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Butter.

Oils & Fats · Dairy fat

Butter

Dairy fat (cows' milk) · also called Cows' milk butter, mantequilla (Spanish)

Butter is the fat of cows' milk, made by churning cream. A tablespoon has about 102 calories and 7.3 g of saturated fat. In trials it raises LDL cholesterol more than most liquid plant oils. Large studies of eating habits found no clear link between butter and heart disease, but that is an association, not proof. The main cautions are milk allergy and, in pregnancy, unpasteurised butter.

General information, not medical advice. Last substantive update · Not medically reviewed. A named clinician has not signed off on this page. How this page is made

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About Butter

Butter is a flavourful, calorie-dense dairy fat. Trials show it raises LDL cholesterol more than most liquid plant oils, while eating-habit studies find no clear link with heart disease. Official advice still ranks unsaturated oils above it, so it is best seen as a food to enjoy in moderation rather than a health food.

What it is

Butter is the fat of cows' milk. It is made by churning cream until the fat separates from the liquid, and it is sold salted or unsalted.

One tablespoon (14.2 g) of salted butter has about 102 calories, 11.5 g of fat and 7.3 g of saturated fat (USDA). It has almost no protein, carbohydrate or fibre. It supplies some vitamin A (about 97 micrograms) and vitamin E, and about 91 mg of sodium when salted.

13

What the research shows

The firmest result is about LDL cholesterol. In a pooled analysis of 54 trials, many plant oils and beef fat lowered LDL more than butter. A Nordic review agreed.

Reviews of trials of cutting saturated fat found fewer combined heart events after two years or more. Those trials were about saturated fat overall, so they do not test butter alone.

Large studies of eating habits found no clear link between butter and heart disease or stroke, a very small link with higher all-cause death and a small link with lower diabetes. These show links, not cause. The authors said the data do not support a big push to eat more or less butter.

6 4 1 5 3 2

Butter versus ghee, spreads and supplements

These findings are about butter eaten as food. Ghee, margarine and spreads, and fish oil are different products with their own pages, and the studies here do not test them.

We read no trial of butter taken as a supplement.

1 3

At a glance

Traditional uses history, not proof

  • Everyday cooking and baking fat
  • No source we read documents traditional health uses

Studied for research

  • Blood LDL cholesterol compared with other fats, moderate certainty (butter raises it more)
  • Heart disease and stroke in eating-habit studies, low certainty (no clear link)
  • Cutting saturated fat in general and heart events, moderate certainty
  • Type 2 diabetes risk, very low certainty
  • Swapping butter for olive oil, low certainty

Main compounds

  • Saturated fat (about 7.3 g per tablespoon)
  • Natural trans fat (about 0.5 g per tablespoon)
  • Vitamin A as retinol (about 97 micrograms per tablespoon)
  • Cholesterol (about 31 mg per tablespoon)

Common forms

  • Salted butter (the form the nutrition figures describe)
  • Unsalted butter
  • Cultured or European-style butter
  • Ghee and margarine are different products, covered on their own pages

Research links: NHS: Eat less saturated fat · NHS: Foods to avoid in pregnancy · Butter and cardiovascular disease, diabetes and death, meta-analysis (PLoS One, 2016) · Oils and solid fats and blood lipids, network meta-analysis (Journal of Lipid Research, 2018) · Research Library · Genes & Biomarkers Library

What it is and its history

Accepted scientific name
Butter
Naming authority
A dairy food, not a plant or species
Common names
Butter (English); Cow's milk butter (English); Mantequilla (Spanish)
Family or group
Dairy fats (the existing summary groups it as an animal fat).
Harvest and processing
Made by churning cream so the fat separates from the liquid; sold salted or unsalted (existing summary; no source read for the method). Cultured or European-style butter is made from fermented cream (existing summary).
Look-alikes and adulterants
Name: Ghee (clarified butter); Note: A different product with the water and milk solids removed; evidence on butter does not automatically apply to it.; Name: Margarine and spreads; Note: Made from vegetable oils, not milk fat; a separate page covers them.

Photographs

Butter close-up
Butter.

Traditional use and history history, not clinical proof

Tradition or eraDocumented useSource
Everyday cooking fatButter is a long-standing household food; no source read documents when or where it began.NOT verified (no source read)

Traditional use shows how it was used. It does not show that it works or is safe today.

What is inside, and how it may work

What it contains and how those compounds act in cells and animals. Laboratory and animal mechanisms are not proven effects in people.

Main compounds

CompoundFamilyWhere it is concentratedActivity studiedLevel of evidence
Saturated fatfatWhole butter
51.4 g per 100 g; 7.3 g in 1 tablespoon (USDA)
Raises LDL cholesterol in trials compared with unsaturated oils. 13 6Human trials and composition data
Natural trans fatfatWhole butter
About 3.3 g per 100 g (USDA)
Occurs naturally in milk fat from ruminant animals; the FDA says its actions on industrial trans fat do not cover it. 13 7Composition data and regulator statement
Vitamin A (retinol)fat-soluble vitaminWhole butter
684 micrograms RAE per 100 g; 97 micrograms in 1 tablespoon (USDA)
Provides preformed vitamin A in the diet; not tested here as a treatment. 13 12Composition data

Mechanisms, receptors and pathways

Target or pathwayGene or receptorWhat was foundLevel
Saturated fat and LDL cholesterolReplacing saturated fat with unsaturated fat lowers LDL cholesterol, which the AHA calls a cause of atherosclerosis; the specific pathways were not read. 5 6Human trials and expert advisory

Absorption, metabolism and elimination

Absorption
Not researched.
Distribution
Not found.
Metabolism
Not found.
Elimination
Not found.
Bioavailability
Not established.

