
Herbal Teas & Extracts · Tea blend
Genmaicha (Green Tea with Roasted Rice)
Camellia sinensis and Oryza sativa · also called Green tea with roasted rice, brown rice green tea, genmai-cha (romanised Japanese).
Genmaicha is green tea blended with roasted rice. The green tea part gives it caffeine, and people drink it as an everyday tea. We found no studies of genmaicha itself; the research is on plain green tea and gives small or uncertain effects. The main cautions are caffeine (especially in pregnancy), a little acrylamide formed when grain is roasted, and that green tea extract capsules, a different product, have rare serious liver reports.
General information, not medical advice. Last substantive update · Not medically reviewed. A named clinician has not signed off on this page. How this page is made
About Genmaicha (Green Tea with Roasted Rice)
Genmaicha is green tea blended with roasted rice. We found no studies of genmaicha or of roasted rice tea in people. The research on green tea gives small or uncertain results for heart risk factors, almost nothing for weight or cancer, and no effect on blood sugar. The main cautions are caffeine from the tea part, acrylamide formed by roasting, and the usual green tea points on iron, medicines and pregnancy. Extract capsules are a separate product with a liver warning.
What it is
Genmaicha is a blend of two plants. The tea part is the leaf of Camellia sinensis (tea family, Theaceae). The other part is roasted rice, the grain of Oryza sativa (grass family, Poaceae). GBIF accepts both names. For green tea the leaves are steamed or pan fried and dried but not fermented.
The tea part brings caffeine, L-theanine and catechins, mainly EGCG. The rice part is a cooked grain, not a herb. We read no source on how much of each is in a typical blend, or on where the blend came from.
Tea or extract?
A cup of tea is a weak water extract of the leaf. A capsule or tablet packs catechins into a concentrated pill. The liver warnings and many trial results belong to the concentrated form. A systematic review of 159 human studies found liver events came from concentrated, catechin-rich preparations taken in large single doses, not from brewed tea or extracts used in drinks or food. Do not carry results from one form to the other, and do not assume green tea results apply to a blend that is part rice.
Roasted rice and acrylamide
Acrylamide forms naturally in starchy food during high-heat cooking, including roasting. It comes from sugars and an amino acid called asparagine (EFSA). Japanese food analyses found it in roasted barley tea grain and in roasted green tea (hoji-cha), and a lab study found it in roasted brown rice for tea, with less when the rice was germinated first.
These were dry roasted products, not brewed cups, and none was genmaicha. One analysis noted that foods holding more water tended to have less acrylamide than dry foods. How much reaches a cup of genmaicha is not known.
What the research shows
Nothing was found on genmaicha itself. For green tea, Cochrane found small falls in cholesterol and blood pressure from a few trials, but the results were not stable and no trial reported heart attacks or strokes. A later review of 14 shorter tea trials found no effect on blood fats or pressure. Outside Japan green tea gave almost no weight loss.
Cochrane found inconsistent, low-certainty results for cancer. In eight Japanese cohorts, heavy drinkers had lower death rates, which shows a link and not a cause. For thinking, one review of mixed studies suggests a role for caffeine and L-theanine together. Trials of green tea supplements in type 2 diabetes found no effect on blood sugar.
Regulators and status
The EMA has an EU herbal monograph and assessment report for green tea leaf; only the web page was read, and it does not cover genmaicha. EFSA judged traditional green tea infusions generally safe at European intakes, and EFSA's acrylamide page covers roasted foods in general. NCCIH notes that the FDA approved a green tea extract ointment as a prescription drug for genital warts, a topical medicine and not a drink or supplement.
At a glance
Traditional uses history, not proof
- Genmaicha is drunk as an everyday tea. We read no source on its history, so none is given here.
- The tea part comes from a plant first grown in China; NCCIH says tea has been used for health purposes for about 3,000 years. That is about tea, not this blend.
- The EU has a herbal monograph for green tea leaf (area listed: fatigue and weakness). It covers green tea, not genmaicha.
Studied for research
- Genmaicha itself: insufficient evidence (no studies found)
- Cholesterol (green tea), low
- Blood pressure (green tea), low
- Body weight (green tea), low
- Heart disease and death rates in drinkers (green tea, an association), low
- Attention, memory and mood (green tea), low
- Cancer risk (green tea), insufficient
- Dementia risk (green tea), very low
- Blood sugar in type 2 diabetes (green tea), no effect found (against)
Main compounds
- Catechins, mainly EGCG (from the tea leaf)
- Caffeine (from the tea leaf)
- L-theanine (from the tea leaf)
- Acrylamide, a chemical formed when grain and tea are roasted
- Rice starch, sugars and amino acids, changed by roasting
Common forms
- Green tea leaf blended with roasted rice (the tea itself)
- Genmaicha tea bags and loose blends
- Green tea extract capsules (a different product, with a liver warning)
Research links: NCCIH: Green Tea · EFSA: Acrylamide · EFSA opinion on green tea catechins (abstract) · Lab study of roasted brown rice for tea, including acrylamide (abstract) · LiverTox: Green Tea (summary) · Research Library · Genes & Biomarkers Library
What it is and its history
- Accepted scientific name
- Genmaicha (blend)
- Common names
- Genmaicha (Japanese (romanised)); Green tea with roasted rice (English)
- Family or group
- Theaceae (tea) and Poaceae (rice, the grass family)
- Classification
- Plantae
- Native range
- Not checked.
- Habitat
- Not checked.
- What it looks like
- Leaves: Tea leaf is the part used from the tea plant (NCCIH).; Fruit: Rice grain is the part used from the rice plant (not described in the sources read).
- Cultivation
- Not checked.
- Harvest and processing
- Green tea leaves are steamed, pan fried and dried but not fermented (NCCIH). The rice is roasted; a lab study roasted brown rice for tea and found roasting made aroma compounds and phenolics and used up some sugars and amino acids (Kim 2021).
- Look-alikes and adulterants
- Name: Green tea extract and other teas; Note: Genmaicha is a drink. Extract capsules are concentrated and behave differently. Plain green tea, hojicha (roasted green tea) and barley tea are other products.
- Sustainability and conservation
- Not checked.
Photographs

Traditional use and history history, not clinical proof
| Tradition or era | Documented use | Source |
|---|---|---|
| Origin of the blend | No source read describes the history of genmaicha, so none is given here. | s-nccih-green-tea |
| Tea plant, China | NCCIH says tea was first cultivated in China thousands of years ago and used for health purposes for about 3,000 years. This is about tea, not the blend. | s-nccih-green-tea |
| European regulator | EMA has an EU herbal monograph and assessment report for green tea leaf (therapeutic area listed as fatigue and weakness). The text was not read. It covers green tea, not genmaicha. | s-ema-hmpc-green-tea |
Traditional use shows how it was used. It does not show that it works or is safe today.
What is inside, and how it may work
What it contains and how those compounds act in cells and animals. Laboratory and animal mechanisms are not proven effects in people.
Main compounds
| Compound | Family | Where it is concentrated | Activity studied | Level of evidence |
|---|---|---|---|---|
| Epigallocatechin gallate (EGCG) PubChem 65064 | catechin (polyphenol) | Leaf The main catechin in green tea (EFSA). Not measured in genmaicha in the sources read. | Liver effects at high supplement doses; other actions not established in the sources read. 32 4 | Human data |
| Caffeine PubChem 2519 | purine alkaloid | Leaf Not measured in genmaicha in the sources read. The caffeine comes from the tea leaf part. | Stimulant; see Safety tab. 33 27 | Human data |
| L-theanine PubChem 439378 | amino acid | Leaf Not given in the sources read. | Reviewers link benefits for attention to caffeine and L-theanine together. 34 15 16 | Human data |
| Tannins and other polyphenols | polyphenols | Leaf and stem Not given. | Tea polyphenols lower iron absorption (radio-iron study, black and herb teas). 16 9 | Human data |
| Acrylamide | process contaminant formed by heat | Roasted grain and roasted tea Roasted barley tea grain 200 to 600 micrograms per kg; roasted foods incl. hoji-cha and mugi-cha 116 to 567 ng/g (dry products). Not measured in genmaicha. | EFSA: dietary acrylamide potentially increases cancer risk. 30 22 18 24 14 | Food analysis and regulator |
| Rice starch, sugars, amino acids and phenolics (after roasting) | grain components | Roasted rice grain Germination raised reducing sugars and free amino acids in brown rice for tea; roasting lowered them and made volatile compounds and phenolics. | Aroma and colour; no health effect shown. 14 | Food analysis |
Mechanisms, receptors and pathways
| Target or pathway | Gene or receptor | What was found | Level |
|---|---|---|---|
| Liver injury from concentrated EGCG | UGT1A4 and COMT variants (secondary trial analysis); an immune-related gene variant (NCCIH) | Toxicology review: liver is the target organ in lab studies, tied to large single doses and fasting and to EGCG content. In a secondary trial analysis, women with the UGT1A4 A/C variant had larger ALT rises on high-dose extract. 8 2 28 | Lab and human |
| Caffeine plus L-theanine on attention | n/a | Cognitive benefits were seen with caffeine and L-theanine together and less with either alone. 15 | Human review |
| Iron absorption | n/a | Tea polyphenols reduce absorption of non-haem iron in a dose-related way (radio-iron study of black and herb teas). 9 | Human data |
| Acrylamide formation | n/a | Acrylamide forms from sugars and asparagine at high heat (EFSA). In roasted brown rice for tea, germinating first lowered acrylamide because of less asparagine (Kim 2021). 30 14 | Food chemistry |
Absorption, metabolism and elimination
- Absorption
- Not covered in the sources read.
- Distribution
- Not covered.
- Metabolism
- A secondary trial analysis links the enzymes COMT and UGT1A4 with liver enzyme changes on high-dose extract.
- Elimination
- Not covered.
- Bioavailability
- Not covered.
Isolated compounds versus whole extracts
Brewed tea, powdered leaf (matcha), liquid extracts and concentrated EGCG capsules are different products. EFSA estimates that supplements can deliver far more EGCG than infusions do; liver warnings come from the concentrated form. Genmaicha is a brewed drink that is part tea leaf and part roasted rice, and no study has measured how its contents compare with plain green tea.
Nutritional composition
Neither part is described as a source of essential nutrients in the sources read. The tea part contains caffeine, L-theanine, catechins and tannins. The roasted rice part holds starch, sugars and amino acids that change with roasting; how much reaches the drink is not stated.
5 low certainty1 very low certainty2 not enough evidence1 evidence against
What was looked at
The 9 benefits and uses checked for Genmaicha (Green Tea with Roasted Rice), each with how strong the evidence is. Tap one to open it.
- Genmaicha itself (green tea with roasted rice)Not enough evidence
- Cholesterol (green tea research)Low certainty
- Blood pressure (green tea research)Low certainty
- Body weight (green tea research)Low certainty
- Cancer risk (green tea research)Not enough evidence
- Heart disease and death rates in drinkers (green tea research)Low certainty
- Attention, memory and mood (green tea research)Low certainty
- Dementia and memory loss risk (green tea research)Very low certainty
- Blood sugar in type 2 diabetes (green tea research)Evidence against
Lab markers tracked in the studies
LDL cholesterolSystolic blood pressureBody weightDeath from any causeHbA1cAttention and memory tests
What is Genmaicha (Green Tea with Roasted Rice) good for?
The main studied uses and how strong the human evidence is for each. "Low" is the best rating found for any benefit, and several are lower. All of it is about green tea, because genmaicha itself has not been studied. Genmaicha is not a replacement for medicine.
Benefits, one by one
Each card is a research question, not a promise. Tap a goal to filter. Open a card to see the studies, doses and limits.
Genmaicha itself (green tea with roasted rice)
Not enough evidenceWe found no trial of genmaicha and no human study of its roasted rice. Everything below is green tea research, which covers only the tea part of the blend.
1 studiesNot applicable.
Studies, doses and limits
What the trials found
PubMed searches for genmaicha found no clinical study of the drink. A search for roasted rice tea found food-chemistry papers (sugars, amino acids, acrylamide), not studies in people.
