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Smoothies: Nutrients, What Research Shows and Safety

Smoothies as a drink: USDA values for two store-style smoothies, sugar and calories, blended-vs-whole-fruit studies, and food safety with juice, frozen berries and pregnancy.

Content last updated . This page has not been medically reviewed.

Close-up of smoothies: nutrients, what research shows and safety

A smoothie is a drink made by blending whole fruit, and sometimes vegetables, yogurt, milk, ice or juice, into one thick drink. Unlike juice, blending can keep some fiber in the glass [6], but the NHS notes that crushing fruit releases its sugars [3], and a drink is easy to finish quickly. There is no standard smoothie, so this page uses two USDA entries as examples and says plainly what the research does and does not show. It keeps smoothies apart from juice cleanses, powders and supplements.

Read this first

  • Smoothies vary hugely. USDA lists two very different ones: a bottled fruit juice smoothie (mango) and a fast-food strawberry-banana smoothie made with ice and low-fat yogurt. [1] [2] Each has about 12.5 g of sugars per 100 g, which is about 30 g in 8 fluid ounces and 44 g in 12. [1] [2]
  • The NHS counts smoothies with juice, not as extra fruit. It lets unsweetened juice and smoothies together count as at most one portion of 5 A DAY, up to 150 ml a day, because crushing fruit releases sugars that can damage teeth. [3]
  • Food safety: the FDA says outbreaks have been linked to smoothies made with unpasteurized juice. [8] A 2023 US hepatitis A outbreak was linked to frozen strawberries. [10] Pregnant women should avoid unpasteurized juice. [8]
  • Blending is not clearly worse for blood sugar than eating the fruit whole in the small studies we read, but those were in healthy people. [5] [6]
  • Medicines: if you add leafy greens and take warfarin, keep vitamin K steady. [13]
  • Emergency: smoothies can contain milk, yogurt, nut butters, seeds or protein powders. For trouble breathing or swelling of the face or throat after any food, call 911 (or your local emergency number).

What is in it (USDA values)

USDA lists two smoothie items (SR Legacy). Both are per 100 g, with the USDA household portion shown. They are different products, so do not read them as one "average" smoothie. [1] [2] A dash means USDA lists no value.

NutrientBottled mango fruit juice smoothie, per 100 g [1]Same, per 8 fl oz (240 g) [1]Strawberry-banana smoothie with low-fat yogurt, per 100 g [2]Same, per 12 fl oz (347 g) and % Daily Value [2]
Energy63 kcal151 kcal65 kcal226 kcal (not set)
Total sugars12.5 g30.0 g12.68 g44.0 g (no DV)
Carbohydrate15.0 g36.0 g15.05 g52.2 g (19%)
Fiber0 g0 g0.9 g3.1 g (11%)
Protein0.42 g1.0 g0.86 g3.0 g (6%)
Total fat0 g0 g0.14 g0.5 g (1%)
Vitamin C2.5 mg6.0 mg5.2 mg18.0 mg (20%)
Manganese--0.212 mg0.74 mg (32%)
Vitamin B6--0.108 mg0.37 mg (22%)
Copper--0.038 mg0.13 mg (15%)
Potassium142 mg341 mg (7%)131 mg455 mg (10%)
Calcium8 mg19 mg (1%)20 mg69 mg (5%)
Sodium4 mg10 mg14 mg49 mg (2%)

% Daily Value uses the FDA 2016 Daily Values; values vary with recipe, fruit, size and brand. The serving figures are the 100 g values multiplied by 2.4 and 3.47. USDA lists no caffeine and no alcohol for either item. [1] [2] The fiber difference shows why the recipe matters: the bottled juice smoothie lists 0 g of fiber, while the yogurt smoothie lists 0.9 g per 100 g. [1] [2] USDA does not say how much of the sugar was added, so we cannot tell added from natural sugars. We did not read a source that measured plant compounds in these products, so we make no antioxidant claim.

