C. citratus leaves; EFSA describes oil from the aerial parts of C. flexuosus. Steam distillation is the usual method (graph summary; not re-checked here).
Look-alikes and adulterants
Name: Cymbopogon flexuosus (Nees ex Steud.) W.Watson (East Indian lemongrass); Note: A separate accepted species in GBIF (key 8571291). The dandruff trial and the diabetic-rat study used this species' oil, whose main compounds in one analysis were alpha-citral 53.21% and neral 19.42%. Do not assume results carry over to C. citratus.; Name: Cymbopogon nardus (L.) Rendle and Cymbopogon winterianus Jowitt ex Bor (citronella grasses); Note: Separate accepted species in GBIF (keys 2705267 and 2705273). Their oil is rich in citronellal and is used in insect repellents; a mouse study compared C. winterianus and C. citratus oils and found the lemongrass oil stronger on seizures.
Sustainability and conservation
Not verified. Lemongrass is a widely grown crop.

Traditional use and history history, not clinical proof

Tradition or eraDocumented useSource
Aromatherapy and perfumeryLemongrass oil is a common aromatherapy and cosmetic scent. NCCIH describes aromatherapy as the use of essential oils, most often inhaled or applied diluted to the skin, but its page does not name lemongrass.NCCIH
Food flavouringLemongrass oil is used as a food flavouring; an industry panel affirmed it as GRAS for flavour use, and LactMed relays that the FDA treats it as GRAS in foods.FEMA expert panel; LactMed
Repellent useLemongrass and citronella grasses are used in natural insect repellents; human tests show short protection compared with DEET.Faridah 2026
Origin and spread of the plant; EU and other herbal historiesNOT verified. No EMA/HMPC monograph was found and no primary historical source was read.s-ema-hmpc-lemongrass-not-found

Traditional use shows how it was used. It does not show that it works or is safe today.

What is inside, and how it may work

What it contains and how those compounds act in cells and animals. Laboratory and animal mechanisms are not proven effects in people.

Main compounds

CompoundFamilyWhere it is concentratedActivity studiedLevel of evidence
Citral (geranial, trans form)
PubChem 638011
acyclic monoterpene aldehydeLeaf (essential oil)
About 65-85% of the oil (a review); one C. flexuosus oil analysis found alpha-citral 53.21% plus neral 19.42% (72.63% total citral)
In cells, citral activated PPAR alpha and gamma and lowered COX-2 (inflammation enzyme). A skin sensitiser: a human no-effect level for inducing allergy was estimated at 1400 micrograms/cm2 (fragrance-industry authors). Unstable in air. 34 17 18 21Laboratory research
Neral (cis citral)
PubChem 643779
acyclic monoterpene aldehydeLeaf (essential oil)
19.42% of a C. flexuosus oil sample
Part of citral; separate effects not tested in the abstracts read. 17Unknown
Geraniol
PubChem 637566
acyclic monoterpene alcoholLeaf (essential oil)
Named as an oil component by LactMed and in a review of the oil
Named as an oil component. Its separate effects were not tested in the oil studies read here. 28Unknown
Beta-myrcene
PubChem 31253
monoterpene hydrocarbonLeaf (essential oil)
Named as an oil component by LactMed
Not tested in the abstracts read. 28Unknown
Limonene
PubChem 22311
monoterpene hydrocarbonLeaf (essential oil)
Named as an oil component by LactMed
Not tested in the abstracts read. 28Unknown
Citronellal
PubChem 7794
monoterpene aldehydeLeaf (essential oil)
Reported in lemongrass in the title of a pain study; the abstract was not read
Title of a 2011 J Med Food paper (PMID 21480794): 'Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass'. NOT verified beyond the title. 24Unknown

Mechanisms, receptors and pathways

Target or pathwayGene or receptorWhat was foundLevel
PPAR alpha and gamma activation; COX-2 suppressionPPARA, PPARG, PTGS2 (COX-2)Citral activated PPAR alpha and gamma and lowered COX-2 in human macrophage-like cells, which may explain anti-inflammatory effects. 18Laboratory research
GABA-A (benzodiazepine) site involvement in anti-seizure and sedative effectsGABA-A receptorIn mice, injected lemongrass oil delayed seizures; flumazenil blocked the effect and adding oil to a low diazepam dose strengthened it. 35Animal research
Sedative, anti-anxiety and anti-seizure effects in mice by mouthunspecifiedOral oil at 0.5 or 1.0 g/kg lengthened barbiturate sleep and delayed seizures in mice. 2Animal research
Killing of mouth bacteriabacterial cell effectsThe oil was active against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis and less active against Streptococcus mutans in dish tests. 33Laboratory research
Inflammation marker release (MPO) from white cellsmyeloperoxidaseBoth Cymbopogon oils blocked MPO release from human neutrophils in the dish without cell damage (LDH). 35Laboratory research
Antifungal activityfungal cell effectsThe pityriasis versicolor trial was designed around the oil's antifungal action; the human result was partial (about 60% cure, below the standard drug). 4Human (partial)

Absorption, metabolism and elimination

Absorption
A review says oil compounds are quickly absorbed after oral, lung and skin exposure; reliable human data are lacking.
Distribution
Not established in people.
Metabolism
Swallowed citral is reportedly metabolised to acids and a biliary glucuronide (review). No data on the oil on skin or inhaled.
Elimination
Via urine, faeces and exhaled volatiles (review statement). No human numbers.
Bioavailability
Unknown in people. A review says there is no scientific evidence on long-term bioavailability of citral.

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Isolated compounds versus whole extracts

The essential oil is mostly citral with geraniol, myrcene and other terpenes. It is not the same as lemongrass leaf tea (a water extract with little oil) or the whole herb, and results do not carry across. Citral, the main compound, is itself the skin sensitiser; whole oil and isolated citral behaved differently in some tests. The two species, C. citratus and C. flexuosus, also differ, and trials used both.

Nutritional composition

Lemongrass oil is not a nutrient. It is a concentrated flavour and fragrance product.

14benefits and uses looked at
40studies and sources checked
Low certaintybest evidence rating found
8lab markers tracked in trials

3 low certainty6 very low certainty5 not enough evidence

What was looked at

The 14 benefits and uses checked for Lemongrass Oil, each with how strong the evidence is. Tap one to open it.

Lab markers tracked in the studies

State anxiety and tension (self-rated)Heart rateDandruff score (D-Squame scale)Mycological cure (yeast cleared on lab culture)Volatile sulphur compounds (bad-breath gases)Plaque index and gingival (gum) indexTotal cholesterolComplete protection time (time before the first mosquito bite)

What is Lemongrass Oil good for?

The uses people ask about and how strong the evidence is for each. Read the certainty label first: none of these is better than low, and several come from a single small trial or from animals.

Dandruff (scalp tonic with lemongrass oil)Low certaintyIn a small Thai trial, a hair tonic with 5% to 15% East Indian lemongrass oil cut dandruff scores by about half or more in 2 weeks, with the 10% tonic doing best. It used a different species and has not been repeated. Pityriasis versicolor (yeast skin infection, topical oil)Low certaintyIn a Brazilian pilot study, a shampoo and cream with lemongrass oil cleared the yeast in about 60% of people who finished, compared with over 80% for a ketoconazole version. The standard drug did better. Mosquito repellency (oil in repellent products)Low certaintyPlant oils including lemongrass may keep mosquitoes off for a short time. A 2026 review of human studies said oil-based repellents (citronella, lemon eucalyptus, neem, lemongrass) usually protect two to four hours, less than DEET. A 2002 volunteer test found most botanical repellents protected for under 20 minutes. Results disagree and are for products, not plain oil. Calmer feelings after smelling lemongrass oil (lab stress test)Very low certaintyIn one small trial, healthy young men who breathed lemongrass oil for a short time felt less anxious and tense, and bounced back faster from a stressful task. It is one small study of a smell, not a treatment for anxiety. Anxiety and heart rate during gum treatment (aroma in the dental chair)Very low certaintyIn a small Iranian trial, adults who breathed lemongrass oil during a deep gum clean had lower anxiety, blood pressure and heart rate than adults who had no aroma. People knew which group they were in. Calming and anti-seizure effects (mice, large doses of oil)Very low certaintyIn mice, lemongrass oil made sedatives work longer, lowered signs of anxiety and made seizures harder to trigger. These were large doses, by mouth or injected, and they have not been tested in people. Bad breath (lemongrass oil mouth rinse)Very low certaintyA tiny Thai trial found a lemongrass oil mouth rinse lowered bad-breath gases after 8 days. Volunteers did not like the spicy taste. Gum inflammation and plaque (0.25% lemongrass oil mouthwash)Very low certaintyIn a small Indian trial of braces patients, a 0.25% lemongrass mouthwash gave lower plaque and gum scores than a chlorhexidine mouthwash after 2 to 3 weeks. That is an unusual result and needs repeating. Cholesterol and blood fats (swallowed oil capsules, 1989)Very low certaintyA 1989 study of 22 people with very high cholesterol gave lemongrass oil capsules for 90 days. On average the drop just missed statistical significance; 8 people dropped a lot and 14 did not respond. There was no placebo group. This does not make swallowing the oil advisable. Anxiety in children having dental treatment (lemongrass aroma as a distraction)Not enough evidenceIn a large Indian trial of 5 ways to distract anxious children, all five (including lemongrass aroma) were linked to lower anxiety scores, but music and visual distraction did better than smell or taste. Nicotine dependence (3% lemongrass inhaler, one trial)Not enough evidenceOne 2026 trial of 100 young adult smokers reported lower dependence scores with a lemongrass oil inhaler than with a placebo inhaler over eight weeks. It is a single report with surprising results and no repeat, so it is not evidence that the oil helps people quit. Blood sugar and diabetes (rat studies only)Not enough evidenceNo human trial tests lemongrass oil for diabetes. In rats with induced diabetes, lemongrass oil (Cymbopogon flexuosus) lowered blood sugar. That is animal work only. Menopausal symptoms (aromatherapy)Not enough evidenceA 2025 Indonesian trial found fewer menopausal symptoms after four weeks of daily aroma sessions with ginger oil, lemongrass oil or both. The abstract's numbers do not add up and there is no no-aroma group described. Inflammation (lab findings only)Not enough evidenceIn cells, lemongrass oil and its main compound citral lowered an inflammation enzyme. No trial tests this in people.

Benefits, one by one

Each card is a research question, not a promise. Tap a goal to filter. Open a card to see the studies, doses and limits.

Calmer feelings after smelling lemongrass oil (lab stress test)

Very low certainty

In one small trial, healthy young men who breathed lemongrass oil for a short time felt less anxious and tense, and bounced back faster from a stressful task. It is one small study of a smell, not a treatment for anxiety.

1 studiesLemongrass (Cymbopogon citratus) essential oil, 3 or 6 drops inhaled …

Studies, doses and limits

What the trials found

Goes 2015: 40 healthy men, randomly placed in four groups. They breathed lemongrass oil (3 or 6 drops), tea tree oil (control smell) or water, then did a stressful colour-word test on video. State anxiety and tension were lower right after the lemongrass aroma, and the lemongrass groups recovered from the test in 5 minutes, unlike controls. Heart rate and muscle tension changes during the test were not prevented, the same as seen with diazepam in earlier work.

Results

Positive on self-rated anxiety and tension; no protection of body measures (heart rate, muscle activity).

Effect sizes as reported

Statistically significant versus tea tree and water on state anxiety and subjective tension; numbers not given in the abstract.

Why this rating

One trial of 40 young men, single short exposure, anxiety induced in the lab, no replication found. Self-rated scores are easily affected by smell and expectation.

Form and dose studied

Lemongrass (Cymbopogon citratus) essential oil, 3 or 6 drops inhaled once.

Who was studied

Healthy adult men (about 10 per group).

Limits

Healthy volunteers, not people with an anxiety disorder; single exposure; the abstract gives no numbers; no long-term data.

Why researchers looked

Lemongrass is a popular aromatherapy scent and is said to be calming, so researchers tested the aroma directly.

Traditional use

Lemongrass scent is used in aromatherapy for calm. No regulator we found accepts it for anxiety.

Proposed mechanism Animal research

Not worked out in people. In mice, lemongrass oil effects were blocked by flumazenil, which points to the brain's GABA calming system, but that was with injected oil.

A proposed mechanism does not show that the effect happens in people.

Safety is covered in the safety section. Lemongrass essential oil is a strong oil: it can cause skin allergy, and it should not be swallowed on the strength of these results.

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Anxiety and heart rate during gum treatment (aroma in the dental chair)

Very low certainty

In a small Iranian trial, adults who breathed lemongrass oil during a deep gum clean had lower anxiety, blood pressure and heart rate than adults who had no aroma. People knew which group they were in.

1 studiesLemongrass essential oil aroma during one treatment session; the oil …

Studies, doses and limits

What the trials found

Maybodi 2025: 38 patients having scaling and root planing (a deep gum clean). One group inhaled lemongrass oil during the work; the control group had the work with no aroma. The lemongrass group had lower systolic and diastolic blood pressure, heart rate and anxiety scores. Oxygen saturation, pain and satisfaction did not differ. Registered as IRCT20230615058492N2.

Results

Better on anxiety, blood pressure and heart rate after one session; no difference in pain or satisfaction.

Effect sizes as reported

Significant reductions reported for anxiety, systolic and diastolic blood pressure and heart rate; numbers not given in the abstract.

Why this rating

Very small (38), one session, no placebo aroma so people could tell their group, and anxiety is self-rated. Authors say lemongrass 'appears beneficial'.

Form and dose studied

Lemongrass essential oil aroma during one treatment session; the oil and amount are not given in the abstract.

Who was studied

Adults with gum disease treated at a university dental clinic in Yazd, Iran.

Limits

No blinding to aroma, single centre, short effect; the blood pressure change is a response to a nervous situation, not treatment of high blood pressure.

Why researchers looked

Dental visits cause worry that raises blood pressure and heart rate. Aromatherapy is a low-cost add-on researchers have tried.

Traditional use

No traditional use of lemongrass in the dental chair; aromatherapy use is modern.

Proposed mechanism Pharmacological theory

Not known. Possible effects of the smell on the brain's stress response are theory only.

A proposed mechanism does not show that the effect happens in people.

Safety is covered in the safety section. Lemongrass essential oil is a strong oil: it can cause skin allergy, and it should not be swallowed on the strength of these results.

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Anxiety in children having dental treatment (lemongrass aroma as a distraction)

Not enough evidence

In a large Indian trial of 5 ways to distract anxious children, all five (including lemongrass aroma) were linked to lower anxiety scores, but music and visual distraction did better than smell or taste.