Results
No human results for genmaicha or for roasted rice tea.
Why this rating
No studies of the blend exist in the sources read.
Limits
Green tea results may not carry over to a blend that is part rice.
Why researchers looked
People drink genmaicha as an everyday green tea, so the natural question is whether it behaves like green tea.
Traditional use
Not described in the sources read.
Proposed mechanism Not established
No mechanism has been studied for genmaicha. The tea part contains catechins, caffeine and L-theanine; the roasted rice part is a cooked grain.
A proposed mechanism does not show that the effect happens in people.
See the Safety tab: caffeine from the tea part, acrylamide from roasting, and the usual green tea cautions.
Cholesterol (green tea research)
Low certaintyThese results are for green tea, not genmaicha. Pooled trials of green tea drinks and extracts show a small average fall in total and LDL cholesterol. Two reviews disagree, and most of the trial data comes from extract or mixed products, so the result for a cup of tea is uncertain. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known.
4 studiesMixed: drinks and extracts. Not a drink-only result.
Studies, doses and limits
What the trials found
A 2011 meta-analysis of 14 trials (1,136 people) of green tea drinks or extracts found a small fall in total and LDL cholesterol and no change in HDL. A Cochrane review of 7 green tea trials found larger falls that were not stable when checked. A 2020 review of 14 shorter trials of green or black tea (4 to 24 weeks) found no significant effect. NCCIH says most trials tested extract supplements, not the drink.
Results
Total cholesterol -7.20 mg/dL (95% CI -8.19 to -6.21) and LDL -2.19 mg/dL (-3.16 to -1.21) in the 2011 pooled trials; Cochrane green tea: total -0.62 mmol/L and LDL -0.64 mmol/L, not stable to sensitivity analysis; 2020 review: no significant change.
Effect sizes as reported
Small average falls; reviewers disagree on whether they are real in short trials.
Why this rating
Pooled drinks and extracts, small trials, results not stable, a later review found no effect.
Form and dose studied
Mixed: drinks and extracts. Not a drink-only result.
Who was studied
Healthy adults and adults at higher risk, mostly short trials.
Limits
Product types differ; most trials are short; no heart attack or stroke outcomes.
Why researchers looked
High LDL cholesterol is a risk factor for heart disease, and green tea catechins are often said to help.
Traditional use
Not described in the sources read.
Proposed mechanism Not established
No mechanism was established in the sources read.
A proposed mechanism does not show that the effect happens in people.
Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.
Blood pressure (green tea research)
Low certaintyThese results are for green tea, not genmaicha. Reviews find a very small average fall in blood pressure, with big differences between studies. One review of short trials found no effect. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known.
3 studiesGreen tea supplementation; the 2025 abstract does not separate drink …
Studies, doses and limits
What the trials found
A 2025 meta-analysis of 36 trials of green tea supplementation found average falls of about 1 mmHg in both systolic and diastolic pressure with very high differences between trials. The Cochrane review found larger falls (about 3 mmHg) from a small number of green tea trials that were not stable. A 2020 review of 14 trials of green or black tea (4 to 24 weeks) found no significant effect.
Results
Systolic -1.08 mmHg (95% CI -1.98 to -0.18), diastolic -1.09 mmHg (-1.67 to -0.50) in 36 trials; Cochrane green tea systolic -3.18 mmHg, diastolic -3.42 mmHg, unstable; 2020 review: no significant effect.
Effect sizes as reported
About 1 to 3 mmHg at most.
Why this rating
Very large differences between trials (I2 74 to 85 percent), unstable Cochrane result, one review with no effect.
Form and dose studied
Green tea supplementation; the 2025 abstract does not separate drink from extract.
Who was studied
Adults, with stronger effects in people who started with raised blood pressure.
Limits
Heterogeneity; mixed forms; small average change that may not matter to health.
Why researchers looked
High blood pressure is a leading risk factor for heart disease and stroke.
Traditional use
Not described in the sources read.
Proposed mechanism Not established
No mechanism was established in the sources read.
A proposed mechanism does not show that the effect happens in people.
Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab. The authors call green tea a complementary approach, not a treatment for high blood pressure.
Body weight (green tea research)
Low certaintyThese results are for green tea, not genmaicha. A Cochrane review found almost no weight loss from green tea outside Japan. The Japanese trials were too different to combine and ranged from little change to a few kilograms. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known.
2 studiesGreen tea preparations, drinks and extracts.
Studies, doses and limits
What the trials found
The review included trials of at least 12 weeks in overweight or obese adults: six outside Japan (532 people) and eight in Japan (1,030 people).
Results
Outside Japan: weight -0.04 kg (95% CI -0.5 to 0.4), BMI -0.2 kg/m2, waist -0.2 cm; none significant. Japanese trials ranged from -0.2 to -3.5 kg and could not be pooled.
Effect sizes as reported
No meaningful change outside Japan.
Why this rating
Short trials of 12 to 13 weeks, many preparation types, results differ by region.
Form and dose studied
Green tea preparations, drinks and extracts.
Who was studied
Overweight and obese adults.
Limits
Not a drink-only result; short.
Why researchers looked
Green tea contains catechins and caffeine, which reviewers say are believed to raise energy use.
Traditional use
NCCIH says green tea and extracts are promoted for weight loss.
Proposed mechanism Hypothesis
The Cochrane reviewers state a belief that catechins and caffeine may raise energy metabolism; they say the efficacy remains unclear.
A proposed mechanism does not show that the effect happens in people.
Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.
Cancer risk (green tea research)
Not enough evidenceThese results are for green tea, not genmaicha. A large Cochrane review found inconsistent, low-certainty results. It does not show that green tea prevents cancer. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known.
2 studiesExtract in trials; drinking in observational studies.
Studies, doses and limits
What the trials found
The review used 142 studies: 11 trials of green tea extract (1,795 people) and 131 observational studies (over 1,100,000 people).
Results
Extract trials: prostate cancer RR 0.50 (95% CI 0.18 to 1.36), gynaecological RR 1.50 (0.41 to 5.48), skin RR 1.00 (0.06 to 15.92). Observational highest versus lowest intake: cancer incidence RR 0.83 (0.65 to 1.07); cancer death RR 0.99 (0.91 to 1.07). Results conflicted between study designs for some cancers.
Effect sizes as reported
Intervals include no effect.
Why this rating
Low-certainty and inconsistent results; mostly observational; Asian populations.
Form and dose studied
Extract in trials; drinking in observational studies.
Who was studied
Adults, mostly in Asia.
Limits
Cannot show cause; trials used extract.
Why researchers looked
Lab studies have suggested catechins may slow cancer cell growth; population studies have asked whether tea drinkers get less cancer.
Traditional use
Not described in the sources read.
Proposed mechanism Lab only
Cochrane notes that laboratory studies have suggested catechins may inhibit cancer cell growth. This is lab work and not shown in people.
A proposed mechanism does not show that the effect happens in people.
Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.
Heart disease and death rates in drinkers (green tea research)
Low certaintyThese results are for green tea, not genmaicha. In Japan, people who drank five or more cups a day had somewhat lower death rates than people who drank less than one. This is an association and does not show tea caused it. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known.
2 studiesGreen tea as a drink.
Studies, doses and limits
What the trials found
A pooled analysis of eight Japanese cohorts followed 313,381 people for a mean 17.3 years.
Results
Five or more cups a day versus less than one: all-cause death HR 0.90 (0.87 to 0.94) in men and 0.82 (0.74 to 0.90) in women; heart disease HR 0.82 and 0.75; stroke-type HR 0.76 and 0.78. In women only, total cancer death HR 0.89 (0.83 to 0.96) at 1 to 2 cups.
Effect sizes as reported
Roughly 10 to 18 percent lower all-cause death among the heaviest drinkers.
Why this rating
Observational; healthier lifestyle among drinkers cannot be ruled out; Japanese data.
Form and dose studied
Green tea as a drink.
Who was studied
Japanese adults.
Limits
Self-reported intake; cannot show cause; may not apply outside Japan.
Why researchers looked
Green tea is part of daily life in Japan, so large cohorts can compare heavy and light drinkers.
Traditional use
NCCIH notes that lower heart disease risk has been linked to green tea in Asian but not Western groups.
Proposed mechanism Not established
Not established. Observational data cannot identify a mechanism.
A proposed mechanism does not show that the effect happens in people.
Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.
Attention, memory and mood (green tea research)
Low certaintyThese results are for green tea, not genmaicha. A systematic review found signs of better attention and memory and less anxiety, mostly in small or short studies. The effect seems to come from caffeine and L-theanine together. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known.
1 studiesGreen tea, green tea extract, L-theanine and EGCG.
Studies, doses and limits
What the trials found
Mancini 2017 reviewed 21 studies (4 randomised trials, 12 crossover studies, 4 cross-sectional studies, 1 cohort) on green tea, green tea extract, L-theanine and EGCG.
Results
The reviewers report evidence of less anxiety, better memory and attention and brain-scan changes with working memory. The abstract gives no numbers.
Effect sizes as reported
Not given in the abstract.
Why this rating
Mixed products (drink, extract, isolated L-theanine), many short or single-dose studies, no numbers in abstract.
Form and dose studied
Green tea, green tea extract, L-theanine and EGCG.
Who was studied
Mostly healthy adults.
Limits
Not a drink-only result; PubMed only; reviewers own quality scores.
Why researchers looked
Green tea contains caffeine and L-theanine, and people drink it for alertness with calm.
Traditional use
Not described in the sources read.
Proposed mechanism Human study observation
The reviewers say the effect cannot be put down to one ingredient: benefits for cognition appeared with caffeine and L-theanine together and were smaller with either alone.
A proposed mechanism does not show that the effect happens in people.
Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.
Dementia and memory loss risk (green tea research)
Very low certaintyThese results are for green tea, not genmaicha. Observational studies lean towards lower risk in green tea drinkers, but they are few and mixed, and cannot show that tea is the reason. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known.
1 studiesGreen tea as a drink.
Studies, doses and limits
What the trials found
A 2019 systematic review found 3 cohort and 5 cross-sectional studies.
Results
One cohort and three cross-sectional studies supported a benefit, one cohort and one cross-sectional study partly supported it, and one of each found no link.
Effect sizes as reported
Not given in the abstract.
Why this rating
Eight observational studies, mixed results, cannot show cause.
Form and dose studied
Green tea as a drink.
Who was studied
Mostly Asian adults.
Limits
Observational; small number of studies.
Why researchers looked
Population studies in Asia asked whether regular green tea drinkers keep their memory longer.
Traditional use
Not described in the sources read.
Proposed mechanism Not established
Not established.
A proposed mechanism does not show that the effect happens in people.
Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.
Blood sugar in type 2 diabetes (green tea research)
Evidence againstThese results are for green tea, not genmaicha. A meta-analysis of 14 trials found no significant effect of green tea supplements on blood sugar measures in people with type 2 diabetes. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known.
1 studiesGreen tea supplementation; type not stated in the abstract.
Studies, doses and limits
What the trials found
A 2021 meta-analysis pooled 14 randomised trials in people with type 2 diabetes.
Results
No significant effect on fasting glucose, fasting insulin, HbA1c or insulin resistance (HOMA-IR).
Effect sizes as reported
No significant effect.
Why this rating
One meta-analysis of 14 trials found no effect; the abstract does not give the product type; small trials, so no effect is not proof of none.
Form and dose studied
Green tea supplementation; type not stated in the abstract.
Who was studied
Adults with type 2 diabetes.
Limits
Small trials; form unclear.
Why researchers looked
Catechins have been proposed to affect blood sugar and insulin.
Traditional use
Not described in the sources read.
Proposed mechanism Not established
Not established in the source read.
A proposed mechanism does not show that the effect happens in people.
Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab. People taking diabetes medicines should speak to their prescriber before using any supplement.
Connections to the rest of health
How Genmaicha (Green Tea with Roasted Rice) connects to the rest of our health knowledge graph. Every link says what kind of connection it is. A safety link (for example to the liver) is a warning, not a benefit. A study that merely mentions a topic never creates a benefit link.