Isolated compounds versus whole extracts

Everything here is about butter as a food. Ghee, margarine and spreads, fish oil and supplements are different products and are not covered by these studies. Studies of saturated fat overall do not test butter alone.

Nutritional composition

Per 100 g of salted butter (USDA FoodData Central, SR Legacy item 173410, taken from a saved copy of the data): 717 kcal, 81.1 g fat (51.4 g saturated, 21.0 g monounsaturated, 3.0 g polyunsaturated, 3.3 g trans), 215 mg cholesterol, 643 mg sodium, 684 micrograms vitamin A (RAE), 2.32 mg vitamin E, 0.85 g protein, 0.06 g carbohydrate. One tablespoon (14.2 g) has about 102 kcal and 7.3 g saturated fat. Butter has almost no protein, carbohydrate or fibre. Unsalted butter has the same calories and fat but far less sodium. Values vary with the cow's feed and the brand.

8benefits and uses looked at
13studies and sources checked
Moderate certaintybest evidence rating found
4lab markers tracked in trials

2 moderate certainty2 low certainty2 very low certainty2 not enough evidence

What was looked at

The 8 benefits and uses checked for Butter, each with how strong the evidence is. Tap one to open it.

Lab markers tracked in the studies

LDL cholesterolCombined cardiovascular events (saturated fat in general)All-cause mortalityNew cases of type 2 diabetes

What is Butter good for?

The main studied questions and how strong the human evidence is for each. Most results are links seen in eating habits or changes in a blood marker. Butter is a food, and none of this shows that it treats or prevents a disease.

Blood LDL cholesterol compared with other fats and oilsModerate certaintyIn 54 trials, safflower, sunflower, rapeseed, flaxseed, corn, olive, soybean, palm and coconut oil and beef fat all lowered LDL by 0.23 to 0.42 mmol/L more than butter. Butter is the higher-LDL choice, so this is a caution, not a benefit. Heart disease and stroke in people who eat more butterLow certaintyA review of 15 cohorts (636,151 people) found no clear link between butter and cardiovascular disease, coronary heart disease or stroke. No trial of butter and heart attacks was found. Cutting saturated fat (the main fat in butter) and heart eventsModerate certaintyAcross about 59,000 people, cutting saturated fat for at least two years lowered combined cardiovascular events by 21%, with little or no effect on deaths. This is saturated fat overall, not butter alone. Swapping butter for olive oilLow certaintyIn 3 cohorts, using olive oil instead of butter went with a slightly lower risk of cardiovascular disease (hazard ratio 0.96). It is a small link seen in eating habits. Type 2 diabetes riskVery low certaintyMore butter went with slightly lower diabetes risk in 11 cohorts (RR 0.96 per tablespoon a day). The effect is tiny and does not show butter prevents diabetes. Death from any causeVery low certaintyThe same cohorts showed a borderline, very slightly higher risk of death from any cause (RR 1.01). It could be chance or other habits. CancerNot enough evidenceThe evidence is sparse and mostly from case-control studies. One review says butter may be linked with some cancer types. This is unsettled. 'Natural fat' and brain or heart protection claimsNot enough evidenceNo source we read shows butter protects the heart or brain. Claims about grass-fed butter were not checked.

Benefits, one by one

Each card is a research question, not a promise. Tap a goal to filter. Open a card to see the studies, doses and limits.

Blood LDL cholesterol compared with other fats and oils

Moderate certainty

In controlled trials, butter raised LDL ('bad') cholesterol more than most liquid plant oils and beef fat. This is a harm signal, not a benefit, and it is the best-supported finding about butter.

2 studiesButter eaten as a food, compared with other fats and oils in the diet.

Studies, doses and limits

What the trials found

A 2018 network meta-analysis of 54 trials found that safflower, sunflower, rapeseed, flaxseed, corn, olive, soybean, palm and coconut oil, and beef fat all lowered LDL by 0.23 to 0.42 mmol/L more than butter. A Nordic review agreed that butter raises LDL compared with virtually all other fats and oils.

Results

Higher LDL with butter than with most other fats and oils tested.

Effect sizes as reported

LDL 0.23 to 0.42 mmol/L lower with the listed oils and beef fat than with butter (Schwingshackl 2018).

Why this rating

Randomised trials, and the Nordic review and the AHA advisory point the same way. The abstract gives no GRADE rating, the outcome is a blood marker, and the Nordic authors call the reviews they found low in methodological quality.

Form and dose studied

Butter eaten as a food, compared with other fats and oils in the diet.

Who was studied

Adults in trials of 3 weeks or longer.

Limits

Measures LDL, not heart attacks. Trials differ in how the fats were given.

Why researchers looked

Butter is about half saturated fat, and saturated fat is known to raise LDL cholesterol.

Proposed mechanism Authoritative guidance

Saturated fat raises LDL in the blood; the exact pathways were not read in the sources used.

A proposed mechanism does not show that the effect happens in people.

People with high cholesterol or heart disease should ask their clinician about their own fat intake.

6 4

Heart disease and stroke in people who eat more butter

Low certainty

Large studies that followed people over time found no clear link between how much butter they ate and heart disease or stroke. This does not show butter protects the heart.

1 studiesButter as eaten in usual diets.

Studies, doses and limits

What the trials found

A 2016 review of 9 publications (15 cohorts, 636,151 people) found butter was not significantly linked with cardiovascular disease, coronary heart disease or stroke. No randomised trial of butter and heart attacks was found.

Results

No clear link in either direction.

Effect sizes as reported

Per 14 g (1 tablespoon) a day: cardiovascular disease RR 1.00 (0.98-1.02); coronary heart disease RR 0.99 (0.96-1.03); stroke RR 1.01 (0.98-1.03).