1 studiesLemongrass oil aromatherapy during one dental visit; amount not in th…

Studies, doses and limits

What the trials found

Chawla 2025: 350 children aged 6 to 9, 70 in each of five groups: cards, lemongrass aroma, music, acupressure, honey taste. Every group had lower anxiety after treatment (P < 0.001). The abstract says music was best (mean change 1.10), visual next (1.04), and that smell and taste were less effective than those two. No lemongrass-specific number is given.

Results

Anxiety lower in the lemongrass aroma group, but less than with music or visual distraction; no figure in the abstract.

Effect sizes as reported

All groups P < 0.001 before versus after; lemongrass group number not in the abstract.

Why this rating

The abstract does not show a no-treatment group or a lemongrass figure, so it cannot show that the lemongrass smell, rather than the dental setting or the passing of time, lowered anxiety.

Form and dose studied

Lemongrass oil aromatherapy during one dental visit; amount not in the abstract.

Who was studied

Children aged 6 to 9 in India.

Limits

No lemongrass result in the abstract, no untreated comparison described, children's anxiety scale.

Why researchers looked

Fear of the dentist is common in children, and non-drug distraction methods are tried first.

Proposed mechanism Pharmacological theory

Not known; distraction and smell effects are theory.

A proposed mechanism does not show that the effect happens in people.

Essential oils should not be swallowed by children. This trial used the aroma only. Poison-centre guidance on children was not read here.

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Calming and anti-seizure effects (mice, large doses of oil)

Very low certainty

In mice, lemongrass oil made sedatives work longer, lowered signs of anxiety and made seizures harder to trigger. These were large doses, by mouth or injected, and they have not been tested in people.

2 studiesEssential oil, 0.5 to 1.0 g/kg by mouth (Blanco) or 50 to 200 mg/kg b…

Studies, doses and limits

Results

Positive in two mouse studies with the oil (given by mouth or injected); not tested in people.

Effect sizes as reported

Significant effects in mice; numbers not in the abstracts.

Why this rating

Animal data only; no human study of these effects.

Form and dose studied

Essential oil, 0.5 to 1.0 g/kg by mouth (Blanco) or 50 to 200 mg/kg by injection (Silva) in mice.

Who was studied

Mice; not applicable to people.

Limits

Large doses of oil by mouth or injection in mice. This says nothing about breathing a small amount of scent, and swallowing the oil is not advised.

Why researchers looked

To see whether the oil acts on the brain in animals, which might explain the calming reputation of the scent.

Proposed mechanism Animal research

Mouse work links the oil effect to the GABA system (the brain's main calming system), because flumazenil, a drug that blocks it, blocked the effect (Silva 2010, injected oil). Low doses of oil added to low doses of diazepam made the effect stronger.

A proposed mechanism does not show that the effect happens in people.

The animal results suggest that lemongrass oil could add to sedative medicines (see the interactions in the safety section).

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Nicotine dependence (3% lemongrass inhaler, one trial)

Not enough evidence

One 2026 trial of 100 young adult smokers reported lower dependence scores with a lemongrass oil inhaler than with a placebo inhaler over eight weeks. It is a single report with surprising results and no repeat, so it is not evidence that the oil helps people quit.

1 studiesNot covered. This page gives no amounts and no ways of using the oil.

Studies, doses and limits

What the trials found

Kumboyono 2026: 100 smokers aged 18 to 30, 3% lemongrass inhaler or placebo four times daily for eight weeks. The abstract reports a larger fall in the Fagerstrom dependence score (mean difference 2.3, p<0.001) and in a serum receptor marker (0.6 ng/mL, p=0.003).

Results

Lower self-rated dependence score than placebo. No quitting rate is described in the abstract.

Effect sizes as reported

FTND mean difference 2.3 (p<0.001); partial eta squared 0.390 (authors call it a large effect).

Why this rating

One report from one group, read as an abstract, with an unusually large effect for a scent, an unusual blood marker, and no replication.

Form and dose studied

Not covered. This page gives no amounts and no ways of using the oil.

Who was studied

Adult smokers aged 18 to 30 with moderate-to-high dependence.

Limits

Single trial, short follow-up, no abstinence outcome in the abstract, funding not stated, not repeated.

Why researchers looked

Citral, the main scent compound, was proposed to act on nicotine receptors in the brain.

Proposed mechanism Hypothesis

The authors propose that citral changes nicotinic receptor activity. This was not shown in the abstract beyond a blood marker.

A proposed mechanism does not show that the effect happens in people.

Do not treat this as a way to stop smoking. Ask a doctor or pharmacist about proven help.

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Dandruff (scalp tonic with lemongrass oil)

Low certainty

In a small Thai trial, a hair tonic with 5% to 15% East Indian lemongrass oil cut dandruff scores by about half or more in 2 weeks, with the 10% tonic doing best. It used a different species and has not been repeated.

2 studiesHair tonic with 5%, 10% or 15% lemongrass (C. flexuosus) essential oi…

Studies, doses and limits

What the trials found

Chaisripipat 2015: 30 volunteers with moderate dandruff in a double-blind, placebo-controlled split-head test applied tonics twice a day. Dandruff scores fell 33%, 75% and 51% at day 7 and 52%, 81% and 74% at day 14 with 5%, 10% and 15% oil. No details on side effects are in the abstract.

Results

Large, rapid reductions in dandruff score in a small trial.

Effect sizes as reported

Reductions of 52%, 81% and 74% at day 14 (5%, 10%, 15% oil), P < 0.005; the placebo result is not given in the abstract.

Why this rating

A double-blind placebo-controlled design is a strength, but there are only 30 people, 2 weeks, no repeat, and the oil was from Cymbopogon flexuosus, not C. citratus.

Form and dose studied

Hair tonic with 5%, 10% or 15% lemongrass (C. flexuosus) essential oil, twice a day for 14 days.

Who was studied

Thai adults aged 20 to 60 with dandruff.

Limits

Different species, tiny trial, short, no follow-up, cosmetic-science team. The abstract does not report skin irritation.

Why researchers looked

Dandruff is linked to Malassezia yeasts, and lemongrass oil kills yeasts in the dish.

Traditional use

Not a documented traditional use in the sources read.

Proposed mechanism Laboratory research

Citral and other oil compounds kill or slow yeasts in laboratory tests; Malassezia was targeted in the trial's design.

A proposed mechanism does not show that the effect happens in people.

Lemongrass oil is a known skin allergen (see the safety section); do not put undiluted oil on skin.

5 20

Pityriasis versicolor (yeast skin infection, topical oil)

Low certainty

In a Brazilian pilot study, a shampoo and cream with lemongrass oil cleared the yeast in about 60% of people who finished, compared with over 80% for a ketoconazole version. The standard drug did better.

2 studiesLemongrass (C. citratus) essential oil at 1.25 microlitres/mL in sham…

Studies, doses and limits

What the trials found

Carmo 2013: Phase I in 20 healthy volunteers found no significant adverse events. In phase II, 47 people received the oil shampoo and cream and 29 received ketoconazole versions for 40 days. 30 (63.83%) on oil and 18 (62.07%) on ketoconazole finished. Mycological cure was 60% with the oil and over 80% with ketoconazole.

Results

Some antifungal effect, less than the standard drug; many dropped out.

Effect sizes as reported

60% cure (oil) versus over 80% (ketoconazole) at 40 days, both P < 0.05.

Why this rating

A randomised pilot against a standard drug with a measured cure rate, but small, about a third dropped out, no placebo, and the drug was better.

Form and dose studied

Lemongrass (C. citratus) essential oil at 1.25 microlitres/mL in shampoo (3 times a week) and cream (twice a day) for 40 days.

Who was studied

76 people with pityriasis versicolor, Brazil (plus 20 healthy volunteers for safety).

Limits

Pilot, high dropout, no placebo arm, culture-based cure.

Why researchers looked

Lemongrass oil is active against Malassezia yeasts in the dish.

Traditional use

Not a documented traditional use in the sources read.

Proposed mechanism Laboratory research

Oil compounds damage yeast cells in laboratory tests.

A proposed mechanism does not show that the effect happens in people.

Skin allergy to lemongrass oil is possible; see the safety section.

4 20

Bad breath (lemongrass oil mouth rinse)

Very low certainty

A tiny Thai trial found a lemongrass oil mouth rinse lowered bad-breath gases after 8 days. Volunteers did not like the spicy taste.

1 studiesLemongrass oil mouth rinse; concentration not in the abstract.

Studies, doses and limits

What the trials found

Satthanakul 2015: 20 healthy volunteers in a double-blind trial measured bad-breath gases with a Halimeter on day 0 and day 8. The rinse significantly reduced them on day 8 and appeared safe. Spiciness and taste were drawbacks.

Results

Positive, small, short.

Effect sizes as reported

Significant fall in volatile sulphur compounds on day 8; numbers not in the abstract.

Why this rating

Twenty healthy people, a pilot, 8 days, no numbers in the abstract.

Form and dose studied

Lemongrass oil mouth rinse; concentration not in the abstract.

Who was studied

Healthy adult volunteers, Thailand.

Limits

Pilot; healthy people; no long-term data.

Why researchers looked

Bad breath comes from mouth bacteria making sulphur gases, and lemongrass oil kills several of them in the dish.

Proposed mechanism Laboratory research

In the dish the oil was active against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis and less so against Streptococcus mutans.

A proposed mechanism does not show that the effect happens in people.

Rinses should not be swallowed. Mouth and gum irritation was not reported in the abstract.

33

Gum inflammation and plaque (0.25% lemongrass oil mouthwash)

Very low certainty

In a small Indian trial of braces patients, a 0.25% lemongrass mouthwash gave lower plaque and gum scores than a chlorhexidine mouthwash after 2 to 3 weeks. That is an unusual result and needs repeating.

3 studiesLemongrass oil 0.25% mouthwash, twice a day (21 days; Wasey) or 3 mon…

Studies, doses and limits

What the trials found

Wasey 2023: 60 orthodontic patients with mild-to-moderate gingivitis, 20 per group: 0.25% lemongrass oil mouthwash, 0.2% chlorhexidine, or oral cleaning only, for 21 days. Plaque and gum scores were lower with lemongrass than chlorhexidine by day 14 and day 21 (P < 0.001). In another small trial of severe gum disease (Subha 2017, 15 per group, 3 months), pocket depth and attachment loss improved in the lemongrass group and in the chlorhexidine group compared with cleaning alone.

Results

Positive in two small trials from India; one reports lemongrass better than chlorhexidine.

Effect sizes as reported

P < 0.001 versus chlorhexidine for plaque and gum index (scores not in the abstract).

Why this rating

Groups of 15 to 20, short, one setting each, comparisons with a gold-standard rinse that came out unusually in favour of the herbal one, no independent repeats found.

Form and dose studied

Lemongrass oil 0.25% mouthwash, twice a day (21 days; Wasey) or 3 months (Subha).

Who was studied

Adults with gum inflammation or periodontitis, India.

Limits

Small, no numbers in the abstracts, authors' links to products not stated.

Why researchers looked

Chlorhexidine mouthwash stains teeth and tastes unpleasant, so a herbal alternative is of interest.

Proposed mechanism Laboratory research

Oil compounds kill plaque bacteria in the dish.

A proposed mechanism does not show that the effect happens in people.

Do not swallow mouthwash. Contact allergy to lemongrass oil can affect the mouth and lips, though not reported in these trials' abstracts.

39 36 20

Cholesterol and blood fats (swallowed oil capsules, 1989)

Very low certainty

A 1989 study of 22 people with very high cholesterol gave lemongrass oil capsules for 90 days. On average the drop just missed statistical significance; 8 people dropped a lot and 14 did not respond. There was no placebo group. This does not make swallowing the oil advisable.

2 studiesNot covered. This page gives no amounts and no ways of using the oil.

Studies, doses and limits

What the trials found

Elson 1989: 22 people with raised cholesterol, lemongrass oil capsules for 90 days, no placebo group. A mouthwash trial in braces patients also measured blood fats and CRP (Subha 2017).

Results

The average fall in cholesterol just missed statistical significance in the capsule study; 8 people had a large fall and 14 did not respond.

Effect sizes as reported

Responders -38 +/- 10 mg/dl at 90 days (P < 0.025); non-responders -1 +/- 6; whole group P < 0.06.

Why this rating

One small uncontrolled study from 1989; no repeat.

Form and dose studied

Not covered. This page gives no amounts and no ways of using the oil.

Who was studied

People with high cholesterol.

Limits

No placebo group, small, old, and it used swallowed oil capsules, which this page does not advise.

Why researchers looked

A theory that compounds in lemongrass oil (geraniol and citral) could lower cholesterol by slowing its production.

Traditional use

Not a documented traditional use in the sources read.

Proposed mechanism Laboratory research

Oil compounds that touch the cholesterol-building pathway (mevalonate) were thought to lower cholesterol; citral also switches on PPAR-alpha and gamma in cells, which handle fats.

A proposed mechanism does not show that the effect happens in people.

Swallowed lemongrass oil capsules are not an approved use; the study did not report side effects in its abstract.

9 36

Blood sugar and diabetes (rat studies only)

Not enough evidence

No human trial tests lemongrass oil for diabetes. In rats with induced diabetes, lemongrass oil (Cymbopogon flexuosus) lowered blood sugar. That is animal work only.

2 studiesNot covered. This page gives no amounts and no ways of using the oil.

Studies, doses and limits

Results

Lower blood glucose in diabetic rats given oil by mouth (Junior 2024). No human result.

Effect sizes as reported

Numbers not given in the abstracts.

Why this rating

Only rat data; no human trial.

Form and dose studied

Not covered. This page gives no amounts and no ways of using the oil.

Who was studied

Rats.

Limits

Rats only, doses far above scent exposure.

Why researchers looked

Folk and lab interest in lemongrass for diabetes; citral activates PPAR switches that affect sugar and fat handling in cells.

Traditional use

Not a documented traditional use in the sources read.

Proposed mechanism Laboratory research

Citral activated PPAR alpha and gamma in cell work (Katsukawa 2010).

A proposed mechanism does not show that the effect happens in people.

People using diabetes medicines should tell their doctor before using any lemongrass product in larger amounts (theory only).

17 18

Menopausal symptoms (aromatherapy)

Not enough evidence

A 2025 Indonesian trial found fewer menopausal symptoms after four weeks of daily aroma sessions with ginger oil, lemongrass oil or both. The abstract's numbers do not add up and there is no no-aroma group described.