Explore every connection: goals, body systems, organs, symptoms, genes
A. Wellness goals
| Connected to | Kind of connection | Evidence status | Context | Studies |
|---|---|---|---|---|
| Heart Health | Not enough evidence | Genmaicha itself (green tea with roasted rice): We found no trial of genmaicha and no human study of its roasted rice. Everything below is green tea research, which covers only the tea part of the blend. | 14 | |
| Energy Vitality | Not enough evidence | Genmaicha itself (green tea with roasted rice): We found no trial of genmaicha and no human study of its roasted rice. Everything below is green tea research, which covers only the tea part of the blend. | 14 | |
| Cholesterol Balance | Low certainty | Cholesterol (green tea research): These results are for green tea, not genmaicha. Pooled trials of green tea drinks and extracts show a small average fall in total and LDL cholesterol. Two reviews disagree, and most of the trial data comes from extract or mixed products, so the result for a cup of tea is uncertain. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 25 6 10 28 | |
| Heart Health | Low certainty | Cholesterol (green tea research): These results are for green tea, not genmaicha. Pooled trials of green tea drinks and extracts show a small average fall in total and LDL cholesterol. Two reviews disagree, and most of the trial data comes from extract or mixed products, so the result for a cup of tea is uncertain. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. Blood pressure (green tea research): These results are for green tea, not genmaicha. Reviews find a very small average fall in blood pressure, with big differences between studies. One review of short trials found no effect. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 25 6 10 28 20 | |
| Blood Pressure Support | Low certainty | Blood pressure (green tea research): These results are for green tea, not genmaicha. Reviews find a very small average fall in blood pressure, with big differences between studies. One review of short trials found no effect. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 20 6 10 | |
| Weight Management | Low certainty | Body weight (green tea research): These results are for green tea, not genmaicha. A Cochrane review found almost no weight loss from green tea outside Japan. The Japanese trials were too different to combine and ranged from little change to a few kilograms. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 12 28 | |
| Preventive Wellness | Not enough evidence | Cancer risk (green tea research): These results are for green tea, not genmaicha. A large Cochrane review found inconsistent, low-certainty results. It does not show that green tea prevents cancer. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 5 28 | |
| Heart Health | Biological association | Low certainty | Heart disease and death rates in drinkers (green tea research): These results are for green tea, not genmaicha. In Japan, people who drank five or more cups a day had somewhat lower death rates than people who drank less than one. This is an association and does not show tea caused it. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 1 28 |
| Longevity | Biological association | Low certainty | Heart disease and death rates in drinkers (green tea research): These results are for green tea, not genmaicha. In Japan, people who drank five or more cups a day had somewhat lower death rates than people who drank less than one. This is an association and does not show tea caused it. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 1 28 |
| Mental Clarity | Low certainty | Attention, memory and mood (green tea research): These results are for green tea, not genmaicha. A systematic review found signs of better attention and memory and less anxiety, mostly in small or short studies. The effect seems to come from caffeine and L-theanine together. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 15 | |
| Better Focus | Low certainty | Attention, memory and mood (green tea research): These results are for green tea, not genmaicha. A systematic review found signs of better attention and memory and less anxiety, mostly in small or short studies. The effect seems to come from caffeine and L-theanine together. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 15 | |
| Memory Support | Low certainty | Attention, memory and mood (green tea research): These results are for green tea, not genmaicha. A systematic review found signs of better attention and memory and less anxiety, mostly in small or short studies. The effect seems to come from caffeine and L-theanine together. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 15 | |
| Brain Health | Low certainty | Attention, memory and mood (green tea research): These results are for green tea, not genmaicha. A systematic review found signs of better attention and memory and less anxiety, mostly in small or short studies. The effect seems to come from caffeine and L-theanine together. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 15 | |
| Brain Health | Biological association | Very low certainty | Dementia and memory loss risk (green tea research): These results are for green tea, not genmaicha. Observational studies lean towards lower risk in green tea drinkers, but they are few and mixed, and cannot show that tea is the reason. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 13 |
| Healthy Aging | Biological association | Very low certainty | Dementia and memory loss risk (green tea research): These results are for green tea, not genmaicha. Observational studies lean towards lower risk in green tea drinkers, but they are few and mixed, and cannot show that tea is the reason. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 13 |
| Blood Sugar Balance | Evidence against | Blood sugar in type 2 diabetes (green tea research): These results are for green tea, not genmaicha. A meta-analysis of 14 trials found no significant effect of green tea supplements on blood sugar measures in people with type 2 diabetes. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 3 | |
| Metabolic Health | Evidence against | Blood sugar in type 2 diabetes (green tea research): These results are for green tea, not genmaicha. A meta-analysis of 14 trials found no significant effect of green tea supplements on blood sugar measures in people with type 2 diabetes. Genmaicha is only partly tea leaf, so what this means for a cup of genmaicha is not known. | 3 |
B. Body systems
| Connected to | Kind of connection | Evidence status | Context | Studies |
|---|---|---|---|---|
| Cardiovascular System | Biological association | Not enough evidence | Studied for: Genmaicha itself (green tea with roasted rice) Studied for: Cholesterol (green tea research) | 14 25 6 10 28 20 1 |
| Metabolism Weight | Biological association | Low certainty | Studied for: Body weight (green tea research) Studied for: Blood sugar in type 2 diabetes (green tea research) | 12 28 3 |
| Cellular | Biological association | Not enough evidence | Studied for: Cancer risk (green tea research) | 5 28 |
| Brain Focus | Biological association | Low certainty | Studied for: Attention, memory and mood (green tea research) Studied for: Dementia and memory loss risk (green tea research) | 15 13 |
C. Body parts and organs
E. Health conditions
| Connected to | Kind of connection | Evidence status | Context | Studies |
|---|---|---|---|---|
| Pregnancy | Contraindication | Low certainty | Counts toward the caffeine limit. Preparation or compound: Green tea (caffeine) |
29 28 |
| Iron-deficiency anemia | Adverse effect or risk | Very low certainty | Tea can lower iron absorption; one case report. Preparation or compound: Green tea drink |
9 7 |
| Acrylamide from roasted food | Adverse effect or risk | Not enough evidence | Roasting forms acrylamide; EFSA links dietary acrylamide to possible cancer risk. No figure for a cup of genmaicha. Preparation or compound: Roasted rice and roasted tea (not measured in genmaicha) |
30 22 14 |
I. Biomarkers
| Connected to | Kind of connection | Evidence status | Context | Studies |
|---|---|---|---|---|
| LDL cholesterol | Biological association | Low certainty | Measured in trials: lowered. A lab change is not the same as a health benefit. | 25 10 6 |
| Systolic blood pressure | Biological association | Low certainty | Measured in trials: lowered. A lab change is not the same as a health benefit. | 20 10 6 |
| Body weight | Biological association | Low certainty | Measured in trials: unchanged. A lab change is not the same as a health benefit. | 12 |
| Death from any cause | Biological association | Low certainty | Measured in trials: lowered. A lab change is not the same as a health benefit. | 1 |
| HbA1c | Biological association | Evidence against | Measured in trials: unchanged. A lab change is not the same as a health benefit. | 3 |
| Attention and memory tests | Biological association | Low certainty | Measured in trials: raised. A lab change is not the same as a health benefit. | 15 |
J. Genes, receptors and enzymes
L. Active compounds
| Connected to | Kind of connection | Evidence status | Context | Studies |
|---|---|---|---|---|
| Caffeine | Adverse effect or risk | Moderate certainty | Counts toward daily caffeine; see FDA and NHS figures. Preparation or compound: Green tea |
27 29 |
| Epigallocatechin gallate (EGCG) | Biological association | Human | Liver effects at high supplement doses; other actions not established in the sources read. Preparation or compound: Leaf |
32 4 |
| Caffeine | Biological association | Human | Stimulant; see Safety tab. Preparation or compound: Leaf |
33 27 |
| L-theanine | Biological association | Human | Reviewers link benefits for attention to caffeine and L-theanine together. Preparation or compound: Leaf |
34 15 16 |
| Tannins and other polyphenols | Biological association | Human | Tea polyphenols lower iron absorption (radio-iron study, black and herb teas). Preparation or compound: Leaf and stem |
16 9 |
| Acrylamide | Biological association | Food analysis and regulator | EFSA: dietary acrylamide potentially increases cancer risk. Preparation or compound: Roasted grain and roasted tea |
30 22 18 24 14 |
| Rice starch, sugars, amino acids and phenolics (after roasting) | Biological association | Food analysis | Aroma and colour; no health effect shown. Preparation or compound: Roasted rice grain |
14 |
Each connection is stored with the ingredient, the connected record, the kind of connection, the evidence status, the supporting studies, the preparation or compound involved, and a review date (last reviewed October 25, 2026).
The evidence
The research centre for Genmaicha (Green Tea with Roasted Rice). Every record here was checked against PubMed or the publisher's page; we never list a study we have not verified.
Evidence by outcome
Bars show how many studies we found for each outcome, not how well it works. People are added up across trials only (reviews are not added, to avoid double counting).
How we rate evidence
High certainty
Several well-run trials or reviews agree; further research is unlikely to change the picture much.
Moderate certainty
Good trials point the same way, but some doubt remains.
Low certainty
Small, short or inconsistent trials. The finding could change with better research.
Very low certainty
Very little or very weak human data. Treat as a possibility only.
Mixed findings
Trials or reviews disagree with each other.
Not enough evidence
Not enough human research to say either way.
Evidence against
Good research found no benefit, or found harm.
We take the reviewers' own risk-of-bias and GRADE statements where they exist, and otherwise judge from study size, design, consistency, directness and whether a product matches what is sold. Many publications do not make evidence high. Method note: We built this page from our green tea profile, whose PubMed abstracts were read on 2026-10-25, and searched PubMed for genmaicha and roasted rice tea. We found no clinical study of either, and four food-chemistry papers on acrylamide and roasted grain (abstracts read). The NCCIH and EFSA acrylamide pages were read in full; LiverTox and LactMed were read only as PubMed summary records. Plant names were checked in GBIF. Certainty ratings are the compiler's own reading. No funding statement was read for most papers, so industry links are not ruled out.