Why this rating

Observational data only. People who eat more butter may differ in other ways. The search ended in 2015. The authors say the findings do not support a major emphasis on eating more or less butter.

Form and dose studied

Butter as eaten in usual diets.

Who was studied

Adults in cohort studies in several countries.

Limits

Association, not cause; no butter trial on heart events.

Why researchers looked

Dairy fat has been suggested to behave differently from other saturated fat, so researchers pooled the eating-habit studies on butter.

Proposed mechanism Unknown

Not established.

A proposed mechanism does not show that the effect happens in people.

See the safety tab.

3

Cutting saturated fat (the main fat in butter) and heart events

Moderate certainty

Trials of lowering saturated fat for at least two years found fewer combined heart events. This is about saturated fat overall, not butter on its own.

2 studiesDiets that reduced saturated fat from any source.

Studies, doses and limits

What the trials found

A Cochrane review of 15 randomised trials (about 59,000 people) found that reducing saturated fat for at least two years cut combined cardiovascular events by 21%, with little or no effect on deaths. The American Heart Association advises replacing saturated fat with unsaturated fat, especially polyunsaturated fat.

Results

Fewer combined cardiovascular events; little or no effect on all-cause or cardiovascular death.

Effect sizes as reported

Combined cardiovascular events RR 0.79 (95% CI 0.66-0.93, 11 trials); all-cause death RR 0.96 (0.90-1.03).

Why this rating

The Cochrane authors rated the combined-events result moderate (GRADE). It is about saturated fat overall, and butter was not tested alone. A later update of the review exists.

Form and dose studied

Diets that reduced saturated fat from any source.

Who was studied

Adults in trials lasting 24 months or more.

Limits

Not specific to butter. High variation between trials (I2 65%). WHO-funded.

Why researchers looked

Butter is a large source of saturated fat in many diets, so advice on saturated fat is relevant to it.

Proposed mechanism Human trial

Lower saturated fat lowers LDL cholesterol, and the Cochrane authors found larger cuts in saturated fat went with larger drops in heart events.

A proposed mechanism does not show that the effect happens in people.

None specific.

1 5

Type 2 diabetes risk in people who eat more butter

Very low certainty

People who ate more butter had a slightly lower chance of type 2 diabetes in cohort studies. This is a link, not proof, and it is a small difference.

2 studiesButter as eaten in usual diets.

Studies, doses and limits

What the trials found

The 2016 review of 11 cohorts found a small inverse link with diabetes. The Nordic scoping review also reports a possible slightly lower risk in prospective cohorts.

Results

Slightly lower diabetes risk with more butter.

Effect sizes as reported

Per 14 g a day: type 2 diabetes RR 0.96 (95% CI 0.93-0.99, 11 cohorts).

Why this rating

Observational only, a very small effect, and a lower bound close to no effect. The Nordic authors rate the reviews low in methodological quality.

Form and dose studied

Butter as eaten in usual diets.

Who was studied

Adults in cohort studies.

Limits

Association, not cause. It does not show that eating butter prevents diabetes.

Why researchers looked

Dairy foods have been linked with lower diabetes risk, so butter was pooled on its own.

Proposed mechanism Unknown

Not established.

A proposed mechanism does not show that the effect happens in people.

People with diabetes should ask their care team about fats in their own plan.

3 4

Death from any cause

Very low certainty

In the same studies, more butter went with a very slightly higher chance of death from any cause. The size is tiny and the finding is borderline.

2 studiesButter as eaten in usual diets.

Studies, doses and limits

What the trials found

The 2016 review of 9 cohorts found a weak link with higher all-cause death. The Nordic review says the same pattern may exist.

Results

Very slightly higher risk with more butter.

Effect sizes as reported

Per 14 g a day: all-cause death RR 1.01 (95% CI 1.00-1.03, 9 cohorts).

Why this rating

Observational, with a confidence interval touching 1.00, so it could be chance or other habits of people who eat more butter.

Form and dose studied

Butter as eaten in usual diets.

Who was studied

Adults in cohort studies.

Limits

Association only; tiny effect.

Why researchers looked

Researchers pooled butter intake against total deaths to see whether it helps or harms overall.

Proposed mechanism Unknown

Not established.

A proposed mechanism does not show that the effect happens in people.

None specific.

3 4

Swapping butter for olive oil

Low certainty

In long-term studies, people whose diets used olive oil instead of butter had a slightly lower risk of cardiovascular disease.

1 studiesOlive oil replacing butter in the diet.

Studies, doses and limits

What the trials found

A 2023 review of prospective cohorts rated as moderate certainty (GRADE) a lower cardiovascular disease risk when olive oil replaced butter, from 3 cohorts.

Results

Slightly lower risk with olive oil instead of butter.

Effect sizes as reported

Cardiovascular disease SHR 0.96 (95% CI 0.95-0.98, 3 cohorts).

Why this rating

The authors' own GRADE for this result was moderate, but it comes from only 3 observational cohorts and the effect is small, so we show it as low.

Form and dose studied

Olive oil replacing butter in the diet.

Who was studied

Adults in cohort studies.

Limits

Association, not cause; people who choose olive oil may differ in other ways.

Why researchers looked

Public advice is to replace saturated fat with unsaturated fat, and olive oil is a common choice.

Proposed mechanism Preliminary mechanism

Likely linked to the LDL difference between the fats, but not tested in these studies.

A proposed mechanism does not show that the effect happens in people.

None specific.

2

Cancer

Not enough evidence

The evidence on butter and cancer is thin. One review says butter may be linked with some cancer types. This is not settled.

1 studiesButter as eaten.