1 studiesLemongrass oil aroma, 20 minutes a day for 4 weeks (alone, or combine…

Studies, doses and limits

What the trials found

Sari 2025: women at a public health centre received a 20-minute aroma session daily for 4 weeks with ginger oil, lemongrass oil, or both. All three arms had significantly lower Menopause Assessment Scale scores. The abstract says 355 women but 89 per arm (3 x 89 = 267), so the real size is unclear.

Results

Symptom scores fell in all arms, including lemongrass alone.

Effect sizes as reported

Statistically significant reductions in all three groups; numbers not given.

Why this rating

No comparison with no aroma is described, the numbers are inconsistent, and a combination arm is mixed with ginger.

Form and dose studied

Lemongrass oil aroma, 20 minutes a day for 4 weeks (alone, or combined with ginger oil).

Who was studied

Menopausal women, Indonesia.

Limits

No clear control; participant numbers inconsistent.

Why researchers looked

Aromatherapy is used for menopausal discomfort.

Proposed mechanism Pharmacological theory

Not known.

A proposed mechanism does not show that the effect happens in people.

Safety is covered in the safety section. Lemongrass essential oil is a strong oil: it can cause skin allergy, and it should not be swallowed on the strength of these results.

32

Inflammation (lab findings only)

Not enough evidence

In cells, lemongrass oil and its main compound citral lowered an inflammation enzyme. No trial tests this in people.

2 studiesNot covered. This page gives no amounts and no ways of using the oil.

Studies, doses and limits

Results

Lab and animal only.

Effect sizes as reported

Dose-dependent COX-2 suppression in cells.

Why this rating

Cell and rat work; not a human result.

Form and dose studied

Not covered. This page gives no amounts and no ways of using the oil.

Who was studied

Cells; rats.

Limits

No human trial.

Why researchers looked

To explain folk use for pain and swelling.

Traditional use

Cuban folk use as an anti-inflammatory (Carbajal 1989).

Proposed mechanism Laboratory research

Citral activated PPAR alpha and gamma and lowered COX-2 expression in human macrophage-like cells (Katsukawa 2010). Both Cymbopogon oils blocked release of the inflammation marker MPO from human white cells in the dish (Silva 2010).

A proposed mechanism does not show that the effect happens in people.

None specific.

18 35

Mosquito repellency (oil in repellent products)

Low certainty

Plant oils including lemongrass may keep mosquitoes off for a short time. A 2026 review of human studies said oil-based repellents (citronella, lemon eucalyptus, neem, lemongrass) usually protect two to four hours, less than DEET. A 2002 volunteer test found most botanical repellents protected for under 20 minutes. Results disagree and are for products, not plain oil.

2 studiesNot covered. This page gives no amounts and no ways of using the oil.

Studies, doses and limits

What the trials found

Faridah 2026: systematic review of 19 human studies of repellents. Fradin 2002: 15 volunteers tested seven botanical repellents (oils not named in the abstract), DEET products and others in a mosquito room.

Results

Short protection compared with DEET in both; the 2002 test found botanical repellents mostly under 20 minutes, the 2026 review commonly two to four hours.

Effect sizes as reported

Review: natural repellents commonly 2 to 4 hours; DEET often 5 to 9 hours. 2002 test: most botanicals under 20 minutes; 23.8% DEET mean 301.5 minutes.

Why this rating

Human data exist but lemongrass is pooled with other oils, products and methods differ widely, and the two sources disagree on how long botanical products work.

Form and dose studied

Not covered. This page gives no amounts and no ways of using the oil.

Who was studied

Adult volunteers in repellent tests.

Limits

Lemongrass is not tested alone in the abstracts read, and the results depend on the product. Not tied to any disease prevention outcome.

Why researchers looked

Citronella-type grasses are used in repellents, and lemongrass oil is a close relative.

Traditional use

Lemongrass and citronella grasses are used as natural repellents in many places (general use; not from a regulator we read).

Proposed mechanism Hypothesis

Not established in the abstracts read. The scent masks or repels mosquitoes.

A proposed mechanism does not show that the effect happens in people.

The CDC recommends EPA-registered repellents where mosquito-borne illness is a risk; the lab and review results here do not make lemongrass oil a replacement.

11 12

Connections to the rest of health

How Lemongrass Oil connects to the rest of our health knowledge graph. Every link says what kind of connection it is. A safety link (for example to the liver) is a warning, not a benefit. A study that merely mentions a topic never creates a benefit link.

Explore every connection: goals, body systems, organs, symptoms, genes

A. Wellness goals

Connected toKind of connectionEvidence statusContextStudies
Anxiety Support Potential benefit Very low certainty Calmer feelings after smelling lemongrass oil (lab stress test): In one small trial, healthy young men who breathed lemongrass oil for a short time felt less anxious and tense, and bounced back faster from a stressful task. It is one small study of a smell, not a treatment for anxiety. Anxiety and heart rate during gum treatment (aroma in the dental chair): In a small Iranian trial, adults who breathed lemongrass oil during a deep gum clean had lower anxiety, blood pressure and heart rate than adults who had no aroma. People knew which group they were in. 16 22 6
Calm Relaxation Potential benefit Very low certainty Calmer feelings after smelling lemongrass oil (lab stress test): In one small trial, healthy young men who breathed lemongrass oil for a short time felt less anxious and tense, and bounced back faster from a stressful task. It is one small study of a smell, not a treatment for anxiety. Anxiety and heart rate during gum treatment (aroma in the dental chair): In a small Iranian trial, adults who breathed lemongrass oil during a deep gum clean had lower anxiety, blood pressure and heart rate than adults who had no aroma. People knew which group they were in. 16 22 6
Stress Reduction Potential benefit Very low certainty Calmer feelings after smelling lemongrass oil (lab stress test): In one small trial, healthy young men who breathed lemongrass oil for a short time felt less anxious and tense, and bounced back faster from a stressful task. It is one small study of a smell, not a treatment for anxiety. Anxiety and heart rate during gum treatment (aroma in the dental chair): In a small Iranian trial, adults who breathed lemongrass oil during a deep gum clean had lower anxiety, blood pressure and heart rate than adults who had no aroma. People knew which group they were in. 16 22
Blood Pressure Support Potential benefit Very low certainty Anxiety and heart rate during gum treatment (aroma in the dental chair): In a small Iranian trial, adults who breathed lemongrass oil during a deep gum clean had lower anxiety, blood pressure and heart rate than adults who had no aroma. People knew which group they were in. 22
Calm Relaxation Preliminary mechanism Very low certainty Calming and anti-seizure effects (mice, large doses of oil): In mice, lemongrass oil made sedatives work longer, lowered signs of anxiety and made seizures harder to trigger. These were large doses, by mouth or injected, and they have not been tested in people. 2 35
Anxiety Support Preliminary mechanism Very low certainty Calming and anti-seizure effects (mice, large doses of oil): In mice, lemongrass oil made sedatives work longer, lowered signs of anxiety and made seizures harder to trigger. These were large doses, by mouth or injected, and they have not been tested in people. 2 35
Better Sleep Preliminary mechanism Very low certainty Calming and anti-seizure effects (mice, large doses of oil): In mice, lemongrass oil made sedatives work longer, lowered signs of anxiety and made seizures harder to trigger. These were large doses, by mouth or injected, and they have not been tested in people. 2 35
Anxiety Support Not enough evidence Nicotine dependence (3% lemongrass inhaler, one trial): One 2026 trial of 100 young adult smokers reported lower dependence scores with a lemongrass oil inhaler than with a placebo inhaler over eight weeks. It is a single report with surprising results and no repeat, so it is not evidence that the oil helps people quit. 19
Hair Support Potential benefit Low certainty Dandruff (scalp tonic with lemongrass oil): In a small Thai trial, a hair tonic with 5% to 15% East Indian lemongrass oil cut dandruff scores by about half or more in 2 weeks, with the 10% tonic doing best. It used a different species and has not been repeated. 5 20
Healthy Skin Potential benefit Low certainty Dandruff (scalp tonic with lemongrass oil): In a small Thai trial, a hair tonic with 5% to 15% East Indian lemongrass oil cut dandruff scores by about half or more in 2 weeks, with the 10% tonic doing best. It used a different species and has not been repeated. Pityriasis versicolor (yeast skin infection, topical oil): In a Brazilian pilot study, a shampoo and cream with lemongrass oil cleared the yeast in about 60% of people who finished, compared with over 80% for a ketoconazole version. The standard drug did better. 5 20 4 11 12
Digestive Support Potential benefit Very low certainty Bad breath (lemongrass oil mouth rinse): A tiny Thai trial found a lemongrass oil mouth rinse lowered bad-breath gases after 8 days. Volunteers did not like the spicy taste. Gum inflammation and plaque (0.25% lemongrass oil mouthwash): In a small Indian trial of braces patients, a 0.25% lemongrass mouthwash gave lower plaque and gum scores than a chlorhexidine mouthwash after 2 to 3 weeks. That is an unusual result and needs repeating. 33 39 36 20
Gut Health Potential benefit Very low certainty Bad breath (lemongrass oil mouth rinse): A tiny Thai trial found a lemongrass oil mouth rinse lowered bad-breath gases after 8 days. Volunteers did not like the spicy taste. 33
Immune Support Potential benefit Very low certainty Gum inflammation and plaque (0.25% lemongrass oil mouthwash): In a small Indian trial of braces patients, a 0.25% lemongrass mouthwash gave lower plaque and gum scores than a chlorhexidine mouthwash after 2 to 3 weeks. That is an unusual result and needs repeating. 39 36 20
Cholesterol Balance Potential benefit Very low certainty Cholesterol and blood fats (swallowed oil capsules, 1989): A 1989 study of 22 people with very high cholesterol gave lemongrass oil capsules for 90 days. On average the drop just missed statistical significance; 8 people dropped a lot and 14 did not respond. There was no placebo group. This does not make swallowing the oil advisable. 9 36
Heart Health Potential benefit Very low certainty Cholesterol and blood fats (swallowed oil capsules, 1989): A 1989 study of 22 people with very high cholesterol gave lemongrass oil capsules for 90 days. On average the drop just missed statistical significance; 8 people dropped a lot and 14 did not respond. There was no placebo group. This does not make swallowing the oil advisable. 9 36
Blood Sugar Balance Preliminary mechanism Not enough evidence Blood sugar and diabetes (rat studies only): No human trial tests lemongrass oil for diabetes. In rats with induced diabetes, lemongrass oil (Cymbopogon flexuosus) lowered blood sugar. That is animal work only. 17 18
Metabolic Health Preliminary mechanism Not enough evidence Blood sugar and diabetes (rat studies only): No human trial tests lemongrass oil for diabetes. In rats with induced diabetes, lemongrass oil (Cymbopogon flexuosus) lowered blood sugar. That is animal work only. 17 18
Menopause Support Potential benefit Not enough evidence Menopausal symptoms (aromatherapy): A 2025 Indonesian trial found fewer menopausal symptoms after four weeks of daily aroma sessions with ginger oil, lemongrass oil or both. The abstract's numbers do not add up and there is no no-aroma group described. 32
Womens Wellness Potential benefit Not enough evidence Menopausal symptoms (aromatherapy): A 2025 Indonesian trial found fewer menopausal symptoms after four weeks of daily aroma sessions with ginger oil, lemongrass oil or both. The abstract's numbers do not add up and there is no no-aroma group described. 32
Inflammation Balance Preliminary mechanism Not enough evidence Inflammation (lab findings only): In cells, lemongrass oil and its main compound citral lowered an inflammation enzyme. No trial tests this in people. 18 35

B. Body systems

Connected toKind of connectionEvidence statusContextStudies
Nervous System Biological association Very low certainty Studied for: Calmer feelings after smelling lemongrass oil (lab stress test) Studied for: Anxiety and heart rate during gum treatment (aroma in the dental chair) 16 22 6 2 35 19
Stress Mood Biological association Very low certainty Studied for: Calmer feelings after smelling lemongrass oil (lab stress test) Studied for: Anxiety and heart rate during gum treatment (aroma in the dental chair) 16 22 6
Cardiovascular System Biological association Very low certainty Studied for: Anxiety and heart rate during gum treatment (aroma in the dental chair) Studied for: Cholesterol and blood fats (swallowed oil capsules, 1989) 22 9 36
Integumentary System Biological association Low certainty Studied for: Dandruff (scalp tonic with lemongrass oil) Studied for: Pityriasis versicolor (yeast skin infection, topical oil) 5 20 4
Immune System Biological association Low certainty Studied for: Pityriasis versicolor (yeast skin infection, topical oil) Studied for: Gum inflammation and plaque (0.25% lemongrass oil mouthwash) 4 20 39 36 18 35
Digestive System Biological association Very low certainty Studied for: Bad breath (lemongrass oil mouth rinse) Studied for: Gum inflammation and plaque (0.25% lemongrass oil mouthwash) 33 39 36 20
Metabolism Weight Biological association Very low certainty Studied for: Cholesterol and blood fats (swallowed oil capsules, 1989) Studied for: Blood sugar and diabetes (rat studies only) 9 36 17 18
Endocrine System Biological association Not enough evidence Studied for: Blood sugar and diabetes (rat studies only) Studied for: Menopausal symptoms (aromatherapy) 17 18 32
Reproductive System Biological association Not enough evidence Studied for: Menopausal symptoms (aromatherapy) 32
Skin Hair Beauty Biological association Low certainty Studied for: Mosquito repellency (oil in repellent products) 11 12

C. Body parts and organs

Connected toKind of connectionEvidence statusContextStudies
Skin Adverse effect or risk Low certainty Contact allergy in 2.6% of 10,930 and 1.8% of 15,682 dermatitis patients patch tested; four occupational cases.
Preparation or compound: Lemongrass essential oil (citral)
15 38 3
Lungs and airways Adverse effect or risk Documented risk Regulatory classification; no human diffuser study.
Preparation or compound: Lemongrass oil (respiratory sensitiser per EFSA)
7
Brain Preliminary mechanism Very low certainty Calming, sleep-lengthening and anti-seizure effects in mice linked to GABA; no human data.
Preparation or compound: Lemongrass essential oil
35 2

E. Health conditions

Connected toKind of connectionEvidence statusContextStudies
Contact dermatitis Adverse effect or risk Documented risk Patch-test and case data.
Preparation or compound: Lemongrass oil
15 38 3 40