Study library: every study we checked 36
| Study | Design | People | Product, dose, length | Result |
|---|---|---|---|---|
| Abe 2019 Green tea consumption and mortality in Japanese men and women: a pooled analysis of eight population-based cohort studies in Japan European Journal of Epidemiology · PMID 31392470 · DOI |
Pooled cohort |
313381 313,381 Japanese adults in eight cohorts; 52,943 deaths over a mean 17.3 years |
Green tea drinking (self-reported) leaf (drink) Five or more cups a day versus less than one Mean follow-up 17.3 years · vs Drinking less than 1 cup a day |
Five or more cups a day versus less than one: all-cause death HR 0.90 (95% CI 0.87 to 0.94) in men and 0.82 (0.74 to 0.90) in women; heart disease HR 0.82 (0.75 to 0.90) men, 0.75 (0.68 to 0.84) women; stroke-type (cerebrovascular) HR 0.76 (0.68 to 0.85) men, 0.78 (0.68 to 0.89) women. In women, total cancer death HR 0.89 (0.83 to 0.96) at 1 to 2 cups and 0.91 (0.85 to 0.98) at 3 to 4 cups. Lower death rates among heavy green tea drinkers (an association) (All-cause HR 0.90 (0.87, 0.94) men; 0.82 (0.74, 0.90) women) Methods, limits and fundingOutcomes: Deaths from all causes, heart disease, stroke, cancer, respiratory disease Limitations: Observational: tea drinkers may differ in diet, exercise and health; Japanese data may not apply elsewhere Funding and conflicts: Not stated in the abstract Read: abstract |
| Acosta 2023 Hepatotoxicity with High-Dose Green Tea Extract: Effect of Catechol-O-Methyltransferase and Uridine 5-Diphospho-glucuronosyltransferase 1A4 Genotypes Journal of Dietary Supplements · PMID 36178169 · DOI |
Controlled trial |
1075 Postmenopausal women in the Minnesota Green Tea Trial (400 in the extract group), mean age 59.8 years |
High-dose green tea extract capsules (843 mg/day EGCG) versus placebo capsules extract 843 mg/day EGCG 12 months · vs Placebo capsules |
This is a secondary analysis. In the extract group, women with the UGT1A4 (rs6755571) A/C variant had larger rises in ALT (about +78% and +82% at months 6 and 9) than women with C/C (about +28% and +30%). The authors suggest this variant may be a risk factor for meaningful liver enzyme rises with 6 to 9 months of high-dose extract. Genes may affect who gets liver enzyme rises on high-dose extract (ALT change differences p<0.001 and p=0.004 (months 6 and 9)) Methods, limits and fundingOutcomes: Liver enzymes by gene variant Limitations: Secondary analysis; mostly white women; extract only; not about tea Funding and conflicts: Not stated in the abstract Read: abstract |
| Asbaghi 2021 Effect of green tea on glycemic control in patients with type 2 diabetes mellitus: A systematic review and meta-analysis Diabetes & Metabolic Syndrome · PMID 33285391 · DOI |
Meta-analysis |
14 randomised trials in people with type 2 diabetes | Green tea supplementary intake Differed Differed · vs Control |
Supplementary green tea had no significant effect on fasting glucose, fasting insulin, HbA1c or HOMA-IR. No significant effect found Methods, limits and fundingOutcomes: Fasting glucose, fasting insulin, HbA1c, HOMA-IR Limitations: Small trials; the abstract does not say whether the trials used drink or extract; no effect found is not proof of no effect Funding and conflicts: Not stated in the abstract Read: abstract |
| EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) 2018 Scientific opinion on the safety of green tea catechins EFSA Journal · PMID 32625874 · DOI |
Regulatory opinion |
Review of published studies, authority reports and submitted data | Green tea infusions, reconstituted drinks and food supplements containing catechins leaf (drink) and extract Mean EGCG intake from infusions in the EU 90 to 300 mg/day (up to 866 mg/day for high-level drinkers); supplements 5 to 1,000 mg/day |
Catechins from traditionally prepared green tea infusions, and reconstituted drinks of the same composition, are in general considered safe at the intakes reported in EU countries. Rare cases of liver injury have been reported after infusions, most probably an idiosyncratic (individual) reaction. Clinical trials show that EGCG at or above 800 mg a day taken as a food supplement raised liver enzymes (serum transaminases) compared with control. Drink generally safe at usual intakes; high-dose supplements raise liver enzymes Methods, limits and fundingOutcomes: Liver safety of catechins (EGCG) Limitations: Abstract only was read; the full opinion could not be opened Funding and conflicts: Regulator opinion Read: abstract |
| Filippini 2020 Green tea (Camellia sinensis) for the prevention of cancer Cochrane Database of Systematic Reviews · PMID 32118296 · DOI |
Systematic review |
142 studies: 11 randomised trials (1795 people, green tea extract versus placebo) and 131 observational studies (over 1,100,000 people) | Green tea extract in trials; drinking green tea in observational studies leaf (drink) and extract Differed Differed · vs Placebo (trials); lowest intake (cohorts) |
Trials of extract (low-certainty): prostate cancer RR 0.50 (95% CI 0.18 to 1.36), gynaecological cancer RR 1.50 (0.41 to 5.48), non-melanoma skin cancer RR 1.00 (0.06 to 15.92). Observational, highest versus lowest intake: overall cancer incidence RR 0.83 (0.65 to 1.07, three studies); cancer death RR 0.99 (0.91 to 1.07, eight studies); both low-certainty. Results conflicted by study design for oesophageal, prostate and urinary cancers and leukaemia. The authors call the evidence limited and inconsistent. Extract side effects included stomach and gut problems, raised liver enzymes and, more rarely, insomnia, raised blood pressure and skin reactions. No clear effect on cancer risk; inconsistent (Prostate RR 0.50 (0.18, 1.36); cancer incidence RR 0.83 (0.65, 1.07); cancer mortality RR 0.99 (0.91, 1.07)) Methods, limits and fundingOutcomes: Cancer incidence and death, adverse effects, quality of life Limitations: Most studies in Asian populations who drink a lot of green tea; observational studies cannot prove cause; trials used extract Funding and conflicts: Non-US government support listed in PubMed record Read: abstract |
| Hartley 2013 Green and black tea for the primary prevention of cardiovascular disease Cochrane Database of Systematic Reviews · PMID 23780706 · DOI |
Systematic review |
821 11 randomised trials of at least 3 months in healthy adults or adults at high risk of heart disease; 7 trials tested green tea, 4 black tea |
Green tea, black tea or tea extracts (doses and forms differed between trials) leaf (drink) and extracts Differed between trials At least 3 months · vs No intervention, placebo or minimal intervention |
No trial reported heart or blood vessel events. Green tea: total cholesterol -0.62 mmol/L (95% CI -0.77 to -0.46), LDL cholesterol -0.64 mmol/L (-0.77 to -0.52), systolic blood pressure -3.18 mmHg (-5.25 to -1.11), diastolic -3.42 (-4.54 to -2.30). The authors say only a small number of studies contributed and the green tea results were not stable to sensitivity analysis. Adverse events in five trials were judged unlikely to be due to the tea. Small lowering of cholesterol and blood pressure, unstable (TC MD -0.62 (-0.77, -0.46); LDL MD -0.64 (-0.77, -0.52); SBP MD -3.18 (-5.25, -1.11)) Methods, limits and fundingOutcomes: Heart disease events, blood pressure, cholesterol Limitations: Few trials per analysis, risk of bias, forms and doses mixed (drink and extract); no long-term follow-up Funding and conflicts: Non-US government support listed in PubMed record; no industry funding stated in the abstract Read: abstract |
| He 2024 Severe iron-deficiency anemia after short-term moderate consumption of green tea in woman: A rare case report Heliyon · PMID 39263133 · DOI |
Case report |
1 One woman who drank moderate amounts of green tea for about three months |
Green tea drink leaf (drink) Moderate (amount not given in the abstract) About 3 months |
Haemoglobin fell by 6.9 g/dl with severe iron-deficiency anemia. After she changed her tea habits there was no recurrence. The authors say clinicians should know even moderate tea intake can cause severe anemia in people who are especially vulnerable to its effect on iron absorption. One reported case of severe anemia Methods, limits and fundingOutcomes: Haemoglobin Limitations: Single case; other causes of iron loss are not described in the abstract Funding and conflicts: Not stated Read: abstract |
| Hu 2018 The safety of green tea and green tea extract consumption in adults - Results of a systematic review Regulatory Toxicology and Pharmacology · PMID 29580974 · DOI |
Systematic review |
Toxicology studies and adverse-event data from 159 human intervention studies | Brewed green tea, green tea in drinks or food, and concentrated catechin-rich preparations leaf (drink) and extract |
Liver was the target organ. Liver adverse events in humans came from a limited range of concentrated, catechin-rich preparations taken as large single doses, and not from brewed tea or extracts used in drinks or food. The authors derived a safe intake level for adults for solid single-dose preparations and a separate, higher observed safe level for beverage forms (the numbers are in the paper). Liver effects tied to concentrated bolus-dose preparations, not brewed tea Methods, limits and fundingOutcomes: Liver adverse events Limitations: Abstract only was read; the abstract does not state who funded the review Funding and conflicts: Funding and conflict-of-interest statement not read Read: abstract |
| Hurrell 1999 Inhibition of non-haem iron absorption in man by polyphenolic-containing beverages British Journal of Nutrition · PMID 10999016 |
Controlled trial |
Adult volunteers given a bread meal with radio-labelled iron | Black tea, herb teas (chamomile, vervain, lime flower, pennyroyal, peppermint), coffee and cocoa leaf (drink) Test beverages with different polyphenol amounts Single meals · vs Water control meal |
All the beverages reduced iron absorption in a way that depended on their polyphenol content. Black tea cut absorption by 79 to 94 percent, peppermint tea 84, pennyroyal 73, cocoa 71, vervain 59, lime flower 52 and camomile 47 percent. Milk made little difference. Green tea was NOT tested. Large drop in iron absorption from a meal Methods, limits and fundingOutcomes: Iron absorption from the meal Limitations: Green tea not tested; single meals in adults; applying this to green tea is an inference Funding and conflicts: Non-US government support listed in PubMed record Read: abstract |
| Igho-Osagie 2020 Short-Term Tea Consumption Is Not Associated with a Reduction in Blood Lipids or Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Journal of Nutrition · PMID 33188386 · DOI |
Meta-analysis |
798 14 randomised trials in healthy adults and at-risk adults (obesity, prediabetes, borderline high cholesterol, metabolic syndrome) |
Green tea or black tea leaf (drink) Differed 4 to 24 weeks (mean 7.4) · vs Placebo or control |
No significant effect of tea on systolic or diastolic blood pressure, total, LDL or HDL cholesterol or triglycerides. Strength of evidence was low to moderate because the studies were small and underpowered. No significant effect in short trials (No significant effects (intervals not given in the abstract)) Methods, limits and fundingOutcomes: Blood pressure, total, LDL and HDL cholesterol, triglycerides Limitations: Small trials, short duration, green and black tea pooled; absence of effect is not proof of no effect Funding and conflicts: Non-US government support listed in PubMed record Read: abstract |
| Jayasingha 2025 Fluoride in tea: accumulation, dietary exposure, and future strategies for risk mitigation in food safety; a scoping review Critical Reviews in Food Science and Nutrition · PMID 40504749 · DOI |
Scoping review lab/food analysis |
88 studies worldwide on fluoride in tea | Tea (all types) leaf (drink) |
Tea plants take up fluoride from soil. Longer brewing released more fluoride. Average levels by type were brick tea 4.78 mg/L, black tea 2.73, green tea 1.37, white tea 0.49 and herbal tea 0.17. The review says black tea poses risks for children and for adults in high-intake regions; excessive intake may cause tooth and bone fluorosis and kidney disease. Green tea has less fluoride than black or brick tea but more than white or herbal tea Methods, limits and fundingOutcomes: Fluoride in brewed tea Limitations: Scoping review; averages mix many countries; local water also adds fluoride Funding and conflicts: Not stated Read: abstract |
| Jurgens 2012 Green tea for weight loss and weight maintenance in overweight or obese adults Cochrane Database of Systematic Reviews · PMID 23235664 · DOI |