What research says

Health goalWhat the sources foundStrength of evidenceWhat was studied
Blood sugar after drinkingTwo commercial fruit smoothies had a low glycemic index (39 and 36) in 10 people, and some fruit fiber was still present after processing. [6] In 20 healthy young adults, blended apple and blackberries gave a lower peak and lower overall glucose rise than the same whole fruit; the authors guessed it might be related to fiber and nutrients released from ground blackberry seeds. [5]Mixed (small studies in healthy people; not people with diabetes)Commercial smoothies; blended versus whole fruit [5] [6]
Feeling fullIn a test with 47 adults, how full people felt depended on how food-like the drink seemed and how fast it was drunk. Later energy intake did not differ between a smoothie, the same fruit eaten whole and other energy drinks. [7]MixedA fruit smoothie versus its whole-fruit equivalent and other drinks, short-term [7]
Mental health, fatigue and fitnessIn 311 people receiving opioid treatment, a daily 250 ml fruit smoothie for 16 weeks did not change distress, fatigue, fitness, carotenoid or folate levels. The authors cite poor adherence. [12]No good evidence of benefit (for those outcomes in that group)Daily fruit smoothie versus none [12]
Eating more fruit and vegetablesThe NHS counts at most one portion a day for juice and smoothies together. [3]Official guidanceNot a trial
Weight, diabetes, heart diseaseWe did not read a trial of smoothies for these.No good evidence of benefit found in the sources we readNot applicable
"Detox" or cleansingNot supported by the sources we read; see the juice cleanse guide.No good evidence of benefitNot applicable

We did not check who funded the glucose and fullness studies, so we say nothing about it.

Eaten as food vs taken as juice or supplement. The studies above used whole-fruit drinks. Smoothies made with protein powders, supplements or juice concentrates are different products, and we did not read trials on them. A smoothie made mostly from juice (like the bottled mango example) is closer to juice than to blended whole fruit. [1] See Fruit juice vs whole fruit.

How much is a normal serving

USDA's household portions are 8 fluid ounces (240 g) for the bottled mango smoothie and 12 fluid ounces (347 g) for the strawberry-banana one. [1] [2] That is information, not a prescription. The NHS counts unsweetened juice and smoothies together as at most one portion of 5 A DAY and advises 150 ml a day. [3] WHO recommends keeping free sugars, which include sugars in fruit juices, under 10% of daily energy. [4] The 2020-2025 Dietary Guidelines for Americans say fruit choices should be "especially whole fruit." [15] For children, the American Academy of Pediatrics (2017) advises no juice in the first year and at most 4 oz a day at ages 1 to 3, and prefers whole fruit; it does not give a separate figure for smoothies in the page we read. [11]

Safety, allergy and medicines

  • Sugar and calories: the two USDA smoothies list 30 g and 44 g of sugars per serving. [1] [2] The NHS says even unsweetened smoothies are sugary and suggests having them with meals rather than between meals to protect teeth. [3]
  • Unpasteurized juice: the FDA says outbreaks have been tied to smoothies made with unpasteurized juice, and that pasteurized juice is safe. Confirm the juice is pasteurized and wash fresh fruit. [8] The FDA says untreated juice must carry a warning label, and that children, older adults, pregnant women and people with weakened immune systems can become seriously ill from it. [9]
  • Frozen berries: the FDA and CDC investigated hepatitis A illnesses (10 cases, 4 hospitalizations) linked to recalled frozen strawberries in 2023; the advice was not to eat recalled product, and to talk to a clinician about post-exposure vaccination within 14 days if you ate it. [10] The page we read did not say whether freezing kills the virus.
  • Washing produce: the FDA says rinse produce under running water without soap, scrub with a brush, and cut away damaged areas; avoid raw sprouts of any kind in pregnancy. [8]
  • Pregnancy and breastfeeding: pregnant women should avoid unpasteurized juice. [8] We did not read a source on other smoothie ingredients in pregnancy.
  • Warfarin: kale, spinach and other leafy greens are rich in vitamin K, and sudden changes can change the effect of warfarin. [13] Keep greens steady and tell your prescriber. See Foods and medicine interactions.
  • Kidney disease and potassium: USDA lists 455 mg of potassium in the 12 fl oz strawberry-banana smoothie. [2] The National Kidney Foundation says people with kidney disease may be advised to limit high-potassium foods; bananas and other ingredients vary. [14]
  • Diabetes: the sugar content is high, and we did not find a trial in people with diabetes. Ask a clinician or dietitian.
  • Allergy: smoothies often include milk, yogurt, nuts, seeds or protein powders. Read the ingredient list; for trouble breathing or swelling of the face or throat, call 911. See Food allergy basics and emergency signs.
  • Children: the AAP says unpasteurized juice should be strongly discouraged for children of all ages. [11]