I. Biomarkers

Connected toKind of connectionEvidence statusContextStudies
State anxiety and tension (self-rated) Biological association Very low certainty Measured in trials: lowered. A lab change is not the same as a health benefit. 16 22
Heart rate Biological association Very low certainty Measured in trials: mixed. A lab change is not the same as a health benefit. 22 16
Dandruff score (D-Squame scale) Biological association Low certainty Measured in trials: lowered. A lab change is not the same as a health benefit. 5
Mycological cure (yeast cleared on lab culture) Biological association Low certainty Measured in trials: lowered. A lab change is not the same as a health benefit. 4
Volatile sulphur compounds (bad-breath gases) Biological association Very low certainty Measured in trials: lowered. A lab change is not the same as a health benefit. 33
Plaque index and gingival (gum) index Biological association Very low certainty Measured in trials: lowered. A lab change is not the same as a health benefit. 39
Total cholesterol Biological association Very low certainty Measured in trials: mixed. A lab change is not the same as a health benefit. 9 36
Complete protection time (time before the first mosquito bite) Biological association Low certainty Measured in trials: increase. A lab change is not the same as a health benefit. 11 12

J. Genes, receptors and enzymes

Connected toKind of connectionEvidence statusContextStudies
PPARA / PPARG Preliminary mechanism In vitro Citral activates PPAR alpha and gamma in cells (inflammation and fat handling). 18
PTGS2 (COX-2) Preliminary mechanism In vitro Citral suppressed LPS-induced COX-2 mRNA and protein in U937 cells. 18
GABA-A receptor Preliminary mechanism Animal Anti-seizure effect of the oil in mice was blocked by flumazenil. 35
Myeloperoxidase (MPO) Preliminary mechanism In vitro Oil blocked its release from human neutrophils in the dish. 35

L. Active compounds

Connected toKind of connectionEvidence statusContextStudies
Citral Adverse effect or risk Low certainty Skin sensitiser; human no-effect level for induction 1400 micrograms per cm2 (fragrance-industry authors).
Preparation or compound: Citral (main compound in the oil)
21
Citral (geranial, trans form) Biological association In vitro In cells, citral activated PPAR alpha and gamma and lowered COX-2 (inflammation enzyme). A skin sensitiser: a human no-effect level for inducing allergy was estimated at 1400 micrograms/cm2 (fragrance-industry authors). Unstable in air.
Preparation or compound: Leaf (essential oil)
34 17 18 21
Neral (cis citral) Biological association Unknown Part of citral; separate effects not tested in the abstracts read.
Preparation or compound: Leaf (essential oil)
17
Geraniol Biological association Unknown Named as an oil component. Its separate effects were not tested in the oil studies read here.
Preparation or compound: Leaf (essential oil)
28
Beta-myrcene Biological association Unknown Not tested in the abstracts read.
Preparation or compound: Leaf (essential oil)
28
Limonene Biological association Unknown Not tested in the abstracts read.
Preparation or compound: Leaf (essential oil)
28
Citronellal Biological association Unknown Title of a 2011 J Med Food paper (PMID 21480794): 'Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass'. NOT verified beyond the title.
Preparation or compound: Leaf (essential oil)
24

Each connection is stored with the ingredient, the connected record, the kind of connection, the evidence status, the supporting studies, the preparation or compound involved, and a review date (last reviewed October 25, 2026).

Evidence at a glance: what changed in 7 lab markers

Tap a number to show only those markers. Counts are markers, not people.

The evidence

The research centre for Lemongrass Oil. Every record here was checked against PubMed or the publisher's page; we never list a study we have not verified.

Evidence by outcome

Bars show how many studies we found for each outcome, not how well it works. People are added up across trials only (reviews are not added, to avoid double counting).

How we rate evidence

High certainty

Several well-run trials or reviews agree; further research is unlikely to change the picture much.

Moderate certainty

Good trials point the same way, but some doubt remains.

Low certainty

Small, short or inconsistent trials. The finding could change with better research.

Very low certainty

Very little or very weak human data. Treat as a possibility only.

Mixed findings

Trials or reviews disagree with each other.

Not enough evidence

Not enough human research to say either way.

Evidence against

Good research found no benefit, or found harm.

We take the reviewers' own risk-of-bias and GRADE statements where they exist, and otherwise judge from study size, design, consistency, directness and whether a product matches what is sold. Many publications do not make evidence high. Method note: We read the abstracts of the PubMed papers listed, plus the Poison Control, Pet Poison Helpline, ASPCA, Tisserand Institute and NCCIH pages, checked plant names in GBIF and NCBI and compounds in PubChem. We could not read LiverTox or an EMA document.

Study library: every study we checked 40
StudyDesignPeopleProduct, dose, lengthResult
ASPCA Animal Poison Control 2026
Toxic and Non-toxic Plants: Lemon Grass
aspca.org, read 2026-10-25 · Source
Authoritative guidance
n/a
Dogs, cats, horses Lemon grass plant (Cymbopogon citratus)
The ASPCA lists lemon grass as toxic to dogs, cats and horses. Signs listed: stomach upset in dogs and cats; difficulty breathing, weakness and (rarely) death in horses.
Methods, limits and funding

Outcomes: Plant toxicity listing

Limitations: This is the plant, not the concentrated oil. It says nothing about diffusers or skin use of the oil.

Read: full-text

Blanco 2009
Neurobehavioral effect of essential oil of Cymbopogon citratus in mice
Phytomedicine · PMID 17561386 · DOI
Animal research
animal
Male Swiss mice Lemongrass essential oil from fresh leaves, by mouth
leaf (oil) 0.5 or 1.0 g/kg Single dose 30 minutes before tests · vs Vehicle
The oil lengthened sleeping time, increased time in open or light areas (an anxiety-lowering sign in mice) and raised the threshold for induced seizures, without impairing movement.
Effects reported as significant at both doses; numbers not in the abstract.
Methods, limits and funding

Outcomes: Pentobarbital sleeping time, elevated plus maze, light/dark box, seizure tests

Limitations: Mouse study at very large doses of oil; says nothing about breathing a small amount of scent.

Funding and conflicts: Not stated in the abstract

Read: abstract

Bleasel 2002
Allergic contact dermatitis following exposure to essential oils
Australas J Dermatol · PMID 12121401 · DOI
Case series
4
Three aromatherapists and one chemist, Australia/New Zealand
Multiple essential oils; one person also reacted to swallowed lemongrass tea
oil / leaf tea Occupational exposure
Four cases of allergic contact dermatitis, mostly on the hands, each sensitised to several essential oils. One person's skin symptoms came back after swallowing lemongrass tea.
Case series; no rates.
Methods, limits and funding

Outcomes: Skin reactions, patch tests

Limitations: Four cases show it can happen, not how often. Reactions were in people with heavy occupational oil exposure.

Funding and conflicts: Not stated in the abstract

Read: abstract

Carmo 2013
Treatment of pityriasis versicolor with topical application of essential oil of Cymbopogon citratus (DC) Stapf - therapeutic pilot study
An Bras Dermatol · PMID 23793205 · DOI
Controlled trial
96
20 healthy volunteers (safety phase) and 76 people with pityriasis versicolor, a yeast skin infection (47 oil, 29 ketoconazole), Brazil
Lemongrass essential oil shampoo (3 times a week) and cream (twice a day) at 1.25 microlitres per mL
leaf (oil) 1.25 microlitres/mL, shampoo and cream 40 days · vs Same shampoo and cream with 2% ketoconazole
No significant adverse events in the 20-person safety phase. In the trial, 30 of 47 on the oil and 18 of 29 on ketoconazole finished. Mycological cure was 60% with the oil and over 80% with ketoconazole.
Cure 60% (oil) versus over 80% (ketoconazole), both P < 0.05 versus baseline.
Methods, limits and funding

Outcomes: Safety; mycological cure

Limitations: Pilot trial with about one third dropping out, no placebo, and the standard drug did better. Authors call for larger studies.

Funding and conflicts: No conflict of interest declared

Read: abstract

Chaisripipat 2015
Anti-dandruff Hair Tonic Containing Lemongrass (Cymbopogon flexuosus) Oil
Forsch Komplementmed · PMID 26566122 · DOI
Controlled trial
30
30 Thai volunteers aged 20-60 with dandruff
Hair tonic containing East Indian lemongrass (Cymbopogon flexuosus) essential oil at 5%, 10% or 15%
leaf (oil) Tonic twice a day, 5/10/15% oil 14 days (checked at day 7 and day 14) · vs Placebo tonic, split-head design
Dandruff fell by 33%, 75% and 51% at day 7 with 5%, 10% and 15% oil, and by 52%, 81% and 74% at day 14. The 10% tonic did best.
P < 0.005 for all strengths at both times (reductions as listed).
Methods, limits and funding

Outcomes: Dandruff score (D-Squame scale)

Limitations: Only 30 people, 2 weeks, a different species (C. flexuosus, not C. citratus), done by a cosmetic-science school; no follow-up after stopping.

Funding and conflicts: Not stated in the abstract

Read: abstract

Chawla 2025
Comparative evaluation of effectiveness among various sensory distractors for reducing dental anxiety in pediatric population aged 6-9 years - A randomized controlled trial
J Indian Soc Pedod Prev Dent · PMID 40159612 · DOI
Controlled trial
350
350 children aged 6 to 9 having dental treatment, India (70 per group)
Lemongrass oil aromatherapy as one of five distraction methods
leaf (oil; not stated) Not given in the abstract During one dental treatment · vs Four other distraction methods (cards, music, acupressure, honey taste); no stated no-treatment group
All five methods lowered anxiety scores. Music had the biggest effect and visual distraction was next. The authors say the smell (lemongrass) and taste (honey) methods were less effective than music and visuals.
All methods P < 0.001 before versus after; music mean change 1.10, visual 1.04; the lemongrass group's number is not given in the abstract.
Methods, limits and funding

Outcomes: Anxiety scale (Chota Bheem Chutki Scale), pulse, oxygen saturation

Limitations: Lemongrass was only one of five comparison arms; the abstract gives no figure for it and no group without any distraction, so it cannot show lemongrass itself caused the drop.

Funding and conflicts: Not stated in the abstract

Read: abstract

EFSA FEEDAP Panel (Bampidis 2023
Safety and efficacy of a feed additive consisting of an essential oil derived from the aerial parts of Cymbopogon flexuosus (Nees ex Steud.) Will. Watson (lemongrass oil) for use in all animal species (FEFANA asbl)
EFSA Journal · PMID 37502018 · DOI
Regulatory scientific opinion (animal feed additive)
animal/regulatory
Animal species (feed additive assessment); not a human study Lemongrass oil (Cymbopogon flexuosus)
aerial parts, essential oil
The panel judged the oil safe in feed up to species-specific levels (lowest calculated safe level, 33 mg/kg complete feed, for cats and for other species). It concluded the oil should be treated as an irritant to skin and eyes and as a dermal and respiratory sensitiser. No concerns for consumers were found at the highest safe feed level.
Methods, limits and funding

Outcomes: Safety for animals, consumers and environment; hazard class of the oil

Limitations: Feed-additive opinion, so its numbers are for animal feed and say nothing about diffusers or skin products. It assessed C. flexuosus oil.

Funding and conflicts: Regulatory panel; no industry funding stated in the abstract (the application came from a feed-additive trade association).

Read: abstract

Ekpenyong 2015
Ethnopharmacology, phytochemistry, and biological activities of Cymbopogon citratus (DC.) Stapf extracts
Chin J Nat Med · PMID 25986281 · DOI
Narrative review
mixed
Review Lemongrass extracts and essential oil
leaf / oil
The review says lemongrass oil compounds are absorbed quickly after oral, lung and skin exposure and are altered in the body by oxidation, glucuronidation, sulfation and methylation, then leave in urine, faeces and breath. It says reliable human pharmacokinetic data are lacking.
Narrative.
Methods, limits and funding

Outcomes: Pharmacology and pharmacokinetics

Limitations: Narrative review by authors who also ran the 2015 tea trials.

Funding and conflicts: Not stated in the abstract

Read: abstract

Elson 1989
Impact of lemongrass oil, an essential oil, on serum cholesterol
Lipids · PMID 2586227 · DOI
Uncontrolled trial
22
22 people with high cholesterol (about 315 mg/dl), USA
Lemongrass oil capsule (oil rich in geraniol and citral)
leaf (oil) 140 mg a day 90 days
Across all 22, the average cholesterol change just missed significance (P < 0.06). People split into 14 who did not respond (changes of +2, +2 and -1 mg/dl at 30, 60, 90 days) and 8 who did (-25, -33 and -38 mg/dl). Six responders measured 90 days after stopping were back near their starting values (+8 mg/dl, not significant).
Responders -38 +/- 10 mg/dl at 90 days (P < 0.025); non-responders -1 +/- 6 mg/dl; whole group P < 0.06.
Methods, limits and funding

Outcomes: Serum cholesterol

Limitations: No placebo group, 22 people, 1989, and splitting people into responders afterwards can exaggerate a result. The overall result was not significant.

Funding and conflicts: University and research-support funding; details not in the abstract

Read: abstract

European Medicines Agency 2026
EMA/HMPC herbal monograph search for Cymbopogon citratus
Web search 2026-10-25 · Source
Authoritative guidance
Not applicable Lemongrass (Cymbopogon citratus)
unspecified
A web search found no EMA/HMPC monograph on Cymbopogon citratus. The EMA site search could not be read directly (HTTP 401).
Methods, limits and funding

Outcomes: Identity, regulatory status or safety statements

Limitations: Not verified: absence in a web search is not proof that no EMA document exists.

Read: summary-only

Faridah 2026
Effectiveness of mosquito repellents for human: A systematic review of human-based studies
Acta Tropica · PMID 42285396 · DOI
Systematic review
19
19 human studies (2015 to 2025) of repellents
Mosquito repellents including essential oils (citronella, lemon eucalyptus, neem, lemongrass)
mixed products
DEET products usually protected longest (often five to nine hours). Natural repellents based on oils such as citronella, lemon eucalyptus, neem and lemongrass usually reached shorter complete protection, commonly two to four hours; some microencapsulated or nanoemulsion formulations did better.
Methods, limits and funding

Outcomes: Complete protection time, repellency rate

Limitations: Lemongrass was one of several oils pooled in the sentence; the abstract gives no lemongrass-only figure. Methods varied too much to combine (described descriptively).

Funding and conflicts: Not stated in the abstract.

Read: abstract

Fradin 2002
Comparative efficacy of insect repellents against mosquito bites
New England Journal of Medicine · PMID 12097535 · DOI
Controlled laboratory comparison in volunteers
15
15 volunteers in a controlled mosquito room
Seven botanical repellents, DEET products, IR3535, wristbands and a moisturiser (the abstract does not name the botanical oils)
mixed products
DEET protected longest (23.8% DEET: mean 301.5 minutes). A soybean-oil repellent averaged 94.6 minutes. All other botanical repellents protected for under 20 minutes on average. The authors say non-DEET products cannot be relied on for prolonged protection where mosquito-borne disease is a threat.
Methods, limits and funding

Outcomes: Complete protection time from mosquito bites

Limitations: The abstract does not say which botanical oils were tested, so it cannot be tied to lemongrass; one lab setting; 2002 products.