Studies, doses and limits

What the trials found

The Nordic scoping review says the cancer evidence is sparse and mainly from case-control studies, and that butter may be associated with increased risk of certain cancer types.

Results

Possible higher risk for some cancers; no figures in the abstract.

Why this rating

Sparse, case-control evidence in low-quality reviews, as the authors state.

Form and dose studied

Butter as eaten.

Who was studied

Adults.

Limits

No effect sizes read.

Why researchers looked

Researchers looked for links between dietary fats and cancer.

Proposed mechanism Unknown

Not established.

A proposed mechanism does not show that the effect happens in people.

None specific.

4

Claims that butter is a health food (grass-fed, 'natural fat', brain health)

Not enough evidence

No source read shows butter protects the heart or brain or treats any condition. Claims about grass-fed butter were not checked.

1 studiesButter as eaten.

Studies, doses and limits

What the trials found

The 2016 review concluded that butter data do not support major emphasis on eating more or less of it. No trial was found showing a health benefit of butter.

Results

No benefit shown.

Why this rating

No trials of butter for these claims were found in the sources read.

Form and dose studied

Butter as eaten.

Limits

Grass-fed versus conventional butter was not looked up.

Why researchers looked

Popular books and social media often promote butter as a healthy fat.

Traditional use

Butter has been a household food for a very long time; no source read documents health uses.

Proposed mechanism Unknown

Not established.

A proposed mechanism does not show that the effect happens in people.

None specific.

3

Connections to the rest of health

How Butter connects to the rest of our health knowledge graph. Every link says what kind of connection it is. A safety link (for example to the liver) is a warning, not a benefit. A study that merely mentions a topic never creates a benefit link.

Explore every connection: goals, body systems, organs, symptoms, genes

A. Wellness goals

Connected toKind of connectionEvidence statusContextStudies
Heart Health Moderate certainty Blood LDL cholesterol compared with other fats and oils: In controlled trials, butter raised LDL ('bad') cholesterol more than most liquid plant oils and beef fat. This is a harm signal, not a benefit, and it is the best-supported finding about butter. 6 4
Heart Health Low certainty Heart disease and stroke in people who eat more butter: Large studies that followed people over time found no clear link between how much butter they ate and heart disease or stroke. This does not show butter protects the heart. Swapping butter for olive oil: In long-term studies, people whose diets used olive oil instead of butter had a slightly lower risk of cardiovascular disease. 3 2
Heart Health Moderate certainty Cutting saturated fat (the main fat in butter) and heart events: Trials of lowering saturated fat for at least two years found fewer combined heart events. This is about saturated fat overall, not butter on its own. 1 5
Blood Sugar Balance Very low certainty Type 2 diabetes risk in people who eat more butter: People who ate more butter had a slightly lower chance of type 2 diabetes in cohort studies. This is a link, not proof, and it is a small difference. 3 4
Longevity Very low certainty Death from any cause: In the same studies, more butter went with a very slightly higher chance of death from any cause. The size is tiny and the finding is borderline. 3 4

B. Body systems

Connected toKind of connectionEvidence statusContextStudies
Cardiovascular System Biological association Moderate certainty Studied for: Blood LDL cholesterol compared with other fats and oils Studied for: Heart disease and stroke in people who eat more butter 6 4 3 1 5 2
Endocrine System Biological association Very low certainty Studied for: Type 2 diabetes risk in people who eat more butter 3 4

E. Health conditions

Connected toKind of connectionEvidence statusContextStudies
High cholesterol Adverse effect or risk Documented risk Butter raised LDL more than most liquid plant oils in trials. Butter raised LDL cholesterol more than most liquid plant oils in trials.
Preparation or compound: Butter eaten as food
6
Milk allergy Adverse effect or risk Documented risk Butter is made from cows' milk; the NHS lists milk among common allergens. Butter is made from cows' milk.
Preparation or compound: Butter
8

I. Biomarkers

Connected toKind of connectionEvidence statusContextStudies
LDL cholesterol Biological association Moderate certainty Measured in trials: higher with butter than with most other fats and oils. A lab change is not the same as a health benefit. 6
Combined cardiovascular events (saturated fat in general) Biological association Moderate certainty Measured in trials: fewer events when saturated fat was reduced. A lab change is not the same as a health benefit. 1
All-cause mortality Biological association Very low certainty Measured in trials: very slightly higher with more butter. A lab change is not the same as a health benefit. 3
New cases of type 2 diabetes Biological association Very low certainty Measured in trials: very slightly lower with more butter. A lab change is not the same as a health benefit. 3

L. Active compounds

Connected toKind of connectionEvidence statusContextStudies
Saturated fat Biological association Human trials and composition data Raises LDL cholesterol in trials compared with unsaturated oils.
Preparation or compound: Whole butter
13 6
Natural trans fat Biological association Composition data and regulator statement Occurs naturally in milk fat from ruminant animals; the FDA says its actions on industrial trans fat do not cover it.
Preparation or compound: Whole butter
13 7
Vitamin A (retinol) Biological association Composition data Provides preformed vitamin A in the diet; not tested here as a treatment.
Preparation or compound: Whole butter
13 12

Each connection is stored with the ingredient, the connected record, the kind of connection, the evidence status, the supporting studies, the preparation or compound involved, and a review date (last reviewed October 26, 2026).

The evidence

The research centre for Butter. Every record here was checked against PubMed or the publisher's page; we never list a study we have not verified.

Evidence by outcome

Bars show how many studies we found for each outcome, not how well it works. People are added up across trials only (reviews are not added, to avoid double counting).

How we rate evidence

High certainty

Several well-run trials or reviews agree; further research is unlikely to change the picture much.

Moderate certainty

Good trials point the same way, but some doubt remains.