Systematic review |
Randomised trials of at least 12 weeks in overweight or obese adults; six trials outside Japan (532 people) and eight in Japan (1030 people) | Green tea preparations (drink and extracts) leaf (drink) and extracts Differed 12 to 13 weeks · vs Control |
Outside Japan: weight difference -0.04 kg (95% CI -0.5 to 0.4), BMI -0.2 kg/m2 (-0.5 to 0.1), waist -0.2 cm (-1.4 to 0.9). The eight Japanese trials were too different to pool; weight differences ranged from -0.2 to -3.5 kg. Adverse events in four of eight trials that recorded them were mild to moderate; two needing hospital care were reported as not related. Almost no weight change outside Japan; mixed results in Japanese trials (Weight MD -0.04 kg (-0.5, 0.4) outside Japan) Methods, limits and fundingOutcomes: Weight, BMI, waist circumference, adverse events Limitations: Short trials; green tea preparations of many kinds; not a drink-only result Funding and conflicts: Non-US government support listed in PubMed record Read: abstract |
| Kakutani 2019 Green Tea Intake and Risks for Dementia, Alzheimer's Disease, Mild Cognitive Impairment, and Cognitive Impairment: A Systematic Review Nutrients · PMID 31137655 · DOI |
Systematic review |
3 cohort studies and 5 cross-sectional studies | Green tea drinking leaf (drink) · vs Lower or no intake |
One cohort and three cross-sectional studies supported a benefit, one cohort and one cross-sectional partly supported it, and one cohort and one cross-sectional found no association. The authors say well-designed cohort studies are needed. Mixed observational results Methods, limits and fundingOutcomes: Dementia, Alzheimer disease, mild cognitive impairment, cognitive impairment Limitations: Observational only; small number of studies; cannot show cause Funding and conflicts: Not stated in the abstract Read: abstract |
| Kim 2021 Effects of germination and roasting on physicochemical and sensory characteristics of brown rice for tea infusion. Food Chemistry · PMID 33618097 · DOI |
Food analysis food |
Brown rice, germinated or not, roasted to make a rice tea (lab study) | Brown rice (Oryza sativa) roasted grain |
Roasting produced volatile compounds and phenolics. Acrylamide in roasted germinated brown rice was significantly lower than in roasted ungerminated brown rice because it had less asparagine. Germination raised free amino acids, reducing sugars and phenolics. Roasted brown rice for tea contains acrylamide; germinating first lowered it Methods, limits and fundingOutcomes: Sugars, amino acids, phenolics, acrylamide, sensory quality Limitations: Lab food study; no acrylamide figures in the abstract; not a trial in people; one company author affiliation. Funding and conflicts: One author lists a food company affiliation (Food Research Institute, Dongsuh Companies Inc.) Read: abstract |
| Mancini 2017 Green tea effects on cognition, mood and human brain function: A systematic review Phytomedicine · PMID 28899506 · DOI |
Systematic review |
21 studies: 4 randomised trials, 12 crossover studies, 4 cross-sectional studies and 1 cohort | Green tea, green tea extract, L-theanine or EGCG leaf (drink), extract and isolated compounds Differed Differed · vs Differed |
The reviewers found evidence that green tea influences psychological symptoms (for example less anxiety), cognition (for example memory and attention) and brain function (for example working-memory activation on brain scans). Benefits on cognition were seen with caffeine and L-theanine together, with less effect from either alone, so the effect cannot be put down to one ingredient. Possible small effects on attention and memory Methods, limits and fundingOutcomes: Anxiety and mood, memory and attention, brain activity Limitations: Mixes drink, extract and isolated compounds; many short or single-dose studies; PubMed only; quality scores are the reviewers own Funding and conflicts: Not stated in the abstract Read: abstract |
| NICHD / 2006 Drugs and Lactation Database (LactMed): Green Tea LactMed (NCBI Bookshelf) · PMID 30000907 |
Database record |
n/a | Green tea leaves and stems leaf and stem |
Green tea leaves and stems contain caffeine, L-theanine, polyphenols and tannins. Fussiness, jitteriness and poor sleep have been reported in infants of mothers with extremely high caffeine intakes. Giving tea directly to infants can interfere with iron absorption and cause anemia, but anemia in breastfed infants has not been reported with maternal tea intake. Passage of L-theanine into breastmilk has not been studied. No studies of oral green tea extract in breastfeeding were found. No clear harm from usual maternal tea intake; caution at very high caffeine Methods, limits and fundingOutcomes: Breastfeeding safety Limitations: Summary record; no new data Funding and conflicts: Public database Read: abstract |
| NIDDK 2012 LiverTox: Green Tea (Clinical and Research Information on Drug-Induced Liver Injury) LiverTox (NCBI Bookshelf) · PMID 31643260 |
Database record |
n/a | Green tea extract and, more rarely, large amounts of green tea leaf and extract |
Green tea extract and, more rarely, ingestion of large amounts of green tea have been implicated in cases of clinically apparent acute liver injury, including instances of acute liver failure and either need for urgent liver transplantation or death. Rare but serious liver injury, mostly with extract Methods, limits and fundingOutcomes: Drug-induced liver injury Limitations: Only the PubMed summary was read; the full LiverTox page was not opened Funding and conflicts: Public database Read: abstract |
| Ono 2003 Analysis of acrylamide by LC-MS/MS and GC-MS in processed Japanese foods. Food Additives and Contaminants · PMID 12623644 · DOI |
Food analysis food |
63 63 processed Japanese food samples covering 31 product types |
Processed foods roasted barley grains for mugi-cha tea; rice crackers |
Roasted barley grains for mugi-cha tea contained 200 to 600 micrograms per kg of acrylamide. Rice crackers processed by grilling or frying were lower than potato crisps. The authors say acrylamide formation is strongly influenced by processing conditions. Acrylamide in roasted barley tea grain 200 to 600 micrograms per kg Methods, limits and fundingOutcomes: Acrylamide level in foods Limitations: Roasted barley, not rice; dry grain, not a brewed drink. Funding and conflicts: Government institute; no industry funding stated in the abstract Read: abstract |
| Pillukat 2014 Concentrated green tea extract induces severe acute hepatitis in a 63-year-old woman - a case report with pharmaceutical analysis Journal of Ethnopharmacology · PMID 24862489 · DOI |
Case report |
1 A 63-year-old woman taking green tea capsules on the advice of a cancer support group |
Concentrated green tea extract capsules (EGCG 93.2% of the catechins found) extract Very high EGCG dose level per the analysis |
Severe hepatitis assessed as probably caused by the capsules (CIOMS/RUCAM score). The liver tissue pattern fit drug-induced hepatitis and other causes were excluded. After stopping, and a treatment called albumin dialysis, she recovered quickly and fully. Lab analysis of the capsules found no contaminants. Severe but reversible liver injury linked to concentrated extract Methods, limits and fundingOutcomes: Liver injury Limitations: Single case; extract, not brewed tea Funding and conflicts: Not stated Read: abstract |
| Rezaei 2025 Effect of green tea supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomised controlled trials Blood Pressure · PMID 40497293 · DOI |
Meta-analysis |
36 randomised trials in adults | Green tea supplementation (forms not broken out in the abstract) Not given here Studies of 8 weeks or less showed stronger effects · vs Control or placebo |
Systolic blood pressure fell by 1.08 mmHg (95% CI -1.98 to -0.18; I2 85%) and diastolic by 1.09 mmHg (-1.67 to -0.50; I2 74%). Effects were stronger in people with raised starting blood pressure, shorter studies, Asian populations and women. No clear link between size of change and dose or duration. The authors call green tea a complementary approach, not a treatment. Very small average blood pressure drop with large differences between studies (SBP -1.08 (-1.98, -0.18); DBP -1.09 (-1.67, -0.50)) Methods, limits and fundingOutcomes: Systolic and diastolic blood pressure Limitations: Very high heterogeneity; the abstract does not separate drink from extract; the GRADE rating is not given in the abstract Funding and conflicts: Not stated in the abstract Read: abstract |
| Rodriguez 2020 Human exposure to fluoride from tea (Camellia sinensis) in a volcanic region - Canary Islands, Spain Environmental Science and Pollution Research · PMID 32740848 · DOI |
Food analysis lab/food analysis |
90 90 tea samples (Canary Islands) |
Mixed, black and other teas prepared with local tap water leaf (drink) Two 250 mL cups a day assumed |
Mixed teas (2.82 mg/L) and black teas (2.28 mg/L) had the highest fluoride. Two daily cups of those teas made with local tap water would give children aged 4 to 8 a large share (74.4% and 63.6%) of the EFSA upper intake level. The authors advise less tea for children and in pregnancy. Fluoride in tea can matter for young children in some regions Methods, limits and fundingOutcomes: Fluoride in tea Limitations: Local water and region; green tea results are not given in the abstract Funding and conflicts: Not stated Read: abstract |
| Takatsuki 2003 Determination of acrylamide in processed foods by LC/MS using column switching. Shokuhin Eiseigaku Zasshi · PMID 12846155 · DOI |
Food analysis food |
Processed and cooked foods bought in Japanese retail markets, including roasted barley tea (mugi-cha) and roasted green tea (hoji-cha) | Roasted foods dried roasted product (not a brewed drink) |
Roasted foods (roasted sesame seed, roasted barley mugi-cha, roasted tea hoji-cha, coffee beans, curry powder) contained 116 to 567 ng/g of acrylamide. Potato chips and French fries were higher (467 to 3,544 ng/g). Foods with much water tended to be lower than dry foods. Acrylamide found in roasted tea and roasted barley Methods, limits and fundingOutcomes: Acrylamide level in foods Limitations: Measured the dry roasted product, not a brewed cup; roasted rice or genmaicha were not named in the abstract. Funding and conflicts: Government institute method paper; no industry funding stated in the abstract Read: abstract |
| Taylor 1999 Probable antagonism of warfarin by green tea Annals of Pharmacotherapy · PMID 10332534 · DOI |
Case report |
1 A 44-year-old man with a mechanical aortic heart valve taking warfarin |
Green tea drink leaf (drink) Half a gallon to a gallon of green tea a day for about a week About 1 week before the low reading |
The INR fell from 3.79 to 1.37 about three weeks later, and was 1.14 a month after. He had started drinking one-half to one gallon of green tea a day about a week before the INR of 1.37. After stopping the tea the INR rose to 2.55. The authors suggested vitamin K in the tea. A drop in warfarin effect linked in time to a very large amount of green tea (INR 3.79 to 1.37) Methods, limits and fundingOutcomes: Blood clotting test (INR) Limitations: One case; cannot prove cause; very large amount of tea; vitamin K content was not measured Funding and conflicts: Not stated Read: abstract |
| Yoshida 2005 Acrylamide in Japanese processed foods and factors affecting acrylamide level in potato chips and tea. Advances in Experimental Medicine and Biology · PMID 16438315 · DOI |
Food analysis food |
Processed foods sold in Japanese markets; roasted green tea | Processed foods, roasted green tea roasted green tea leaf |
Rice crackers and candied sweet potatoes were under 350 micrograms per kg. The abstract says roasting time and temperature affect acrylamide in roasted green tea, but gives no figures. Roasting time and temperature change acrylamide in roasted green tea Methods, limits and fundingOutcomes: Acrylamide level and what changes it Limitations: Abstract gives no tea figures; not about genmaicha or roasted rice. Funding and conflicts: Government institute; no industry funding stated in the abstract Read: abstract |
| Zheng 2011 Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials American Journal of Clinical Nutrition · PMID 21715508 · DOI |
Meta-analysis |
1136 14 randomised trials in adults |
Green tea beverage or green tea extract leaf (drink) and extract Differed Differed · vs Control |