Funding and conflicts: Not stated in the abstract.

Read: abstract

GBIF Secretariat 2026
GBIF Backbone Taxonomy: Cymbopogon citratus (DC.) Stapf
GBIF API, checked 2026-10-25 · Source
Database record
Not applicable Lemongrass (Cymbopogon citratus)
unspecified
Accepted species, key 2705275, family Poaceae, order Poales, authority (DC.) Stapf, Bull. Misc. Inform. Kew 1906: 322; synonyms include Andropogon citratus DC.
Methods, limits and funding

Outcomes: Identity, regulatory status or safety statements

Limitations: Database entry; synonym list shown is the first ten returned by the API.

Read: full-text

GBIF Secretariat 2026
GBIF Backbone Taxonomy: Cymbopogon flexuosus, C. nardus and C. winterianus
GBIF API, checked 2026-10-25 · Source
Database record
Not applicable Lemongrass (Cymbopogon citratus)
unspecified
Cymbopogon flexuosus (Nees ex Steud.) W.Watson (key 8571291), C. nardus (L.) Rendle (key 2705267) and C. winterianus Jowitt ex Bor (key 2705273) are separate accepted species in the same genus and family.
Methods, limits and funding

Outcomes: Identity, regulatory status or safety statements

Limitations: Database entries.

Read: full-text

Geier 2022
Contact sensitization to essential oils: IVDK data of the years 2010-2019
Contact Dermatitis · PMID 35417610 · DOI
Observational
10930
10,930 dermatitis patients patch tested with essential oils at German-speaking skin clinics, 2010-2019
Twelve essential oils including lemongrass oil, patch test
oil Patch-test concentrations not in the abstract
908 patients (8.3%) reacted to at least one oil. Lemongrass oil gave 2.6% positive patch tests, second only to ylang ylang (3.9%) among the 12 oils. Masseurs and cosmeticians were over-represented.
Lemongrass oil 2.6% positive.
Methods, limits and funding

Outcomes: Percentage with a positive patch test

Limitations: Patients were already seen for dermatitis, so rates are higher than in the general public. Positive patch tests show allergy, not how common it is in ordinary users.

Funding and conflicts: Not stated in the abstract

Read: abstract

Goes 2015
Effect of Lemongrass Aroma on Experimental Anxiety in Humans
J Altern Complement Med · PMID 26366471 · DOI
Controlled trial
40
Forty healthy male volunteers, Brazil
Lemongrass (Cymbopogon citratus) essential oil, inhaled
leaf (oil; plant part not stated in abstract) 3 or 6 drops, inhaled once Single brief exposure, then a stress test (Stroop Color-Word Test) · vs Tea tree essential oil (3 drops) or distilled water (3 drops)
People who inhaled lemongrass (3 or 6 drops) reported lower state anxiety and tension straight after inhaling, and recovered from the stress test within 5 minutes, unlike the control groups. Body measures (heart rate, muscle activity) were not protected by any treatment.
Statistically significant versus controls for state anxiety and subjective tension; numbers not given in the abstract.
Methods, limits and funding

Outcomes: State anxiety, subjective tension, tranquilization, sedation, heart rate, muscle activity (EMG)

Limitations: Forty young men, single exposure, lab stress test rather than a clinical anxiety disorder, short follow-up. Control aroma was tea tree, which has its own smell, and blinding to smell is difficult. Authors say clinical relevance is unclear.

Funding and conflicts: Not stated in the abstract

Read: abstract

Junior 2024
Influence of Lemongrass Essential Oil (Cymbopogon flexuosus) Supplementation on Diabetes in Rat Model
Life (Basel) · PMID 38541661 · DOI
Animal research
animal
Male Wistar rats with streptozotocin-induced type 1 diabetes East Indian lemongrass (Cymbopogon flexuosus) essential oil (72.6% citral) and citral
leaf (oil) 32 or 64 mg/kg oil; 32 mg/kg citral 14 days · vs Vehicle (Tween solution)
The oil lessened the rise in blood sugar, abnormal blood fats and liver-enzyme changes caused by diabetes in these rats. Its main compounds were alpha-citral (53.21%) and neral (19.42%).
Described as a mitigating effect; numbers not in the abstract.
Methods, limits and funding

Outcomes: Blood sugar, lipids, antioxidant markers, ALT, AST

Limitations: Rat model of type 1 diabetes, two weeks, different species from C. citratus.

Funding and conflicts: Authors declare no conflicts of interest

Read: abstract

Katsukawa 2010
Citral, a component of lemongrass oil, activates PPARalpha and gamma and suppresses COX-2 expression
Biochim Biophys Acta · PMID 20656057 · DOI
Laboratory research
in-vitro
Cell lines (human macrophage-like U937 cells) Lemongrass oil and citral
oil Cell doses Cell assays · vs Untreated cells
Citral switched on two fat-handling and inflammation-control switches (PPAR alpha and gamma) and lowered COX-2 (an inflammation enzyme) in cells.
Dose-dependent suppression of COX-2 in cells.
Methods, limits and funding

Outcomes: COX-2 activity, PPAR activation

Limitations: Cell work only; does not show an effect in people.

Funding and conflicts: Not stated in the abstract

Read: abstract

Kumboyono 2026
Randomized Controlled Trial of a Nicotine Dependence Intervention: Evaluating the Efficacy of a Lemongrass (Cymbopogon citratus) Inhaler via Modulation of Nicotinic Acetylcholine Receptors
Current Pharmaceutical Biotechnology · PMID 42283179 · DOI
Randomized controlled trial (pretest posttest)
100
Adult smokers aged 18 to 30 with moderate-to-high nicotine dependence (FTND 5 or more)
Lemongrass essential oil 3% inhaler versus placebo inhaler
essential oil (aroma)
Four times daily for eight weeks, the lemongrass group had a larger fall in FTND score than placebo (mean difference 2.3, p<0.001) and in the serum receptor marker (0.6 ng/mL, p=0.003). The authors call this a large treatment effect and suggest it as an adjunct to smoking-cessation methods.
Methods, limits and funding

Outcomes: Fagerstrom nicotine dependence score (FTND); serum nicotinic receptor levels (ELISA)

Limitations: One abstract-only report; the receptor blood marker is an unusual outcome, no smoking abstinence outcome is described, the effect is very large for a scent, and no replication was found. The authors call for longer follow-up.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Kusuma 2024
Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review
Pharmaceuticals (Basel) · PMID 38399374 · DOI
Scoping review
8
8 clinical articles (2013 to 2022), mostly oromucosal and topical treatment
Lemongrass essential oil
aerial parts, essential oil
The authors say the oil might be useful for periodontitis, gingivitis and oral malodour, with similar effect to chlorhexidine (gingivitis) and doxycycline (periodontitis), and for pityriasis versicolor; it may have anti-dandruff effects. They call for more research on efficacy, safety, interactions and long-term tolerability.
Methods, limits and funding

Outcomes: Gingivitis, periodontitis, oral malodour, pityriasis versicolor, skin ageing, dandruff

Limitations: A scoping review maps studies and does not weigh their quality. Only 8 articles; the abstract gives no numbers.

Funding and conflicts: Not stated in the abstract.

Read: abstract

Lalko 2008
Citral: identifying a threshold for induction of dermal sensitization
Regul Toxicol Pharmacol · PMID 18353514 · DOI
Review
Review of human and animal skin-sensitisation data on citral Citral (main compound of lemongrass oil)
oil compound Human no-effect level 1400 micrograms per cm2 of skin
From a weight-of-evidence review the authors put the human no-observed-effect level for inducing skin sensitisation to citral at 1400 micrograms per cm2.
Human NOEL 1400 micrograms/cm2.
Methods, limits and funding

Outcomes: Threshold for induction of skin allergy

Limitations: Authors work for the fragrance industry body (RIFM), and the figure is for citral, not whole lemongrass oil.

Funding and conflicts: Industry-linked: authors are at the Research Institute for Fragrance Materials

Read: abstract

Maybodi 2025
Effect of aromatherapy with lemongrass (Cymbopogon citratus) on the anxiety of patients undergoing scaling and root planning: a randomized clinical trial
BMC Complement Med Ther · PMID 40069670 · DOI
Controlled trial
38
38 dental patients having non-surgical gum treatment (scaling and root planing), Yazd, Iran
Lemongrass essential oil aroma, inhaled during treatment
leaf (oil; plant part not stated in abstract) Not given in the abstract One treatment session · vs Same treatment with no aroma (no placebo aroma)
The lemongrass group had lower systolic and diastolic blood pressure, lower heart rate and lower anxiety scores than the no-aroma group. Oxygen saturation, pain and satisfaction did not differ.
Significant reductions in systolic and diastolic blood pressure, heart rate and anxiety score; numbers not given in the abstract.
Methods, limits and funding

Outcomes: Spielberger anxiety score, blood pressure, heart rate, oxygen saturation, pain, satisfaction

Limitations: Very small trial, one session, the comparison group got no aroma at all so people could tell which group they were in, anxiety is self-rated. The blood pressure change is a short-term reaction in nervous patients, not a treatment for high blood pressure.

Funding and conflicts: Authors declare no competing interests

Registration: IRCT20230615058492N2

Read: abstract

NCBI 2026
NCBI Taxonomy: Cymbopogon citratus (taxid 66014)
NCBI Taxonomy, checked 2026-10-25 · Source
Database record
Not applicable Lemongrass (Cymbopogon citratus)
unspecified
Species rank, taxid 66014, GenBank common name 'lemon grass', family Poaceae, genus Cymbopogon.
Methods, limits and funding

Outcomes: Identity, regulatory status or safety statements

Limitations: Database entry.

Read: full-text

NCBI PubChem 2026
PubChem compound records (citral/geranial, neral, geraniol, myrcene, limonene, citronellal)
PubChem PUG REST, checked 2026-10-25 · Source
Database record
in-vitro
Not applicable Lemongrass (Cymbopogon citratus)
unspecified
CIDs confirmed by name lookup: citral/geranial 638011, neral 643779, geraniol 637566, beta-myrcene 31253, limonene 22311, citronellal 7794.
Methods, limits and funding

Outcomes: Identity, regulatory status or safety statements

Limitations: Name lookup only; the lookup of the name 'geranial' returns the same CID as 'citral' (638011).

Read: full-text

NCCIH 2020
Aromatherapy
nccih.nih.gov/health/aromatherapy, last updated January 2020, read 2026-10-25 · Source
Authoritative guidance
n/a
General public Aromatherapy (essential oils) in general
NCCIH says essential oils are most often inhaled or applied in diluted form to the skin. It says whether aromatherapy helps insomnia is unknown because little rigorous research exists, and describes one study where lemon and lavender scents did not change stress indicators. Lemongrass is not named.
Methods, limits and funding

Outcomes: Definition of aromatherapy and evidence statements

Limitations: Short general page from 2020; it does not discuss lemongrass.

Read: full-text

NCCIH 2026
NCBI/NCCIH Herbs at a Glance list (checked for lemongrass)
nccih.nih.gov/health/herbsataglance, checked 2026-10-25 · Source
Authoritative guidance
Not applicable Lemongrass (Cymbopogon citratus)
unspecified
The NCCIH Herbs at a Glance page loaded (it lists Echinacea, Ginkgo, Turmeric) and has no lemongrass entry; the address /health/lemongrass returned 404.
Methods, limits and funding

Outcomes: Identity, regulatory status or safety statements

Limitations: Absence from a list is not an endorsement or a warning. Checked by text search of the page.

Read: full-text

NIDDK LiverTox 2026
LiverTox: Lemongrass (not read)
NCBI Bookshelf · Source
Authoritative guidance
Not applicable Lemongrass (Cymbopogon citratus)
unspecified
The LiverTox page could not be opened (the NCBI site showed a bot check). Its content was not read.
Methods, limits and funding

Outcomes: Identity, regulatory status or safety statements

Limitations: Not verified.

Read: summary-only

National Institute of Child Health and Human Development 2026
Lemongrass (Drugs and Lactation Database, LactMed)
LactMed, NCBI Bookshelf (revised 2026-10-15) · PMID 42903793
Authoritative guidance
Breastfeeding mothers and infants (database entry) Lemongrass (C. citratus) and its essential oil
leaf / oil
LactMed says lemongrass is in some mixtures promoted to raise milk supply but no scientifically valid trials support this. It says lemongrass essential oil extract is generally recognised as safe (GRAS) in foods by the US FDA, that rare cases of liver toxicity and allergic sensitisation have occurred with lemongrass, and describes two aromatherapists who became allergic and one whose rash returned after lemongrass tea and Thai food. It also describes raised liver enzymes in a woman taking Mother's Milk Tea, which contains West Indian lemongrass leaf.
Narrative database entry; only the PubMed record text was read, not the full entry.
Methods, limits and funding

Outcomes: Use in lactation, safety statements

Limitations: Only the PubMed summary of the record was read. The liver case involved a multi-herb tea, so lemongrass cannot be singled out. 'Rare' is LactMed's wording; no frequency is given.

Funding and conflicts: US government database

Read: abstract

Pet Poison Helpline 2026
Essential oils (Pet Poison Helpline)
petpoisonhelpline.com, read 2026-10-25 · Source
Authoritative guidance
n/a
Pets Essential oils in general (lemongrass is not named in the text read)
Essential oil poisoning can affect all species, but cats and birds are at greatest risk. Common signs include drooling, vomiting, lethargy, loss of appetite and irritation of the airways, skin and mouth, and signs usually appear within 6 to 8 hours. Owners should read labels and note the oil concentration.
Methods, limits and funding

Outcomes: Pet toxicity statements

Limitations: General statement for essential oils; no lemongrass-specific figures, no date shown.

Read: full-text

Poison Control (America's Poison Centers) 2026
Essential oils: Poisonous when misused
poison.org/articles/essential-oils, read 2026-10-25 · Source
Authoritative guidance
n/a
General public Essential oils in general (lemongrass is not named in the text read)
Poison Control says many essential oils can cause rashes on the skin and some are poisonous if absorbed through skin or swallowed; that breathing swallowed oil into the lungs can cause pneumonia; that children have thin skin and immature livers and so may be more susceptible; that essential oils may interact with medicines; that diluting in a carrier oil is the best way to avoid a bad reaction; and not to use oils on damaged skin. It describes an 18-month-old made drowsy and confused by a small amount of lavender extract. Store oils where children and pets cannot reach them.
Methods, limits and funding

Outcomes: Poisoning, skin, allergy and child safety statements

Limitations: General advice for essential oils; it does not name lemongrass, give lemongrass case numbers or date the page.