Low certainty

Small, short or inconsistent trials. The finding could change with better research.

Very low certainty

Very little or very weak human data. Treat as a possibility only.

Mixed findings

Trials or reviews disagree with each other.

Not enough evidence

Not enough human research to say either way.

Evidence against

Good research found no benefit, or found harm.

We take the reviewers' own risk-of-bias and GRADE statements where they exist, and otherwise judge from study size, design, consistency, directness and whether a product matches what is sold. Many publications do not make evidence high. Method note: We started from our existing butter summary, kept its USDA nutrition figures (taken from a saved copy of the USDA data), re-read PubMed abstracts for the reviews cited and re-read the NHS and FDA pages. CDC and food-allergy-charity pages could not be opened and are flagged. Only abstracts were read for studies.

Study library: every study we checked 13
StudyDesignPeopleProduct, dose, lengthResult
Hooper 2020
Reduction in saturated fat intake for cardiovascular disease.
Cochrane Database Syst Rev · PMID 32428300 · DOI
Systematic review and meta analysis of randomised trials
59000
15 randomised trials (16 comparisons), about 59,000 adults, at least 24 months, reducing saturated fat or replacing it
Lower saturated fat intake (all sources; butter is not tested alone)
At least 24 months · vs Higher saturated fat or usual diet
Cutting saturated fat for at least two years lowered combined cardiovascular events by 21% (RR 0.79), GRADE moderate. Little or no effect on all-cause or cardiovascular death. The authors say replacing saturated fat with polyunsaturated fat or carbohydrate seems useful, while replacement with monounsaturated fat is unclear.
Combined cardiovascular events RR 0.79 (95% CI 0.66-0.93, 11 trials); all-cause death RR 0.96 (0.90-1.03); cardiovascular death RR 0.95 (0.80-1.12) (0.66-0.93 (combined events))
Methods, limits and funding

Outcomes: Deaths and cardiovascular events

Limitations: About saturated fat overall, not butter. Heterogeneity was high (I2 65%). A later update of this review exists (version pub3, August 2020); numbers here are from the version read.

Funding and conflicts: Funded by a grant from the World Health Organization; the lead author is a member of a WHO nutrition guidance group

Read: abstract

Neuenschwander 2023
Substitution of animal-based with plant-based foods on cardiometabolic health and all-cause mortality: a systematic review and meta-analysis of prospective studies.
BMC Med · PMID 37968628 · DOI
Systematic review (observational cohort studies, substitution analysis)
37 publications from 24 prospective cohorts Statistical swap of butter for olive oil in the diet (3 cohorts)
Cohort follow-up · vs Butter
For cardiovascular disease, swapping butter for olive oil was linked with a lower risk (summary hazard ratio 0.96), rated moderate certainty by the authors using GRADE.
Butter replaced by olive oil: cardiovascular disease SHR 0.96 (95% CI 0.95-0.98, 3 cohorts) (0.95-0.98)
Methods, limits and funding

Outcomes: Cardiovascular disease, type 2 diabetes, all-cause death

Limitations: Observational substitution estimates from 3 cohorts; a small effect; people who choose olive oil may differ in other ways.

Funding and conflicts: Authors declared no competing interests

Read: abstract

Pimpin 2016
Is Butter Back? A Systematic Review and Meta-Analysis of Butter Consumption and Risk of Cardiovascular Disease, Diabetes, and Total Mortality.
PLoS One · PMID 27355649 · DOI
Systematic review (observational cohort studies)
636151
9 publications covering 15 country-specific cohorts of adults; 636,151 people, 6.5 million person-years, 28,271 deaths, 9,783 cases of cardiovascular disease and 23,954 cases of diabetes. No randomised trials were found.
Usual butter intake reported by participants, compared per 14 g (1 tablespoon) a day
Cohort follow-up varied · vs Lower butter intake
Butter was weakly linked with higher all-cause death (RR 1.01 per 14 g a day), not linked with cardiovascular disease, coronary heart disease or stroke, and linked with slightly lower diabetes (RR 0.96). The authors found no sign of publication bias and concluded the links are small or neutral.
Per 14 g/day: all-cause death RR 1.01 (95% CI 1.00-1.03); cardiovascular disease RR 1.00 (0.98-1.02); coronary heart disease RR 0.99 (0.96-1.03); stroke RR 1.01 (0.98-1.03); type 2 diabetes RR 0.96 (0.93-0.99) (See effect)
Methods, limits and funding

Outcomes: All-cause death, cardiovascular disease, coronary heart disease, stroke, type 2 diabetes

Limitations: Observational: shows links, not cause. Search ended in May 2015, so newer cohorts are not included. Butter is only one part of a person's diet.

Funding and conflicts: No funding statement in the abstract. The conflict statement lists consulting or honoraria for the senior author from several companies, including the Haas Avocado Board; the paper says this does not alter its data-sharing policies.

Read: abstract

Rosqvist 2024
Fats and oils - a scoping review for Nordic Nutrition Recommendations 2023.
Food Nutr Res · PMID 38370114 · DOI
Scoping review of systematic reviews
Systematic reviews and meta-analyses of fats and oils at food level n/a
Butter was not linked with cardiovascular disease in cohort studies, but may be linked with slightly lower type 2 diabetes and higher total death. The evidence on cancer is sparse and mostly case-control; butter may be linked with some cancer types. Butter raised LDL cholesterol compared with virtually all other fats and oils. The authors prefer unsaturated oils (olive, canola) over butter and tropical oils.
Narrative summary; no pooled figure
Methods, limits and funding

Outcomes: Cardiovascular disease, type 2 diabetes, total death, cancer, blood fats

Limitations: All the reviews found were of low methodological quality, so the authors urge caution.