Total cholesterol lowered by 7.20 mg/dL (95% CI -8.19 to -6.21) and LDL cholesterol by 2.19 mg/dL (-3.16 to -1.21); HDL cholesterol did not change significantly. The authors say changes were not influenced by type of intervention, dose, duration, health status or study quality. Small average drop in total and LDL cholesterol (TC -7.20 (-8.19, -6.21) mg/dL; LDL -2.19 (-3.16, -1.21) mg/dL) Methods, limits and fundingOutcomes: Total, LDL and HDL cholesterol Limitations: Mixes drinks and extracts; the abstract gives no separate drink-only result; later reviews found no effect in short trials (see Igho-Osagie 2020) Funding and conflicts: Non-US government support listed in PubMed record; funding details not in the abstract Read: abstract |
| n/a 2016 IARC (WHO): Press release no. 244, coffee, mate and very hot beverages (15 June 2016) n/a · Source |
Authoritative guidance n/a |
n/a | n/a |
IARC classified drinking very hot beverages as probably carcinogenic to humans (Group 2A), based on limited evidence from studies in places where tea or mate is drunk very hot, and said it is the temperature rather than the drink that appears responsible. Methods, limits and fundingOutcomes: IARC classified drinking very hot beverages as probably carcinogenic to humans (Group 2A), based on limited evidence from studies in places where tea or mate is drunk very hot, and said it is the temperature rather than the drink that appears responsible. Limitations: Press release read from the PDF on 2026-10-25; the exact temperature figure could not be read from the extracted text, so it is not quoted here. Read: full-text |
| n/a 2024 FDA: Spilling the Beans: How Much Caffeine Is Too Much? (content current as of 28 Aug 2024) n/a · Source |
Authoritative guidance n/a |
n/a | n/a |
Lists green tea at 37 mg caffeine per 12 fl oz drink. Cites 400 mg a day as an amount not generally linked with negative effects in most adults, with wide differences in sensitivity. Lists signs of too much caffeine (faster heart rate, palpitations, high blood pressure, insomnia, anxiety, jitters, upset stomach, nausea, headache). Says caffeinated drinks should be avoided for children younger than age 2 (quoting the Dietary Guidelines) and that pregnant or breastfeeding people should talk to a health professional. Methods, limits and fundingOutcomes: Lists green tea at 37 mg caffeine per 12 fl oz drink. Cites 400 mg a day as an amount not generally linked with negative effects in most adults, with wide differences in sensitivity. Lists signs of too much caffeine (faster heart rate, palpitations, high blood pressure, insomnia, anxiety, jitters, upset stomach, nausea, headache). Says caffeinated drinks should be avoided for children younger than age 2 (quoting the Dietary Guidelines) and that pregnant or breastfeeding people should talk to a health professional. Limitations: Consumer guidance page, not a trial. Read in full on 2026-10-25. Read: full-text |
| n/a 2025 NCCIH (NIH): Green Tea: Usefulness and Safety (last updated February 2025) n/a · Source |
Authoritative guidance n/a |
n/a | n/a |
Says definite conclusions cannot yet be reached on whether green tea helps for most uses. Cancer results inconsistent; lower heart disease risk seen in Asian but not Western groups; small cholesterol drops mostly from extract trials; no safety concerns reported for green tea as a drink in adults; liver injury uncommon and mostly with extract tablets or capsules; interactions with nadolol (high-dose green tea), atorvastatin (extract) and raloxifene; keep caffeine moderate in pregnancy. Methods, limits and fundingOutcomes: Says definite conclusions cannot yet be reached on whether green tea helps for most uses. Cancer results inconsistent; lower heart disease risk seen in Asian but not Western groups; small cholesterol drops mostly from extract trials; no safety concerns reported for green tea as a drink in adults; liver injury uncommon and mostly with extract tablets or capsules; interactions with nadolol (high-dose green tea), atorvastatin (extract) and raloxifene; keep caffeine moderate in pregnancy. Limitations: A regulator-style fact sheet, not a trial. Page text read in full on 2026-10-25. Read: full-text |
| n/a 2026 NHS (UK): Foods to avoid in pregnancy (page last reviewed 15 June 2026) n/a · Source |
Authoritative guidance n/a |
n/a | n/a |
Says you should not have more than 200 mg of caffeine a day in pregnancy, estimates about 75 mg in a cup of tea such as black or green tea, and says too much caffeine has been linked to a higher chance of miscarriage and stillbirth. Methods, limits and fundingOutcomes: Says you should not have more than 200 mg of caffeine a day in pregnancy, estimates about 75 mg in a cup of tea such as black or green tea, and says too much caffeine has been linked to a higher chance of miscarriage and stillbirth. Limitations: Public-health guidance, not a trial. Read in full on 2026-10-25. The per-cup figure is an estimate. Read: full-text |
| n/a 2026 EFSA: Acrylamide topic page (read 2026-10-25) n/a · Source |
Authoritative guidance n/a |
n/a | n/a |
Acrylamide forms naturally in starchy foods during high-temperature cooking, including roasting, through the Maillard reaction (sugars with the amino acid asparagine). EFSA found it in potato crisps, French fries, bread, biscuits and coffee. In 2015 EFSA published its first full risk assessment, and experts concluded that acrylamide in food potentially increases the risk of developing cancer for consumers in all age groups. Methods, limits and fundingOutcomes: Acrylamide forms naturally in starchy foods during high-temperature cooking, including roasting, through the Maillard reaction (sugars with the amino acid asparagine). EFSA found it in potato crisps, French fries, bread, biscuits and coffee. In 2015 EFSA published its first full risk assessment, and experts concluded that acrylamide in food potentially increases the risk of developing cancer for consumers in all age groups. Limitations: Regulator web page, read in full on 2026-10-25. It does not name tea or rice. Read: full-text |
| n/a 2026 EMA: Camelliae sinensis non fermentatum folium (green tea), herbal medicinal product page n/a · Source |
Authoritative guidance n/a |
n/a | n/a |
Page lists Camellia sinensis (L.) Kuntze, non fermentatum folium (green tea), therapeutic area "Fatigue and weakness", status "Assessment finalised", outcome "European Union herbal monograph". Documents: final EU herbal monograph (EMA/HMPC/283630/2012, published 29 April 2014), assessment report and an addendum to the assessment report (EMA/HMPC/30571/2022, published 26 September 2022). Methods, limits and fundingOutcomes: Page lists Camellia sinensis (L.) Kuntze, non fermentatum folium (green tea), therapeutic area "Fatigue and weakness", status "Assessment finalised", outcome "European Union herbal monograph". Documents: final EU herbal monograph (EMA/HMPC/283630/2012, published 29 April 2014), assessment report and an addendum to the assessment report (EMA/HMPC/30571/2022, published 26 September 2022). Limitations: Only the web page was read. The monograph and assessment-report PDFs were not opened, so the wording of the monograph is NOT verified. Read: abstract |
| n/a 2026 PubChem: epigallocatechin gallate (CID 65064), formula C22H18O11 n/a · Source |
Database record n/a |
n/a | n/a |
Compound record confirmed through the PubChem API on 2026-10-25. Methods, limits and fundingOutcomes: Compound record confirmed through the PubChem API on 2026-10-25. Limitations: Database record only. Read: full-text |
| n/a 2026 PubChem: caffeine (CID 2519), formula C8H10N4O2 n/a · Source |
Database record n/a |
n/a | n/a |
Compound record confirmed through the PubChem API on 2026-10-25. Methods, limits and fundingOutcomes: Compound record confirmed through the PubChem API on 2026-10-25. Limitations: Database record only. Read: full-text |
| n/a 2026 PubChem: L-theanine (CID 439378), formula C7H14N2O3 n/a · Source |
Database record n/a |
n/a | n/a |
Compound record confirmed through the PubChem API on 2026-10-25. Methods, limits and fundingOutcomes: Compound record confirmed through the PubChem API on 2026-10-25. Limitations: Database record only. Read: full-text |
| n/a 2026 GBIF Backbone Taxonomy: Camellia sinensis (L.) Kuntze (usage key 3189635), retrieved 2026-10-25 n/a · Source |
Database record n/a |
n/a | n/a |
Accepted species, family Theaceae, order Ericales, genus Camellia. Synonyms listed by the API include Camellia bohea (L.) Sweet, Camellia chinensis (Sims) Kuntze and Camellia cantonensis Lour. Methods, limits and fundingOutcomes: Accepted species, family Theaceae, order Ericales, genus Camellia. Synonyms listed by the API include Camellia bohea (L.) Sweet, Camellia chinensis (Sims) Kuntze and Camellia cantonensis Lour. Limitations: Taxonomic database record via the GBIF API. Read: full-text |
| n/a 2026 GBIF Backbone Taxonomy: Oryza sativa L. (usage key 2703459), retrieved 2026-10-25 n/a · Source |
Database record n/a |
n/a | n/a |
GBIF accepts Oryza sativa L., family Poaceae (the grass family), as the species name for cultivated rice. Methods, limits and fundingOutcomes: GBIF accepts Oryza sativa L., family Poaceae (the grass family), as the species name for cultivated rice. Limitations: Taxonomy lookup only; says nothing about the tea. Read: full-text |
What we do not know yet
- No trial or human study of genmaicha, or of roasted rice tea, was found.
- No measurement of caffeine, catechins or acrylamide in genmaicha or in a brewed cup was found.
- Acrylamide figures read are for dry roasted barley and roasted green tea, not roasted rice.
- Green tea trials mostly mix drinks and extracts, so results cannot be assigned to a cup of tea.
- Most population data come from Japan and China; results may not apply elsewhere.
- No measured lead, cadmium, arsenic, aluminium or pesticide values were found; the EMA monograph and LiverTox full text were not opened.
- No source on the history of the blend was read.
How new research is added
New studies are found by a saved PubMed search and are placed in a review queue. A person reads each one before it changes any evidence rating or safety wording. New publications never change ratings automatically.
Lab markers
What changed in blood or saliva tests during trials. A changed number is not the same as feeling or being healthier, and we give no "normal ranges".
Metabolic 3
LDL cholesterol
Lowered in trials
The cholesterol carried in the blood that is linked with higher heart disease risk.
Low certaintyResults and what it means
Why it was measured
To see whether green tea changes blood fats.
Statistical vs. clinical meaning
Small and inconsistent; a lab number, not a heart outcome.
Safety implication
None from the numbers; see the Safety tab for extract risks.
Body weight
Unchanged in trials
Weight in kilograms.
Low certaintyResults and what it means
Why it was measured
To see whether green tea helps with weight loss.
Statistical vs. clinical meaning
No meaningful change outside Japan.
Safety implication
None.
| Study | Result | People | Product |
|---|---|---|---|
| 12 | -0.04 kg (95% CI -0.5 to 0.4) outside Japan; -0.2 to -3.5 kg in Japanese trials, not pooled | Overweight adults, 12 to 13 weeks | Green tea preparations |
HbA1c
Unchanged in trials
A blood test that shows average blood sugar over about three months.
Evidence againstResults and what it means
Other 3
Systolic blood pressure
Lowered in trials
The top number in a blood pressure reading.
Low certaintyResults and what it means
Why it was measured
To see whether green tea changes blood pressure.
Statistical vs. clinical meaning
Very small and varied.
Safety implication
None from the numbers.
Death from any cause
Lowered in trials
The risk of dying from any cause during follow-up.
Low certaintyResults and what it means
Why it was measured
To see whether heavy green tea drinkers live longer.
Statistical vs. clinical meaning
Observational association only.
Safety implication
None.
| Study | Result | People | Product |
|---|---|---|---|
| 1 | HR 0.90 (0.87 to 0.94) men; 0.82 (0.74 to 0.90) women, 5+ cups a day versus under 1 | 313,381 Japanese adults | Self-reported green tea drinking |
Attention and memory tests
Raised in trials
Scores on computer or paper tests of attention and working memory.
Low certaintyResults and what it means
Why it was measured
To see whether green tea affects thinking.
Statistical vs. clinical meaning
Possible small effect.
Safety implication
None.
| Study | Result | People | Product |
|---|---|---|---|
| 15 | Reviewers report better memory and attention with caffeine and L-theanine together; no numbers in the abstract | 21 mixed studies | Green tea, extract, L-theanine, EGCG |
Safety
What studies and official sources say about side effects, medicines and who should check first. Each point shows what kind of evidence it comes from.