Read: full-text

Rosol 2023
FEMA GRAS assessment of natural flavor complexes: Lemongrass oil, chamomile oils, citronella oil and related flavoring ingredients
Food Chem Toxicol · PMID 36870670 · DOI
Authoritative guidance
Safety evaluation of flavour ingredients Natural flavour complexes from Cymbopogon and other genera (lemongrass oil among 23)
oil Flavour-use levels
An expert panel of the flavour industry association affirmed 23 natural flavour complexes, including ones from Cymbopogon, as GRAS under their intended conditions of use as flavourings. The scope does not include dietary supplements or products other than food.
GRAS affirmed for flavour use.
Methods, limits and funding

Outcomes: Generally recognised as safe (GRAS) status for use as flavouring

Limitations: Industry-panel opinion (FEMA), covers flavour amounts in food only; not a statement about supplements, medicinal doses or swallowing the oil.

Funding and conflicts: Industry-linked: panel members belong to FEMA and some authors are employed by a firm that supports FEMA

Read: abstract

Sari 2025
The effect of ginger essential oil, lemongrass essential oil and combination of ginger and lemongrass essential oils on symptoms of menopausal women
Afr J Reprod Health · PMID 41051148 · DOI
Controlled trial
355
Menopausal women at a public health centre, Padang, Indonesia
Aromatherapy with ginger oil, lemongrass oil, or both
oil (plant parts not stated) 20-minute session daily 4 weeks · vs No separate no-aroma group described in the abstract
All three aroma groups had lower menopausal symptom scores after 4 weeks.
Statistically significant reductions in all three arms; numbers not given in the abstract. The abstract says 355 women but also 89 per arm (3 x 89 = 267), so the true size is unclear.
Methods, limits and funding

Outcomes: Menopause Assessment Scale symptom score

Limitations: Numbers in the abstract do not add up, no no-treatment comparison is described, the combination arm mixes in ginger, and symptom scales are self-rated.

Funding and conflicts: Authors declare no conflict of interest

Read: abstract

Satthanakul 2015
Antimicrobial effect of lemongrass oil against oral malodour micro-organisms and the pilot study of safety and efficacy of lemongrass mouthrinse on oral malodour
J Appl Microbiol · PMID 25327222 · DOI
Controlled trial
20
20 healthy volunteers, Thailand
Lemongrass oil mouthrinse
leaf (oil) Concentration not given in the abstract 8 days · vs Randomised double-blind comparison (comparator not named in the abstract)
The rinse reduced bad-breath gases on day 8 and looked safe. In dish tests it was active against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis and less active against Streptococcus mutans. Volunteers found the spicy taste a drawback.
Significant reduction in volatile sulphur compounds on day 8; numbers not in the abstract.
Methods, limits and funding

Outcomes: Volatile sulphur compounds (bad-breath gases) by Halimeter; lab killing of mouth bacteria

Limitations: Pilot, 20 healthy people, 8 days.

Funding and conflicts: Not stated in the abstract

Read: abstract

Sharma 2021
Chemical Properties and Therapeutic Potential of Citral, a Monoterpene Isolated from Lemongrass
Med Chem · PMID 31880247 · DOI
Narrative review
mixed
Review Citral
oil compound
The review puts citral at roughly 65-85% of lemongrass oil. It says swallowed citral is fully digested in the gut and leaves metabolites including a number of acids and a biliary glucuronide, and that citral is unstable in air. It says there is no scientific evidence on long-term bioavailability.
Narrative.
Methods, limits and funding

Outcomes: Chemistry, metabolism

Limitations: Narrative review; abstract only.

Funding and conflicts: Not stated in the abstract

Read: abstract

Silva 2010
Comparative anticonvulsant activities of the essential oils (EOs) from Cymbopogon winterianus Jowitt and Cymbopogon citratus (DC) Stapf. in mice
Naunyn Schmiedebergs Arch Pharmacol · PMID 20237771 · DOI
Animal research
animal
Male Swiss mice; human neutrophils in the dish Essential oils of C. citratus and C. winterianus, injected into the belly
leaf (oil) 50, 100, 200 mg/kg intraperitoneal Acute · vs Vehicle and diazepam
Both oils delayed seizures and lengthened barbiturate sleep; lemongrass oil was stronger. Effects were blocked by flumazenil, which points to the GABA (calming) system. Both oils blocked release of the inflammation marker MPO from human white cells in the dish. A low dose of oil added to a low dose of diazepam increased the effect.
Reported as significant; numbers not in the abstract.
Methods, limits and funding

Outcomes: Seizure latency, barbiturate sleeping time, MPO and LDH release from human neutrophils

Limitations: Injected, not swallowed; animal and test-tube work.

Funding and conflicts: Not stated in the abstract

Read: abstract

Subha 2017
Periodontal Therapy with 0.25% Lemongrass Oil Mouthwash in Reducing Risk of Cardiovascular Diseases: A 3-Arm Prospective Parallel Experimental Study
Ethiop J Health Sci · PMID 29217959 · DOI
Controlled trial
45
45 people with severe gum disease (periodontitis), India (15 per group)
0.25% lemongrass oil mouthwash
leaf (oil) 0.25% oil 3 months · vs 0.12% chlorhexidine; cleaning only
In the lemongrass group CRP, pocket depth, attachment loss, total cholesterol and LDL fell compared with their own starting values. Between groups, only pocket depth and attachment loss differed (lemongrass and chlorhexidine each better than cleaning alone).
Within-group falls in CRP, total cholesterol and LDL; between-group differences significant for pocket depth and attachment loss only. Numbers not in the abstract.
Methods, limits and funding

Outcomes: Pocket depth, attachment loss, CRP, total cholesterol, HDL, LDL, triglycerides

Limitations: 15 per group; blood-marker drops within one group do not show a real effect against the other groups. The authors' heart-risk wording goes beyond what the between-group results show.

Funding and conflicts: Not stated in the abstract

Read: abstract

Tisserand Institute 2026
Safety guidelines (Tisserand Institute)
tisserandinstitute.org, read 2026-10-25 · Source
Professional guidance
n/a
General public Essential oils; lemongrass named as an oil more likely to cause skin reactions
The institute says not to apply undiluted essential oils to the skin, and that some oils, such as lemongrass, clove or cinnamon bark, are more likely to cause skin reactions than others. It advises seeing a doctor or suitable practitioner before using pure essential oils if you have a skin condition, are pregnant, have epilepsy or asthma, or take prescribed medicines. Undiluted oil must not go in the eyes (chemical burn).
Methods, limits and funding

Outcomes: Skin safety statements

Limitations: The page has an age-based dilution table, but its figures could not be read as text, so none are given here. The Tisserand Institute is an aromatherapy education body, not a regulator; no date shown.

Read: full-text

Uter 2010
Contact allergy to essential oils: current patch test results (2000-2008) from the Information Network of Departments of Dermatology (IVDK)
Contact Dermatitis · PMID 20946456 · DOI
Observational
15682
15,682 dermatitis patients patch tested with essential oils, 2000-2008
Essential oils including lemongrass oil, patch test
oil Not in the abstract
637 patients reacted to at least one oil. Lemongrass oil gave a weighted mean of 1.8% positive tests, behind ylang-ylang (3.1%).
Lemongrass oil 1.8% positive.
Methods, limits and funding

Outcomes: Percentage with a positive patch test

Limitations: Same limits as the later IVDK report: clinic patients, not the general public.

Funding and conflicts: Not stated in the abstract

Read: abstract

Wasey 2023
Comparative Evaluation of 0.25% Lemongrass Oil Mouthwash and 0.2% Chlorhexidine Mouthwash in Fixed Orthodontic Patients Suffering from Gingivitis
J Contemp Dent Pract · PMID 37534506 · DOI
Controlled trial
60
60 orthodontic patients with mild-to-moderate gum inflammation, India
0.25% lemongrass oil mouthwash, swished twice a day with brushing
leaf (oil) 0.25% oil, twice daily 21 days · vs 0.2% chlorhexidine mouthwash; oral cleaning only
Plaque and gum scores were lower with lemongrass oil than with chlorhexidine at day 14 and day 21 (P < 0.001).
P < 0.001 versus chlorhexidine; scores not given in the abstract.
Methods, limits and funding

Outcomes: Plaque index and gingival index

Limitations: Three groups of 20, 3 weeks, small and from one setting. A result better than the standard mouthwash is unusual and needs repeating by independent teams.

Funding and conflicts: Not stated in the abstract

Read: abstract

de Groot 2016
Essential Oils, Part V: Peppermint Oil, Lavender Oil, and Lemongrass Oil
Dermatitis · PMID 27775966 · DOI
Narrative review
Review Lemongrass oil among three oils
oil
The review covers contact allergy and allergic contact dermatitis from lemongrass oil and the causative allergenic ingredients. The abstract gives no numbers.
Not given in the abstract.
Methods, limits and funding

Outcomes: Contact allergy and allergenic ingredients

Limitations: Only the short abstract was read.

Funding and conflicts: Not stated in the abstract

Read: abstract

What we do not know yet

  • What the evidence supports: low for dandruff, a yeast skin infection and mosquito repellency; very low for scent and anxiety and mouth products; insufficient for menopause and nicotine.
  • No safe skin dilution for lemongrass oil was verified from a readable source, so none is given.
  • No lemongrass-specific source on poisoning, pets, pregnancy, babies, glaucoma or prostate problems.
  • No human interaction study with any medicine.
  • No LiverTox, EMA monograph or full LactMed page was read.

How new research is added

New studies are found by a saved PubMed search and are placed in a review queue. A person reads each one before it is added.

Lab markers

What changed in blood or saliva tests during trials. A changed number is not the same as feeling or being healthier, and we give no "normal ranges".

Metabolic 1

↕

Total cholesterol

Mixed results in trials

The total amount of cholesterol in the blood.

Very low certainty
Results and what it means

Why it was measured

Standard heart-risk marker.

Statistical vs. clinical meaning

No placebo group in the main study; results inconsistent.

Safety implication

None specific.

StudyResultPeopleProduct
9Overall change approached significance (P < 0.06); 8 responders fell 25, 33, 38 mg/dl at 30, 60, 90 days; 14 non-responders +2, +2, -1 mg/dl22 people with cholesterol about 315 mg/dlLemongrass oil 140 mg a day for 90 days
36Fell within the lemongrass mouthwash group; not significantly different between groups45 people with severe periodontitis0.25% lemongrass mouthwash, 3 months

9 36

Other 7

▼

State anxiety and tension (self-rated)

Lowered in trials

A questionnaire that scores how anxious a person feels right now. Lower is calmer.

Very low certainty
Results and what it means

Why it was measured

It is the main outcome in the scent anxiety trials.

Statistical vs. clinical meaning

Statistically significant in two small aroma trials; the size of change in everyday terms is not given in the abstracts.

Safety implication

None identified from this measure.

StudyResultPeopleProduct
16Lower state anxiety and subjective tension right after inhaling lemongrass oil (3 or 6 drops) than after tea tree oil or water; numbers not in the abstract40 healthy menLemongrass oil aroma, once
22Lower Spielberger anxiety scores with aroma than without during gum treatment; numbers not in the abstract38 dental patientsLemongrass oil aroma

16 22

↕

Heart rate

Mixed results in trials

Heartbeats per minute. Rises with stress.

Very low certainty
Results and what it means

Why it was measured

Used as a body sign of stress and calm.

Statistical vs. clinical meaning

One trial positive, one negative; both small.

Safety implication

Heart rate change in a nervous patient is not a treatment effect for heart disease.

StudyResultPeopleProduct
22Lower heart rate with lemongrass aroma than without during gum treatment; numbers not in the abstract38 dental patientsLemongrass oil aroma
16Heart rate response to the stress test was not prevented by lemongrass aroma40 healthy menLemongrass oil aroma, 3 or 6 drops

22 16

▼

Dandruff score (D-Squame scale)

Lowered in trials

A grade of how much scalp flaking there is, by pressing a tape on the scalp.

Low certainty
Results and what it means

Why it was measured

The main outcome of the hair-tonic trial.

Statistical vs. clinical meaning

Large statistical drops; clinical importance not stated.

Safety implication

Possible skin reactions to the oil; not reported in the abstract.

StudyResultPeopleProduct
5Dandruff reduced 33%, 75%, 51% at day 7 and 52%, 81%, 74% at day 14 with 5%, 10%, 15% lemongrass oil tonic30 Thai volunteers with dandruffC. flexuosus oil tonic twice a day

5

▼

Mycological cure (yeast cleared on lab culture)

Lowered in trials

Whether the yeast can no longer be grown from the skin.

Low certainty
Results and what it means

Why it was measured

Standard measure for skin fungal infections.

Statistical vs. clinical meaning

Lower than the standard drug; about a third dropped out.

Safety implication

Phase I found no significant adverse events.

StudyResultPeopleProduct
4Cure 60% with lemongrass oil formulations versus over 80% with ketoconazole after 40 days76 people with pityriasis versicolor (30 oil, 18 ketoconazole finished)Oil shampoo and cream versus ketoconazole versions

4

▼

Volatile sulphur compounds (bad-breath gases)

Lowered in trials

Gases made by mouth bacteria that cause bad breath, measured with a Halimeter.

Very low certainty
Results and what it means

Why it was measured

Objective measure of bad breath.

Statistical vs. clinical meaning

Small pilot.

Safety implication

Spicy taste; the rinse looked safe.

StudyResultPeopleProduct
33Significantly reduced on day 8 with the lemongrass rinse; numbers not in the abstract20 healthy volunteersLemongrass oil mouth rinse

33

▼

Plaque index and gingival (gum) index

Lowered in trials

Dentists' scores for how much plaque covers the teeth and how inflamed the gums are.

Very low certainty
Results and what it means

Why it was measured

Standard measures for gum health.

Statistical vs. clinical meaning

Small and unusually favourable to the herb.

Safety implication

None reported in the abstract.

StudyResultPeopleProduct
39Lower plaque and gum scores than chlorhexidine at day 14 and day 21 (P < 0.001); scores not in the abstract60 braces patients with gingivitis0.25% lemongrass oil mouthwash versus 0.2% chlorhexidine

39

●

Complete protection time (time before the first mosquito bite)

Increase in trials

How long a repellent keeps all mosquitoes off treated skin.