Choosing, storing and food safety

  • Ask whether any juice in a smoothie bar's recipe is pasteurized. [8]
  • At home, wash fruit and your hands (at least 20 seconds), and keep ingredients cold. [9]
  • We did not read a source on how long a blended smoothie keeps; drink it soon after making it.

Related pages

BeverageBlended fruit and vegetable drinks

Health connections for Smoothies

What research links to eating or drinking this food, and how strong the evidence is. Many studies are observational or use juice, powder, oil or extracts rather than the food as eaten; each card says which.

Smoothies and blood sugar after drinking

Preliminary or mixed

Two commercial fruit smoothies had a low glycemic index (39 and 36) in 10 people, and in 20 healthy young adults blended apple and blackberries gave a lower peak and lower overall glucose rise than the same whole fruit.

Supplements: Small studies in healthy people, not people with diabetes; who funded them was not checked.

Smoothies and feeling full

Preliminary or mixed

In a test with 47 adults, fullness depended on how food-like the drink seemed and how fast it was drunk, and later energy intake did not differ between a smoothie, the same fruit eaten whole and other energy drinks.

Supplements: Short-term test only.

Vitamins in a yogurt-based fruit smoothie

Established role

One 12 fl oz USDA strawberry-banana smoothie gives about 32% of the Daily Value for manganese, 22% for vitamin B6, 20% for vitamin C, 15% for copper and 11% for fiber.

Supplements: Applies to that recipe only; the bottled mango example gives much less.

Smoothies and mood, fatigue or fitness

Not enough evidence

In 311 people receiving opioid treatment, a daily 250 ml fruit smoothie for 16 weeks did not change psychological distress, fatigue, physical fitness, carotenoids or folate; the authors cite poor adherence.

Supplements: No benefit shown for those outcomes in that group.

Connected topics

Open a group to see how each topic connects and how strong the evidence is.

Root causes (1)
  • Greens added to a smoothie add vitamin K, which can change the effect of warfarin; keep intake steady and tell the prescriber.

Conditions & symptoms (3)
  • Dental CariesDocumented risk

    The NHS says crushing fruit releases sugars that can damage teeth; it does not name cavities specifically.

  • Food PoisoningDocumented risk

    Outbreaks have been linked to smoothies made with unpasteurized juice; confirm the juice is pasteurized and wash produce.

  • Hepatitis ADocumented risk

    A 2023 US outbreak (10 cases, 4 hospitalizations) was linked to recalled frozen strawberries; follow recall advice.

Documented risks and interactions (5)
  • Sugar and calories in smoothies. USDA lists about 12.5 g of sugars per 100 g for a bottled mango smoothie (30 g in 8 fl oz) and a fast-food strawberry-banana smoothie (44 g in 12 fl oz). WHO counts sugars in fruit juices as free sugars to be kept under 10% of daily energy.
  • Blended fruit sugars and teeth. The NHS says crushing fruit releases its sugars, which can damage teeth, that even unsweetened juice and smoothies are sugary, and suggests drinking them with meals rather than between meals.
  • Smoothies made with unpasteurized juice. The FDA says outbreaks have been linked to smoothies made with unpasteurized juice, that pasteurized juice is safe, and that pregnant women should avoid unpasteurized juice.
  • Frozen berries and hepatitis A. The FDA and CDC investigated 10 hepatitis A cases (4 hospitalizations) linked to recalled frozen strawberries in 2023; advice was not to eat recalled product and to talk to a clinician about post-exposure vaccination within 14 days. The page we read does not say whether freezing kills the virus.
  • Leafy greens in smoothies and warfarin. Leafy greens such as kale and spinach are rich in vitamin K, and MedlinePlus says sudden changes in vitamin K intake can change the effect of warfarin.