Funding and conflicts: Authors declared none

Read: abstract

Sacks 2017
Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association.
Circulation · PMID 28620111 · DOI
Expert advisory (narrative review of trials and cohorts)
Evidence review by an American Heart Association writing group n/a
The advisory concludes strongly that lowering saturated fat and replacing it with unsaturated fats, especially polyunsaturated fats, lowers cardiovascular disease. It reports that trials replacing saturated fat with polyunsaturated vegetable oil reduced disease by about 30%, and that replacing it with refined carbohydrates and sugars did not help.
Advisory statement; not a new trial
Methods, limits and funding

Outcomes: Effect of saturated fat and its replacement on cardiovascular disease

Limitations: Expert synthesis, not a new analysis. Butter is not tested alone in the abstract.

Funding and conflicts: American Heart Association; members' disclosures are on file with the journal

Read: abstract

Schwingshackl 2018
Effects of oils and solid fats on blood lipids: a systematic review and network meta-analysis.
J Lipid Res · PMID 30006369 · DOI
Systematic review and network meta analysis of randomised trials
54 randomised trials (3 weeks or longer) comparing at least two oils or solid fats, including butter, in adults Safflower, sunflower, rapeseed, hempseed, flaxseed, corn, olive, soybean, palm and coconut oil, lard, beef fat and butter
Modelled per 10% energy exchanged (statistical unit) 3 weeks or longer · vs Other oils or fats
Safflower, sunflower, rapeseed, flaxseed, corn, olive, soybean, palm and coconut oil, and beef fat all lowered LDL cholesterol more than butter did (by 0.23 to 0.42 mmol/L). The authors say the findings support replacing high-saturated-fat foods with unsaturated oils.
LDL cholesterol lower than with butter by 0.23 to 0.42 mmol/L for the listed oils and beef fat (Not given in the abstract)
Methods, limits and funding

Outcomes: LDL cholesterol, total cholesterol, HDL cholesterol, triglycerides

Limitations: The authors note limits in the data. It measures a blood marker, not heart attacks or strokes. The abstract does not give a GRADE rating.

Funding and conflicts: Authors declared no competing interests

Read: abstract

s-fda-trans-fat
US FDA: Trans Fat
· Source
Authoritative guidance
n/a

Methods, limits and funding

Read: full-text

s-nhs-food-allergy
NHS: Food allergy
· Source
Authoritative guidance
n/a

Methods, limits and funding

Read: full-text

s-nhs-lactose
NHS: Lactose intolerance
· Source
Authoritative guidance
n/a

Methods, limits and funding

Read: full-text

s-nhs-pregnancy-foods
NHS: Foods to avoid in pregnancy
· Source
Authoritative guidance
n/a

Methods, limits and funding

Read: full-text

s-nhs-saturated-fat
NHS: Eat less saturated fat
· Source
Authoritative guidance
n/a

Methods, limits and funding

Read: full-text

s-nhs-vitamin-a
NHS: Vitamin A
· Source
Authoritative guidance
n/a

Methods, limits and funding

Read: full-text

s-usda-fdc-173410
USDA FoodData Central: Butter, salted (FDC 173410, SR Legacy, April 2018)
· Source
Reference database
n/a

Methods, limits and funding

Read: partial

What we do not know yet

  • No trial has tested butter itself against other fats for heart attacks, stroke or death.
  • The butter cohort review searched up to May 2015; newer cohorts were not read.
  • Grass-fed, cultured and unsalted butter were not compared in any source read.
  • Pregnancy beyond the unpasteurised-butter warning, breastfeeding, and infant use were not covered.
  • The lactose content of butter and contaminants were not found in the sources read.

How new research is added

New studies are found by a saved PubMed search and placed in a review queue before the page changes.

Lab markers

What changed in blood or saliva tests during trials. A changed number is not the same as feeling or being healthier, and we give no "normal ranges".

Metabolic 1

●

LDL cholesterol

Higher with butter than with most other fats and oils in trials

The so-called bad cholesterol carried in the blood.

Moderate certainty
Results and what it means

Why it was measured

A common heart-risk marker.

Statistical vs. clinical meaning

A clear difference in a blood marker; the size of the effect on heart attacks depends on the whole diet.

Safety implication

Relevant for people with high cholesterol or heart disease.

StudyResultPeopleProduct
6Safflower, sunflower, rapeseed, flaxseed, corn, olive, soybean, palm and coconut oil and beef fat lowered LDL by 0.23 to 0.42 mmol/L more than butterAdults in 54 randomised trialsButter compared with other oils and solid fats

6

Other 3

●

Combined cardiovascular events (saturated fat in general)

Fewer events when saturated fat was reduced in trials

Heart attacks, strokes and similar events counted together.

Moderate certainty
Results and what it means

Why it was measured

The outcome that matters most for heart health.

Statistical vs. clinical meaning

Supports the advice to swap saturated fat for unsaturated fat; it does not test butter itself.

Safety implication

None specific.

StudyResultPeopleProduct
1RR 0.79 (95% CI 0.66-0.93) over at least two yearsAbout 53,300 adults in 11 trialsReduced saturated fat from any source, not butter alone

1

●

All-cause mortality

Very slightly higher with more butter in trials

Death from any cause during follow-up.

Very low certainty
Results and what it means

Why it was measured

The broadest health outcome.

Statistical vs. clinical meaning

A tiny, borderline difference seen in observational data.

Safety implication

None specific.

StudyResultPeopleProduct
3RR 1.01 (95% CI 1.00-1.03) per 14 g a dayAdults in 9 country-specific cohortsUsual butter intake

3

●

New cases of type 2 diabetes

Very slightly lower with more butter in trials

How many people develop type 2 diabetes during follow-up.