Low certainty
Results and what it means

Why it was measured

Main outcome in repellent tests.

Statistical vs. clinical meaning

Measures bites avoided in a test, not illness prevented.

Safety implication

Where mosquito-borne disease is a risk, a longer-lasting registered repellent matters more than a plant oil.

StudyResultPeopleProduct
11Natural oil repellents (citronella, lemon eucalyptus, neem, lemongrass) usually two to four hours; DEET often five to nine hours.
12Most botanical repellents under 20 minutes on average; 23.8% DEET 301.5 minutes.

11 12

Safety

What studies and official sources say about side effects, medicines and who should check first. Each point shows what kind of evidence it comes from.

Main points to know 9
  • Lemongrass oil is a known skin allergen. Never put it on skin undiluted.. In skin clinics, 2.6% of 10,930 dermatitis patients patch tested between 2010 and 2019 reacted to lemongrass oil (1.8% in an earlier 15,682-patient series). Four case reports describe people who became allergic after heavy work exposure to essential oils. These people were already seen for skin problems, so the figures are not rates in ordinary users. EFSA says to treat the oil as an irritant to skin and eyes and as a skin and respiratory sensitiser. The Tisserand Institute lists lemongrass among oils more likely to cause skin reactions and says not to apply any essential oil undiluted. Observational 15 38 3 40 7 37
  • Do not swallow the essential oil, and keep it away from children. Poison Control says some essential oils are poisonous if swallowed, that swallowed oil breathed into the lungs can cause pneumonia, and that children may be more susceptible because their skin is thin and their livers are immature. It does not name lemongrass, and we found no poisoning report for lemongrass oil in the sources we could read. One 1989 study gave oil capsules to 22 adults and its abstract reported no side effects, but that does not make swallowing the oil safe. Food flavouring use is a different matter: an industry panel affirmed lemongrass oil as GRAS for flavour use. If anyone, especially a child, may have swallowed essential oil, call a poison centre (US 1-800-222-1222) or your emergency number. Authoritative guidance 30 9 31
  • Asthma and breathing: diffusing is not risk-free. EFSA says the oil should be treated as a respiratory sensitiser, meaning it may trigger breathing problems in people who become sensitised. That comes from a feed-additive review, not from diffuser studies in people. The Tisserand Institute advises seeing a doctor first if you have asthma or epilepsy. People with asthma or breathing problems should ask a clinician before diffusing it. Authoritative guidance 7 37
  • Pets, especially cats and birds. Pet Poison Helpline says essential oil poisoning can affect all species and that cats and birds are at greatest risk. The ASPCA lists the lemon grass plant as toxic to dogs, cats and horses. EFSA set a lower safe feed level for cats (33 mg/kg complete feed) than for dogs (50 mg/kg), but those are feed figures, not diffuser or skin figures. No source we read says lemongrass oil is safe for pets. Call a vet or an animal poison line if a pet is exposed. Authoritative guidance 29 1 7
  • Pregnancy, breastfeeding, babies and medicines: no lemongrass-specific answer. We found no source on lemongrass oil in pregnancy, in babies or in children, apart from general statements. Poison Control says children may be more susceptible and that essential oils may interact with medicines. The Tisserand Institute advises talking to a doctor first if you are pregnant or take prescribed medicines. LactMed says no valid trials support lemongrass for milk supply and mentions rare liver toxicity and allergic sensitisation. Ask a doctor or pharmacist before use. Authoritative guidance 30 37 28
  • Eyes, broken skin and the inner nose. The Tisserand Institute warns that undiluted essential oil in the eyes causes a chemical burn and may cause temporary blindness. Poison Control says not to use essential oils on damaged skin. Keep the oil away from both. Authoritative guidance 37 30
  • Sedative effects are shown only in mice. In mice, low doses of lemongrass oil strengthened diazepam and lengthened barbiturate sleep, and the effect was blocked by flumazenil, which points to the GABA calming system. No human interaction study was found. This was with injected or large oral doses, not scent. Animal research 35 2
  • Glaucoma and prostate: no lemongrass-specific statement found. We searched the sources we read for glaucoma and prostate cautions and found none that name lemongrass oil. Not described is not proof of none. People with glaucoma or prostate problems who are unsure should ask their doctor. Absence 37 30
  • Regulators: no medicine approval for the oil found. We found no EMA/HMPC monograph on lemongrass, no NCCIH lemongrass entry, and no FDA approval for the oil as a medicine. LactMed says the FDA treats the oil as GRAS in foods; an industry expert panel (FEMA) affirmed it as GRAS for flavour use only, excluding supplements. Authoritative guidance 10 26 28 31
Side effects 6
EffectHow oftenSeverity and recoveryEvidence
Allergic contact dermatitis (skin allergy) from lemongrass oil
Masseurs and cosmeticians were over-represented in one series. The percentages come from people already attending a dermatitis clinic and are not rates for the public.
2.6% of 10,930 patch-tested clinic patients (2010 to 2019); 1.8% of 15,682 (2000 to 2008)moderate
Not stated in the abstracts; sensitisation can last (general dermatology knowledge, not from a source read).
Observational 15 38 3 40
Skin and eye irritation from strong, undiluted oil
EFSA says to treat the oil as an irritant to skin and eyes. The hair tonic and shampoo trials did not report irritation in their abstracts.
Not establishedmild to moderate
Not stated
Authoritative guidance 7 37
Breathing symptoms in people who become sensitised
EFSA classes the oil as a respiratory sensitiser. No diffuser study in people was found.
Not establishedunknown
Not stated
Authoritative guidance 7
Spiciness and taste problems with a lemongrass oil mouth rinse
The trial found the rinse acceptable but said spiciness and taste needed improving.
Not establishedmild
Not applicable
Controlled trial 33
Pneumonia if swallowed oil is breathed into the lungs
A general statement about essential oils from Poison Control, not a lemongrass case report.
Not establishedserious
Not stated
Authoritative guidance 30
Rash returning after swallowing lemongrass in a person already allergic to oils
A person sensitised at work had a rash recurrence after taking lemongrass tea; LactMed describes the same. This is about swallowing, so it is a reason for care in people with oil allergy.
Not establishedmoderate
Not stated
Case series 3 28
Liver

We found no report of liver injury from lemongrass oil in the sources we could read. LactMed says rare cases of liver toxicity have occurred with lemongrass and describes raised liver enzymes in a woman taking a multi-herb milk-supply tea that included West Indian lemongrass leaf, so lemongrass cannot be singled out. Poison Control mentions that some essential oils are toxic to the liver but does not name lemongrass. LiverTox could not be opened. 28 30 27

How often. No frequency was found. The word rare is LactMed's own and no figure is given.

Monitoring. No agency monitoring advice was found. People with liver disease should ask a doctor before using any essential oil product.

This is a safety connection. It is not evidence that Lemongrass Oil supports liver health.

Medicines and supplements 4
WithWhy it mattersImportanceEvidenceWhat to do
Sedative medicines and herbs (benzodiazepines, barbiturates)
sedatives
Theory from mice: lemongrass oil strengthened diazepam and barbiturate sleep and flumazenil blocked the effect.No human interaction has been documented.Animal research Very low certainty 35 2If you take sedatives or sleep medicine, ask your doctor or pharmacist before using lemongrass oil other than as a passing scent.
Any medicine, in general
prescription
Poison Control says essential oils may interact with medicines.General statement; no lemongrass-specific interaction study was found.Authoritative guidance Not enough evidence 30 37Tell your pharmacist about all essential oils and herbs you use, especially if you take prescribed medicines.
Cytochrome P450 drug-processing enzymes
prescription
No study of lemongrass oil and these enzymes was found in the sources read.Unknown.Pharmacological theory Not enough evidence 8No advice can be given beyond telling your pharmacist what you use.
Other fragrance or essential-oil products you are allergic to
other
Cross-reaction: people allergic to citral or other fragrance ingredients may react to lemongrass oil. Patients in the IVDK data often reacted to more than one oil.Documented as patch-test results, not interactions between products.Observational Low certainty 15 38 21If you already have a fragrance or essential-oil allergy, avoid lemongrass oil and ask a dermatologist about patch testing.
Who should check first 9
SituationAdviceEvidence
Allergy to lemongrass, citral or other fragrance or essential-oil ingredients, or a past rash from a lemongrass productDo not use the oil. Seek medical advice.Observational 3 15
Swallowing the oil, especially by or near childrenDo not swallow. If a child or pet may have swallowed any essential oil, call poison control (US 1-800-222-1222) or your emergency number.Authoritative guidance 30
Asthma, breathing problems or epilepsyAsk a doctor before diffusing or using the oil (Tisserand Institute advice; EFSA lists the oil as a respiratory sensitiser).Authoritative guidance 37 7
PregnancyNo lemongrass-specific source was found. The Tisserand Institute advises seeing a doctor first. Ask a doctor or midwife.Authoritative guidance 37
BreastfeedingAsk a clinician. LactMed says no valid trials support lemongrass for milk supply and mentions rare liver toxicity and allergic sensitisation.Authoritative guidance 28
Babies and young childrenPoison Control says children may be more susceptible. Do not use the oil on or near babies without asking a doctor. An aroma was used in one trial of children aged 6 to 9 for one dental visit; nothing else is known.Authoritative guidance 30 6
Skin condition, open wounds or broken skinDo not apply the oil. Poison Control says not to use essential oils on damaged skin.Authoritative guidance 30 37
Eyes and the inner noseKeep the oil out. Undiluted oil in the eye can cause a chemical burn (Tisserand Institute).Authoritative guidance 37
Households with cats, birds or other petsPet Poison Helpline names cats and birds as most at risk from essential oils. Ask a vet before diffusing or applying any oil near pets.Authoritative guidance 29 1
Overdose, product quality and regulators

Summary. The concern is the concentrated oil (mostly citral), which is a skin allergen and irritant. We found no poisoning case report for lemongrass oil in the sources we could read.

Amounts. No safe amount is established, and this page gives none.

Onset and course. Not described for lemongrass oil. For pets, Pet Poison Helpline says signs usually appear within 6 to 8 hours with most essential oils.

Repeated use. Repeated skin contact is the setting for allergy in the patch-test series; heavy occupational exposure was linked with sensitisation.

Animal data. EFSA reviewed animal data for the oil as a feed additive and set safe feed levels by species, with the lowest calculated level for cats. A human skin-sensitisation no-effect level for citral of 1400 micrograms per cm2 was estimated by fragrance-industry scientists (not a safe-use figure for products).

Toxic parts. The essential oil, not the grass leaf, is the concentrated product. The ASPCA lists the lemon grass plant as toxic to dogs, cats and horses.

Not read. A poison-centre source naming lemongrass oil, a veterinary paper on lemongrass oil in cats, and the full EFSA opinion text were not read.

We found no study of contamination or adulteration of lemongrass oil. Essential oil products are not tightly regulated for medicinal use, and the oil of different Cymbopogon species varies.

Species mix-ups: C. citratus, C. flexuosus and citronella grasses. Several trials of lemongrass used Cymbopogon flexuosus (the dandruff and diabetic-rat studies), and citronella-type oil comes from different species and is rich in citronellal. Results from one cannot be assumed for another. 5 17 35

Oil is unstable in air. A review says citral breaks down on exposure to air. Old or oxidised oil may behave differently, and oxidised essential oils are a known allergy concern (general dermatology knowledge, not verified here). 34

Heavy metals, pesticides, adulteration. Not checked; no lemongrass-specific testing study was read.

BodyActionDate
EFSA FEEDAP Panel (EU) (European Union)Opinion on lemongrass oil (Cymbopogon flexuosus) as an animal feed additive: the oil should be considered an irritant to skin and eyes and a dermal and respiratory sensitiser. It set the lowest calculated safe feed level (33 mg/kg complete feed) for cats and other species. These feed figures do not apply to diffusers or skin use. source2023-07
Poison Control (America's Poison Centers) (United States)General essential-oil warnings: some oils are poisonous if swallowed or absorbed; swallowed oil breathed into the lungs can cause pneumonia; children may be more susceptible; oils may interact with medicines; dilute in a carrier oil and never use on damaged skin. Lemongrass is not named. source
LactMed (US National Library of Medicine) (United States)Lactation entry for lemongrass: no scientifically valid trials support lemongrass to raise milk supply; the essential oil extract is described as GRAS in foods per the FDA; rare liver toxicity and allergic sensitisation have occurred. source2026-10-15
FEMA Expert Panel (flavour industry association) (United States)Affirmed natural flavour complexes from Cymbopogon (including lemongrass oil) as GRAS for flavour use; the scope excludes dietary supplements. source2023-03
NCCIH (US National Center for Complementary and Integrative Health) (United States)No lemongrass entry in the Herbs at a Glance list. The NCCIH aromatherapy page (January 2020) is general and does not name lemongrass. source2020-01
When to get medical help
  • If anyone, especially a child, has swallowed lemongrass essential oil or any essential oil, or has choked on it: call a poison centre (US 1-800-222-1222) or your emergency number right away, even if they seem well.
  • Vomiting, drowsiness, confusion, breathing trouble or a seizure after swallowing an essential oil: emergency help now.
  • A widespread rash, swelling of the face or lips, wheezing or trouble breathing after using or smelling lemongrass oil: stop and get urgent medical help.
  • A red, itchy, blistering or weeping rash where the oil touched the skin: wash it off with soap and water, stop using it and see a doctor or pharmacist.
  • Oil in the eye: rinse with plenty of water and get medical help. A pet that drools, vomits, is very sleepy or has trouble breathing after exposure: call a vet or an animal poison line.

Stop using the product and contact a clinician or emergency service. In the US, Poison Control is 1-800-222-1222.

General information only, not medical advice. Ask a clinician or pharmacist before use, especially with medicines, in pregnancy or with a health condition. See the Natural Remedy Safety guide.

Frequently asked questions

Is lemongrass oil safe to swallow?

No. We do not advise swallowing essential oil. Poison Control warns that some essential oils are poisonous if swallowed and that oil breathed into the lungs can cause pneumonia. It does not name lemongrass, and we found no lemongrass poisoning report, but that is not proof of safety. If a child or pet may have swallowed any essential oil, call poison control (US: 1-800-222-1222) or your emergency number.

30

Can lemongrass oil cause a skin rash or allergy?

Yes. In a network of skin clinics, 2.6% of 10,930 patients patch tested between 2010 and 2019 had a positive test to lemongrass oil. These were people with skin problems, so the figure is not a rate for everyone. EFSA says to treat the oil as a skin irritant and sensitiser, and the Tisserand Institute says never to apply essential oil undiluted. Stop use and see a doctor or pharmacist if a rash appears.