Main points to know 8
- Caffeine comes from the tea part. Genmaicha is made with green tea leaf, so it contains caffeine. We found no measurement of caffeine in genmaicha, and the rice adds none. For green tea, the FDA says about 400 mg a day from all sources is not generally linked with harm in most adults, and that too much can cause fast heartbeat, poor sleep, anxiety, jitters, upset stomach and headache. Sensitivity differs a lot between people. Authoritative guidance 27
- Roasted rice and acrylamide. Roasting starchy grain makes acrylamide, a chemical that forms from sugars and the amino acid asparagine at high heat (EFSA). In 2015 EFSA concluded that acrylamide in food potentially increases cancer risk for consumers of all ages. Japanese food analyses found acrylamide in roasted barley tea grain and in roasted green tea, and a lab study found it in roasted brown rice for tea. We found no measurement in genmaicha itself or in a brewed cup, so how much reaches the drink is unknown. Food analysis 30 22 18 24 14
- Tea and a green tea extract capsule are not the same thing. NCCIH reports no safety concerns for green tea drunk as a beverage by adults, apart from its caffeine. Genmaicha is a drink, not an extract. Liver injury is uncommon but has been reported, mostly with concentrated extract in tablets or capsules. EFSA judged traditionally prepared green tea infusions generally safe at the intakes seen in Europe, and found that high-dose EGCG supplements raised liver enzymes in trials. Do not carry safety or benefit results from one form to the other. Authoritative guidance 28 4 8
- Rare liver injury, mostly with extract. LiverTox says green tea extract, and more rarely large amounts of green tea, have been linked to clinically apparent liver injury, including liver failure needing transplant or ending in death. EFSA noted rare cases after infusions too, probably an individual reaction. A case report describes severe hepatitis from concentrated extract capsules that cleared after stopping them. Anyone with liver disease, or who has had liver trouble from a supplement, should ask a clinician before any extract. Case report 17 4 19
- Pregnancy, breastfeeding and young children. The NHS says not to have more than 200 mg of caffeine a day in pregnancy. NCCIH says to keep caffeine moderate in pregnancy and to ask your provider. LactMed reports fussiness, jitteriness and poor sleep in infants only with extremely high maternal caffeine, and says tea given directly to infants can interfere with iron absorption and cause anemia. The FDA quotes the Dietary Guidelines that caffeinated drinks should be avoided for children younger than age 2. Authoritative guidance 29 28 16 27
- Iron. Polyphenols in tea cut iron absorption from a meal in a radio-iron study, but that study did not test green tea. A 2024 case report describes severe iron-deficiency anemia in a woman after about three months of moderate green tea. If you have low iron or anemia, ask a clinician about tea around meals. Human study 9 7
- Medicines. NCCIH says high doses of green tea lowered blood levels of the heart medicine nadolol, green tea extract lowered levels of atorvastatin, and an NCCIH-funded study showed an interaction with raloxifene. One 1999 case report links very large amounts of green tea with weaker warfarin effect. Ask your pharmacist if you take any regular medicine. Authoritative guidance 28 23
- Very hot drinks. IARC classed drinking very hot beverages as probably carcinogenic to humans (Group 2A) for oesophageal cancer and said it is the temperature, not the drink, that appears responsible. This applies to hot tea as to any other very hot drink; letting a cup cool is a sensible step. Authoritative guidance 26
Side effects 7
| Effect | How often | Severity and recovery | Evidence |
|---|---|---|---|
| Caffeine effects (fast heartbeat, jitters, poor sleep, upset stomach) Listed by the FDA as signs of too much caffeine from any source. | Depends on how much caffeine you take and how sensitive you are; no rate in the sources read | mild to moderate Reversible when caffeine is cut back | Authoritative guidance 27 |
| Acrylamide intake from roasted grain A long-term, cancer-risk concern from food in general (EFSA), not a reaction you would notice after a cup. | No figure for genmaicha | not stated not applicable | Regulator statement 30 22 |
| Nausea, constipation, stomach discomfort and higher blood pressure (extract) NCCIH lists these for green tea extract supplements. | No rate in the sources read | mild Reversible after stopping (not stated) | Authoritative guidance 28 |
| Gut problems, raised liver enzymes, insomnia, raised blood pressure, skin reactions (extract) Cochrane lists these as adverse effects of green tea extract in trials. | Not given in the abstract | mild to moderate Not given | Systematic review 5 |
| Liver injury (mostly extract; rarely tea) High-dose extract raised liver enzymes in trials (EFSA, abstract). | Uncommon; no rate found | severe Mostly recovery after stopping; some cases need transplant or are fatal | Case report 28 17 19 4 |
| Lower iron absorption; anemia in a vulnerable person Green tea was not tested in the radio-iron study. | One case report | moderate to severe Improved after changing tea habits | Case report 9 7 |
| Fluoride intake from tea Green tea averaged 1.37 mg/L in a scoping review, below black and brick tea; the risk discussed is mainly for children and heavy drinkers. | Depends on tea type, brewing time and local water | not stated not stated | Food analysis 11 21 |
Liver
Liver injury linked to green tea is rare and mostly linked to concentrated extract capsules or tablets. LiverTox says extract, and more rarely very large amounts of tea, have been implicated in acute liver injury, including liver failure needing transplant or death. EFSA found raised liver enzymes with high-dose EGCG supplements in trials and noted rare liver injury after infusions, most probably an unusual individual reaction. A systematic review of 159 human studies found liver events came from concentrated, catechin-rich preparations taken in large single doses, not from brewed tea or extracts used in drinks or food. NCCIH says people with a specific immune-related gene variant seem especially susceptible, and a secondary analysis of a one-year extract trial found liver enzyme rises differed by gene variant. 17 4 8 19 2 28
How often. No rate in tea drinkers or extract users could be found in the sources read.
Monitoring. No monitoring advice was read from an agency. The Safety tab tells readers to stop extract and seek care if liver warning signs appear.
- p24862489.
This is a safety connection. It is not evidence that Genmaicha (Green Tea with Roasted Rice) supports liver health.
Medicines and supplements 6
| With | Why it matters | Importance | Evidence | What to do |
|---|---|---|---|---|
| Warfarin prescription | The case authors suggested vitamin K in the tea could counter warfarin; vitamin K was not measured. | One 1999 case report: INR fell from 3.79 to 1.37 after about a week of half a gallon to a gallon of green tea a day, and rose to 2.55 after stopping. It cannot prove cause and the amount was very large. | Case report Very low certainty 23 | Tell your prescriber about any big change in tea habits so your INR can be checked. |
| Nadolol (beta-blocker) prescription | Not described in the source read. | NCCIH says green tea at high doses reduced blood levels of nadolol and so its effectiveness. | Authoritative guidance Low certainty 28 | Ask your pharmacist if you take nadolol. |
| Atorvastatin (cholesterol medicine) prescription | Not described in the source read. | NCCIH says green tea extract can reduce blood levels of atorvastatin. This is about the extract. | Authoritative guidance Low certainty 28 | Ask your pharmacist before taking green tea extract with a statin. |
| Raloxifene (bone medicine) prescription | Not described in the source read. | NCCIH says a study it funded showed an interaction between green tea and raloxifene. Details were not given. | Authoritative guidance Low certainty 28 | Ask your pharmacist. |
| Iron supplements and iron-poor diets supplement | Tea polyphenols reduce iron absorption in general. | A radio-iron study showed black tea and herb teas cut iron absorption; green tea was not tested, and one case report links moderate green tea with severe anemia. | Human study Low certainty 9 7 | If you have low iron, ask a clinician about drinking tea away from meals. Whether that works was not tested in the sources read. |
| Other sources of caffeine food | Caffeine adds up across coffee, other teas, energy drinks and some supplements. | The FDA says its 400 mg figure is for all caffeine in a day. | Authoritative guidance Moderate certainty 27 29 | Count all caffeine sources, especially in pregnancy. |
Who should check first 7
| Situation | Advice | Evidence |
|---|---|---|
| Pregnancy | Green tea is not banned in pregnancy, but it counts toward the daily caffeine limit. No source read covers green tea extract capsules in pregnancy, so ask a clinician before using them. | Authoritative guidance 29 28 |
| Breastfeeding | LactMed reports infant fussiness and poor sleep only with extremely high maternal caffeine. No studies of green tea extract in breastfeeding were found. | Authoritative guidance 16 |
| Infants and young children | Do not give tea to infants. LactMed says it can interfere with iron absorption and cause anemia. Avoid caffeinated drinks for children under 2 (FDA, quoting the Dietary Guidelines). | Authoritative guidance 16 27 |
| Liver disease or past liver injury from a supplement | Ask a clinician before using green tea extract capsules or tablets, because of the liver injury reports. The sources read do not give a rule for brewed tea in liver disease. | Precaution from liver reports 17 4 |
| Low iron or anemia | Ask a clinician. Tea can lower iron absorption. | Human study 9 7 |
| Taking warfarin, nadolol, a statin or raloxifene | Ask your pharmacist or prescriber before changing how much green tea or extract you take. | Authoritative guidance 23 28 |
| Allergy or intolerance to rice or tea | No source read covers allergy to genmaicha. If you react to rice or to tea, avoid it and ask a doctor. | Precaution |
Overdose, product quality and regulators
Summary. Brewed green tea has no safety concerns reported for adults (NCCIH). The main toxicity concern is the liver, linked to concentrated catechin-rich extract taken in large single doses.
Animal. The Hu systematic review says lab studies show the liver as target organ, strongly tied to dosing conditions such as a large single dose by gavage and fasting, and to total catechin and EGCG content.
Human doses studied. EFSA found that high-dose EGCG taken as a food supplement raised liver enzymes in trials (the threshold is in the opinion). The Minnesota Green Tea Trial gave a high-dose extract for 12 months.
High dose or long term signals. Liver enzyme rises with long high-dose extract use; differences by gene variant in one secondary analysis.
Overdose response. Not described in the sources read.
Genotoxicity. Not read.
Toxic or hazardous parts. Leaf is the part used; stems are also in tea (LactMed). No source read compared other parts.
Quality was checked for fluoride and for acrylamide from roasting. Sources read gave no measured lead, cadmium, arsenic, aluminium or pesticide values for genmaicha, green tea or roasted rice tea, so that is unknown here, not shown safe.
Acrylamide from roasting. Acrylamide forms when starchy grain is roasted (EFSA). Roasted barley tea grain held 200 to 600 micrograms per kg and roasted foods including hoji-cha and mugi-cha 116 to 567 ng/g in Japanese analyses; a lab study of roasted brown rice tea found acrylamide too, and less when the rice was germinated first. These are dry roasted products, not brewed cups, and none is genmaicha. 30 22 18 14 24
Fluoride. Tea leaves take up fluoride. A scoping review of 88 studies gave average levels of brick tea 4.78 mg/L, black tea 2.73, green tea 1.37, white tea 0.49 and herbal tea 0.17; longer brewing released more. A Canary Islands study found black and mixed teas could give children aged 4 to 8 a large share of the EFSA upper limit; the abstract did not give green tea. 11 21
Heavy metals and pesticides. Not found in the sources read for green tea. Not described is not proof of none.
Supplement quality. LactMed notes that dietary supplements are not pre-approved by the FDA and labelled and actual ingredients and amounts can differ. In the case report, lab analysis of the capsules found no contaminants but a very high EGCG level. 16 19
| Body | Action | Date |
|---|---|---|
| EFSA (European Union) | Acrylamide topic page: forms in starchy foods during roasting and other high-heat cooking; the 2015 risk assessment concluded dietary acrylamide potentially increases cancer risk in all age groups. It does not name genmaicha, tea or rice. source | 2015 (risk assessment); page read 2026-10-25 |
| NCCIH (NIH) (United States) | Says no safety concerns have been reported for green tea as a beverage in adults; lists extract side effects, rare liver injury, medicine interactions and a caffeine caution in pregnancy. Notes the FDA has approved a specific green tea extract ointment as a prescription drug for genital warts (a topical drug, not a drink or supplement). source | 2025-02 |
| EFSA (European Union) | Opinion on safety of green tea catechins: infusions prepared the traditional way are in general considered safe at EU intakes; rare liver injury after infusions; high-dose EGCG supplements raised liver enzymes in trials. source | 2018-04 |
| EMA / HMPC (European Union) | Has a final EU herbal monograph and assessment report for Camellia sinensis non fermentatum folium (green tea); EMA page lists the therapeutic area as "Fatigue and weakness". source | 2014-04-29 (monograph); 2022-09-26 (assessment addendum) |
| NICHD LactMed (United States) | Notes caffeine-related infant fussiness only at extremely high maternal intake; tea directly to infants can cause anemia; no oral extract data in breastfeeding. source | 2006 |
| NHS (United Kingdom) | Pregnancy: no more than 200 mg of caffeine a day. source | 2026-06-15 |
| US FDA (United States) | Caffeine consumer update: 400 mg a day not generally associated with harm in most adults; lists signs of too much caffeine. source | 2024-08-28 |
| IARC (WHO) (International) | Very hot beverages probably carcinogenic to humans (Group 2A); temperature, not the drink, appears responsible. source | 2016-06-15 |
When to get medical help
- Yellow skin or eyes, dark urine, pale stools, strong tiredness, itching or pain in the upper right belly while using green tea extract: stop it and get medical care now.
- Chest pain, a racing or irregular heartbeat, fainting: call emergency services.
- Black stools, unusual bruising or bleeding if you take warfarin: contact your prescriber or emergency services.
- Very pale skin, breathlessness or marked tiredness in someone who drinks a lot of tea and has low iron: see a clinician.
Stop using the product and contact a clinician or emergency service. In the US, Poison Control is 1-800-222-1222.
General information only, not medical advice. Ask a clinician or pharmacist before use, especially with medicines, in pregnancy or with a health condition. See the Natural Remedy Safety guide.
Frequently asked questions
What is genmaicha?
Does genmaicha have caffeine?
Does the roasted rice add any health benefit?