Very low certainty
Results and what it means

Why it was measured

A key long-term metabolic outcome.

Statistical vs. clinical meaning

A small observational link; not proof of prevention.

Safety implication

None specific.

StudyResultPeopleProduct
3RR 0.96 (95% CI 0.93-0.99) per 14 g a dayAdults in 11 country-specific cohortsUsual butter intake

3

Safety

What studies and official sources say about side effects, medicines and who should check first. Each point shows what kind of evidence it comes from.

Main points to know 3
  • Butter is a milk product: do not eat it with a cows' milk allergy. The NHS lists cows' milk among the most common food allergies. Butter is made from milk, so people with a milk allergy should get advice from an allergist before eating it. Swelling of the face or throat or trouble breathing is an emergency. Authoritative guidance 8
  • Butter is high in saturated fat and raises LDL cholesterol. USDA lists about 51 g of saturated fat per 100 g, or 7.3 g in a tablespoon. Trials show butter raises LDL more than most liquid plant oils. The NHS lists butter among foods high in saturated fat. Controlled trial 6 11 13
  • Unpasteurised butter is on the NHS 'avoid in pregnancy' list. The NHS says pasteurised butter is safe in pregnancy but unpasteurised butter should be avoided because of listeria. Most butter in UK supermarkets is pasteurised, and the label tells you. Authoritative guidance 10
Side effects 3
EffectHow oftenSeverity and recoveryEvidence
Higher LDL cholesterol compared with unsaturated oils
A change in a blood marker, not a measured heart attack.
Not establishedmoderate for people with high cholesterol or heart disease
LDL falls when saturated fat is replaced with unsaturated fat in trials.
Controlled trial 6
Allergic reaction in people allergic to cows' milk
No source read gives how much milk protein butter holds.
Not establishedmild to life-threatening
Depends on the reaction.
Authoritative guidance 8
Lactose-intolerance symptoms such as tummy pain, bloating or diarrhoea
The NHS lists butter among dairy foods; no source read gives butter's lactose content, so how much lactose it holds is not stated here.
Not establishedmild to moderate
The NHS says symptoms can be prevented by eating smaller portions of lactose-containing foods or avoiding them.
Authoritative guidance 9
Liver

No liver injury linked to eating butter was found in the sources read. LiverTox was not checked.

How often. No frequency found.

This is a safety connection. It is not evidence that Butter supports liver health.

Medicines and supplements 2
WithWhy it mattersImportanceEvidenceWhat to do
Prescription and over-the-counter medicines
prescription
No source read describes a medicine interaction with butter as food.None found Not enough evidence A pharmacist can check your own medicines.
Vitamin A supplements, fish liver oil and liver
supplement-or-food
Butter contains preformed vitamin A (retinol), which adds to vitamin A from other sources.The NHS says an average over 1,500 micrograms a day over many years may affect bones. One tablespoon of butter provides about 97 micrograms (USDA), well below that.Authoritative guidance Low certainty 12 13Count butter with other sources if you take vitamin A supplements.
Who should check first 2
SituationAdviceEvidence
Cows' milk allergyAvoid butter unless an allergist has told you otherwise, and follow your own emergency plan.Authoritative guidance 8
Pregnancy: unpasteurised butterChoose pasteurised butter; the NHS lists unpasteurised butter as a food to avoid.Authoritative guidance 10
Overdose, product quality and regulators

Summary. Butter is an ordinary food. The concerns in the sources read are saturated fat and cholesterol, milk allergy, and germs in unpasteurised products.

Animal. Not reviewed.

Human doses studied. Cohort studies of usual intake found no clear link with heart disease or stroke and a very small link with all-cause death.

High dose or long term signals. A very small link with higher all-cause death (RR 1.01) in cohort studies; not proof of harm.

Overdose response. Not found.

Genotoxicity. Not reviewed.

The main food-safety point found is raw (unpasteurised) milk products. Contaminants such as dioxins or pesticide residues in butter were not looked up.

Unpasteurised butter and listeria (NHS pregnancy list). The NHS lists unpasteurised butter among foods to avoid in pregnancy and says unpasteurised dairy foods may contain listeria, which can cause listeriosis. 10

Natural trans fat. USDA lists about 3.3 g total trans fat per 100 g of butter. The FDA says trans fat also occurs naturally in milk, butter, cheese and meat from ruminant animals and that its actions on partially hydrogenated oils have not affected those natural sources. 13 7

BodyActionDate
NHS (United Kingdom)Pasteurised butter is safe in pregnancy; unpasteurised butter is a food to avoid. sourcePage last reviewed 15 June 2026
NHS (United Kingdom)Saturated fat guidance: no more than 30 g a day for the average man and 20 g for the average woman; butter listed as a high-saturated-fat food. sourcePage last reviewed 19 June 2023
US FDA (United States)Trans fat from partially hydrogenated oils is being removed from food; the actions do not affect trans fat that occurs naturally in dairy and meat. sourceNot shown in the page text read
American Heart Association (United States)Advisory: replacing saturated fat with unsaturated fat, especially polyunsaturated fat, lowers cardiovascular disease. source2017
When to get medical help
  • Swelling of the lips, face, tongue or throat
  • Trouble breathing, wheezing or a tight throat
  • Fainting, dizziness or a pale, floppy feeling after eating
  • Widespread hives or repeated vomiting soon after eating
  • Fever, stomach cramps or diarrhoea after unpasteurised dairy, especially in pregnancy: contact a doctor

Stop using the product and contact a clinician or emergency service. In the US, Poison Control is 1-800-222-1222.