15 38 7 37

Is lemongrass oil safe for cats and dogs?

We found no source saying it is safe. Pet Poison Helpline says essential oils can poison any pet, with cats and birds at greatest risk, and the ASPCA lists the lemon grass plant as toxic to dogs, cats and horses. Ask a vet before using any essential oil near pets, and call an animal poison line if a pet is exposed.

29 1 7

Is it safe in pregnancy or while breastfeeding?

We found no source on lemongrass oil in pregnancy. The Tisserand Institute advises seeing a doctor before using pure essential oils if you are pregnant. LactMed says no valid trials support lemongrass for milk supply and mentions rare liver toxicity and allergic sensitisation. Ask a doctor or midwife.

37 28

Is it safe for babies and children?

Poison Control says children have thin skin and immature livers and may be more susceptible to essential oils. We found no lemongrass-specific safety advice for babies. Keep the oil out of reach and ask a doctor before using it around babies. One trial used lemongrass scent for children aged 6 to 9 during a dental visit, with no wider safety finding.

30 6

Does lemongrass oil help anxiety?

Two small trials found lower anxiety scores while people breathed it during dental treatment or a lab stress test. Neither had a comparison scent that hid the oil, so expectation may play a part. In mice, large doses of oil were calming, which has not been tested in people. Certainty is very low, and it is not a treatment for anxiety disorders.

22 16 2

Does lemongrass oil help dandruff?

One small Thai trial of 30 people tested a hair tonic made with lemongrass oil (C. flexuosus) and reported less dandruff after two weeks. It was a made product, not plain oil, in a small group, and it has not been repeated. Certainty is low. This is not advice to put the oil on the scalp.

5 20

Does lemongrass oil repel mosquitoes?

For a short time, perhaps. A 2026 review said oil-based repellents (citronella, lemon eucalyptus, neem, lemongrass) usually protect two to four hours, less than DEET. A 2002 volunteer test found most botanical repellents protected under 20 minutes. Where mosquito-borne illness is a risk, the CDC recommends EPA-registered repellents.

11 12

Is lemongrass oil an antifungal?

In the lab and in small trials it has shown antifungal action. A pilot of an oil shampoo and cream for a yeast skin infection cleared about 60% of people who finished, compared with over 80% for a ketoconazole version, so the standard drug did better. Certainty is low.

4 20

Can I diffuse lemongrass oil if I have asthma?

Ask a clinician first. EFSA says the oil should be treated as a respiratory sensitiser, meaning it may trigger breathing problems in people who become sensitised. That comes from a feed-additive review, not from diffuser studies in people.

7 37

Does lemongrass oil interact with medicines?

No human interaction study was found. In mice the oil strengthened sedative drugs, and Poison Control says essential oils may interact with medicines in general. Tell your pharmacist about any essential oil you use, especially if you take sedatives or other prescribed medicines.

35 30

Is lemongrass oil the same as lemongrass tea or citronella oil?

No. Tea is a water extract of the leaf with little oil, and its findings (such as kidney effects in one 30-day study) do not describe the oil. Citronella oil comes from different grasses and has its own page. Results for one product should not be applied to another.

14 34

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Editorial transparency
Written by
AlternativeMed editorial team. Research compiled with AI assistance, then checked against PubMed records.
Medical review
None. This page has not been reviewed by a physician or pharmacist.
First published
2026-10-25
Last substantive update
2026-10-25
How we research
We read the abstracts of the PubMed papers listed, plus the Poison Control, Pet Poison Helpline, ASPCA, Tisserand Institute and NCCIH pages, checked plant names in GBIF and NCBI and compounds in PubChem. We could not read LiverTox or an EMA document.
How we rate evidence
See "How we rate evidence" in the Evidence tab.
Independence
No product is promoted on this page. No affiliate links are shown.
Sources 40

Each source was opened and checked. Where we read only the abstract, it says so. The small numbers in the text point here.

  1. ASPCA Animal Poison Control. Toxic and Non-toxic Plants: Lemon Grass. aspca.org, read 2026-10-25. 2026. (full-text)
  2. Blanco MM, Costa CA, Freire AO, et al.. Neurobehavioral effect of essential oil of Cymbopogon citratus in mice. Phytomedicine. 2009. PMID 17561386. DOI 10.1016/j.phymed.2007.04.007. (abstract)
  3. Bleasel N, Tate B, Rademaker M. Allergic contact dermatitis following exposure to essential oils. Australas J Dermatol. 2002. PMID 12121401. DOI 10.1046/j.1440-0960.2002.00598.x. (abstract)
  4. Carmo ES, Pereira FdO, Cavalcante NM, et al.. Treatment of pityriasis versicolor with topical application of essential oil of Cymbopogon citratus (DC) Stapf - therapeutic pilot study. An Bras Dermatol. 2013. PMID 23793205. DOI 10.1590/abd1806-4841.20131800. (abstract)
  5. Chaisripipat W, Lourith N, Kanlayavattanakul M. Anti-dandruff Hair Tonic Containing Lemongrass (Cymbopogon flexuosus) Oil. Forsch Komplementmed. 2015. PMID 26566122. DOI 10.1159/000432407. (abstract)
  6. Chawla T, Nangia T, Srivastava M, et al.. Comparative evaluation of effectiveness among various sensory distractors for reducing dental anxiety in pediatric population aged 6-9 years - A randomized controlled trial. J Indian Soc Pedod Prev Dent. 2025. PMID 40159612. DOI 10.4103/jisppd.jisppd_18_25. (abstract)
  7. EFSA FEEDAP Panel (Bampidis V, Azimonti G, et al). Safety and efficacy of a feed additive consisting of an essential oil derived from the aerial parts of Cymbopogon flexuosus (Nees ex Steud.) Will. Watson (lemongrass oil) for use in all animal species (FEFANA asbl). EFSA Journal. 2023. PMID 37502018. DOI 10.2903/j.efsa.2023.8180. (abstract)
  8. Ekpenyong CE, Akpan E, Nyoh A. Ethnopharmacology, phytochemistry, and biological activities of Cymbopogon citratus (DC.) Stapf extracts. Chin J Nat Med. 2015. PMID 25986281. DOI 10.1016/S1875-5364(15)30023-6. (abstract)
  9. Elson CE, Underbakke GL, Hanson P, et al.. Impact of lemongrass oil, an essential oil, on serum cholesterol. Lipids. 1989. PMID 2586227. DOI 10.1007/BF02535203. (abstract)
  10. European Medicines Agency. EMA/HMPC herbal monograph search for Cymbopogon citratus. Web search 2026-10-25. 2026. (summary-only)
  11. Faridah L, Nurhakim RA, Astuti RRUNW, et al. Effectiveness of mosquito repellents for human: A systematic review of human-based studies. Acta Tropica. 2026. PMID 42285396. DOI 10.1016/j.actatropica.2026.108182. (abstract)
  12. Fradin MS, Day JF. Comparative efficacy of insect repellents against mosquito bites. New England Journal of Medicine. 2002. PMID 12097535. DOI 10.1056/NEJMoa011699. (abstract)
  13. GBIF Secretariat. GBIF Backbone Taxonomy: Cymbopogon citratus (DC.) Stapf. GBIF API, checked 2026-10-25. 2026. (full-text)
  14. GBIF Secretariat. GBIF Backbone Taxonomy: Cymbopogon flexuosus, C. nardus and C. winterianus. GBIF API, checked 2026-10-25. 2026. (full-text)
  15. Geier J, Schubert S, Reich K, et al.. Contact sensitization to essential oils: IVDK data of the years 2010-2019. Contact Dermatitis. 2022. PMID 35417610. DOI 10.1111/cod.14126. (abstract)
  16. Goes TC, Ursulino FR, Almeida-Souza TH, et al.. Effect of Lemongrass Aroma on Experimental Anxiety in Humans. J Altern Complement Med. 2015. PMID 26366471. DOI 10.1089/acm.2015.0099. (abstract)
  17. Junior ASS, Aidar FJ, Silva LAS, et al.. Influence of Lemongrass Essential Oil (Cymbopogon flexuosus) Supplementation on Diabetes in Rat Model. Life (Basel). 2024. PMID 38541661. DOI 10.3390/life14030336. (abstract)
  18. Katsukawa M, Nakata R, Takizawa Y, et al.. Citral, a component of lemongrass oil, activates PPARalpha and gamma and suppresses COX-2 expression. Biochim Biophys Acta. 2010. PMID 20656057. DOI 10.1016/j.bbalip.2010.07.004. (abstract)
  19. Kumboyono K, Srihardyastutie A, Kumala YR, et al. Randomized Controlled Trial of a Nicotine Dependence Intervention: Evaluating the Efficacy of a Lemongrass (Cymbopogon citratus) Inhaler via Modulation of Nicotinic Acetylcholine Receptors. Current Pharmaceutical Biotechnology. 2026. PMID 42283179. DOI 10.2174/0113892010455442260522064407. (abstract)
  20. Kusuma IY, Perdana MI, Vagvolgyi C, et al. Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review. Pharmaceuticals (Basel). 2024. PMID 38399374. DOI 10.3390/ph17020159. (abstract)
  21. Lalko J, Api AM. Citral: identifying a threshold for induction of dermal sensitization. Regul Toxicol Pharmacol. 2008. PMID 18353514. DOI 10.1016/j.yrtph.2008.01.006. (abstract)
  22. Maybodi FR, Herandi V, Vaezpour MS. Effect of aromatherapy with lemongrass (Cymbopogon citratus) on the anxiety of patients undergoing scaling and root planning: a randomized clinical trial. BMC Complement Med Ther. 2025. PMID 40069670. DOI 10.1186/s12906-025-04834-w. (abstract)
  23. NCBI. NCBI Taxonomy: Cymbopogon citratus (taxid 66014). NCBI Taxonomy, checked 2026-10-25. 2026. (full-text)
  24. NCBI PubChem. PubChem compound records (citral/geranial, neral, geraniol, myrcene, limonene, citronellal). PubChem PUG REST, checked 2026-10-25. 2026. (full-text)
  25. NCCIH, National Institutes of Health. Aromatherapy. nccih.nih.gov/health/aromatherapy, last updated January 2020, read 2026-10-25. 2020. (full-text)
  26. NCCIH, National Institutes of Health. NCBI/NCCIH Herbs at a Glance list (checked for lemongrass). nccih.nih.gov/health/herbsataglance, checked 2026-10-25. 2026. (full-text)
  27. NIDDK LiverTox. LiverTox: Lemongrass (not read). NCBI Bookshelf. 2026. (summary-only)
  28. National Institute of Child Health and Human Development. Lemongrass (Drugs and Lactation Database, LactMed). LactMed, NCBI Bookshelf (revised 2026-10-15). 2026. PMID 42903793. (abstract)
  29. Pet Poison Helpline. Essential oils (Pet Poison Helpline). petpoisonhelpline.com, read 2026-10-25. 2026. (full-text)
  30. Poison Control (America's Poison Centers). Essential oils: Poisonous when misused. poison.org/articles/essential-oils, read 2026-10-25. 2026. (full-text)
  31. Rosol TJ, Cohen SM, Eisenbrand G, et al.. FEMA GRAS assessment of natural flavor complexes: Lemongrass oil, chamomile oils, citronella oil and related flavoring ingredients. Food Chem Toxicol. 2023. PMID 36870670. DOI 10.1016/j.fct.2023.113697. (abstract)
  32. Sari FN, Said MS, Rashid NA. The effect of ginger essential oil, lemongrass essential oil and combination of ginger and lemongrass essential oils on symptoms of menopausal women. Afr J Reprod Health. 2025. PMID 41051148. DOI 10.29063/ajrh2025/v29i9.12. (abstract)
  33. Satthanakul P, Taweechaisupapong S, Paphangkorakit J, et al.. Antimicrobial effect of lemongrass oil against oral malodour micro-organisms and the pilot study of safety and efficacy of lemongrass mouthrinse on oral malodour. J Appl Microbiol. 2015. PMID 25327222. DOI 10.1111/jam.12667. (abstract)
  34. Sharma S, Habib S, Sahu D, et al.. Chemical Properties and Therapeutic Potential of Citral, a Monoterpene Isolated from Lemongrass. Med Chem. 2021. PMID 31880247. DOI 10.2174/1573406416666191227111106. (abstract)
  35. Silva MR, Ximenes RM, da Costa JG, et al.. Comparative anticonvulsant activities of the essential oils (EOs) from Cymbopogon winterianus Jowitt and Cymbopogon citratus (DC) Stapf. in mice. Naunyn Schmiedebergs Arch Pharmacol. 2010. PMID 20237771. DOI 10.1007/s00210-010-0494-9. (abstract)
  36. Subha DS, Pradeep T. Periodontal Therapy with 0.25% Lemongrass Oil Mouthwash in Reducing Risk of Cardiovascular Diseases: A 3-Arm Prospective Parallel Experimental Study. Ethiop J Health Sci. 2017. PMID 29217959. DOI 10.4314/ejhs.v27i5.12. (abstract)
  37. Tisserand Institute. Safety guidelines (Tisserand Institute). tisserandinstitute.org, read 2026-10-25. 2026. (full-text)
  38. Uter W, Schmidt E, Geier J, et al.. Contact allergy to essential oils: current patch test results (2000-2008) from the Information Network of Departments of Dermatology (IVDK). Contact Dermatitis. 2010. PMID 20946456. DOI 10.1111/j.1600-0536.2010.01768.x. (abstract)
  39. Wasey F, Tantray S, Ahluwalia R, et al.. Comparative Evaluation of 0.25% Lemongrass Oil Mouthwash and 0.2% Chlorhexidine Mouthwash in Fixed Orthodontic Patients Suffering from Gingivitis. J Contemp Dent Pract. 2023. PMID 37534506. DOI 10.5005/jp-journals-10024-3516. (abstract)
  40. de Groot A, Schmidt E. Essential Oils, Part V: Peppermint Oil, Lavender Oil, and Lemongrass Oil. Dermatitis. 2016. PMID 27775966. DOI 10.1097/DER.0000000000000218. (abstract)

Where to buy

Check the label first. Whatever you buy, look for these:

  • The botanical (Latin) name on the label and 100% pure oil
  • A dark glass bottle and a batch number
  • Essential oils are strong: dilute for skin, and do not swallow unless a qualified professional directs it
  • Keep away from children and pets

Talk to a pharmacist or doctor before you start any supplement, especially if you take medicines. See the Safety tab for interactions.

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Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.