Explore all 26 beverages

Frequently asked questions

Is a smoothie as good as eating the fruit?

In the small studies we read, blended fruit did not raise blood sugar more than whole fruit in healthy adults. [5] [6] Fullness and later eating were similar to eating the fruit whole. [7] The NHS still limits juice and smoothies to 150 ml a day as one portion. [3]

Do smoothies have a lot of sugar?

The two USDA examples have about 12.5 g of sugars per 100 g, which is 30 to 44 g in a typical bottle or cup. [1] [2] Homemade smoothies depend on the recipe.

Are smoothies safe in pregnancy?

The FDA says pregnant women should avoid unpasteurized juice, and outbreaks have been linked to smoothies made with it. [8] Wash all produce and avoid raw sprouts. [8]

Can I put greens in a smoothie if I take warfarin?

Leafy greens are rich in vitamin K, and sudden changes can change warfarin's effect. [13] Keep the amount steady and tell your prescriber.

Do smoothies help with mood or energy?

One trial of 311 people receiving opioid treatment found a daily fruit smoothie for 16 weeks did not change distress, fatigue or fitness. [12] We did not find other trials for these goals.

References
  1. U.S. Department of Agriculture. FoodData Central: Fruit juice smoothie, mango (SR Legacy, FDC 167795). April 2018 release. Read 2026-10-24.
  2. U.S. Department of Agriculture. FoodData Central: Fast foods, strawberry banana smoothie made with ice and low-fat yogurt (SR Legacy, FDC 170775). April 2018 release. Read 2026-10-24.
  3. NHS. 5 A DAY: what counts. Read 2026-10-24.
  4. WHO. WHO calls on countries to reduce sugars intake among adults and children. 4 March 2015. Read 2026-10-24.
  5. Crummett LT, Grosso RJ. Postprandial glycemic response to whole fruit versus blended fruit in healthy, young adults. Nutrients 2022 (abstract read via Europe PMC). Read 2026-10-24.
  6. Saltaouras G et al. Glycaemic index, glycaemic load and dietary fibre characteristics of two commercially available fruit smoothies. Int J Food Sci Nutr 2019 (abstract read via Europe PMC). Read 2026-10-24.
  7. Rogers PJ, Shahrokni R. A comparison of the satiety effects of a fruit smoothie, its fresh fruit equivalent and other drinks. Nutrients 2018 (abstract read via Europe PMC). Read 2026-10-24.
  8. U.S. Food and Drug Administration. Fruits, veggies and juices (food safety for moms-to-be). Read 2026-10-24.
  9. U.S. Food and Drug Administration. What you need to know about juice safety. Read 2026-10-24.
  10. U.S. Food and Drug Administration. Outbreak investigation of hepatitis A virus infections: frozen strawberries (February 2023). Outbreak declared over September 2023. Read 2026-10-24.
  11. American Academy of Pediatrics (HealthyChildren.org). AAP recommends no fruit juice for children under 1 year. Published 22 May 2017. Read 2026-10-24.
  12. Javadi Arjmand E et al. The effect of fruit smoothie supplementation on psychological distress and biomarkers among people with opioid dependence receiving opioid agonist therapy: a randomized controlled trial. BMC Med 2025 (abstract read via Europe PMC). Read 2026-10-24.
  13. MedlinePlus. Vitamin K. Review date 2025-01-21. Read 2026-10-24.
  14. National Kidney Foundation. Potassium and your CKD diet. Read 2026-10-24.
  15. U.S. Department of Agriculture and U.S. Department of Health and Human Services. Dietary Guidelines for Americans, 2020-2025: Executive Summary. December 2020. Read 2026-10-24.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.