Not shown. We found no human study of roasted rice tea. The studies we found are food-chemistry work on sugars, amino acids and acrylamide in roasted brown rice. Any benefit would have to come from the tea part, and even that evidence is weak.
Is genmaicha the same as green tea extract?
Is there acrylamide in genmaicha?
Probably some, but nobody has measured it. Roasting starchy grain forms acrylamide, and Japanese analyses found it in roasted barley tea grain and roasted green tea. A lab study found it in roasted brown rice for tea, and less when the rice was germinated first. EFSA says acrylamide in food potentially increases cancer risk for all ages.
Does green tea lower cholesterol, blood pressure or weight?
Maybe slightly for cholesterol and blood pressure. A 2011 pooled analysis found small falls in total and LDL cholesterol, and a 2025 review of 36 trials found about 1 mmHg lower blood pressure, with big differences between trials. A 2020 review of short tea trials found no effect. A Cochrane review found almost no weight change outside Japan. None of this is about genmaicha, and most trials mix drinks and extracts.
Does green tea prevent cancer or help people live longer?
This has not been shown. A Cochrane review of 142 studies found limited, inconsistent, low-certainty evidence on cancer. In Japan, people who drank five or more cups a day had lower all-cause and heart death rates than those who drank less than one cup. This is an association and may reflect other habits. None of it is about genmaicha.
Does green tea help focus, memory or mood?
A review of 21 mostly small studies reported better attention and memory and less anxiety, mainly from caffeine and L-theanine together. It mixes drinks, extracts and single compounds, so certainty is low. Observational data on dementia are mixed and very low certainty. Genmaicha was not studied.
Does green tea help with diabetes?
A meta-analysis of 14 trials found no significant effect of green tea supplements on fasting glucose, insulin or HbA1c in people with type 2 diabetes. Talk to your doctor before changing diabetes care.
Can green tea hurt the liver?
The drink rarely does. NCCIH reports no safety concerns for the beverage in adults, and liver injury is mostly linked to extract capsules and tablets. EFSA noted rare cases after infusions, likely an individual reaction. Stop any extract and get medical care if you notice yellow skin or eyes or dark urine.
Is genmaicha safe in pregnancy, breastfeeding or for children?
Genmaicha has caffeine from its tea part, so it counts toward your daily limit. The NHS says no more than 200 mg of caffeine a day in pregnancy. LactMed reports infant fussiness only at extremely high maternal caffeine. Do not give tea to infants, and the FDA quotes guidance to avoid caffeinated drinks for children under 2. Ask a clinician about extract capsules.
Does genmaicha affect iron or interact with medicines?
Tea polyphenols lowered iron absorption from a meal in a lab study (green tea was not tested), and a 2024 case report links moderate green tea with severe iron-deficiency anemia. NCCIH says high doses of green tea lowered blood levels of nadolol, and one 1999 case report links very large amounts of green tea with a weaker warfarin effect. Ask your pharmacist or prescriber.
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Editorial transparency
- Written by
- AlternativeMed editorial team. Research compiled with AI assistance, then checked against PubMed records.
- Medical review
- None. This page has not been reviewed by a physician or pharmacist.
- First published
- 2026-10-25
- Last substantive update
- 2026-10-25
- How we research
- We built this page from our green tea profile, whose PubMed abstracts were read on 2026-10-25, and searched PubMed for genmaicha and roasted rice tea. We found no clinical study of either, and four food-chemistry papers on acrylamide and roasted grain (abstracts read). The NCCIH and EFSA acrylamide pages were read in full; LiverTox and LactMed were read only as PubMed summary records. Plant names were checked in GBIF. Certainty ratings are the compiler's own reading. No funding statement was read for most papers, so industry links are not ruled out.
- How we rate evidence
- See "How we rate evidence" in the Evidence tab.
- Independence
- No product is promoted on this page. No affiliate links are shown. This page is information, not a recommendation to drink or take anything.
Sources 36
Each source was opened and checked. Where we read only the abstract, it says so. The small numbers in the text point here.
- Abe SK, Saito E, Sawada N, et al. Green tea consumption and mortality in Japanese men and women: a pooled analysis of eight population-based cohort studies in Japan. European Journal of Epidemiology. 2019. PMID 31392470. DOI 10.1007/s10654-019-00545-y. (abstract)
- Acosta L, Byham-Gray L, Kurzer M, et al. Hepatotoxicity with High-Dose Green Tea Extract: Effect of Catechol-O-Methyltransferase and Uridine 5-Diphospho-glucuronosyltransferase 1A4 Genotypes. Journal of Dietary Supplements. 2023. PMID 36178169. DOI 10.1080/19390211.2022.2128501. (abstract)
- Asbaghi O, Fouladvand F, Gonzalez MJ, et al. Effect of green tea on glycemic control in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Diabetes & Metabolic Syndrome. 2021. PMID 33285391. DOI 10.1016/j.dsx.2020.11.004. (abstract)
- EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Younes M, Aggett P, et al. Scientific opinion on the safety of green tea catechins. EFSA Journal. 2018. PMID 32625874. DOI 10.2903/j.efsa.2018.5239. (abstract)
- Filippini T, Malavolti M, Borrelli F, et al. Green tea (Camellia sinensis) for the prevention of cancer. Cochrane Database of Systematic Reviews. 2020. PMID 32118296. DOI 10.1002/14651858.CD005004.pub3. (abstract)
- Hartley L, Flowers N, Holmes J, et al. Green and black tea for the primary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews. 2013. PMID 23780706. DOI 10.1002/14651858.CD009934.pub2. (abstract)
- He Y, Chen J. Severe iron-deficiency anemia after short-term moderate consumption of green tea in woman: A rare case report. Heliyon. 2024. PMID 39263133. DOI 10.1016/j.heliyon.2024.e36666. (abstract)
- Hu J, Webster D, Cao J, et al. The safety of green tea and green tea extract consumption in adults - Results of a systematic review. Regulatory Toxicology and Pharmacology. 2018. PMID 29580974. DOI 10.1016/j.yrtph.2018.03.019. (abstract)
- Hurrell RF, Reddy M, Cook JD. Inhibition of non-haem iron absorption in man by polyphenolic-containing beverages. British Journal of Nutrition. 1999. PMID 10999016. (abstract)
- Igho-Osagie E, Cara K, Wang D, et al. Short-Term Tea Consumption Is Not Associated with a Reduction in Blood Lipids or Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of Nutrition. 2020. PMID 33188386. DOI 10.1093/jn/nxaa295. (abstract)
- Jayasingha H, Amarasooriya G, Rajapaksha N, et al. Fluoride in tea: accumulation, dietary exposure, and future strategies for risk mitigation in food safety; a scoping review. Critical Reviews in Food Science and Nutrition. 2025. PMID 40504749. DOI 10.1080/10408398.2025.2516756. (abstract)
- Jurgens TM, Whelan AM, Killian L, et al. Green tea for weight loss and weight maintenance in overweight or obese adults. Cochrane Database of Systematic Reviews. 2012. PMID 23235664. DOI 10.1002/14651858.CD008650.pub2. (abstract)
- Kakutani S, Watanabe H, Murayama N. Green Tea Intake and Risks for Dementia, Alzheimer's Disease, Mild Cognitive Impairment, and Cognitive Impairment: A Systematic Review. Nutrients. 2019. PMID 31137655. DOI 10.3390/nu11051165. (abstract)
- Kim HJ, Han JA, Lim ST, et al. Effects of germination and roasting on physicochemical and sensory characteristics of brown rice for tea infusion.. Food Chemistry. 2021. PMID 33618097. DOI 10.1016/j.foodchem.2021.129240. (abstract)
- Mancini E, Beglinger C, Drewe J, et al. Green tea effects on cognition, mood and human brain function: A systematic review. Phytomedicine. 2017. PMID 28899506. DOI 10.1016/j.phymed.2017.07.008. (abstract)
- NICHD / NLM. Drugs and Lactation Database (LactMed): Green Tea. LactMed (NCBI Bookshelf). 2006. PMID 30000907. (abstract)
- NIDDK. LiverTox: Green Tea (Clinical and Research Information on Drug-Induced Liver Injury). LiverTox (NCBI Bookshelf). 2012. PMID 31643260. (abstract)
- Ono H, Chuda Y, Ohnishi-Kameyama M, et al. Analysis of acrylamide by LC-MS/MS and GC-MS in processed Japanese foods.. Food Additives and Contaminants. 2003. PMID 12623644. DOI 10.1080/0265203021000060887. (abstract)
- Pillukat MH, Bester C, Hensel A, et al. Concentrated green tea extract induces severe acute hepatitis in a 63-year-old woman - a case report with pharmaceutical analysis. Journal of Ethnopharmacology. 2014. PMID 24862489. DOI 10.1016/j.jep.2014.05.015. (abstract)
- Rezaei M, Akhavan N, Fathi F, et al. Effect of green tea supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomised controlled trials. Blood Pressure. 2025. PMID 40497293. DOI 10.1080/08037051.2025.2517122. (abstract)
- Rodriguez I, Burgos A, Rubio C, et al. Human exposure to fluoride from tea (Camellia sinensis) in a volcanic region - Canary Islands, Spain. Environmental Science and Pollution Research. 2020. PMID 32740848. DOI 10.1007/s11356-020-10319-9. (abstract)
- Takatsuki S, Nemoto S, Sasaki K, et al. Determination of acrylamide in processed foods by LC/MS using column switching.. Shokuhin Eiseigaku Zasshi. 2003. PMID 12846155. DOI 10.3358/shokueishi.44.89. (abstract)
- Taylor JR, Wilt VM. Probable antagonism of warfarin by green tea. Annals of Pharmacotherapy. 1999. PMID 10332534. DOI 10.1345/aph.18238. (abstract)
- Yoshida M, Ono H, Chuda Y, et al. Acrylamide in Japanese processed foods and factors affecting acrylamide level in potato chips and tea.. Advances in Experimental Medicine and Biology. 2005. PMID 16438315. DOI 10.1007/0-387-24980-X_31. (abstract)
- Zheng XX, Xu YL, Li SH, et al. Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials. American Journal of Clinical Nutrition. 2011. PMID 21715508. DOI 10.3945/ajcn.110.010926. (abstract)
- n/a. IARC (WHO): Press release no. 244, coffee, mate and very hot beverages (15 June 2016). n/a. 2016. (full-text)
- n/a. FDA: Spilling the Beans: How Much Caffeine Is Too Much? (content current as of 28 Aug 2024). n/a. 2024. (full-text)
- n/a. NCCIH (NIH): Green Tea: Usefulness and Safety (last updated February 2025). n/a. 2025. (full-text)
- n/a. NHS (UK): Foods to avoid in pregnancy (page last reviewed 15 June 2026). n/a. 2026. (full-text)
- n/a. EFSA: Acrylamide topic page (read 2026-10-25). n/a. 2026. (full-text)
- n/a. EMA: Camelliae sinensis non fermentatum folium (green tea), herbal medicinal product page. n/a. 2026. (abstract)
- n/a. PubChem: epigallocatechin gallate (CID 65064), formula C22H18O11. n/a. 2026. (full-text)
- n/a. PubChem: caffeine (CID 2519), formula C8H10N4O2. n/a. 2026. (full-text)
- n/a. PubChem: L-theanine (CID 439378), formula C7H14N2O3. n/a. 2026. (full-text)
- n/a. GBIF Backbone Taxonomy: Camellia sinensis (L.) Kuntze (usage key 3189635), retrieved 2026-10-25. n/a. 2026. (full-text)
- n/a. GBIF Backbone Taxonomy: Oryza sativa L. (usage key 2703459), retrieved 2026-10-25. n/a. 2026. (full-text)
Where to buy
Check the label first. Whatever you buy, look for these:
- The herb is the first or only ingredient
- Organic or lab-tested if that matters to you
- Loose leaf or tea bags, and how long they have been stored
- If you take medicines or are pregnant, ask a pharmacist about the herb first
Talk to a pharmacist or doctor before you start any supplement, especially if you take medicines. See the Safety tab for interactions.
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