General information only, not medical advice. Ask a clinician or pharmacist before use, especially with medicines, in pregnancy or with a health condition. See the Natural Remedy Safety guide.

Frequently asked questions

Is butter bad for your heart?

In trials, butter raises LDL cholesterol more than most liquid plant oils. In large eating-habit studies, butter was not clearly linked with heart disease or stroke. Official advice still prefers unsaturated oils.

6 3 5

Does butter raise cholesterol?

It raises LDL cholesterol more than olive, canola, sunflower and several other oils in a pooled analysis of 54 trials. A Nordic review agreed.

6 4

Is butter better for you than oils?

For LDL cholesterol, the oils tested did better than butter. The authors and the American Heart Association support replacing saturated fat with unsaturated fat.

6 5

Is butter better than margarine?

The sources we read compare butter with oils, not with modern spreads, so we cannot answer this here. See the margarine and spreads page.

What nutrition does butter have?

A tablespoon of salted butter has about 102 calories, 11.5 g fat, 7.3 g saturated fat, 31 mg cholesterol, 91 mg sodium and 97 micrograms vitamin A (USDA). Almost no protein or carbohydrate.

13

Does butter have trans fat?

Yes, a small natural amount: about 3.3 g per 100 g (USDA). The FDA says trans fat that occurs naturally in dairy and meat is not covered by its action on industrial trans fat.

13 7

Can I eat butter with a milk allergy?

Butter is made from milk, and the NHS lists cows' milk among common allergens. Ask an allergist. Call emergency services for swelling of the face or throat or trouble breathing.

8

Is butter safe in pregnancy?

The NHS says pasteurised butter is safe to eat and unpasteurised butter should be avoided because of listeria. Check the label.

10

Is butter OK if I am lactose intolerant?

The NHS lists butter among dairy foods that contain lactose and says smaller portions or avoiding them can prevent symptoms. We found no source giving butter's exact lactose content.

9

Does butter lower the risk of diabetes?

Eating-habit studies show a tiny link with lower diabetes risk (RR 0.96 per tablespoon a day). That is an association, not proof, and the certainty is very low.

3 4

Is grass-fed butter healthier?

We did not read a source on this question, so we make no claim.

Does the vitamin A in butter matter?

Butter gives a small amount of vitamin A. The NHS says averaging more than 1,500 micrograms a day over many years from food and supplements together may affect bones, so butter counts alongside other sources.

12 13

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Editorial transparency
Written by
AlternativeMed editorial team. Research compiled with AI assistance, then checked against the sources listed.
Medical review
None. This page has not been reviewed by a physician or pharmacist.
First published
2026-10-26
Last substantive update
2026-10-26
How we research
We started from our existing butter summary, kept its USDA nutrition figures (taken from a saved copy of the USDA data), re-read PubMed abstracts for the reviews cited and re-read the NHS and FDA pages. CDC and food-allergy-charity pages could not be opened and are flagged. Only abstracts were read for studies.
How we rate evidence
See "How we rate evidence" in the Evidence tab.
Independence
No product is promoted on this page. No affiliate links are shown. One review author lists consulting for an avocado industry board; this is stated in the study record.
Sources 13

Each source was opened and checked. Where we read only the abstract, it says so. The small numbers in the text point here.

  1. Hooper L, Martin N, Jimoh OF, et al.. Reduction in saturated fat intake for cardiovascular disease.. Cochrane Database Syst Rev. 2020. PMID 32428300. DOI 10.1002/14651858.CD011737.pub2. (abstract)
  2. Neuenschwander M, Stadelmaier J, Eble J, et al.. Substitution of animal-based with plant-based foods on cardiometabolic health and all-cause mortality: a systematic review and meta-analysis of prospective studies.. BMC Med. 2023. PMID 37968628. DOI 10.1186/s12916-023-03093-1. (abstract)
  3. Pimpin L, Wu JH, Haskelberg H, Del Gobbo L, Mozaffarian D. Is Butter Back? A Systematic Review and Meta-Analysis of Butter Consumption and Risk of Cardiovascular Disease, Diabetes, and Total Mortality.. PLoS One. 2016. PMID 27355649. DOI 10.1371/journal.pone.0158118. (abstract)
  4. Rosqvist F, Niinisto S. Fats and oils - a scoping review for Nordic Nutrition Recommendations 2023.. Food Nutr Res. 2024. PMID 38370114. DOI 10.29219/fnr.v68.10487. (abstract)
  5. Sacks FM, Lichtenstein AH, Wu JHY, et al.. Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association.. Circulation. 2017. PMID 28620111. DOI 10.1161/CIR.0000000000000510. (abstract)
  6. Schwingshackl L, Bogensberger B, Bencic A, et al.. Effects of oils and solid fats on blood lipids: a systematic review and network meta-analysis.. J Lipid Res. 2018. PMID 30006369. DOI 10.1194/jlr.P085522. (abstract)
  7. . US FDA: Trans Fat. . . (full-text)
  8. . NHS: Food allergy. . . (full-text)
  9. . NHS: Lactose intolerance. . . (full-text)
  10. . NHS: Foods to avoid in pregnancy. . . (full-text)
  11. . NHS: Eat less saturated fat. . . (full-text)
  12. . NHS: Vitamin A. . . (full-text)
  13. . USDA FoodData Central: Butter, salted (FDC 173410, SR Legacy, April 2018). . . (partial)

Where to buy

Check the label first. Whatever you buy, look for these:

  • Cold-pressed or refined, to match how you cook
  • A harvest or best-by date and a dark glass or tin container
  • The oil's origin and any testing statement
  • Smoke point for the way you cook

Talk to a pharmacist or doctor before you start any supplement, especially if you take medicines. See the Safety tab for interactions.

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Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.